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D

Don L. Siegel

University of Pennsylvania
H指数:42
被引数:6,689

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Publisher Correction: Decade-long persistence of CD19 CAR T cells in B cell lymphomas

出版更正：CD19 CAR T细胞在B细胞淋巴瘤中的十年持久性

Nature Medicine
IF50
2026-08-260
OAAI
Luca Paruzzo; Emeline R. Chong; Elise A. Chong; Zhixuan Zheng; Puneeth Guruprasad; Daniel J. Landsburg; Sunita D. Nasta; Federico Stella; Ranjani Ramasubramanian; Vitor B. de Souza; Mohannad H. Alkhatib; Matthew Ho; Antonio Imparato; Gregory M. Chen; Don L. Siegel; Gabriela Plesa; Anlan Dai; Shane Mackey; Priyamvada Das; Peter Michener; Julie Jadlowsky; Frederic D. Bushman; Vrutti Patel; Alberto Carturan; Ellen B. Napier; Vanessa E. Gonzalez; Danuta Jarocha; Rong Xu; Bruce L. Levine; Patrizia Porazzi; Noelle Frey; David L. Porter; Jakub Svoboda; Joseph A. Fraietta; Carl H. June; Stephen J. Schuster; Marco Ruella
Decade-long persistence of CD19 CAR T cells in B cell lymphomas

CD19 CAR T细胞在B细胞淋巴瘤中的十年持续性

Nature Medicine
IF50
2026-08-100
OA
Luca Paruzzo; Emeline R. Chong; Elise A. Chong; Zhixuan Zheng; Puneeth Guruprasad; Daniel J. Landsburg; Sunita D. Nasta; Federico Stella; Ranjani Ramasubramanian; Vitor B. de Souza; Mohannad H. Alkhatib; Matthew Ho; Antonio Imparato; Gregory M. Chen; Don L. Siegel; Gabriela Plesa; Anlan Dai; Shane Mackey; Priyamvada Das; Peter Michener; Julie Jadlowsky; Frederic D. Bushman; Vrutti Patel; Alberto Carturan; Ellen B. Napier; Vanessa E. Gonzalez; Danuta Jarocha; Rong Xu; Bruce L. Levine; Patrizia Porazzi; Noelle Frey; David L. Porter; Jakub Svoboda; Joseph A. Fraietta; Carl H. June; Stephen J. Schuster; Marco Ruella
Predictive biomarkers of response to chimeric antigen receptor (CAR) T-cell therapy for pan-haematologic cancer

泛血液学癌症对嵌合抗原受体 (CAR) T细胞治疗反应的预测生物标志物

Nature Biomedical Engineering
IF26.6
2026-03-090
PRE
Gregory M. Chen; Ankita Jain; David T. Gering; Javier Satulovsky; Sarbani Datta; Peng Lai; Jayashree Karar; Vanessa E. Gonzalez; Kathleen Alexander; Anne Chew; Julie K. Jadlowsky; Marco Ruella; Luca Paruzzo; Kevin R. Amses; Andrew J. Rech; Edward A. Stadtmauer; Noelle V. Frey; Elizabeth O. Hexner; David L. Porter; Adam D. Cohen; Saar I. Gill; Alfred L. Garfall; Stephen J. Schuster; Kelvin C. Mo; Samantha I. Liang; Marko Spasic; Bruce L. Levine; Don L. Siegel; Angel Ramírez-Fernández; Christopher R. Cabanski; EnJun Yang; Crystal L. Mackall; Frederic D. Bushman; Zinaida Good; E. John Wherry; Carl H. June; Joseph A. Fraietta
CCR5-targeted allogeneic gamma–delta CD19 chimeric antigen receptor T cells for HIV-associated B cell-malignancy immunotherapy

