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何思雨 封面图

何思雨 (Siyu He)

Sichuan University

37H指数
175论文数
4.3K被引数
收录论文 88
发表时间
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Author Correction: A longitudinal cohort study uncovers plasma protein biomarkers predating clinical onset and treatment response of rheumatoid arthritis作者更正：一项纵向队列研究揭示了在类风湿关节炎临床发作和治疗应答前出现的血浆蛋白质生物标志物
errNature Communications
IF15.7
err2026-09-22
err0
errOAAI
errSiyu He; Chenxi Zhu; Yi Liu; Zhiqiang Xu; Rui Sun; Bin Yang; Xin Guo; Martin Herrmann i; Luis E. Muñoz; Inger Gjertsson; Rikard Holmdahl; Lunzhi Dai; Yi Zhao
err分享
err收藏
Nickel-Catalyzed Three-Component Difluoroalkylation-Amination for the Direct Access to Anti-Inflammatory β-Difluoroalkyl Amines镍催化三组分双氟烷基化-胺化反应用于直接制备抗炎β-双氟烷基胺
errAdvanced Science
IF14.1
err2026-08-04
err0
errOAAI
errChang Xu; Fangting Ma; Fan Ding; Luyan Wang; Yunxi Li; Yunzhi He; Xingang Zhang; Siyu He; Dandan Liu
err分享
err收藏
Inhalable ligustrazine powders relieve inflammation of COPD via regulation of neutrophil extracellular traps and gut-lung axis microbiota吸入型川芎嗪粉末通过调节中性粒细胞胞外诱捕网和肠道-肺轴微生物组缓解COPD炎症
errScientific Reports
IF3.9
err2026-07-30
err0
errOAAI
errXuejing Luan; Mengyao Shi; Di Wu; Siyu He; Jinghui Xie; Xiangli Tong; Jiabing Tong; Zegeng Li; Jiwen Zhang; Jie Zhu
err分享
err收藏
Regulation of different kinases for Alzheimer's disease therapy: progresses and perspectives
errBioorganic Chemistry
IF4.7
err2026-07-25
err0
PREAI
errMenglin Han; Qinghong Liao; Siyu He; Lina Guo; Ziyao Lu; Xiaohan Wang; Wen Sun; Yuetong Duan; Weiping Lyu; Qi Li
err分享
err收藏
Corrigendum to “Epigenetically activated MIR100HG regulates UPF1-mediated oxidative stress to promote pulmonary vascular immune microenvironment remodeling” [Free Radic. Biol. Med. 244 (2026) 210-228]勘误：题为“Epigenetically activated MIR100HG regulates UPF1-mediated oxidative stress to promote pulmonary vascular immune microenvironment remodeling”的论文（Free Radic. Biol. Med. 244 (2026) 210-228）
errFree Radical Biology and Medicine
IF8.2
err2026-03-11
err0
PREAI
errLanglin Ou; Yingli Chen; Ao Shen; Siyu He; Jian Mei; Zitong Meng; Hao Yuan; Xiaoying Wang; Xiangrui Zhu; Lixin Zhang; Yan Xing; Fei Li; Song Wang; Xiangming Pang; Yuxiang Liu; Cui Ma
err分享
err收藏
Epigenetically activated MIR100HG regulates UPF1-mediated oxidative stress to promote pulmonary vascular immune microenvironment remodeling表观遗传激活的MIR100HG通过调控UPF1介导的氧化应激来促进肺血管免疫微环境的重塑
errFree Radical Biology and Medicine
IF8.2
err2025-12-04
err0
PREAI
errLanglin Ou; Yingli Chen; Ao Shen; Siyu He; Jian Mei; Zitong Meng; Hao Yuan; Xiaoying Wang; Xiangrui Zhu; Lixin Zhang; Yan Xing; Fei Li; Song Wang; Xiangming Pang; Yuxiang Liu; Cui Ma
err分享
err收藏
Squidiff: predicting cellular development and responses to perturbations using a diffusion modelSquidiff：使用扩散模型预测细胞发育和对扰动的响应
errNature Methods
IF32.1
err2025-11-03
err0
PREAI
errSiyu He; Yuefei Zhu; Daniel Naveed Tavakol; Haotian Ye; Yeh-Hsing Lao; Zixian Zhu; Cong Xu; Shradha Chauhan; Guy Garty; Raju Tomer; Gordana Vunjak-Novakovic; James Zou; Elham Azizi; Kam W. Leong
err分享
err收藏
Modified uvulopalatopharyngoplasty: 8 suture abduction-suspension of the palatopharyngeal muscle改良悬雍垂腭咽成形术：腭咽肌的8字缝合外展悬吊
errAMERICAN JOURNAL OF OTOLARYNGOLOGY
IF1.7
err2025-10-01
err0
errOAAI
errXu, Yingxiang; Zhu, Shan; Li, Jinlian; He, Siyu; Yu, Riqing; Hong, Haiyu; He, Peng
err分享
err收藏
A Longitudinal Study Reveals Metabolomic Markers for Individuals at Risk, Disease Severity, and Treatment Response in Rheumatoid Arthritis一项纵向研究揭示了类风湿关节炎中高风险个体、疾病严重程度及治疗反应的代谢组学标志物。
errAdvanced Science
IF14.1
err2025-08-13
err0
errOAAI
errChenxi Zhu; Jiayi Xu; Siyu He; Qian Niu; Yi Liu; Xin Guo; Huifang Hu; Rui Sun; Tao Chen; Yan Liu; Zhiqiang Xu; Na Jiang; Lipu Yao; Lunzhi Dai; Qinghua Zou; Fanxin Zeng; Liesu Meng; Inger Gjertsson; Rikard Holmdahl; Bin Yang; Dan Du; Yi Zhao
err分享
err收藏
