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Alexander Marson

Gladstone-UCSF Institute of Genomic Immunology

59H指数
223论文数
2.0W被引数
收录论文 77
发表时间
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Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits在全基因组规模扰动测序中，利用原发性人类CD4+ T细胞绘制T细胞程序和人类免疫性状的特定背景调节因子图谱
errCell
IF42.5
err2026-08-28
err0
errOAAI
errRonghui Zhu; Emma Dann; Jun Yan; Justine Reyes Retana; Ryunosuke Goto; Reese C. Guitche; Lillian Brixi; Mineto Ota; Austin Hartman; Theodore L. Roth; Ansuman T. Satpathy; Jonathan K. Pritchard; Alexander Marson
err分享
err收藏
In vivo genome-wide CRISPR screens of human T cells in solid tumours实体瘤中人类T细胞的体内全基因组CRISPR筛选
errNature
IF48.5
err2026-08-12
err0
PREAI
errQi Liu; Peixin Amy Chen; Esha Urs; Shimin Zhang; Maya M. Arce; Charlotte H. Wang; Jun Yan; Vinh Q. Nguyen; Zhongmei Li; Jin Seo; Nupura Kale; Fanglue Peng; Yikai Luo; Laine Goudy; Taylor N. LaFlam; Haixia Zhong; Chandrima Modak; Emma Dann; Jae Hyung Jung; Amanda Kirane; Allison Betof Warner; Boi Bryant Quach; Zinaida Good; Brian R. Shy; Eric Shifrut; Sagar P. Bapat; Greg M. Allen; Justin Eyquem; Katherine Fuh; Stacie E. Dodgson; Jason G. Cyster; Alexander Marson; Julia Carnevale
err分享
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Harmonizing standards and resources for the medical genome调和医学基因组的标准与资源
errNature
IF48.5
err2026-07-01
err0
PREAI
errEuan A. Ashley; Ash A. Alizadeh; Hanae Armitage; Ami S. Bhatt; Yair Blumenfeld; Andrew Carroll; R. Martin Chavez; Petros Giannikopoulos; Megan E. Grove; Meghan C. Halley; Kiran Khush; Niall J. Lennon; Samantha Maragh; Alexander Marson; Benedict Paten; Adam M. Phillippy; Matthew H. Porteus; Heidi L. Rehm; Bradley R. Ringeisen; Julia Salzman; Valerie A. Schneider; Fritz J. Sedlazeck; Lars M. Steinmetz; Fyodor D. Urnov; Stacia K. Wyman; Justin M. Zook; Lloyd B. Minor; Jennifer A. Doudna
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err收藏
Causal modelling of gene effects from regulators to programs to traits从监管者到程序到性状的基因效应的因果模型
errNature
IF48.5
err2025-12-10
err0
errOAAI
errMineto Ota; Jeffrey P. Spence; Tony Zeng; Emma Dann; Nikhil Milind; Alexander Marson; Jonathan K. Pritchard
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Site-specific DNA insertion into the human genome with engineered recombinases用工程重组酶将位点特异性DNA插入人类基因组
errNature Biotechnology
IF41.7
err2025-11-06
err0
errOAAI
errAlison Fanton; Liam J. Bartie; Juliana Q. Martins; Vincent Q. Tran; Laine Goudy; Courtney Kernick; Matthew G. Durrant; Jingyi Wei; Zev Armour-Garb; April Pawluk; Silvana Konermann; Alexander Marson; Luke A. Gilbert; Theodore L. Roth; Patrick D. Hsu
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Mapping the extracellular molecular architecture of the pAg-signaling complex with α-Butyrophilin antibodies
errSCIENTIFIC REPORTS
IF3.9
err2025-04-09
err0
errOAAI
errRamesh, Amrita; Roy, Sobhan; Slezak, Tomasz; Fuller, James; Graves, Hortencia; Mamedov, Murad R.; Marson, Alexander; Kossiakoff, Anthony A.; Adams, Erin J.
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Gene regulatory network inference from CRISPR perturbations in primary CD4+ T cells elucidates the genomic basis of immune disease原代CD4 T细胞中CRISPR扰动的基因调控网络推断阐明了免疫疾病的基因组基础
errCELL GENOMICS
IF9
err2024-11-01
err0
errOAAI
errWeinstock, Joshua S.; Arce, Maya M.; Freimer, Jacob W.; Ota, Mineto; Marson, Alexander; Battle, Alexis; Pritchard, Jonathan K.
