Jens Puschhof - Publications, H-index & Citations

Jens Puschhof

german cancer research center

28H指数

52论文数

5.8K被引数

收录论文 25

发表时间

Windows of Opportunity for Genotoxic E. coli in Colorectal Cancer Initiation 结直肠癌起始过程中致突变性大肠杆菌的机会窗口

Journal of Applied Microbiology

IF3.2

2026-07-30

PREAI

Jarryd Michael Boath; Luigi Lukas Nardella; Jens Puschhof

TROP2 targeting reveals therapy-driven cell state dynamics in colorectal cancer TROP2靶向揭示结直肠癌中治疗驱动的细胞状态动力学

Nature

IF48.5

2026-07-01

OAAI

Nuria Vaquero-Siguero; Nikolaos Georgakopoulos; Maria C. Puschhof; Ioannis Chiotakakos; Jasmin Meier; Sigrid K. Fey; Gabriele Diamante; Manuel Mastel; Aitana Guiseris-Martinez; Guillaume Belthier; Nikolai Schleußner; Julia Volk; Carolin Artmann; Bryce Lim; Ronald Koschny; Cyrill Wehling; Kyanna S. Ouyang; Michael Günther; Solveig Kuss; Paula Hoffmeister; Moritz Mall; Jens Neumann; Steffen Ormanns; Martin Schneider; Thomas Schmidt; Jens Puschhof; Andreas Trumpp; Jacco van Rheenen; Julio Saez-Rodriguez; Bruno C. Köhler; Rene Jackstadt

Human immunodeficiency virus-associated gut microbiome impacts systemic immunodeficiency and susceptibility to opportunistic gut infection 人类免疫缺陷病毒相关的肠道菌群会影响系统性免疫缺陷和机会性肠道感染的易感性

Nature Microbiology

IF19.4

2026-02-16

PREAI

Stavros Bashiardes; Melina Heinemann; Lorenz Adlung; Rafael Valdés-Mas; Jemal Ali Mahdi; Samuel P. Nobs; Timur Tuganbaev; Takahiro Yamada; Max Horn; Uria Mor; Yotam Cohen; Sarah Israel; Maya Korem; Yonatan Oster; Karen Olshtain-Pops; Efrat Orenbuch-Harroch; Muhammed Dervis Arslan; Shahar Molina; Maya Zur; Shimrit Eliyahu-Miller; Aurélie Bukimer; Sara Federici; Mally Dori-Bachash; Nira Amar; Daniel Elbirt; Ronit Cohen-Poradosu; Dan Turner; Tiberiu Hershcovici; Elez Vainer; Noa Stettner; Alon Harmelin; Hailay Gebremeskel; Yazezew Kebede; Sabine Schmidt; Niv Zmora; Arunraj Dhamodaran; Jens Puschhof; Zvi Bentwich; Hagit Shapiro; Ido Amit; Hila Elinav; Eran Elinav

Diet-microbiome interactions in cancer 癌症中的饮食-微生物组相互作用

CANCER CELL

IF44.5

2025-04-01

PREAI

Abdeen, Suhaib K.; Mastandrea, Ignacio; Stinchcombe, Nina; Puschhof, Jens; Elinav, Eran

Modeling cancer-microbiome interactions in vitro: A guide to co-culture platforms 体外模拟癌症-微生物组相互作用: 共培养平台指南

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2024-12-23

OAAI

Moskal, Kamil; Khurana, Nimisha; Siegert, Luisa; Lee, Ye Seul; Clevers, Hans; Elinav, Eran; Puschhof, Jens

A comprehensive transcriptome characterization of individual nuclear receptor pathways in the human small intestine 人类小肠中单个核受体途径的全面转录组表征

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-10-30

OAAI

Willemsen, Sam; Yengej, Fjodor A. Yousef; Puschhof, Jens; Rookmaaker, Maarten B.; Verhaar, Marianne C.; van Es, Johan; Beumer, Joep; Clevers, Hans

Standardizing designed and emergent quantitative features in microphysiological systems