BERTopic_Teen: a multi-module optimization approach for short text topic modeling in adolescent healthBERTopic_Teen：一种针对青少年健康领域短文本主题建模的多模块优化方法
errFrontiers in Public Health
IF3.4
err2025-08-12
err0
errOAAI
errYiqiang Feng†; Ziao Chen†; Yuxin Zhang; Wenyuan Huang; Xuanming Zhang; Siyu He
err分享
err收藏
Quantifying large language model usage in scientific papers量化科学论文中的大型语言模型使用情况
errNature Human Behaviour
IF15.9
err2025-08-04
err0
PREAI
errWeixin Liang; Yaohui Zhang; Zhengxuan Wu; Haley Lepp; Wenlong Ji; Xuandong Zhao; Hancheng Cao; Sheng Liu; Siyu He; Zhi Huang; Diyi Yang; Christopher Potts; Christopher D. Manning; James Zou
err分享
err收藏
Multi-omics analysis reveals immunosuppression in oesophageal squamous cell carcinoma induced by creatine accumulation and HK3 deficiency多组学分析揭示了由肌酸积累和HK3缺乏诱导的食管鳞状细胞癌中的免疫抑制
errGENOME MEDICINE
IF11.2
err2025-05-06
err0
errOAAI
errGao, Yingzhen; He, Siyu; Meng, Xiaoyan; Zheng, Kun; Cui, Heyang; Cheng, Yikun; Shen, Xinyuan; Zhai, Yuanfang; Zou, Binbin; Wang, Fang; Li, Hongyi; Kong, Pengzhou; Wang, Yanqiang; Feng, Xuefei; Yang, Bin; Sun, Ruifang; Meng, Yongsheng; Xu, Enwei; Guo, Yanlin; Ding, Ning; Zhang, Weimin; Cui, Yongping; Zhang, Ling
err分享
err收藏
Targeting CCR5 with miltefosine as a therapeutic strategy for thrombocytopenia以米特fosine靶向CCR5作为治疗血小板减少症的一种治疗策略
errISCIENCE
IF4.1
err2025-05-01
err0
errOAAI
errLi, Qinyao; Zhang, Ting; Li, Zhichao; Qi, Xiao; Mei, Xinyue; Liu, Sheng; He, Siyu; Qiao, Gan; Li, Rong; Shen, Hongping; Zeng, Jing; Huang, Feihong; Dai, Shuang; Li, Sirui; Luo, Jiesi; Wu, Jianming
err分享
err收藏
Original Multimodal discovery of bavachinin A: A natural FLT3 agonist for treating thrombocytopenia多模态发现巴娃西尼A：一种治疗血小板减少症的天然FLT3激动剂
errPHYTOMEDICINE
IF8.3
err2025-05-01
err0
PREAI
errWang, Long; Zhang, Ting; Yang, Xin; Mo, Qi; Ran, Mei; Li, Rong; Yang, Bo; Shen, Hongping; Li, Qinyao; Li, Zhichao; Jiang, Nan; Zeng, Jing; Xie, Xiang; He, Siyu; Huang, Feihong; Zhang, Chunxiang; Luo, Jiesi
err分享
err收藏
Development of a Novel Nanoclay-Doped Hydrogel Adsorbent for Efficient Removal of Heavy Metal Ions and Organic Dyes from Wastewater开发一种新型纳米黏土掺杂水凝胶吸附剂，用于高效去除废水中的重金属离子和有机染料
errGELS
IF5.3
err2025-04-14
err1
errOAAI
errZhao, Hang; Xie, Mengmeng; He, Siyu; Lin, Saishi; Liu, Xiuying
err分享
err收藏
A novel therapeutic strategy for leukopenia: Miltefosine activates the Ras/ MEK/ERK pathway to promote neutrophil differentiation一种治疗白细胞减少症的新策略：米特fosine激活Ras/MEK/ERK通路以促进中性粒细胞分化
errBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
IF2.2
err2025-02-01
err0
PREAI
errLi, Qinyao; He, Siyu; Li, Zhichao; Liu, Sheng; Mei, Xinyue; Qi, Xiao; Qiao, Gan; Luo, Jiesi; Shen, Hongping; Zeng, Jing; Huang, Feihong; Gong, Siqi; Chen, Zhicheng; Wu, Jianming; Wang, Long
err分享
err收藏
Comprehensive analysis of scRNA-seq and bulk RNA-seq reveals the non-cardiomyocytes heterogeneity and novel cell populations in dilated cardiomyopathyScrna-seq和bulk rna-seq的综合分析揭示了扩张型心肌病的非心肌细胞异质性和新的细胞群
errJOURNAL OF TRANSLATIONAL MEDICINE
IF7.5
err2025-01-06
err0
errOAAI
errHe, Siyu; Li, Chunyu; Lu, Mingxin; Lin, Fang; Hu, Sangyu; Zhang, Junfang; Peng, Luying; Li, Li
err分享
err收藏
Encoding spatial tumour dynamics with Starfysh
errNATURE REVIEWS CANCER
IF66.8
err2024-10-11
err0
PREAI
errHe, Siyu
err分享
err收藏
Design, Synthesis, Anti-TMV Activity, and Structure-Activity Relationships of Seco-pregnane C21 Steroids and Their Derivatives
errJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
IF6.2
err2024-09-19
err1
PREAI
errYan, Ying; Tang, Pan; He, Siyu; Kong, Xiangkai; Wang, Rong-Hua; Shi, Jing; Zhang, Tianyuan; Di, Ying-tong; Tang, Lei; Hao, Xiao-Jiang
err分享
err收藏
Redox-Neutral Coupling of Allyl Alcohols with Trifluoromethyl Ketones via Synergistic Ni-Ti Bimetallic Catalysis
errORGANIC LETTERS
IF5
err2024-08-26
err0
PREAI
errWang, Rong-Hua; Li, Bo; Gou, Ming-Bai; Luo, Zhen-Qi; Liu, Bin; Li, Yong; Kong, Xiangkai; He, Qing; He, Siyu; Li, Jiang-Fei; Huang, Jiayu; Wang, Jianta; Zhang, Jiquan; Tang, Lei
err分享
err收藏

