未登录 Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes Artomov, Mykyta; Joseph, Vijai; Tiao, Grace; Thomas, Tinu; Schrader, Kasmintan; Klein, Robert J.; Kiezun, Adam; Gupta, Namrata; Margolin, Lauren; Stratigos, Alexander J.; Kim, Ivana; Shannon, Kristen; Ellisen, Leif W.; Haber, Daniel; Getz, Gad; Tsao, Hensin; Lipkin, Steven M.; Altshuler, David; Offit, Kenneth; Daly, Mark J. 分享 收藏
Rare germline variants in ATM are associated with chronic lymphocytic leukemia Tiao, G.; Improgo, M. R.; Kasar, S.; Poh, W.; Kamburov, A.; Landau, D-A; Tausch, E.; Taylor-Weiner, A.; Cibulskis, C.; Bahl, S.; Fernandes, S. M.; Hoang, K.; Rheinbay, E.; Kim, H. T.; Bahlo, J.; Robrecht, S.; Fischer, K.; Hallek, M.; Gabriel, S.; Lander, E. S.; Stilgenbauer, S.; Wu, C. J.; Kiezun, A.; Getz, G.; Brown, J. R. 分享 收藏
Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution Kasar, S.; Kim, J.; Improgo, R.; Tiao, G.; Polak, P.; Haradhvala, N.; Lawrence, M. S.; Kiezun, A.; Fernandes, S. M.; Bahl, S.; Sougnez, C.; Gabriel, S.; Lander, E. S.; Kim, H. T.; Getz, G.; Brown, J. R. 分享 收藏
Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes Shukla, Sachet A.; Rooney, Michael S.; Rajasagi, Mohini; Tiao, Grace; Dixon, Philip M.; Lawrence, Michael S.; Stevens, Jonathan; Lane, William J.; Dellagatta, Jamie L.; Steelman, Scott; Sougnez, Carrie; Cibulskis, Kristian; Kiezun, Adam; Hacohen, Nir; Brusic, Vladimir; Wu, Catherine J.; Getz, Gad 分享 收藏
Sensitive detection of somatic mutations in class I HLA genes reveals enrichment for functional events in cancer Shukla, Sachet A.; Rajasagi, Mohini; Dixon, Philip; Tiao, Grace; Lawrence, Michael S.; Sougnez, Carrie; Brusic, Vladimir; Cibulskis, Kristian; Kiezun, Adam; Wu, Catherine J.; Getz, Gad 分享 收藏
Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma 互补的基因组方法强调PI3K/mTOR途径是骨肉瘤的常见脆弱性 Perry, Jennifer A.; Kiezun, Adam; Tonzi, Peter; Van Allen, Eliezer M.; Carter, Scott L.; Baca, Sylvan C.; Cowley, Glenn S.; Bhatt, Ami S.; Rheinbay, Esther; Pedamallu, Chandra Sekhar; Helman, Elena; Taylor-Weiner, Amaro; McKenna, Aaron; DeLuca, David S.; Lawrence, Michael S.; Ambrogio, Lauren; Sougnez, Carrie; Sivachenko, Andrey; Walensky, Loren D.; Wagle, Nikhil; Mora, Jaume; de Torres, Carmen; Lavarino, Cinzia; Aguiar, Simone Dos Santos; Yunes, Jose Andres; Brandalise, Silvia Regina; Mercado-Celis, Gabriela Elisa; Melendez-Zajgla, Jorge; Cardenas-Cardos, Roco; Velasco-Hidalgo, Liliana; Roberts, Charles W. M.; Garraway, Levi A.; Rodriguez-Galindo, Carlos; Gabriel, Stacey B.; Lander, Eric S.; Golub, Todd R.; Orkin, Stuart H.; Getz, Gad; Janeway, Katherine A. 分享 收藏
The Genomic Landscape of Pediatric Ewing Sarcoma Crompton, Brian D.; Stewart, Chip; Taylor-Weiner, Amaro; Alexe, Gabriela; Kurek, Kyle C.; Calicchio, Monica L.; Kiezun, Adam; Carter, Scott L.; Shukla, Sachet A.; Mehta, Swapnil S.; Thorner, Aaron R.; de Torres, Carmen; Lavarino, Cinzia; Sunol, Mariona; McKenna, Aaron; Sivachenko, Andrey; Cibulskis, Kristian; Lawrence, Michael S.; Stojanov, Petar; Rosenberg, Mara; Ambrogio, Lauren; Auclair, Daniel; Seepo, Sara; Blumenstiel, Brendan; DeFelice, Matthew; Imaz-Rosshandler, Ivan; Schwarz-Cruz y Celis, Angela; Rivera, Miguel N.; Rodriguez-Galindo, Carlos; Fleming, Mark D.; Golub, Todd R.; Getz, Gad; Mora, Jaume; Stegmaier, Kimberly 分享 收藏
Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma Kiezun, Adam; Perry, Jennifer; Tonzi, Peter; Van Allen, Eliezer; Carter, Scott L.; Baca, Sylvan; Bhatt, Ami; Lawrence, Michael; Walensky, Loren; Wagle, Nikhil; Mora, Jaume; de Torres, Carmen; Lavarino, Cinzia; Velasco-Hidalgo, Liliana; Cardenas-Cardos, Rocio; Aguiar, Simone dos Santos; Yunes, Jose A.; Mercado, Gabriela; Melendez-Zajgla, Jorge; Roberts, Charles; Garraway, Levi; Rodriguez-Galindo, Carlos; Golub, Todd; Orkin, Stuart; Getz, Gad; Janeway, Katherine 分享 收藏
分享 收藏
The genomic landscape of pediatric Ewing sarcoma Crompton, Brian; Stewart, Chip; Taylor-Weiner, Amaro; Alexa, Gabriela; Kurek, Kyle; Calicchio, Monica; Kiezun, Adam; Carter, Scott; Shukla, Sachet; Mehta, Swapnil; Thorner, Aaron; De Torres, Carmen; Lavarino, Cinzia; Sunol, Mariona; McKenna, Aaron; Sivachenko, Andrey; Cibulskis, Kristian; Lawrence, Michael; Ambrogio, Lauren; Auclair, Daniel; Rosshandler, Ivan; Celis, Angela Schwarz-Cruz Y.; Rivera, Miguel; Rodriguez-Galindo, Carlos; Fleming, Mark; Golub, Todd; Getz, Gad; Mora, Jaume; Stegmaier, Kimberly 分享 收藏
Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences Pugh, T. J.; Yu, W.; Yang, J.; Field, A. L.; Ambrogio, L.; Carter, S. L.; Cibulskis, K.; Giannikopoulos, P.; Kiezun, A.; Kim, J.; McKenna, A.; Nickerson, E.; Getz, G.; Hoffher, S.; Messinger, Y. H.; Dehner, L. P.; Roberts, C. W. M.; Rodriguez-Galindo, C.; Williams, G. M.; Rossi, C. T.; Meyerson, M.; Hill, D. A. 分享 收藏
Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine 福尔马林固定石蜡包埋肿瘤标本全外显子组测序及临床解读指导精准肿瘤医学 Van Allen, Eliezer M.; Wagle, Nikhil; Stojanov, Petar; Perrin, Danielle L.; Cibulskis, Kristian; Marlow, Sara; Jane-Valbuena, Judit; Friedrich, Dennis C.; Kryukov, Gregory; Carter, Scott L.; McKenna, Aaron; Sivachenko, Andrey; Rosenberg, Mara; Kiezun, Adam; Voet, Douglas; Lawrence, Michael; Lichtenstein, Lee T.; Gentry, Jeff G.; Huang, Franklin W.; Fostel, Jennifer; Farlow, Deborah; Barbie, David; Gandhi, Leena; Lander, Eric S.; Gray, Stacy W.; Joffe, Steven; Janne, Pasi; Garber, Judy; MacConaill, Laura; Lindeman, Neal; Rollins, Barrett; Kantoff, Philip; Fisher, Sheila A.; Gabriel, Stacey; Getz, Gad; Garraway, Levi A. 分享 收藏
An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers APOBEC胞苷脱氨酶诱变模式在人类癌症中广泛存在 Roberts, Steven A.; Lawrence, Michael S.; Klimczak, Leszek J.; Grimm, Sara A.; Fargo, David; Stojanov, Petar; Kiezun, Adam; Kryukov, Gregory V.; Carter, Scott L.; Saksena, Gordon; Harris, Shawn; Shah, Ruchir R.; Resnick, Michael A.; Getz, Gad; Gordenin, Dmitry A. 分享 收藏
Progressive biallelic loss of TP53 is associated with progression of pleuropulmonary blastoma initiated by germline loss and somatic mutation of DICER1 Pugh, Trevor J.; Yu, Weiying; Yang, Jiandong; Ambrogio, Lauren; Carter, Scott L.; Kiezun, Adam; McKenna, Aaron; Giannikopoulos, Petros; Getz, Gad; Messinger, Yoav; Meyerson, Matthew; Hill, D. Ashley 分享 收藏
Deleterious Alleles in the Human Genome Are on Average Younger Than Neutral Alleles of the Same Frequency 人类基因组中的有害等位基因平均比相同频率的中性等位基因年轻 Kiezun, Adam; Pulit, Sara L.; Francioli, Laurent C.; van Dijk, Freerk; Swertz, Morris; Boomsma, Dorret I.; van Duijn, Cornelia M.; Slagboom, P. Eline; van Ommen, G. J. B.; Wijmenga, Cisca; de Bakker, Paul I. W.; Sunyaev, Shamil R. 分享 收藏
分享 收藏
Exome sequencing and the genetic basis of complex traits 外显子组测序与复杂性状的遗传基础 Kiezun, Adam; Garimella, Kiran; Do, Ron; Stitziel, Nathan O.; Neale, Benjamin M.; McLaren, Paul J.; Gupta, Namrata; Sklar, Pamela; Sullivan, Patrick F.; Moran, Jennifer L.; Hultman, Christina M.; Lichtenstein, Paul; Magnusson, Patrik; Lehner, Thomas; Shugart, Yin Yao; Price, Alkes L.; de Bakker, Paul I. W.; Purcell, Shaun M.; Sunyaev, Shamil R. 分享 收藏
Development and Validation of a Computational Method for Assessment of Missense Variants in Hypertrophic Cardiomyopathy Jordan, Daniel M.; Kiezun, Adam; Baxter, Samantha M.; Agarwala, Vineeta; Green, Robert C.; Murray, Michael F.; Pugh, Trevor; Lebo, Matthew S.; Rehm, Heidi L.; Funke, Birgit H.; Sunyaev, Shamil R. 分享 收藏
分享 收藏
分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
