Rosalind A. Segal

harvard medical school

58H指数

194论文数

1.7W被引数

收录论文 64

发表时间

RBP-Driven RNA sorting and local translation establish the molecular identities of individual sensory axons RBP驱动的RNA分类和局部翻译确立单个感觉轴突的分子特性

Nature Communications

IF15.7

2026-08-31

OAAI

Elizabeth S. Silagi; Ezechukwu Nduka; Jesus Zuniga Paiz; Maria F. Pazyra-Murphy; Shamsuddin A. Bhuiyan; William Renthal; Rosalind A. Segal

An enantioselective covalent inhibitor of BAX confers cytoprotection in vivo BAX的手性选择性共价抑制剂可赋予体内细胞保护作用

Nature Chemical Biology

IF13.7

2026-08-28

OAAI

Peiwen Shi; Bruno Melillo; Matthew W. McHenry; Christina M. Camara; Ka Yang; Evert Njomen; Marina Godes; Maria F. Pazyra-Murphy; Mary Rose Branch; Bethany Tesar; Rosalind A. Segal; Lee L. Rubin; Michael D. Cameron; Gregory H. Bird; Thomas E. Wales; Steven P. Gygi; Benjamin F. Cravatt; Loren D. Walensky

Polarized Signaling Endosomes Coordinate BDNF-Induced Chemotaxis of Cerebellar Precursors 极化信号内体协调BDNF诱导的小脑前体细胞的化学趋向性

Neuron

IF15

2025-11-15

PREAI

Pengcheng Zhou; Marimelia Porcionatto; Mariecel Pilapil; Yicheng Chen; Yoojin Choi; Kimberley F. Tolias; Jay B. Bikoff; Elizabeth J. Hong; Michael E. Greenberg; Rosalind A. Segal

H3G34-MUTANT DIFFUSE HEMISPHERIC GLIOMAS CONTAIN CELLULAR NICHES OF GABAERGIC INTERNEURON-LIKE CELLS WITH DUAL FREQUENCY AUTONOMOUS RHYTHMIC CALCIUM ACTIVITY H3G34-突变弥漫性半球胶质瘤包含具有双频自主节律性钙活动的γ-氨基丁酸能中间神经元样细胞的细胞微环境

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Cruzeiro, Gustavo Alencastro Veiga; Buhse, Johann; Cascio, Costanza Lo; Neyazi, Sina; Katiyar, Shashank; Tabatabai, Kuscha; Taylor, Kathryn; De Biagi Jr, Carlos Alberto Oliveira; Haase, Rebecca; Sarwnow, Katharina; Venkataramani, Varun; Liu, Ilon; Huang, Kun; Murphy, Maria Pazyra; Schuller, Ulrich; Segal, Rosalind; Tang, Xin; Monje, Michelle; Filbin, Mariella

Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons 卫星胶质细胞接触增强了人类iPSC来源的感觉神经元的分化和成熟。

Stem Cell Reports

IF5.1

2025-09-18

PREAI

Chelsey J. LeBlang; Maria F. Pazyra-Murphy; Elizabeth S. Silagi; Srestha Dasgupta; Marianna Tsolias; Toussaint Miller; Veselina Petrova; Shannon Zhen; Vukasin M. Jovanovic; David Castellano; Kathryn Gerrish; Pinar Ormanoglu; Carlos A. Tristan; Ilyas Singeç; Clifford J. Woolf; Ozge Tasdemir-Yilmaz; Rosalind A. Segal

Dissecting the neuroprotective interaction between the BH4 domain of BCL-w and the IP3 receptor

CELL CHEMICAL BIOLOGY

IF7.2

2024-10-01

PREAI

Tang, Sophia X.; Camara, Christina M.; Franco, Joy A.; Pazyra-Murphy, Maria F.; Li, Yihang; Godes, Marina; Moyer, Benjamin M.; Bird, Gregory H.; Segal, Rosalind A.; Walensky, Loren D.

Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2024-08-07

OAAI

Tsiami, Foteini; Lago, Chiara; Pozza, Noemi; Piccioni, Federica; Zhao, Xuesong; Luelsberg, Fabienne; Root, David E.; Tiberi, Luca; Kool, Marcel; Schittenhelm, Jens; Bandopadhayay, Pratiti; Segal, Rosalind A.; Tabatabai, Ghazaleh; Merk, Daniel J.

THE GABAERGIC INTERNEURONAL AND NEURAL PROGENITOR LINEAGE OF THE DIFFUSE HEMISPHERIC GLIOMA, H3 G34-MUTANT, SHOW CALCIUM EVENTS IN THE FORM OF INTERCELLULAR WAVES AND SPONTANEOUS ELECTRICAL ACTIVITY

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Cruzeiro, Gustavo Alencastro Veiga; Cascio, Costanza Lo; Neyazi, Sina; Biagi Jr, Carlos Alberto Oliveira; Haase, Rebecca; Nascimento, Andrezza; Frederico, Stephen Charles; Sarnow, Katharina; Venkataramani, Varun; Liu, Ilon; Huang, Kun; Tang, Xin; Segal, Rosalind; Monje, Michelle; Filbin, Mariella

Satellite Glial Cells: No Longer the Most Overlooked Glia 卫星胶质细胞：不再是最被忽视的胶质细胞

cold spring harbor perspectives in medicine

IF8.4

2024-05-20

PREAI

Birren, Susan J.; Goodrich, Lisa V.; Segal, Rosalind A.