NATURE BIOMEDICAL ENGINEERING

IF26.6

2024-08-26

PREAI

Nahon, Dennis M.; Moerkens, Renee; Aydogmus, Hande; Lendemeijer, Bas; Martinez-Silgado, Adriana; Stein, Jeroen M.; Dostanic, Milica; Frimat, Jean-Philippe; Gontan, Cristina; de Graaf, Mees N. S.; Hu, Michel; Kasi, Dhanesh G.; Koch, Lena S.; Le, Kieu T. T.; Lim, Sangho; Middelkamp, Heleen H. T.; Mooiweer, Joram; Motreuil-Ragot, Paul; Niggl, Eva; Pleguezuelos-Manzano, Cayetano; Puschhof, Jens; Revyn, Nele; Rivera-Arbelaez, Jose M.; Slager, Jelle; Windt, Laura M.; Zakharova, Mariia; van Meer, Berend J.; Orlova, Valeria V.; de Vrij, Femke M. S.; Withoff, Sebo; Mastrangeli, Massimo; van der Meer, Andries D.; Mummery, Christine L.

Intracellular bacteria in cancer-prospects and debates 癌症中的细胞内细菌-前景和争论

NPJ BIOFILMS AND MICROBIOMES

IF9.2

2023-10-09

OAAI

Schorr, Lena; Mathies, Marius; Elinav, Eran; Puschhof, Jens

The microbial genotoxin colibactin exacerbates mismatch repair mutations in colorectal tumors 微生物基因毒素大肠杆菌素加剧了大肠肿瘤的错配修复突变

NEOPLASIA

IF7.7

2023-09-01

OAAI

Dougherty, Michael W.; Valdes-Mas, Rafael; Wernke, Kevin M.; Gharaibeh, Raad Z.; Yang, Ye; Brant, Jason O.; Riva, Alberto; Muehlbauer, Marcus; Elinav, Eran; Puschhof, Jens; Herzon, Seth B.; Jobin, Christian

Synthetic colibactins reveal the structural and biological mode-of-action of a microbial carcinogen

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Dougherty, Michael W.; Valdes-Mas, Rafael; Wernke, Kevin M.; Gharaibeh, Raad Z.; Riva, Alberto; Yang, Ye; Muehlbauer, Marcus; Elinav, Eran; Puschhof, Jens; Herzon, Seth B.; Jobin, Christian

Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation

NATURE IMMUNOLOGY

IF27.6

2023-03-20

PREAI

Zheng, Danping; Mohapatra, Gayatree; Kern, Lara; He, Yiming; Shmueli, Merav D.; Valdes-Mas, Rafael; Kolodziejczyk, Aleksandra A.; Prochnicki, Tomasz; Vasconcelos, Matilde B.; Schorr, Lena; Hertel, Franziska; Lee, Ye Seul; Rufino, Miguel Camacho; Ceddaha, Emmanuelle; Shimshy, Sandy; Hodgetts, Ryan James; Dori-Bachash, Mally; Kleimeyer, Christian; Goldenberg, Kim; Heinemann, Melina; Stettner, Noa; Harmelin, Alon; Shapiro, Hagit; Puschhof, Jens; Chen, Minhu; Flavell, Richard A.; Latz, Eicke; Merbl, Yifat; Abdeen, Suhaib K.; Elinav, Eran

Rapid tissue prototyping with micro-organospheres br

STEM CELL REPORTS

IF5.1

2022-09-01

OAAI

Wang, Zhaohui; Boretto, Matteo; Millen, Rosemary; Natesh, Naveen; Reckzeh, Elena S.; Hsu, Carolyn; Negrete, Marcos; Yao, Haipei; Quayle, William; Heaton, Brook E.; Harding, Alfred T.; Bose, Shree; Driehuis, Else; Beumer, Joep; Rivera, Grecia O.; van Ineveld, Ravian L.; Gex, Donald; DeVilla, Jessica; Wang, Daisong; Puschhof, Jens; Geurts, Maarten H.; Yeung, Athena; Hamele, Cait; Smith, Amber; Bankaitis, Eric; Xiang, Kun; Ding, Shengli; Nelson, Daniel; Delubac, Daniel; Rios, Anne; Abi-Hachem, Ralph; Jang, David; Goldstein, Bradley J.; Glass, Carolyn; Heaton, Nicholas S.; Hsu, David; Clevers, Hans; Shen, Xiling

Uncovering the mode of action of engineered T cells in patient cancer organoids 揭示工程改造的T细胞在患者癌症类器官中的作用方式