研究方向

基于计算机辅助药物设计的新型靶向药物的发现设计合成与活性研究活性小分子的成药性优化及分子机制研究药物化学药理学【主持的科研项目】基于结构的新型AKR1C3抑制剂的设计合成及其逆转肝癌对索拉非尼耐药的活性研究【近五年代表性论文】Siyu HeXianglin ChuYujia WuJiheng JiangPengfei FangYuting ChenYang LiuZhixia QiuYibei XiaoZhiyu LiDi PanQian ZhangHuanfang XieShuaishuai XingFeng FengWenyuan LiuQinglong GuoLi ZhaoPeng YangHaopeng SunXiaolong ZhangQi LiWeiping LyuYijun Liu癌症药物耐药性醛酮还原酶1C3抑制剂Qihang Li基于药效团模型与分子对接发现新型ULK1抑制剂【授权发明专利】孙昊鹏刘阳何思雨禇相霖郭青龙赵丽冯锋柳文媛AKR1C3选择性抑制剂AKR1C3抑制剂AKRIC3抑制剂制备方法医药用途
合作学者
合作期刊
A
Antoni Ribas
H 指数: 158 · 论文数: 1.7K
G
Gordana Vunjak‐Novakovic
H 指数: 137 · 论文数: 658
C
Christopher D. Manning
H 指数: 133 · 论文数: 788
K
Kam W. Leong
H 指数: 131 · 论文数: 857
A
Alexander Y. Rudensky
H 指数: 127 · 论文数: 345
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