A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma

CANCER RESEARCH

IF16.6

2024-01-17

OAAI

Hwang, Grace H.; Pazyra-Murphy, Maria F.; Seo, Hyuk-Soo; Dhe-Paganon, Sirano; Stopka, Sylwia A.; Dipiazza, Marina; Sutter, Nizhoni; Gero, Thomas W.; Volkert, Alison; Ombelets, Lincoln; Dittemore, Georgia; Rees, Matthew G.; Ronan, Melissa M.; Roth, Jennifer A.; Agar, Nathalie Y. R.; Scott, David A.; Segal, Rosalind A.

Developmental basis of SHH medulloblastoma heterogeneity

NATURE COMMUNICATIONS

IF15.7

2024-01-08

OAAI

Gold, Maxwell P.; Ong, Winnie; Masteller, Andrew M.; Ghasemi, David R.; Galindo, Julie Anne; Park, Noel R.; Huynh, Nhan C.; Donde, Aneesh; Pister, Veronika; Saurez, Raul A.; Vladoiu, Maria C.; Hwang, Grace H.; Eisemann, Tanja; Donovan, Laura K.; Walker, Adam D.; Benetatos, Joseph; Dufour, Christelle; Garzia, Livia; Segal, Rosalind A.; Wechsler-Reya, Robert J.; Mesirov, Jill P.; Korshunov, Andrey; Pajtler, Kristian W.; Pomeroy, Scott L.; Ayrault, Olivier; Davidson, Shawn M.; Cotter, Jennifer A.; Taylor, Michael D.; Fraenkel, Ernest

Sustained signaling by phospholipase C-γ mediates nerve growth factor-triggered gene expression

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Choi, DY; Toledo-Aral, JJ; Segal, R; Halegoua, S

TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system TMEM161B在发育中的中枢神经系统中调节大脑皮层回旋，声波刺猬信号和睫状结构

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-01-20

OAAI

Akula, Shyam K.; Marciano, Jack H.; Lim, Youngshin; Exposito-Alonso, David; Hylton, Norma K.; Hwang, Grace H.; Neil, Jennifer E.; Dominado, Nicole; Bunton-Stasyshyn, Rosie K.; Song, Janet H. T.; Talukdar, Maya; Schmid, Aloisia; Teboul, Lydia; Mo, Alisa; Shin, Taehwan; Finander, Benjamin; Beck, Samantha G.; Yeh, Rebecca C.; Otani, Aoi; Qian, Xuyu; DeGennaro, Ellen M.; Alkuraya, Fowzan S.; Maddirevula, Sateesh; Cascino, Gregory D.; Giannini, Caterina; Undiagnosed Diseases Network, Lindsay C.; Burrage, Lindsay C.; Rosenfield, Jill A.; Ketkar, Shamika; Clark, Gary D.; Bacino, Carlos; Lewis, Richard A.; Segal, Rosalind A.; Bazan, J. Fernando; Smith, Kelly A.; Golden, Jeffrey A.; Cho, Ginam; Walsh, Christopher A.

An affinity for brainstem microglia in pediatric high-grade gliomas of brainstem origin

NEURO-ONCOLOGY ADVANCES

IF4.1

2022-07-21

OAAI

Zats, Liat Peretz; Ahmad, Labiba; Casden, Natania; Lee, Meelim J.; Belzer, Vitali; Adato, Orit; Bar Cohen, Shaked; Ko, Seung-Hyun B.; Filbin, Mariella G.; Unger, Ron; Lauffenburger, Douglas A.; Segal, Rosalind A.; Behar, Oded

Synthetic extracellular matrices and astrocytes provide a supportive microenvironment for the cultivation and investigation of primary pediatric gliomas

NEURO-ONCOLOGY ADVANCES

IF4.1

2022-04-13

OAAI

Rota, Christopher M.; Brown, Alexander T.; Addleson, Emily; Ives, Clara; Trumper, Ella; Pelton, Kristine; Teh, Wei Pin; Schniederjan, Matthew J.; Castellino, Robert Craig; Buhrlage, Sara; Lauffenburger, Douglas A.; Ligon, Keith L.; Griffith, Linda G.; Segal, Rosalind A.

Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN

JOURNAL OF CELL BIOLOGY

IF6.4

2021-12-22

OAAI

Li, Yihang; Pazyra-Murphy, Maria F.; Avizonis, Daina; Russo, Mariana de Sa Tavares; Tang, Sophia; Chen, Chiung-Ya; Hsueh, Yi-Ping; Bergholz, Johann S.; Jiang, Tao; Zhao, Jean J.; Zhu, Jian; Ko, Kwang Woo; Milbrandt, Jeffrey; DiAntonio, Aaron; Segal, Rosalind A.

Diversity of developing peripheral glia revealed by single-cell RNA sequencing

DEVELOPMENTAL CELL

IF8.7

2021-09-01

OAAI

Tasdemir-Yilmaz, Ozge E.; Druckenbrod, Noah R.; Olukoya, Olubusola O.; Dong, Weixiu; Yung, Andrea R.; Bastille, Isle; Pazyra-Murphy, Maria F.; Sitko, Austen A.; Hale, Evan B.; Vigneau, Sebastien; Gimelbrant, Alexander A.; Kharchenko, Peter, V; Goodrich, Lisa, V; Segal, Rosalind A.

DEVELOPING EYA PHOSPHATASE INHIBITORS WITH ON-TARGET EFFECTS IN SHH-MEDULLOBLASTOMA

NEURO-ONCOLOGY

IF13.4

2021-06-01

OAAI

Hwang, Grace H.; Scott, David A.; Segal, Rosalind A.

Uncomfortably numb: how Nav1.7 mediates paclitaxel-induced peripheral neuropathy

BRAIN

IF11.7

2021-05-19

OAAI

Silagi, Elizabeth S.; Segal, Rosalind A.