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T

Timothy A. Graubert

Harvard Medical School
H指数:61
被引数:2.5万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Sialylated CD43 forms a glyco-immune barrier that restrains antileukemic immunity

唾液酸化的CD43形成一种糖免疫屏障，该屏障可抑制抗白血病免疫。

Science
IF45.8
2026-04-090
PRE
Jooho Chung; Mounica Vallurupalli; Sarah Noel; Gail Schor; Sofia Mrowka; Ilario Scapozza; Zelalem Demere; Sachin V. Kammula; Margaret Hu; Sarah Y. Kim; YuhJong Liu; Celeste Nobrega; Jonathan J. Perera; Ewa Wrona; Collins K. Cheruiyot; Yunkang Lin; David W. Wu; Maria Saberi; Aidan Cruickshank; Elliot C. Woods; Cun Lan Chuong; Filippo Birocchi; Ashwin V. Kammula; Omar I. Avila; Nelson Knudsen; Mustafa Kocak; John G. Doench; Dean Procter; Lindsey Thornton; Andrew M. Brunner; Eric Winer; Daniel J. DeAngelo; Jacqueline S. Garcia; Richard M. Stone; Russell W. Jenkins; Marcela V. Maus; Timothy A. Graubert; Kathleen B. Yates; Todd R. Golub; Robert T. Manguso
OGFOD1 enables AML chemo- and nutrient stress resistance by regulating protein synthesis

OGFOD1通过调控蛋白质合成使急性髓系白血病（AML）具有化疗和营养应激抗性。

Cell Metabolism
IF30.9
2025-09-160
PRE
Christina Mayerhofer; Dan Li; Trine Kristiansen; Ernst Mayerhofer; Azeem Sharda; Giulia Schiroli; Karin Gustafsson; Lingli He; Michael Mazzola; Sam Keyes; Anna Kiem; Eve Crompton; Yanxin Xu; Sovannarith Korm; Zhixun Dou; Charles Vidoudez; Peter G. Miller; Nick van Gastel; Timothy A. Graubert; David T. Scadden
Integrative cytogenetic and molecular studies unmask chromosomal mimicry in hematologic malignancies

整合细胞遗传学和分子学研究揭示了血液系统恶性肿瘤中的染色体拟态现象

BLOOD ADVANCES
IF7.1
2025-03-111
OA
Zhao, Melissa; Ryall, Scott; Brody, Samuel J.; Harris, Amyah C.; Cabral, Kristin; Brownstein, Catherine; Kim, Jaeseung C.; Smith, Adam C.; Dal Cin, Paola; Narayan, Rupa; Sikkink, Kristin; Schmitt, Anthony; Griffin, Gabriel K.; Hobbs, Gabriela S.; Fathi, Amir T.; Sait, Sheila N. J.; Iafrate, Anthony J.; Aster, Jon C.; Graubert, Timothy A.; Nardi, Valentina; Dubuc, Adrian M.
TRK Protein Expression in TP53 Altered Acute Erythroid Leukemia