NATURE BIOTECHNOLOGY

IF41.7

2022-07-25

OAAI

Dekkers, Johanna F.; Alieva, Maria; Cleven, Astrid; Keramati, Farid; Wezenaar, Amber K. L.; van Vliet, Esmee J.; Puschhof, Jens; Brazda, Peter; Johanna, Inez; Meringa, Angelo D.; Rebel, Heggert G.; Buchholz, Maj-Britt; Roman, Mario Barrera; Zeeman, Amber L.; de Blank, Sam; Fasci, Domenico; Geurts, Maarten H.; Cornel, Annelisa M.; Driehuis, Else; Millen, Rosemary; Straetemans, Trudy; Nicolasen, Mara J. T.; Aarts-Riemens, Tineke; Ariese, Hendrikus C. R.; Johnson, Hannah R.; van Ineveld, Ravian L.; Karaiskaki, Froso; Kopper, Oded; Bar-Ephraim, Yotam E.; Kretzschmar, Kai; Eggermont, Alexander M. M.; Nierkens, Stefan; Wehrens, Ellen J.; Stunnenberg, Henk G.; Clevers, Hans; Kuball, Jurgen; Sebestyen, Zsolt; Rios, Anne C.

Colon Tumors in Enterotoxigenic Bacteroides fragilis (ETBF)-Colonized Mice Do Not Display a Unique Mutational Signature but Instead Possess Host-Dependent Alterations in the APC Gene 产肠毒素的脆弱拟杆菌 (ETBF) 定殖的小鼠中的结肠肿瘤不显示独特的突变特征，而是在APC基因中具有宿主依赖性的改变

MICROBIOLOGY SPECTRUM

IF3.8

2022-06-29

OAAI

Allen, Jawara; Huber, Axel Rosendahl; Pleguezuelos-Manzano, Cayetano; Puschhof, Jens; Wu, Shaoguang; Wu, Xinqun; Boot, Charelle; Saftien, Aurelia; O'Hagan, Heather M.; Wang, Hao; van Boxtel, Ruben; Clevers, Hans; Sears, Cynthia L.

BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell states

CELL REPORTS

IF6.9

2022-03-01

OAAI

Beumer, Joep; Puschhof, Jens; Yengej, Fjodor Yousef; Zhao, Lianzheng; Martinez-Silgado, Adriana; Blotenburg, Marloes; Begthel, Harry; Boot, Charelle; van Oudenaarden, Alexander; Chen, Ye-Guang; Clevers, Hans

A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium

NATURE COMMUNICATIONS

IF15.7

2021-12-09

OAAI

van der Linden, Franka H.; Mahlandt, Eike K.; Arts, Janine J. G.; Beumer, Joep; Puschhof, Jens; de Man, Saskia M. A.; Chertkova, Anna O.; Ponsioen, Bas; Clevers, Hans; van Buul, Jaap D.; Postma, Marten; Gadella, Theodorus W. J.; Goedhart, Joachim

A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses

NATURE COMMUNICATIONS

IF15.7

2021-09-17

OAAI

Beumer, Joep; Geurts, Maarten H.; Lamers, Mart M.; Puschhof, Jens; Zhang, Jingshu; van der Vaart, Jelte; Mykytyn, Anna Z.; Breugem, Tim, I; Riesebosch, Samra; Schipper, Debby; van den Doel, Petra B.; de Lau, Wim; Pleguezuelos-Manzano, Cayetano; Busslinger, Georg; Haagmans, Bart L.; Clevers, Hans

Intestinal organoid cocultures with microbes

NATURE PROTOCOLS

IF16

2021-08-11

129

OAAI

Puschhof, Jens; Pleguezuelos-Manzano, Cayetano; Martinez-Silgado, Adriana; Akkerman, Ninouk; Saftien, Aurelia; Boot, Charelle; de Waal, Amy; Beumer, Joep; Dutta, Devanjali; Heo, Inha; Clevers, Hans

A bacterial mutational footprint in colorectal cancer genomes

BRITISH JOURNAL OF CANCER

IF6.8

2021-03-19

OAAI

Rosendahl Huber, Axel; Pleguezuelos-Manzano, Cayetano; Puschhof, Jens

Derivation of snake venom gland organoids for in vitro venom production

NATURE PROTOCOLS

IF16

2021-01-27

PREAI

Puschhof, Jens; Post, Yorick; Beumer, Joep; Kerkkamp, Harald M.; Bittenbinder, Matyas; Vonk, Freek J.; Casewell, Nicholas R.; Richardson, Michael K.; Clevers, Hans

研究方向