David A. Davis - Publications, H-index & Citations

David A. Davis

National Cancer Institute

51H指数

256论文数

1.3W被引数

收录论文 88

发表时间

Novel Cereblon-Binding Immunomodulators Have Increased Potency Against Gammaherpesvirus- Associated Lymphomas In Vitro 新型cereblon结合免疫调节剂在体外对伽马疱疹病毒相关淋巴瘤具有增强的活性

Journal of Medical Virology

IF4.6

2025-08-06

OAAI

Prabha Shrestha; Emma N. Treco; David A. Davis; Robert Yarchoan

The elevated expression of ORF75, a KSHV lytic gene, in Kaposi sarcoma lesions is driven by a GC-rich DNA cis element in its promoter region ORF75基因，一种KSHV裂解基因，其在卡波西肉瘤病灶中的高表达是由其启动子区域中的GC富集DNA顺式元件驱动的。

PLOS PATHOGENS

IF4.9

2025-03-17

OAAI

Nair, Ashwin; Davis, David A.; Warner, Andrew; Karim, Baktiar; Ramaswami, Ramya; Yarchoan, Robert

Discovery of a nasal spray steroid, tixocortol, as an inhibitor of SARS-CoV-2 main protease and viral replication

RSC MEDICINAL CHEMISTRY

IF3.6

2024-01-01

PREAI

Davis, David A.; Nair, Ashwin; Astter, Yana; Treco, Emma; Peyser, Brian; Gussio, Rick; Nguyen, Tam; Eaton, Brett; Postnikova, Elena; Murphy, Michael; Shrestha, Prabha; Bulut, Haydar; Hattorri, Shin-Ichiro; Mitsuya, Hiroaki; Yarchoan, Robert

Hypoxia and hypoxia-inducible factors in Kaposi sarcoma-associated herpesvirus infection and disease pathogenesis

JOURNAL OF MEDICAL VIROLOGY

IF4.6

2023-09-04

OAAI

Davis, David A.; Shrestha, Prabha; Yarchoan, Robert

Mechanism and therapeutic implications of pomalidomide-induced immune surface marker upregulation in EBV-positive lymphomas

SCIENTIFIC REPORTS

IF3.9

2023-07-18

OAAI

Jaeger, Hannah K.; Davis, David A.; Nair, Ashwin; Shrestha, Prabha; Stream, Alexandra; Yaparla, Amulya; Yarchoan, Robert

GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants

SCIENCE ADVANCES

IF12.5

2023-07-14

OAAI

Aoki, Manabu; Aoki-Ogata, Hiromi; Bulut, Haydar; Hayashi, Hironori; Takamune, Nobutoki; Kishimoto, Naoki; Tanaka, Hiroki; Higashi-Kuwata, Nobuyo; Hattori, Shin-ichiro; Das, Debananda; Rao, Kalapala Venkateswara; Iwama, Kazuya; Davis, David A.; Hasegawa, Kazuya; Murayama, Kazutaka; Yarchoan, Robert; Ghosh, Arun K.; Pau, Alice K.; Machida, Shinichi; Misumi, Shogo; Mitsuya, Hiroaki

Malignancies in People with HIV: Successes and Challenges at the Intersection of Virology, Immunology, and Oncology

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Yarchoan, Robert; Lurain, Kathryn; Ramaswami, Ramya; Davis, David A.; Shrestha, Prabha

Daratumumab induces cell-mediated cytotoxicity of primary effusion lymphoma and is active against refractory disease

ONCOIMMUNOLOGY

IF6.3

2023-01-07

OAAI

Shrestha, Prabha; Astter, Yana; Davis, David A.; Zhou, Ting; Yuan, Constance M. M.; Ramaswami, Ramya; Wang, Hao-Wei; Lurain, Kathryn; Yarchoan, Robert

Regulation of Retroviral and SARS-CoV-2 Protease Dimerization and Activity through Reversible Oxidation

ANTIOXIDANTS

IF6.6

2022-10-18

OAAI

Davis, David A.; Bulut, Haydar; Shrestha, Prabha; Mitsuya, Hiroaki; Yarchoan, Robert

Transient Viral Activation in Human T Cell Leukemia Virus Type 1-Infected Macaques Treated With Pomalidomide

FRONTIERS IN MEDICINE

IF3

2022-05-05

OAAI

Gutowska, Anna; McKinnon, Katherine; Sarkis, Sarkis; Doster, Melvin N.; Bissa, Massimiliano; Moles, Ramona; Stamos, James D.; Rahman, Mohammad Arif; Washington-Parks, Robyn; Davis, David; Yarchoan, Robert; Franchini, Genoveffa; Pise-Masison, Cynthia A.

Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300

MBIO

IF4.7

2021-08-31

OAAI

Davis, David A.; Bulut, Haydar; Shrestha, Prabha; Yaparla, Amulya; Jaeger, Hannah K.; Hattori, Shin-ichiro; Wingfield, Paul T.; Mieyal, John J.; Mitsuya, Hiroaki; Yarchoan, Robert

Identification of a novel long-acting 4′-modified nucleoside reverse transcriptase inhibitor against HBV

JOURNAL OF HEPATOLOGY

IF33

2021-05-01

OAAI

Higashi-Kuwata, Nobuyo; Hayashi, Sanae; Kumamoto, Hiroki; Ogata-Aoki, Hiromi; Das, Debananda; Venzon, David; Hattori, Shin-ichiro; Bulut, Haydar; Hashimoto, Mai; Otagiri, Masaki; Takamune, Nobutoki; Kishimoto, Naoki; Davis, David A.; Misumi, Shogo; Kakuni, Masakazu; Tanaka, Yasuhito; Mitsuya, Hiroaki

A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication

NATURE COMMUNICATIONS

IF15.7

2021-01-28

136

OAAI

Hattori, Shin-ichiro; Higashi-Kuwata, Nobuyo; Hayashi, Hironori; Allu, Srinivasa Rao; Raghavaiah, Jakka; Bulut, Haydar; Das, Debananda; Anson, Brandon J.; Lendy, Emma K.; Takamatsu, Yuki; Takamune, Nobutoki; Kishimoto, Naoki; Murayama, Kazutaka; Hasegawa, Kazuya; Li, Mi; Davis, David A.; Kodama, Eiichi N.; Yarchoan, Robert; Wlodawer, Alexander; Misumi, Shogo; Mesecar, Andrew D.; Ghosh, Arun K.; Mitsuya, Hiroaki

Pomalidomide restores immune recognition of primary effusion lymphoma through upregulation of ICAM-1 and B7-2

PLOS PATHOGENS

IF4.9

2021-01-07

OAAI

Shrestha, Prabha; Davis, David A.; Jaeger, Hannah K.; Stream, Alexandra; Aisabor, Ashley, I; Yarchoan, Robert

GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection GRL-0920，一种吲哚氯吡啶基酯，完全阻断SARS-CoV-2感染

MBIO

IF4.7

2020-08-25

OAAI

Hattori, Shin-ichiro; Higshi-Kuwata, Nobuyo; Raghavaiah, Jakka; Das, Debananda; Bulut, Haydar; Davis, David A.; Takamatsu, Yuki; Matsuda, Kouki; Takamune, Nobutoki; Kishimoto, Naoki; Okamura, Tadashi; Misumi, Shogo; Yarchoan, Robert; Maeda, Kenji; Ghosh, Arun K.; Mitsuya, Hiroaki

Single atom changes in newly synthesized HIV protease inhibitors reveal structural basis for extreme affinity, high genetic barrier, and adaptation to the HIV protease plasticity

SCIENTIFIC REPORTS

IF3.9

2020-06-30

OAAI

Bulut, Haydar; Hattori, Shin-ichiro; Aoki-Ogata, Hiromi; Hayashi, Hironori; Das, Debananda; Aoki, Manabu; Davis, David A.; Rao, Kalapala Venkateswara; Nyalapatla, Prasanth R.; Ghosh, Arun K.; Mitsuya, Hiroaki

Induction of Kaposi's Sarcoma-Associated Herpesvirus-Encoded Thymidine Kinase (ORF21) by X-Box Binding Protein 1

JOURNAL OF VIROLOGY

IF3.8

2020-02-14

OAAI

Wang, Victoria; Davis, David A.; Deleage, Claire; Brands, Catherine; Choi, Hong S.; Haque, Muzammel; Yarchoan, Robert

Pomalidomide increases immune surface marker expression and immune recognition of oncovirus-infected cells

ONCOIMMUNOLOGY

IF6.3

2018-12-05

OAAI

Davis, David A.; Shrestha, Prabha; Aisabor, Ashley I.; Stream, Alexandra; Galli, Veronica; Pise-Masison, Cynthia A.; Tagawa, Takanobu; Ziegelbauer, Joseph M.; Franchini, Genoveffa; Yarchoan, Robert

Translating evidence into practice: Lessons for CPD

MEDICAL TEACHER

IF4.4

2018-07-23

PREAI

Davis, David A. (Dave); McMahon, Graham T.

PTEN loss in the fallopian tube induces hyperplasia and ovarian tumor formation

ONCOGENE

IF7.3

2018-01-25

OAAI

Russo, Angela; Czarnecki, Austin A.; Dean, Matthew; Modi, Dimple A.; Lantvit, Daniel D.; Hardy, Laura; Baligod, Seth; Davis, David A.; Wei, Jian-Jun; Burdette, Joanna E.

研究方向