CCR5靶向的异基因γ-δ CD19嵌合抗原受体T细胞用于HIV相关B细胞恶性免疫治疗

Nature Biomedical Engineering
IF26.6
2025-10-210
PRE
Ángel Ramírez-Fernández; Alexander J. Dimitri; Fang Chen; Robert Bartoszek; Gregory M. Chen; Laura Córdoba-Espejo; Yuqi Zhou; Yun-hsin Tang; Chien-Ting Lin; Reyes Acosta; John Scholler; Guido Ghilardi; Patrizia Porazzi; Mireia Pellicer; Núria Profitós-Pelejà; Stefan K. Barta; Anne Chew; Julie K. Jadlowsky; Vanessa E. Gonzalez; Donald L. Siegel; Bruce L. Levine; Gaël Roué; Marco Ruella; Michael T. Lotze; Carl H. June; James L. Riley; Joseph A. Fraietta
Intracerebroventricular bivalent CAR T cells targeting EGFR and IL-13Rα2 in recurrent glioblastoma: a phase 1 trial

Bagley SJ, Desai AS, Fraietta JA, Silverbush D, Chafamo D, Freeburg NF, et al. 静脉内双价CAR T细胞靶向EGFR和IL-13Rα2治疗复发性胶质母细胞瘤：一项1期临床试验。Nat Med. (2025). doi: 10.1038/s41591-025-03745-0

Nature Medicine
IF50
2025-06-010
PRE
Stephen J. Bagley; Arati S. Desai; Joseph A. Fraietta; Dana Silverbush; Daniel Chafamo; Nelson F. Freeburg; Gayathri Konanur Gopikrishna; Andrew J. Rech; Ali Nabavizadeh; Linda J. Bagley; Jungmin Park; Danuta Jarocha; Rene Martins; Nicolas Sarmiento; Eileen Maloney; Lester Lledo; Carly Stein; Amy Marshall; Rachel M. Leskowitz; Julie K. Jadlowsky; Shane Mackey; Shannon Christensen; Bike Su Oner; Gabriela Plesa; Andrea Brennan; Vanessa Gonzalez; Fang Chen; David Barrett; Robert Colbourn; MacLean P. Nasrallah; Zissimos Mourelatos; Wei-Ting Hwang; Cecile Alanio; Donald L. Siegel; Carl H. June; Elizabeth O. Hexner; Zev A. Binder; Donald M. O’Rourke
Cytokine-mediated CAR T therapy resistance in AML

细胞因子介导的AML car-t治疗耐药

NATURE MEDICINE
IF50
2024-09-272
PRE
Bhagwat, Anand S.; Torres, Leonel; Shestova, Olga; Shestov, Maksim; Mellors, Patrick W.; Fisher, Han R.; Farooki, Saamia N.; Frost, Benjamin F.; Loken, Michael R.; Gaymon, Avery L.; Frazee, Diane; Rogal, Walter; Frey, Noelle; Hexner, Elizabeth O.; Luger, Selina M.; Loren, Alison W.; Martin, Mary Ellen; Mccurdy, Shannon R.; Perl, Alexander E.; Stadtmauer, Edward A.; Brogdon, Jennifer L.; Fraietta, Joseph A.; Hwang, Wei-Ting; Siegel, Don L.; Plesa, Gabriela; Aplenc, Richard; Porter, David L.; June, Carl H.; Gill, Saar I.
CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication (vol 131, e144486, 2021)
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-05-011
OAAI
Tebas, Pablo; Jadlowsky, Julie K.; Shaw, Pamela A.; Tian, Lifeng; Esparza, Erin; Brennan, Andrea L.; Kim, Sukyung; Naing, Soe Yu; Richardson, Max W.; Vogel, Ashley N.; Maldini, Colby R.; Kong, Hong; Liu, Xiaojun; Lacey, Simon F.; Bauer, Anya M.; Mampe, Felicity; Richman, Lee P.; Lee, Gary; Ando, Dale; Levine, Bruce L.; Porter, David L.; Zhao, Yangbing; Siegel, Don L.; Bar, Katharine J.; June, Carl H.; Riley, James L.
Anti-BCMA/CD19 CAR T Cells with Early Immunomodulatory Maintenance for Multiple Myeloma Responding to Initial or Later-Line Therapy

