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Andrew M. Waters

University of Cincinnati College of Medicine
H指数:18
被引数:3,013

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工作经历

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荣誉奖项

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Defining the MYC-regulated transcriptome and kinome that support KRAS- and ERK-dependent growth of pancreatic cancer

定义支持胰腺癌KRAS-和ERK依赖性生长的MYC调控转录组与激酶组

SCIENCE SIGNALING
IF6.6
2025-09-300
PRE
Hibshman, Priya S.; Stalnecker, Clint A.; Klomp, Jeffrey A.; Drizyte-Miller, Kristina; Klomp, Jennifer E.; Edwards, A. Cole; Pita, Lily M.; Hodge, Richard G.; Diehl, J. Nathaniel; Mouery, Ryan D.; Mouery, Brandon L.; Snare, Kayla R.; Waters, Andrew M.; Peng, Sen; Barker, Natalie K.; Pierobon, Mariaelena; Rashid, Naim U.; Tran, Nhan L.; Herring, Laura A.; Graves, Lee M.; Petricoin, Emanuel F.; Bryant, Kirsten L.; Cox, Adrienne D.; Der, Channing J.
Human pancreatic cancer single cell atlas reveals association of CXCL10 positive fibroblasts and basal subtype tumor cells
CANCER RESEARCH
IF16.6
2024-09-150
PRE
Loveless, Ian M.; Kempt, Samantha B.; Wu, Yuesong; Salas-Escabillas, Daniel J.; Hartway, Kailee; George, Madison; Makinwa, Yetunde; Stockdale, Thais; Zwernik, Samuel D.; Gartrelle, Kendyll; Reddy, Rohit G.; Long, Daniel; Wombell, Allison; Clark, Julie M.; Levin, Albert M.; Kwon, David; Huang, Ling; Francescone, Ralph; Vendramini-Costa, Debora B.; Stanger, Ben; Alessio, Adam; Waters, Andrew M.; Cui, Yuehua; Theisen, Brian; Crawford, Howard C.; Steele, Nina G.
Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers

介质激酶抑制阻碍转录可塑性并阻止KRAS突变癌症对ERK/MAPK靶向治疗的抗性

NPJ PRECISION ONCOLOGY
IF8
2024-05-312
OAAI
Nussbaum, Daniel P.; Martz, Colin A.; Waters, Andrew M.; Barrera, Alejandro; Liu, Annie; Rutter, Justine C.; Cerda-Smith, Christian G.; Stewart, Amy E.; Wu, Chao; Cakir, Merve; Levandowski, Cecilia B.; Kantrowitz, David E.; Mccall, Shannon J.; Pierobon, Mariaelena; Petricoin III, Emanuel F.; Joshua Smith, J.; Reddy, Timothy E.; Der, Channing J.; Taatjes, Dylan J.; Wood, Kris C.
TEAD Inhibition Overcomes YAP1/TAZ-Driven Primary and Acquired Resistance to KRASG12C Inhibitors

TEAD抑制克服了YAP1/TAZ驱动的对KRASG12C抑制剂的原发性和获得性抗性

CANCER RESEARCH
IF16.6
2023-11-0718
OA
Edwards, A. Cole; Stalnecker, Clint A.; Morales, Alexis Jean; Taylor, Khalilah E.; Klomp, Jennifer E.; Klomp, Jeffrey A.; Waters, Andrew M.; Sudhakar, Niranjan; Hallin, Jill; Tang, Tracy T.; Olson, Peter; Post, Leonard; Christensen, James G.; Cox, Adrienne D.; Der, Channing J.
Combination Therapies with CDK4/6 Inhibitors to Treat KRAS-Mutant Pancreatic Cancer

联合CDK4/6抑制剂治疗KRAS突变型胰腺癌

CANCER RESEARCH
IF16.6
2022-11-0857
OA
Goodwin, Craig M.; Waters, Andrew M.; Klomp, Jennifer E.; Javaid, Sehrish; Bryant, Kirsten L.; Stalnecker, Clint A.; Drizyte-Miller, Kristina; Papke, Bjoern; Yang, Runying; Amparo, Amber M.; Ozkan-Dagliyan, Irem; Baldelli, Elisa; Calvert, Valerie; Pierobon, Mariaelena; Sorrentino, Jessica A.; Beelen, Andrew P.; Bublitz, Natalie; Luethen, Mareen; Wood, Kris C.; Petricoin III, Emanuel F.; Sers, Christine; McRee, Autumn J.; Cox, Adrienne D.; Der, Channing J.
Functional and biological heterogeneity of KRASQ61 mutations

