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L

Lynn Quek

king's college london
H指数:29
被引数:6,607

个人简介

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荣誉奖项

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SLIT2 modulates leukaemic cell proliferation and stromal support in acute myeloid leukaemia models

SLIT2调节急性髓系白血病模型中白血病细胞的增殖和基质支持

British Journal of Haematology
IF3.8
2026-09-290
PRE
Luise Albuquerque-Simões; Isabel Weinhäuser; Diego A. Pereira-Martins; César Alexander Ortiz Rojas; Lúcio Henrique Sousa Pinheiro; Livia Bassani Lins de Miranda; Thiago Mantello Bianco; Rita de Cássia Cavaglieri; Mariane Cristina do Nascimento; Lynn Quek; Steffen Boettcher; Jan Jacob Schuringa; Eduardo Magalhães Rego
Metformin induces ferroptosis associated with lipidomic remodeling in AML

二甲双胍诱导与脂质组重塑相关的铁死亡在AML中

Blood Advances
IF7.1
2025-11-040
OAAI
Dominique Sternadt; Diego A. Pereira-Martins; Prodromos Chatzikyriakou; Luise Albuquerque-Simões; Ming Yang; Douglas R.A. Silveira; Albertus T.J. Wierenga; Isabel Weinhäuser; Shanna M. Hogeling; Lieve L. Oudejans; Pilar Casares Alaez; Jean-Emmanuel Sarry; Christian Frezza; Gerwin A. Huls; Lynn Quek; Jan Jacob Schuringa
High mtDNA content identifies oxidative phosphorylation-driven acute myeloid leukemias and represents a therapeutic vulnerability

高mtDNA含量可识别氧化磷酸化驱动的急性髓性白血病，并代表治疗脆弱性

Signal Transduction and Targeted Therapy
IF52.7
2025-07-140
OAAI
Diego A. Pereira-Martins; Isabel Weinhäuser; Emmanuel Griessinger; Juan L. Coelho-Silva; Douglas R. Silveira; Dominique Sternadt; Ayşegül Erdem; Bruno Kosa L. Duarte; Prodromos Chatzikyriakou; Lynn Quek; Antonio Bruno Alves-Silva; Fabiola Traina; Sara T. Olalla Saad; Jacobien R. Hilberink; Amanda Moreira-Aguiar; Maria L. Salustiano-Bandeira; Marinus M. Lima; Pedro L. Franca-Neto; Marcos A. Bezerra; Nisha K. van der Meer; Emanuele Ammatuna; Eduardo M. Rego; Gerwin Huls; Jan Jacob Schuringa; Antonio R. Lucena-Araujo
Ethnic variations in neutrophil count as predictors of prognosis following acute myocardial infarction

中性粒细胞计数中的种族差异作为急性心肌梗死后预后的预测因子

ATHEROSCLEROSIS
IF5.7
2025-04-010
OAAI
Sadler, Matthew; Cannata, Antonio; Mackie, Sarah; Anandhakrishna, Rupavidhya Mondi; Argunhan, Fulye; Ferone, Emma; Mohammad, Al-Agil; Salim, Jamila; Tantichirasakul, Narun; Lam, Mei Tung; Ambon, Josel; Shamsi, Aamir; Piper, Susan; Napolitani, Giorgio; Shah, Ajay M.; McDonagh, Theresa; Scott, Paul A.; Quek, Lynn; Bromage, Daniel I.
DGATI Inhibition Enhances Metformin-Induced Ferroptosis in AML By Targeting Lipid Metabolism

DGATI 抑制通过靶向脂质代谢增强二甲双胍诱导的AML中铁死亡

BLOOD
IF23.1
2024-11-051
PRE
Sternadt, Dominique; Pereira-Martins, Diego A.; Silveira, Douglas R. A.; Weinhaeuser, Isabel; Yang, Ming; Chatzikyriakou, Prodromos; Alaez, Pilar Casares; Erdem, Aysegul; Oudejans, Lieve; Hogeling, Shanna; Ammatuna, Emanuele; Huls, Gerwin; Frezza, Christian; Quek, Lynn; Schuringa, Jan Jacob
The Oncogenic Function of the Intrinsically Disordered Transcriptional Regulator MN1 Depends on the Chaperone DNAJB6b

