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The IL-2 SYNTHORIN molecule promotes functionally adapted Tregs in a preclinical model oftype 1 diabetes Alvarez, Fernando; Acuff, Nicole, V; La Muraglia II, Glenn M.; Sabri, Nazila; Milla, Marcos E.; Mooney, Jill M.; Mackey, Matthew F.; Peakman, Mark; Piccirillo, Ciriaco A. 分享 收藏
HLA A*24:02-restricted T cell receptors cross-recognize bacterial and preproinsulin peptides in type 1 diabetes Dolton, Garry; Bulek, Anna; Wall, Aaron; Thomas, Hannah; Hopkins, Jade R.; Rius, Cristina; Galloway, Sarah A. E.; Whalley, Thomas; Tan, Li Rong; Morin, Theo; Omidvar, Nader; Fuller, Anna; Topley, Katie; Hasan, Md Samiul; Jain, Shikha; D'Souza, Nirupa; Hodges-Hoyland, Thomas; Spiller, Owen B.; Kronenberg-Versteeg, Deborah; Szomolay, Barbara; van den Berg, Hugo A.; Jones, Lucy C.; Peakman, Mark; Cole, David K.; Rizkallah, Pierre J.; Sewell, Andrew K. 分享 收藏
The role of OX40 ligand/OX40 axis signalling in atopic dermatitis Guttman-Yassky, Emma; Croft, Michael; Geng, Bob; Rynkiewicz, Natalie; Lucchesi, Davide; Peakman, Mark; van Krinks, Cassandra; Valdecantos, Wendell; Xing, Heming; Weidinger, Stephan 分享 收藏
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A set of circulating microRNAs belonging to the 14q32 chromosome locus identifies two subgroups of individuals with recent-onset type 1 diabetes Sebastiani, Guido; Grieco, Giuseppina Emanuela; Bruttini, Marco; Auddino, Stefano; Mori, Alessia; Toniolli, Mattia; Fignani, Daniela; Licata, Giada; Aiello, Elena; Nigi, Laura; Formichi, Caterina; Fernandez-Tajes, Juan; Pugliese, Alberto; Evans-Molina, Carmella; Overbergh, Lut; Tree, Timothy; Peakman, Mark; Mathieu, Chantal; Dotta, Francesco 分享 收藏
A CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organism Ptacin, Jerod L.; Ma, Lina; Caffaro, Carolina E.; Acuff, Nicole V.; Germar, Kristine; Severy, Peter; Qu, Yanyan; Vela, Jose-Luis; Cai, Xinming; San Jose, Kristine M.; Aerni, Hans R.; Chen, David B.; Esche, Ean; Ismaili, Taylor K.; Herman, Rob; Pavlova, Yelena; Pena, Michael J.; Nguyen, Jasmine; Koriazova, Lilia K.; Shawver, Laura K.; Joseph, Ingrid B.; Mooney, Jill; Peakman, Mark; Milla, Marcos E. 分享 收藏
The INNODIA Type 1 Diabetes Natural History Study: a European cohort of newly diagnosed children, adolescents and adults INNODIA 1型糖尿病自然史研究: 欧洲新诊断的儿童、青少年和成人队列 Marcovecchio, M. Loredana; Hendriks, A. Emile J.; Delfin, Carl; Battelino, Tadej; Danne, Thomas; Evans, Mark L.; Johannesen, Jesper; Kaur, Simranjeet; Knip, Mikael; Overbergh, Lut; Pociot, Flemming; Todd, John A.; van der Schueren, Bart; Wicker, Linda S.; Peakman, Mark; Mathieu, Chantal 分享 收藏
Tryptophan metabolism promotes immune evasion in human pancreatic cells Rachdi, Latif; Zhou, Zhicheng; Berthault, Claire; Lourenco, Chloe; Fouque, Alexis; Domet, Thomas; Armanet, Mathieu; You, Sylvaine; Peakman, Mark; Mallone, Roberto; Scharfmann, Raphael 分享 收藏
Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes distinguishes markers of disease and C-peptide trajectory 新诊断的1型糖尿病青年纵向样本的靶向血清蛋白质组学区分疾病标志物和c肽轨迹 Moulder, Robert; Valikangas, Tommi; Hirvonen, M. Karoliina; Suomi, Tomi A.; Brorsson, Caroline A.; Lietzen, Niina; Bruggraber, Sylvaine F. A.; Overbergh, Lut; Dunger, David B.; Peakman, Mark; Chmura, Piotr J.; Brunak, Soren; Schulte, Anke M.; Mathieu, Chantal; Knip, Mikael; Elo, Laura L.; Lahesmaa, Riitta 分享 收藏