抗BCMA/CD19 CAR T细胞与多发性骨髓瘤的早期免疫调节维持对初始或后续治疗有反应

BLOOD CANCER DISCOVERY
IF11.5
2022-11-2144
OAAI
Garfall, Alfred L.; Cohen, Adam D.; Susanibar-Adaniya, Sandra P.; Hwang, Wei-Ting; Vogl, Dan T.; Waxman, Adam J.; Lacey, Simon F.; Gonzalez, Vanessa E.; Fraietta, Joseph A.; Gupta, Minnal; Kulikovskaya, Irina; Tian, Lifeng; Chen, Fang; Koterba, Natalka; Bartoszek, Robert L.; Patchin, Margaret; Xu, Rong; Plesa, Gabriela; Siegel, Don L.; Brennan, Andrea; Nelson, Anne Marie; Ferthio, Regina; Cosey, Angela; Shea, Kim-Marie; Leskowitz, Rachel; Four, Megan; Wilson, Wesley, V; Miao, Fei; Lancaster, Eric; Carreno, Beatriz M.; Linette, Gerald P.; Hexner, Elizabeth O.; Young, Regina M.; Bu, Dexiu; Mansfield, Keith G.; Brogdon, Jennifer L.; June, Carl H.; Milone, Michael C.; Stadtmauer, Edward A.
Nucleocapsid-specific antibody function is associated with therapeutic benefits from COVID-19 convalescent plasma therapy
CELL REPORTS MEDICINE
IF10.6
2022-11-0114
OAAI
Herman, Jonathan D.; Wang, Chuangqi; Burke, John Stephen; Zur, Yonatan; Compere, Hacheming; Kang, Jaewon; Macvicar, Ryan; Taylor, Sabian; Shin, Sally; Frank, Ian; Siegel, Don; Tebas, Pablo; Choi, Grace H.; Shaw, Pamela A.; Yoon, Hyunah; Pirofski, Liise-anne; Julg, Boris D.; Bar, Katharine J.; Lauffenburger, Douglas; Alter, Galit
Decade-long leukaemia remissions with persistence of CD4+ CAR T cells

长达十年的白血病缓解与CD4 car-t细胞的持久性

Nature
IF48.5
2022-02-020
PRE
J. Joseph Melenhorst; Gregory M. Chen; Meng Wang; David L. Porter; Changya Chen; McKensie A. Collins; Peng Gao; Shovik Bandyopadhyay; Hongxing Sun; Ziran Zhao; Stefan Lundh; Iulian Pruteanu-Malinici; Christopher L. Nobles; Sayantan Maji; Noelle V. Frey; Saar I. Gill; Alison W. Loren; Lifeng Tian; Irina Kulikovskaya; Minnal Gupta; David E. Ambrose; Megan M. Davis; Joseph A. Fraietta; Jennifer L. Brogdon; Regina M. Young; Anne Chew; Bruce L. Levine; Donald L. Siegel; Cécile Alanio; E. John Wherry; Frederic D. Bushman; Simon F. Lacey; Kai Tan; Carl H. June

研究方向

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C
Carl H. June
H 指数:177论文数:1,428被引数:14.4万
B
Bruce L. Levine
H 指数:102论文数:550被引数:6.6万
J
John R. Stanley
H 指数:78论文数:287被引数:2.1万
J
Joseph A. Fraietta
H 指数:45论文数:359被引数:1.5万
E
Edward A. Stadtmauer
H 指数:88论文数:628被引数:3.6万
J
Julie K. Jadlowsky
H 指数:19论文数:68被引数:3,776
S
Simon F. Lacey
H 指数:75论文数:382被引数:3.8万
A
Alfred L. Garfall
H 指数:41论文数:312被引数:1.1万
V
Vladimir R. Muzykantov
H 指数:79论文数:372被引数:2.0万
G
Gabriela Plesa
H 指数:40论文数:245被引数:1.3万