TRK蛋白在TP53改变的急性红系白血病中的表达

BLOOD
IF23.1
2024-11-050
PRE
Narayan, Rupa; Swords, Ronan T.; Amrein, Philip C.; Brunner, Andrew M.; Hobbs, Gabriela S.; Hock, Hanno; Lee, Michelle Hyunju; Graubert, Timothy Aaron; Fathi, Amir T.; Hasserjian, Robert P.; Nardi, Valentina
R-Loop Accumulation in Spliceosome Mutant Leukemias Confers Sensitivity to PARP1 Inhibition by Triggering Transcription-Replication Conflicts
CANCER RESEARCH
IF16.6
2023-11-156
OA
Liu, Zhiyan Silvia; Sinha, Sayantani; Bannister, Maxwell; Song, Axia; Arriaga-Gomez, Erica; Mckeeken, Alexander J.; Bonner, Elizabeth A.; Hanson, Benjamin K.; Sarchi, Martina; Takashima, Kouhei; Zong, Dawei; Corral, Victor M.; Nguyen, Evan; Yoo, Jennifer; Chiraphapphaiboon, Wannasiri; Leibson, Cassandra; Mcmahon, Matthew C.; Rai, Sumit; Swisher, Elizabeth M.; Sachs, Zohar; Chatla, Srinivas; Stirewalt, Derek L.; Deeg, H. Joachim; Skorski, Tomasz; Papapetrou, Eirini P.; Walter, Matthew J.; Graubert, Timothy A.; Doulatov, Sergei; Lee, Stanley C.; Nguyen, Hai Dang
PARP inhibitors preferentially sensitize splicing factor mutant myeloid neoplasms
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Nguyen, Dang Hai; Sinha, Sayantani; Liu, Zhiyan Silvia; Bannister, Maxwell Henry; Arriaga-Gomez, Erica; Song, Axia; Zong, Dawei; Sarchi, Martina; Corral, Victor; Chiraphapphaiboon, Wannasiri; Yoo, Jennifer; McMahon, Matthew; Leibson, Cassandra; Stirewalt, Derek L.; Deeg, H. Joachim; Rai, Sumit; Walter, Matthew; Graubert, Timothy A.; Doulatov, Sergei; Lee, Stanley C.
Long: molecular tracking of CML with bilineal inv(16) myeloid and del(9) lymphoid blast crisis and durable response to CD19-directed CAR-T therapy
LEUKEMIA
IF13.4
2020-07-163
PREAI
Venkataraman, Vinayak; Casey, Keagan S.; Onozato, Maristela; Dal Cin, Paola; Nardi, Valentina; Amrein, Philip C.; Bergeron, Meghan K.; Brunner, Andrew M.; Fathi, Amir T.; Foster, Julia E.; Moran, Jenna; Graubert, Timothy A.; Hock, Hanno; Hunnewell, Chrisa; Frigault, Matthew J.; McAfee, Steven; Hobbs, Gabriela S.
Alisertib plus induction chemotherapy in previously untreated patients with high-risk, acute myeloid leukaemia: a single-arm, phase 2 trial
LANCET HAEMATOLOGY
IF17.7
2020-02-0126
OAAI
Brunner, Andrew M.; Blonquist, Traci M.; DeAngelo, Daniel J.; McMasters, Malgorzata; Fell, Geoffrey; Hermance, Nicole M.; Winer, Eric S.; Lindsley, R. Coleman; Hobbs, Gabriela S.; Amrein, Philip C.; Hock, Hanno R.; Steensma, David P.; Garcia, Jacqueline S.; Luskin, Marlise R.; Stone, Richard M.; Ballen, Karen K.; Rosenblatt, Jacalyn; Avigan, David; Nahas, Myrna R.; Mendez, Lourdes M.; McAfee, Steven L.; Moran, Jenna A.; Bergeron, Meghan; Foster, Julia; Bertoli, Christina; Manning, Amity L.; McGregor, Kristin L.; Fishman, Kaitlyn M.; Kuo, Frank C.; Baltay, Michele T.; Macrae, Molly; Burke, Meghan; Behnan, Tanya; Wey, Margaret C.; Som, Tina T.; Ramos, Aura Y.; Rae, Jessica; Story, Jennifer Lombardi; Nelson, Nicole; Logan, Emma; Connolly, Christine; Neuberg, Donna S.; Chen, Yi-Bin; Graubert, Timothy A.; Fathi, Amir T.
A phase 1 study of the antibody-drug conjugate brentuximab vedotin with re-induction chemotherapy in patients with CD30-expressing relapsed/refractory acute myeloid leukemia
CANCER
IF5.1
2019-12-2016
OAAI