Gene expression signature predicts rate of type 1 diabetes progression Suomi, Tomi; Starskaia, Inna; Kalim, Ubaid Ullah; Rasool, Omid; Jaakkola, Maria K.; Gronroos, Toni; Valikangas, Tommi; Brorsson, Caroline; Mazzoni, Gianluca; Bruggraber, Sylvaine; Overbergh, Lut; Dunger, David; Peakman, Mark; Chmura, Piotr; Brunak, Seren; Schulte, Anke M.; Mathieu, Chantal; Knip, Mikael; Lahesmaa, Riitta; Elo, Laura L. 分享 收藏
Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage 外周血单核细胞中肠病毒RNA的检测与1型糖尿病风险基因IFIH1的易感等位基因的存在以及疾病阶段相关 Sioofy-Khojine, Amir-Babak; Richardson, Sarah J.; Locke, Jonathan M.; Oikarinen, Sami; Nurminen, Noora; Laine, Antti-Pekka; Downes, Kate; Lempainen, Johanna; Todd, John A.; Veijola, Riitta; Ilonen, Jorma; Knip, Mikael; Morgan, Noel G.; Hyoty, Heikki; Peakman, Mark; Eichmann, Martin 分享 收藏
Artificial Antigen Presenting Cells for Detection and Desensitization of Autoreactive T cells Associated with Type 1 Diabetes Artzy-Schnirman, Arbel; Abu-Shah, Enas; Chandrawati, Rona; Altman, Efrat; Yusuf, Norkhairin; Wang, Shih-Ting; Ramos, Jose; Hansel, Catherine S.; Haus-Cohen, Maya; Dahan, Rony; Arif, Sefina; Dustin, Michael L.; Peakman, Mark; Reiter, Yoram; Stevens, Molly M. 分享 收藏
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Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple β-Cell Peptides in Type 1 Diabetes 使用多种 β 细胞肽的抗原特异性免疫疗法对1型糖尿病的免疫和代谢作用 Liu, Yuk-Fun; Powrie, Jake; Arif, Sefina; Yang, Jennie H. M.; Williams, Evangelia; Khatri, Leena; Joshi, Mamta; Lhuillier, Loic; Fountoulakis, Nikolaos; Smith, Emma; Beam, Craig; Lorenc, Anna; Peakman, Mark; Tree, Timothy 分享 收藏
Mapping T Cell Responses to Native and Neo-Islet Antigen Epitopes in at Risk and Type 1 Diabetes Subjects 在风险和1型糖尿病受试者中绘制T细胞对天然和新胰岛抗原表位的反应 Arif, Sefina; Pujol-Autonell, Irma; Kamra, Yogesh; Williams, Evangelia; Yusuf, Norkhairin; Domingo-Vila, Clara; Shahrabi, Yasaman; Pollock, Emily; Khatri, Leena; Peakman, Mark; Tree, Timothy; Lorenc, Anna 分享 收藏
Autoreactive T cell profiles are altered following allogeneic islet transplantation with alemtuzumab induction and re-emerging phenotype is associated with graft function Sabbah, Shereen; Liew, Aaron; Brooks, Augustin M.; Kundu, Rhiannon; Reading, James L.; Flatt, Anneliese; Counter, Claire; Choudhary, Pratik; Forbes, Shareen; Rosenthal, Miranda J.; Rutter, Martin K.; Cairns, Stephanie; Johnson, Paul; Casey, John; Peakman, Mark; Shaw, James A.; Tree, Timothy I. M. 分享 收藏
Follicular helper T cell profiles predict response to costimulation blockade in type 1 diabetes 滤泡辅助T细胞谱可预测1型糖尿病对共刺激阻滞的反应 Edner, Natalie M.; Heuts, Frank; Thomas, Niclas; Wang, Chun Jing; Petersone, Lina; Kenefeck, Rupert; Kogimtzis, Alexandros; Ovcinnikovs, Vitalijs; Ross, Ellen M.; Ntavli, Elisavet; Elfaki, Yassin; Eichmann, Martin; Baptista, Roman; Ambery, Philip; Jermutus, Lutz; Peakman, Mark; Rosenthal, Miranda; Walker, Lucy S. K. 分享 收藏
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