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K

Kilian Kleemann

University Hospital Bonn
H指数:8
被引数:873

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Lysosomal dysfunction drives a transcriptional and epigenetic signature found in disease-associated microglia in neurodegenerative diseases

溶酶体功能障碍驱动神经退行性疾病中疾病相关小胶质细胞的转录和表观遗传特征

Immunity
IF26.3
2026-08-030
PRE
Christopher D. Balak; Johannes C.M. Schlachetzki; Addison J. Lana; Elizabeth West; Christine Hong; Jordan DuGal; Yi Zhou; Benjamin Li; Nathanael J. Spann; Payam Saisan; Vishal Sarsani; Kilian L. Kleemann; Xiaoming Zhang; Martina P. Pasillas; Sydney O’Brien; Juliette A. Bokor; Philip L.S.M. Gordts; Oleg Butovsky; Beth Stevens; Fredrik Kamme
Author Correction: Disease-associated astrocyte epigenetic memory promotes CNS pathology

作者更正: 疾病相关星形胶质细胞表观遗传记忆促进CNS病理

Nature
IF48.5
2025-08-260
OA
Hong-Gyun Lee; Joseph M. Rone; Zhaorong Li; Camilo Faust Akl; Seung Won Shin; Joon-Hyuk Lee; Lucas E. Flausino; Florian Pernin; Chun-Cheih Chao; Kilian L. Kleemann; Lena Srun; Tomer Illouz; Federico Giovannoni; Marc Charabati; Liliana M. Sanmarco; Jessica E. Kenison; Gavin Piester; Stephanie E. J. Zandee; Jack P. Antel; Veit Rothhammer; Michael A. Wheeler; Alexandre Prat; Iain C. Clark; Francisco J. Quintana
Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity

辐射状胶质细胞整合素avb8调控细胞自主的小胶质细胞TGFβ1信号，该信号对于小胶质细胞表型维持是必需的。

NATURE COMMUNICATIONS
IF15.7
2025-03-221
OA
McKinsey, Gabriel L.; Santander, Nicolas; Zhang, Xiaoming; Kleemann, Kilian L.; Tran, Lauren; Katewa, Aditya; Conant, Kaylynn; Barraza, Matthew; Waddell, Kian; Lizama, Carlos O.; La Russa, Marie; Koo, Ji Hyun; Lee, Hyunji; Mukherjee, Dibyanti; Paidassi, Helena; Anton, E. S.; Atabai, Kamran; Sheppard, Dean; Butovsky, Oleg; Arnold, Thomas D.
Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease

性别依赖的APOE4中性粒细胞-小胶质细胞相互作用驱动阿尔茨海默病的认知障碍

NATURE MEDICINE
IF50
2024-07-035
PRE
Rosenzweig, Neta; Kleemann, Kilian L.; Rust, Thomas; Carpenter, Madison; Grucci, Madeline; Aronchik, Michael; Brouwer, Nieske; Valenbreder, Isabel; Cooper-Hohn, Joya; Iyer, Malvika; Krishnan, Rajesh K.; Sivanathan, Kisha N.; Brandao, Wesley; Yahya, Taha; Durao, Ana; Yin, Zhuoran; Chadarevian, Jean Paul; Properzi, Michael J.; Nowarski, Roni; Davtyan, Hayk; Weiner, Howard L.; Blurton-Jones, Mathew; Yang, Hyun-Sik; Eggen, Bart J. L.; Sperling, Reisa A.; Butovsky, Oleg
APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints
NATURE IMMUNOLOGY
IF27.6
2023-09-2551
OA
Yin, Zhuoran; Rosenzweig, Neta; Kleemann, Kilian L.; Zhang, Xiaoming; Brandao, Wesley; Margeta, Milica A.; Schroeder, Caitlin; Sivanathan, Kisha N.; Silveira, Sebastian; Gauthier, Christian; Mallah, Dania; Pitts, Kristen M.; Durao, Ana; Herron, Shawn; Shorey, Hannah; Cheng, Yiran; Barry, Jen-Li; Krishnan, Rajesh K.; Wakelin, Sam; Rhee, Jared; Yung, Anthony; Aronchik, Michael; Wang, Chao; Jain, Nimansha; Bao, Xin; Gerrits, Emma; Brouwer, Nieske; Deik, Amy; Tenen, Daniel G.; Ikezu, Tsuneya; Santander, Nicolas G.; Mckinsey, Gabriel L.; Baufeld, Caroline; Sheppard, Dean; Krasemann, Susanne; Nowarski, Roni; Eggen, Bart J. L.; Clish, Clary; Tanzi, Rudolph E.; Madore, Charlotte; Arnold, Thomas D.; Holtzman, David M.; Butovsky, Oleg
Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer’s disease
Nature Neuroscience
IF20
2023-06-080
PRE
Zhuoran Yin; Shawn Herron; Sebastian Silveira; Kilian Kleemann; Christian Gauthier; Dania Mallah; Yiran Cheng; Milica A. Margeta; Kristen M. Pitts; Jen-Li Barry; Ayshwarya Subramanian; Hannah Shorey; Wesley Brandao; Ana Durao; Jean-Christophe Delpech; Charlotte Madore; Mark Jedrychowski; Amrendra K. Ajay; Gopal Murugaiyan; Samuel W. Hersh; Seiko Ikezu; Tsuneya Ikezu; Oleg Butovsky

研究方向

暂未获取到该数据
O
Oleg Butovsky
H 指数:62论文数:161被引数:3.0万
N
Neta Rosenzweig
H 指数:9论文数:20被引数:2,988
G
Gabriel L. McKinsey
H 指数:18论文数:30被引数:2,035
D
Dean Sheppard
H 指数:114论文数:494被引数:4.5万
K
Kisha N. Sivanathan
H 指数:15论文数:26被引数:1,510
W
Wesley Nogueira Brandão
H 指数:15论文数:47被引数:2,186
Z
Zhuoran Yin
H 指数:18论文数:36被引数:3,231
B
Bart J. L. Eggen
H 指数:57论文数:284被引数:1.3万
I
Isabel Valenbreder
H 指数:1论文数:3被引数:70
T
Tsuneya Ikezu
H 指数:64论文数:227被引数:3.0万