Narayan, Rupa; Blonquist, Traci M.; Emadi, Ashkan; Hasserjian, Robert P.; Burke, Meghan; Lescinskas, Christopher; Neuberg, Donna S.; Brunner, Andrew M.; Hobbs, Gabriela; Hock, Hanno; McAfee, Steven L.; Chen, Yi-Bin; Attar, Eyal; Graubert, Timothy A.; Bertoli, Christina; Moran, Jenna A.; Bergeron, Meghan K.; Foster, Julia E.; Ramos, Aura Y.; Som, Tina T.; Vartanian, Megan K.; Story, Jennifer L.; McGregor, Kristin; Macrae, Molly; Behnan, Tanya; Wey, Margaret C.; Rae, Jessica; Preffer, Frederic, I; Lesho, Patricia; Duong, Vu H.; Mann, Mason L.; Ballen, Karen K.; Connolly, Christine; Amrein, Philip C.; Fathi, Amir T.
TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups
LEUKEMIA
IF13.4
2019-01-11177
OAAI
Haase, Detlef; Stevenson, Kristen E.; Neuberg, Donna; Maciejewski, Jaroslaw P.; Nazha, Aziz; Sekeres, Mikkael A.; Ebert, Benjamin L.; Garcia-Manero, Guillermo; Haferlach, Claudia; Haferlach, Torsten; Kern, Wolfgang; Ogawa, Seishi; Nagata, Yasunobu; Yoshida, Kenichi; Graubert, Timothy A.; Walter, Matthew J.; List, Alan F.; Komrokji, Rami S.; Padron, Eric; Sallman, David; Papaemmanuil, Elli; Campbell, Peter J.; Savona, Michael R.; Seegmiller, Adam; Ades, Lionel; Fenaux, Pierre; Shih, Lee-Yung; Bowen, David; Groves, Michael J.; Tauro, Sudhir; Fontenay, Michaela; Kosmider, Olivier; Bar-Natan, Michal; Steensma, David; Stone, Richard; Heuser, Michael; Thol, Felicitas; Cazzola, Mario; Malcovati, Luca; Karsan, Aly; Ganster, Christina; Hellstrom-Lindberg, Eva; Boultwood, Jacqueline; Pellagatti, Andrea; Santini, Valeria; Quek, Lynn; Vyas, Paresh; Tuechler, Heinz; Greenberg, Peter L.; Bejar, Rafael
Isocitrate dehydrogenase 1 and 2 mutations, 2-hydroxyglutarate levels, and response to standard chemotherapy for patients with newly diagnosed acute myeloid leukemia
CANCER
IF5.1
2018-11-1326
OAAI
Brunner, Andrew M.; Neuberg, Donna S.; Wander, Seth A.; Sadrzadeh, Hossein; Ballen, Karen K.; Amrein, Philip C.; Attar, Eyal; Hobbs, Gabriela S.; Chen, Yi-Bin; Perry, Ashley; Connolly, Christine; Joseph, Christelle; Burke, Meghan; Ramos, Aura; Galinsky, Ilene; Yen, Katharine; Yang, Hua; Straley, Kimberly; Agresta, Sam; Adamia, Sophia; Borger, Darrell R.; Iafrate, Anthony; Graubert, Timothy A.; Stone, Richard M.; Fathi, Amir T.
Mutation Clearance after Transplantation for Myelodysplastic Syndrome
NEW ENGLAND JOURNAL OF MEDICINE
IF78.5
2018-09-1398
OAAI
Duncavage, E. J.; Jacoby, M. A.; Chang, G. S.; Miller, C. A.; Edwin, N.; Shao, J.; Elliott, K.; Robinson, J.; Abel, H.; Fulton, R. S.; Fronick, C. C.; O'Laughlin, M.; Heath, S. E.; Brendel, K.; Saba, R.; Wartman, L. D.; Christopher, M. J.; Pusic, I.; Welch, J. S.; Uy, G. L.; Link, D. C.; DiPersio, J. F.; Westervelt, P.; Ley, T. J.; Trinkaus, K.; Graubert, T. A.; Walter, M. J.
Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential
NATURE COMMUNICATIONS
IF15.7
2018-01-31155
OAAI
Wong, Terrence N.; Miller, Christopher A.; Jotte, Matthew R. M.; Bagegni, Nusayba; Baty, Jack D.; Schmidt, Amy P.; Cashen, Amanda F.; Duncavage, Eric J.; Helton, Nichole M.; Fiala, Mark; Fulton, Robert S.; Heath, Sharon E.; Janke, Megan; Luber, Kierstin; Westervelt, Peter; Vij, Ravi; DiPersio, John F.; Welch, John S.; Graubert, Timothy A.; Walter, Matthew J.; Ley, Timothy J.; Link, Daniel C.

研究方向

暂未获取到该数据
M
Matthew J. Walter
H 指数:55论文数:430被引数:2.8万
T
Timothy J. Ley
H 指数:116论文数:538被引数:8.7万
J
John F. DiPersio
H 指数:126论文数:1,370被引数:9.5万
R
Robert S. Fulton
H 指数:154论文数:584被引数:21.6万
R
Richard K. Wilson
H 指数:189论文数:682被引数:24.5万
D
Daniel C. Link
H 指数:86论文数:815被引数:3.4万
E
Elaine R. Mardis
H 指数:197论文数:1,691被引数:34.1万
P
Peter Westervelt
H 指数:90论文数:535被引数:6.2万
C
Christopher A. Miller
H 指数:96论文数:552被引数:7.9万
J
John S. Welch
H 指数:46论文数:313被引数:2.3万