KRASQ61突变的功能和生物学异质性

SCIENCE SIGNALING
IF6.6
2022-08-0915
OA
Huynh, Minh, V; Hobbs, G. Aaron; Schaefer, Antje; Pierobon, Mariaelena; Carey, Leiah M.; Diehl, J. Nathaniel; DeLiberty, Jonathan M.; Thurman, Ryan D.; Cooke, Adelaide R.; Goodwin, Craig M.; Cook, Joshua H.; Lin, Lin; Waters, Andrew M.; Rashid, Naim U.; Petricoin, Emanuel F., III; Campbell, Sharon L.; Haigis, Kevin M.; Simeone, Diane M.; Lyssiotis, Costas A.; Cox, Adrienne D.; Der, Channing J.
Concurrent Inhibition of ERK and Farnesyltransferase Suppresses the Growth of HRAS Mutant Head and Neck Squamous Cell Carcinoma

同时抑制ERK和法尼基转移酶抑制HRAS突变型头颈部鳞状细胞癌的生长

MOLECULAR CANCER THERAPEUTICS
IF5.5
2022-02-2814
OA
Javaid, Sehrish; Schaefer, Antje; Goodwin, Craig M.; Nguyen, Victoria V.; Massey, Frances L.; Pierobon, Mariaelena; Gambrell-Sanders, Da'jhnae; Waters, Andrew M.; Lambert, Kathryn N.; Diehl, J. Nathaniel; Hobbs, G. Aaron; Wood, Kris C.; Petricoin, Emanuel F., III; Der, Channing J.; Cox, Adrienne D.
Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth

ECT2的异常表达和亚细胞定位驱动结直肠癌的进展和生长

CANCER RESEARCH
IF16.6
2022-01-0423
OA
Cook, Danielle R.; Kang, Melissa; Martin, Timothy D.; Galanko, Joseph A.; Loeza, Gabriela H.; Trembath, Dimitri G.; Justilien, Verline; Pickering, Karen A.; Vincent, David F.; Jarosch, Armin; Jurmeister, Philipp; Waters, Andrew M.; Hibshman, Priya S.; Campbell, Andrew D.; Ford, Catriona A.; Keku, Temitope O.; Yeh, Jen Jen; Lee, Michael S.; Cox, Adrienne D.; Fields, Alan P.; Sandler, Robert S.; Sansom, Owen J.; Sers, Christine; Schaefer, Antje; Der, Channing J.
CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment

CHK1保护致癌KRAS表达细胞免受DNA损伤，是胰腺癌治疗的靶点

CELL REPORTS
IF6.9
2021-11-0123
OAAI
Klomp, Jennifer E.; Lee, Ye S.; Goodwin, Craig M.; Papke, Bjorn; Klomp, Jeff A.; Waters, Andrew M.; Stalnecker, Clint A.; DeLiberty, Jonathan M.; Drizyte-Miller, Kristina; Yang, Runying; Diehl, J. Nathaniel; Yin, Hongwei H.; Pierobon, Mariaelena; Baldelli, Elisa; Ryan, Meagan B.; Li, Siqi; Peterson, Jackson; Smith, Amber R.; Neal, James T.; McCormick, Aaron K.; Kuo, Calvin J.; Counter, Christopher M.; Petricoin, Emanuel F.; Cox, Adrienne D.; Bryant, Kirsten L.; Der, Channing J.
Targeting p130Cas-and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition

靶向p130Cas-and微管依赖的MYC调节使胰腺癌对ERK MAPK抑制敏感

CELL REPORTS
IF6.9
2021-06-0118
OAAI
Waters, Andrew M.; Khatib, Tala O.; Papke, Bjoern; Goodwin, Craig M.; Hobbs, G. Aaron; Diehl, J. Nathaniel; Yang, Runying; Edwards, A. Cole; Walsh, Katherine H.; Sulahian, Rita; McFarland, James M.; Kapner, Kevin S.; Gilbert, Thomas S. K.; Stalnecker, Clint A.; Javaid, Sehrish; Barkovskaya, Anna; Grover, Kajal R.; Hibshman, Priya S.; Blake, Devon R.; Schaefer, Antje; Nowak, Katherine M.; Klomp, Jennifer E.; Hayes, Tikvah K.; Kassner, Michelle; Tang, Nanyun; Tanaseichuk, Olga; Chen, Kaisheng; Zhou, Yingyao; Kalkat, