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S

Sourav Das

st jude childrens research hospital
H指数:16
被引数:1,131

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工作经历

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荣誉奖项

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Differential Water Networks Guide Selectivity Optimization of a Cell Active BPTF Inhibitor in Neuroblastoma

差异性水网络指导神经母细胞瘤中细胞活性BPTF抑制剂的靶向选择性优化

Angewandte Chemie-International Edition
IF16.9
2026-09-120
OAAI
Kesavan Babu; Chun-Ju Tsou; Sourav Das; Liying Fan; Anasuya Pal; Molly Sneddon; Timothy R. Stachowski; Priyanka Samanta; Stanley Nithianantham; Caroline Buchholz; Shi Zhang; Xiang Fu; Rahul S. Kathayat; Wenwei Lin; Yongtao Li; Lei Yang; Taosheng Chen; Marcus Fischer; Anang A. Shelat; William C. K. Pomerantz
Structure-Activity Relationship of Potent, Selective, and Orally Bioavailable Molecular Glue Degraders of CK1α

CK1α 的有效，选择性和口服生物利用度分子胶降解剂的构效关系

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2024-09-121
PRE
Nishiguchi, Gisele; Caine, Elizabeth A.; Mcgowan, Kevin; Shi, Zhe; Aggarwal, Anup; Mayasundari, Anand; Price, Jeanine; Yang, Lei; Li, Yong; Fu, Xiang; Mascibroda, Lauren G.; Das, Sourav; Daniels, Danette L.; Urh, Marjeta; Klco, Jeffery M.; Riching, Kristin M.; Rankovic, Zoran
Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines
NATURE COMMUNICATIONS
IF15.7
2024-01-169
OAAI
Nishiguchi, Gisele; Mascibroda, Lauren G.; Young, Sarah M.; Caine, Elizabeth A.; Abdelhamed, Sherif; Kooijman, Jeffrey J.; Miller, Darcie J.; Das, Sourav; McGowan, Kevin; Mayasundari, Anand; Shi, Zhe; Barajas, Juan M.; Hiltenbrand, Ryan; Aggarwal, Anup; Chang, Yunchao; Mishra, Vibhor; Narina, Shilpa; Thomas, Melvin; Loughran, Allister J.; Kalathur, Ravi; Yu, Kaiwen; Zhou, Suiping; Wang, Xusheng; High, Anthony A.; Peng, Junmin; Pruett-Miller, Shondra M.; Daniels, Danette L.; Urh, Marjeta; Shelat, Anang A.; Mullighan, Charles G.; Riching, Kristin M.; Zaman, Guido J. R.; Fischer, Marcus; Klco, Jeffery M.; Rankovic, Zoran
Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs

苯基戊二酰亚胺: 用于PROTACs设计的替代cerebon粘合剂

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
2021-11-1678
OA
Min, Jaeki; Mayasundari, Anand; Keramatnia, Fatemeh; Jonchere, Barbara; Yang, Seung Wook; Jarusiewicz, Jamie; Actis, Marisa; Das, Sourav; Young, Brandon; Slavish, Jake; Yang, Lei; Li, Yong; Fu, Xiang; Garrett, Shalandus H.; Yun, Mi-Kyung; Li, Zhenmei; Nithianantham, Stanley; Chai, Sergio; Chen, Taosheng; Shelat, Anang; Lee, Richard E.; Nishiguchi, Gisele; White, Stephen W.; Roussel, Martine F.; Potts, Patrick Ryan; Fischer, Marcus; Rankovic, Zoran
Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-05-2763
OAAI
Nishiguchi, Gisele; Keramatnia, Fatemeh; Min, Jaeki; Chang, Yunchao; Jonchere, Barbara; Das, Sourav; Actis, Marisa; Price, Jeanine; Chepyala, Divyabharathi; Young, Brandon; McGowan, Kevin; Slavish, P. Jake; Mayasundari, Anand; Jarusiewicz, Jamie A.; Yang, Lei; Li, Yong; Fu, Xiang; Garrett, Shalandus H.; Papizan, James B.; Kodali, Kiran; Peng, Junmin; Miller, Shondra M. Pruett; Roussel, Martine F.; Mullighan, Charles; Fischer, Marcus; Rankovic, Zoran
Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer
CANCER RESEARCH
IF16.6
2020-09-0231
OAAI
Slavish, P. Jake; Chi, Liying; Yun, Mi-Kyung; Tsurkan, Lyudmila; Martinez, Nancy E.; Jonchere, Barbara; Chai, Sergio C.; Connelly, Michele; Waddell, M. Brett; Das, Sourav; Neale, Geoffrey; Li, Zhenmei; Shadrick, William R.; Olsen, Rachelle R.; Freeman, Kevin W.; Low, Jonathan A.; Price, Jeanine E.; Young, Brandon M.; Bharatham, Nagakumar; Boyd, Vincent A.; Yang, Jun; Lee, Richard E.; Morfouace, Marie; Roussel, Martine F.; Chen, Taosheng; Savic, Daniel; Guy, R. Kiplin; White, Stephen W.; Shelat, Anang A.; Potter, Philip M.
Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox
CANCER RESEARCH
IF16.6
2017-08-3144
OAAI
Yang, Jun; Milasta, Sandra; Hu, Dongli; AlTahan, Alaa M.; Interiano, Rodrigo B.; Zhou, Junfang; Davidson, Jesse; Low, Jonathan; Lin, Wenwei; Bao, Ju; Goh, Pollyanna; Nathwani, Amit C.; Wang, Ruoning; Wang, Yingdi; Ong, Su Sien; Boyd, Vincent A.; Young, Brandon; Das, Sourav; Shelat, Anang; Wu, Yinan; Li, Zhenmei; Zheng, Jie J.; Mishra, Ashutosh; Cheng, Yong; Qu, Chunxu; Peng, Junmin; Green, Douglas R.; White, Stephen; Guy, R. Kiplin; Chen, Taosheng; Davidoff, Andrew M.
Structure-Activity Relationships of Spectinamide Antituberculosis Agents: A Dissection of Ribosomal Inhibition and Native Efflux Avoidance Contributions

Spectinamide抗结核药的结构-活性关系: 核糖体抑制和自然流出避免贡献的剖析

ACS INFECTIOUS DISEASES
IF3.8
2016-11-1143
OAAI
Liu, Jiuyu; Bruhn, David F.; Lee, Robin B.; Zheng, Zhong; Janusic, Tana; Scherbakov, Dimitri; Scherman, Michael S.; Boshoff, Helena I.; Das, Sourav; Rakesh; Waidyarachchi, Samanthi L.; Brewer, Tiffany A.; Gracia, Begona; Yang, Lei; Bollinger, John; Robertson, Gregory T.; Meibohm, Bernd; Lenaerts, Anne J.; Ainsa, Jose; Boettger, Erik C.; Lee, Richard E.

研究方向

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A
Anang A. Shelat
H 指数:42论文数:249被引数:6,724
R
Richard Lee
H 指数:91论文数:1,628被引数:3.2万
Z
Zoran Ranković
H 指数:30论文数:219被引数:6,137
S
Stephen W. White
H 指数:61论文数:277被引数:1.3万
G
Gisele Nishiguchi
H 指数:19论文数:68被引数:1,987
T
Taosheng Chen
H 指数:50论文数:297被引数:7,769
B
Brandon Young
H 指数:31论文数:137被引数:3,578
M
Marcus Fischer
H 指数:33论文数:161被引数:4,708
L
Lei Yang
H 指数:32论文数:113被引数:2,940
Z
Zhenmei Li
H 指数:15论文数:99被引数:1,416