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Phenotypic profiling of human induced regulatory T cells at early differentiation: insights into distinct immunosuppressive potential
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2024-09-12
err0
errOAAI
errKattelus, Roosa; Starskaia, Inna; Linden, Markus; Batkulwar, Kedar; Pietila, Sami; Moulder, Robert; Marson, Alexander; Rasool, Omid; Suomi, Tomi; Elo, Laura L.; Lahesmaa, Riitta; Buchacher, Tanja
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Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4+regulatory T cells by regulating IL2RA长链非编码RNA LIRIL2R通过调节IL2RA调节人CD4调节性T细胞的FOXP3水平和抑制功能
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-05-28
err0
errOAAI
errAndrabi, Syed Bilal Ahmad; Kalim, Ubaid Ullah; Palani, Senthil; Khan, Mohd Moin; Khan, Meraj Hasan; Fagersund, Jimmy; Orpana, Julius; Paulin, Niklas; Batkulwar, Kedar; Junttila, Sini; Buchacher, Tanja; Gronroos, Toni; Toikka, Lea; Ammunet, Tea; Sen, Partho; Oresic, Matej; Kumpulainen, Venla; Tuomisto, Johanna E. E.; Sinha, Rahul; Marson, Alexander; Rasool, Omid; Elo, Laura L.; Lahesmaa, Riitta
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Bidirectional epigenetic editing reveals hierarchies in gene regulation
errNATURE BIOTECHNOLOGY
IF41.7
err2024-05-17
err2
errOAAI
errPacalin, Naomi M.; Steinhart, Zachary; Shi, Quanming; Belk, Julia A.; Dorovskyi, Dmytro; Kraft, Katerina; Parker, Kevin R.; Shy, Brian R.; Marson, Alexander; Chang, Howard Y.
err分享
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CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cellsE3泛素连接酶的CRISPR-Cas9筛选将TRAF2和UHRF1鉴定为原代人T细胞中HIV潜伏期的调节剂
errMBIO
IF4.7
err2024-04-10
err0
errOAAI
errRathore, Ujjwal; Haas, Paige; Kumar, Vigneshwari Easwar; Hiatt, Joseph; Haas, Kelsey M.; Bouhaddou, Mehdi; Swaney, Danielle L.; Stevenson, Erica; Zuliani-Alvarez, Lorena; McGregor, Michael J.; Turner-Groth, Autumn; Ochieng' Olwal, Charles; Bediako, Yaw; Braberg, Hannes; Soucheray, Margaret; Ott, Melanie; Eckhardt, Manon; Hultquist, Judd F.; Marson, Alexander; Kaake, Robyn M.; Krogan, Nevan J.
err分享
err收藏
Advancing T cell-based cancer therapy with single-cell technologies (vol 28, pg pages1761, 2022)
errNATURE MEDICINE
IF50
err2024-02-05
err0
errOAAI
errBucktrout, Samantha L.; Banovich, Nicholas E.; Butterfield, Lisa H.; Cimen-Bozkus, Cansu; Giles, Josephine R.; Good, Zinaida; Goodman, Daniel; Jonsson, Vanessa D.; Lareau, Caleb; Marson, Alexander; Maurer, Deena M.; Munson, Paul V.; Stubbington, Mike; Taylor, Sarah; Cutchin, Abbey
err分享
err收藏
The lncRNA Malat1 inhibits miR-15/16 to enhance cytotoxic T cell activation and memory cell formation
errELIFE
IF0
err2023-12-21
err9
errOAAI
errWheeler, Benjamin D.; Gagnon, John D.; Zhu, Wandi S.; Munoz-Sandoval, Priscila; Wong, Simon K.; Simeonov, Dimitre S.; Li, Zhongmei; Debarge, Rachel; Spitzer, Matthew H.; Marson, Alexander; Ansel, K. Mark
err分享
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PIM kinases regulate early human Th17 cell differentiation
errCELL REPORTS
IF6.9
err2023-12-01
err4
errOAAI