内源无序转录调控因子MN1的致癌功能依赖于分子伴侣DNAJB6b

BLOOD
IF23.1
2024-11-050
PRE
Pereira-Martins, Diego A.; van den Boom, Vincent; Weinhaeuser, Isabel; van der Meer, Nisha; Chatzikyriakou, Prodromos; van Dijk, Noortje; Zheng, Xuesen; Pinheiro, Lucio H.; Silveira, Douglas R. A.; Bianco, Thiago Mantello; Rojas, Cesar Alexander Ortiz; Rego, Eduardo M.; Rushworth, Stuart A.; Lucena-Araujo, Antonio R.; Quek, Lynn; Huls, Gerwin; Schuringa, Jan Jacob
M2 macrophages drive leukemic transformation by imposing resistance to phagocytosis and improving mitochondrial metabolism
SCIENCE ADVANCES
IF12.5
2023-04-1418
OAAI
Weinhauser, Isabel; Pereira-Martins, Diego A.; Almeida, Luciana Y.; Hilberink, Jacobien R.; Silveira, Douglas R. A.; Quek, Lynn; Ortiz, Cesar; Araujo, Cleide L.; Bianco, Thiago M.; Lucena-Araujo, Antonio; Mota, Jose Mauricio; Hogeling, Shanna M.; Sternadt, Dominique; Visser, Nienke; Diepstra, Arjan; Ammatuna, Emanuele; Huls, Gerwin; Rego, Eduardo M.; Schuringa, Jan Jacob
Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation
CELL REPORTS
IF6.9
2021-05-0127
OAAI
Crump, Nicholas T.; Hadjinicolaou, Andreas, V; Xia, Meng; Walsby-Tickle, John; Gileadi, Uzi; Chen, Ji-Li; Setshedi, Mashiko; Olsen, Lars R.; Lau, I-Jun; Godfrey, Laura; Quek, Lynn; Yu, Zhanru; Ballabio, Erica; Barnkob, Mike B.; Napolitani, Giorgio; Salio, Mariolina; Koohy, Hashem; Kessler, Benedikt M.; Taylor, Stephen; Vyas, Paresh; McCullagh, James S. O.; Milne, Thomas A.; Cerundolo, Vincenzo
Integrating clinical features with genetic factors enhances survival prediction for adults with acute myeloid leukemia
BLOOD ADVANCES
IF7.1
2020-05-2612
OAAI
Silveira, Douglas R. A.; Quek, Lynn; Santos, Itamar S.; Corby, Anna; Coelho-Silva, Juan L.; Pereira-Martins, Diego A.; Vallance, Grant; Brown, Benjamin; Nardinelli, Luciana; Silva, Wellington F.; Velloso, Elvira D. R. P.; Lucena-Araujo, Antonio R.; Traina, Fabiola; Peniket, Andy; Vyas, Paresh; Rego, Eduardo M.; Bendit, Israel; Rocha, Vanderson
Molecular mechanisms mediating relapse following ivosidenib monotherapy in IDH1-mutant relapsed or refractory AML
BLOOD ADVANCES
IF7.1
2020-05-07145
OAAI
Choe, Sung; Wang, Hongfang; DiNardo, Courtney D.; Stein, Eytan M.; de Botton, Stephane; Roboz, Gail J.; Altman, Jessica K.; Mims, Alice S.; Watts, Justin M.; Pollyea, Daniel A.; Fathi, Amir T.; Tallman, Martin S.; Kantarjian, Hagop M.; Stone, Richard M.; Quek, Lynn; Konteatis, Zenon; Dang, Lenny; Nicolay, Brandon; Nejad, Parham; Liu, Guowen; Zhang, Vickie; Liu, Hua; Goldwasser, Meredith; Liu, Wei; Marks, Kevin; Bowden, Chris; Biller, Scott A.; Attar, Eyal C.; Wu, Bin
TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups
LEUKEMIA
IF13.4
2019-01-11177
OAAI
Haase, Detlef; Stevenson, Kristen E.; Neuberg, Donna; Maciejewski, Jaroslaw P.; Nazha, Aziz; Sekeres, Mikkael A.; Ebert, Benjamin L.; Garcia-Manero, Guillermo; Haferlach, Claudia; Haferlach, Torsten; Kern, Wolfgang; Ogawa, Seishi; Nagata, Yasunobu; Yoshida, Kenichi; Graubert, Timothy A.; Walter, Matthew J.; List, Alan F.; Komrokji, Rami S.; Padron, Eric; Sallman, David; Papaemmanuil, Elli; Campbell, Peter J.; Savona, Michael R.; Seegmiller, Adam; Ades, Lionel; Fenaux, Pierre; Shih, Lee-Yung; Bowen, David; Groves, Michael J.; Tauro, Sudhir; Fontenay, Michaela; Kosmider, Olivier; Bar-Natan, Michal; Steensma, David; Stone, Richard; Heuser, Michael; Thol, Felicitas; Cazzola, Mario; Malcovati, Luca; Karsan, Aly; Ganster, Christina; Hellstrom-Lindberg, Eva; Boultwood, Jacqueline; Pellagatti, Andrea; Santini, Valeria; Quek, Lynn; Vyas, Paresh; Tuechler, Heinz; Greenberg, Peter L.; Bejar, Rafael
Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib
NATURE MEDICINE
IF50
2018-07-16146
OAAI
Quek, Lynn; David, Muriel D.; Kennedy, Alison; Metzner, Marlen; Amatangelo, Michael; Shih, Alan; Stoilova, Bilyana; Quivoron, Cyril; Heiblig, Mael; Willekens, Christophe; Saada, Veronique; Alsafadi, Samar; Vijayabaskar, M. S.; Peniket, Andy; Bernard, Oliver A.; Agresta, Sam; Yen, Katharine; MacBeth, Kyle; Stein, Eytan; Vassiliou, George S.; Levine, Ross; De Botton, Stephane; Thakurte, Anjan; Penard-Lacronique, Virginie; Vyas, Paresh

研究方向

暂未获取到该数据
P
Paresh Vyas
H 指数:93论文数:622被引数:4.4万
D
Diego A. Pereira‐Martins
H 指数:16论文数:159被引数:873
J
Jan Jacob Schuringa
H 指数:48论文数:321被引数:6,903
E
Eduardo Magalhães Rego
H 指数:44论文数:651被引数:8,336
D
Douglas RA Silveira
H 指数:10论文数:48被引数:387
I
Isabel Weinhäuser
H 指数:9论文数:66被引数:573
G
Gerwin Huls
H 指数:44论文数:287被引数:7,748
A
Alison Kennedy
H 指数:11论文数:28被引数:938
C
Charles Craddock
H 指数:72论文数:545被引数:2.1万
P
Prodromos Chatzikyriakou
H 指数:4论文数:24被引数:85