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Anti-inflammatory therapy with nebulized dornase alfa for severe COVID-19 pneumonia: a randomized unblinded trial Porter, Joanna C.; Inshaw, Jamie; Solis, Vincente Joel; Denneny, Emma; Evans, Rebecca; Temkin, Mia, I; De Vasconcelos, Nathalia; Aramburu, Iker Valle; Hoving, Dennis; Basire, Donna; Crissell, Tracey; Guinto, Jesusa; Webb, Alison; Esmail, Hanif; Johnston, Victoria; Last, Anna; Rampling, Thomas; Lippert, Lena; Helbig, Elisa Theresa; Kurth, Florian; Williams, Bryan; Flynn, Aiden; Lukey, Pauline T.; Birault, Veronique; Papayannopoulos, Venizelos 分享 收藏
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Human endogenous retrovirus onco-exaptation counters cancer cell senescence through calbindin Attig, Jan; Pape, Judith; Doglio, Laura; Kazachenka, Anastasiya; Ottina, Eleonora; Young, George R.; Enfield, Katey S. S.; Aramburu, Iker Valle; Ng, Kevin W.; Faulkner, Nikhil; Bolland, William; Papayannopoulos, Venizelos; Swanton, Charles; Kassiotis, George 分享 收藏
Loss of TET2 in human hematopoietic stem cells alters the development and function of neutrophils Encabo, Hector Huerga; Aramburu, Iker Valle; Garcia-Albornoz, Manuel; Piganeau, Marion; Wood, Henry; Song, Anna; Ferrelli, Alessandra; Sharma, Aneesh; Minutti, Carlos M.; Domart, Marie-Charlotte; Papazoglou, Despoina; Gurashi, Kristian; Sopena, Miriam Llorian; Goldstone, Robert; Fallesen, Todd; Wang, Qian; Ariza-McNaughton, Linda; Wiseman, Daniel H.; Batta, Kiran; Gupta, Rajeev; Papayannopoulos, Venizelos; Bonnet, Dominique 分享 收藏
Functional proteomic profiling links deficient DNA clearance with increased mortality in individuals with severe COVID-19 pneumonia Aramburu, Iker Valle; Hoving, Dennis; Vernardis, Spyros, I; Tin, Martha C. F.; Ioannou, Marianna; Temkin, Mia, I; De Vasconcelos, Nathalia M.; Demichev, Vadim; Helbig, Elisa Theresa; Lippert, Lena; Stahl, Klaus; White, Matthew; Radbruch, Helena; Ihlow, Jana; Horst, David; Chiesa, Scott T.; Deanfield, John E.; David, Sascha; Bode, Christian; Kurth, Florian; Ralser, Markus; Papayannopoulos, Venizelos 分享 收藏
Microbe capture by splenic macrophages triggers sepsis via T cell-death-dependent neutrophil lifespan shortening Ioannou, Marianna; Hoving, Dennis; Aramburu, Iker Valle; Temkin, Mia, I; De Vasconcelos, Nathalia M.; Tsourouktsoglou, Theodora-Dorita; Wang, Qian; Boeing, Stefan; Goldstone, Robert; Vernardis, Spyros; Demichev, Vadim; Ralser, Markus; David, Sascha; Stahl, Klaus; Bode, Christian; Papayannopoulos, Venizelos 分享 收藏
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Human Erythroid Progenitors Are Directly Infected by SARS-CoV-2: Implications for Emerging Erythropoiesis in Severe COVID-19 Patients Encabo, Hector Huerga; Grey, William; Garcia-Albornoz, Manuel; Wood, Henry; Ulferts, Rachel; Aramburu, Iker Valle; Kulasekararaj, Austin G.; Mufti, Ghulam; Papayannopoulos, Venizelos; Beale, Rupert; Bonnet, Dominique 分享 收藏
The receptor DNGR-1 signals for phagosomal rupture to promote cross-presentation of dead-cell-associated antigens (vol 22, pg 140, 2021) Canton, Johnathan; Blees, Hanna; Henry, Conor M.; Buck, Michael D.; Schulz, Oliver; Rogers, Neil C.; Childs, Eleanor; Zelenay, Santiago; Rhys, Hefin; Domart, Marie-Charlotte; Collinson, Lucy; Alloatti, Andres; Ellison, Cara J.; Amigorena, Sebastian; Papayannopoulos, Venizelos; Thomas, David C.; Randow, Felix; Sousa, Caetano 分享 收藏
The receptor DNGR-1 signals for phagosomal rupture to promote cross-presentation of dead-cell-associated antigens Canton, Johnathan; Blees, Hanna; Henry, Conor M.; Buck, Michael D.; Schulz, Oliver; Rogers, Neil C.; Childs, Eleanor; Zelenay, Santiago; Rhys, Hefin; Domart, Marie-Charlotte; Collinson, Lucy; Alloatti, Andres; Ellison, Cara J.; Amigorena, Sebastian; Papayannopoulos, Venizelos; Thomas, David C.; Randow, Felix; Reis e Sousa, Caetano 分享 收藏
Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis Moreira-Teixeira, Lucia; Stimpson, Philippa J.; Stavropoulos, Evangelos; Hadebe, Sabelo; Chakravarty, Probir; Ioannou, Marianna; Aramburu, Iker Valle; Herbert, Eleanor; Priestnall, Simon L.; Suarez-Bonnet, Alejandro; Sousa, Jeremy; Fonseca, Kaori L.; Wang, Qian; Vashakidze, Sergo; Rodriguez-Martinez, Paula; Vilaplana, Cristina; Saraiva, Margarida; Papayannopoulos, Venizelos; O'Garra, Anne 分享 收藏
Scalable and robust SARS-CoV-2 testing in an academic center (vol 47, pg 613, 2020) Aitken, Jim; Ambrose, Karen; Barrell, Sam; Beale, Rupert; Bineva-Todd, Ganka; Biswas, Dhruva; Byrne, Richard; Caidan, Simon; Cherepanov, Peter; Churchward, Laura; Clark, Graham; Crawford, Margaret; Cubitt, Laura; Dearing, Vicky; Earl, Christopher; Edwards, Amelia; Ekin, Chris; Fidanis, Efthymios; Gaiba, Alessandra; Gamblin, Steve; Gandhi, Sonia; Goldman, Jacki; Goldstone, Robert; Grant, Paul R.; Greco, Maria; Heaney, Judith; Hindmarsh, Steve; Houlihan, Catherine F.; Howell, Michael; Hubank, Michael; Hughes, Deborah; Instrell, Rachael; Jackson, Deborah; Jamal-Hanjani, Mariam; Jiang, Ming; Johnson, Mark; Jones, Leigh; Kanu, Nnennaya; Kassiotis, George; Kirk, Stuart; Kjaer, Svend; Levett, Andrew; Levett, Lisa; Levi, Marcel; Lu, Wei-Ting; MacRae, James I.; Matthews, John; Mccoy, Laura E.; Moore, Catherine; Moore, David; Nastouli, Eleni; Nicod, Jerome; Nightingale, Luke; Olsen, Jessica; O'Reilly, Nicola; Pabari, Amar; Papayannopoulos, Venizelos; Patel, Namita; Peat, Nigel; Pollitt, Marc; Ratcliffe, Peter; Reis e Sousa, Caetano; Rosa, Annachiara; Rosenthal, Rachel; Roustan, Chloe; Rowan, Andrew; Shin, Gee Yen; Snell, Daniel M.; Song, Ok-Ryul; Spyer, Moira J.; Strange, Amy; Swanton, Charles; Turner, James M. A.; Turner, Melanie; Wack, Andreas; Walker, Philip A.; Ward, Sophia; Wong, Wai Keong; Wright, Joshua; Wu, Mary 分享 收藏
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Scalable and robust SARS-CoV-2 testing in an academic center Aitken, Jim; Ambrose, Karen; Barrell, Sam; Beale, Rupert; Bineva-Todd, Ganka; Biswas, Dhruva; Byrne, Richard; Caidan, Simon; Cherepanov, Peter; Churchward, Laura; Clark, Graham; Crawford, Margaret; Cubitt, Laura; Dearing, Vicky; Earl, Christopher; Edwards, Amelia; Ekin, Chris; Fidanis, Efthymios; Gaiba, Alessandra; Gamblin, Steve; Gandhi, Sonia; Goldman, Jacki; Goldstone, Robert; Grant, Paul R.; Greco, Maria; Heaney, Judith; Hindmarsh, Steve; Houlihan, Catherine F.; Howell, Michael; Hubank, Michael; Hughes, Deborah; Instrell, Rachael; Jackson, Deborah; Jamal-Hanjani, Mariam; Jiang, Ming; Johnson, Mark; Jones, Leigh; Kanu, Nnennaya; Kassiotis, George; Kirk, Stuart; Kjaer, Svend; Levett, Andrew; Levett, Lisa; Levi, Marcel; Lu, Wei-Ting; MacRae, James I.; Matthews, John; McCoy, Laura E.; Moore, Catherine; Moore, David; Nastouli, Eleni; Nicod, Jerome; Nightingale, Luke; Olsen, Jessica; O'Reilly, Nicola; Pabari, Amar; Papayannopoulos, Venizelos; Patel, Namita; Peat, Nigel; Pollitt, Marc; Ratcliffe, Peter; Sousa, Caetano; Rosa, Annachiara; Rosenthal, Rachel; Roustan, Chloe; Rowan, Andrew; Shin, Gee Yen; Snell, Daniel M.; Song, Ok-Ryul; Spyer, Moira J.; Strange, Amy; Swanton, Charles; Turner, James M. A.; Turner, Melanie; Wack, Andreas; Walker, Philip A.; Ward, Sophia; Wong, Wai Keong; Wright, Joshua; Wu, Mary 分享 收藏
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Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases 转录谱揭示了跨疾病的血液和组织中的I型和II型干扰素网络 Singhania, Akul; Graham, Christine M.; Gabrysova, Leona; Moreira-Teixeira, Lucia; Stavropoulos, Evangelos; Pitt, Jonathan M.; Chakravarty, Probir; Warnatsch, Annika; Branchett, William J.; Conejero, Laura; Lin, Jing-Wen; Davidson, Sophia; Wilson, Mark S.; Bancroft, Gregory; Langhorne, Jean; Frickel, Eva; Sesay, Abdul K.; Priestnall, Simon L.; Herbert, Eleanor; Ioannou, Marianna; Wang, Qian; Humphreys, Ian R.; Dodd, Jonathan; Openshaw, Peter J. M.; Mayer-Barber, Katrin D.; Jankovic, Dragana; Sher, Alan; Lloyd, Clare M.; Baldwin, Nicole; Chaussabel, Damien; Papayannopoulos, Venizelos; Wack, Andreas; Banchereau, Jacques F.; Pascual, Virginia M.; O'Garra, Anne 分享 收藏