errBuchacher, Tanja; Shetty, Ankitha; Koskela, Saara A.; Smolander, Johannes; Kaukonen, Riina; Sousa, Antonio G. G.; Junttila, Sini; Laiho, Asta; Rundquist, Olof; Lonnberg, Tapio; Marson, Alexander; Rasool, Omid; L., Laura; Lahesmaa, Riitta
err分享
err收藏
HIC1 interacts with FOXP3 multi protein complex: Novel pleiotropic mechanisms to regulate human regulatory T cell differentiation and function
errIMMUNOLOGY LETTERS
IF2.8
err2023-11-01
err4
PREAI
errAndrabi, Syed Bilal Ahmad; Batkulwar, Kedar; Bhosale, Santosh D.; Moulder, Robert; Khan, Meraj Hasan; Buchacher, Tanja; Khan, Mohd Moin; Arnkil, Ilona; Rasool, Omid; Marson, Alexander; Kalim, Ubaid Ullah; Lahesmaa, Riitta
err分享
err收藏
CD25 recruits inhibitory phosphatases for feedback control of B-cell receptor signaling
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-05-01
err0
errOAAI
errSun, Ruifeng; Lee, Jaewoong; Robinson, Mark E.; Kume, Kohei; Cosgun, Kadriye Nehir; Chan, Lai N.; Leveille, Etienne; Geng, Huimin; Vykunta, Vivasvan; Shy, Brian; Marson, Alexander; Meffre, Eric; Muschen, Markus
err分享
err收藏
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2023-04-25
err46
errOAAI
errFoss, Dana V.; Muldoon, Joseph J.; Nguyen, David N.; Carr, Daniel; Sahu, Srishti U.; Hunsinger, John M.; Wyman, Stacia K.; Krishnappa, Netravathi; Mendonsa, Rima; Schanzer, Elaine V.; Shy, Brian R.; Vykunta, Vivasvan S.; Allain, Vincent; Li, Zhongmei; Marson, Alexander; Eyquem, Justin; Wilson, Ross C.
err分享
err收藏
A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function
errNATURE IMMUNOLOGY
IF27.6
err2023-03-13
err11
errOAAI
errLo, Wan-Lin; Kuhlmann, Miriam; Rizzuto, Gabrielle; Ekiz, H. Atakan; Kolawole, Elizabeth M.; Revelo, Monica P.; Andargachew, Rakieb; Li, Zhongmei; Tsai, Yuan-Li; Marson, Alexander; Evavold, Brian D.; Zehn, Dietmar; Weiss, Arthur
err分享
err收藏
Advancing T cell-based cancer therapy with single-cell technologies
errNATURE MEDICINE
IF50
err2022-09-20
err4
PREAI
errBucktrout, Samantha L.; Banovich, Nicholas E.; Butterfield, Lisa H.; Cimen-Bozkus, Cansu; Giles, Josephine R.; Good, Zinaida; Goodman, Daniel; Jonsson, Vanessa D.; Lareau, Caleb; Marson, Alexander; Maurer, Denna M.; Munson, Paul, V; Stubbington, Mike; Taylor, Sarah; Cutchin, Abbey
err分享
err收藏
High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails
errNATURE BIOTECHNOLOGY
IF41.7
err2022-08-25
err89
errOAAI
errShy, Brian R.; Vykunta, Vivasvan S.; Ha, Alvin; Talbot, Alexis; Roth, Theodore L.; Nguyen, David N.; Pfeifer, Wolfgang G.; Chen, Yan Yi; Blaeschke, Franziska; Shifrut, Eric; Vedova, Shane; Mamedov, Murad R.; Chung, Jing-Yi Jing; Li, Hong; Yu, Ruby; Wu, David; Wolf, Jeffrey; Martin, Thomas G.; Castro, Carlos E.; Ye, Lumeng; Esensten, Jonathan H.; Eyquem, Justin; Marson, Alexander
err分享
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研究方向

暂无研究方向
合作学者
合作期刊
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Eric S. Lander
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R
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A
Aviv Regev
H 指数: 208 · 论文数: 965
H
Howard Y. Chang
H 指数: 162 · 论文数: 737
B
Bruce D. Walker
H 指数: 160 · 论文数: 946
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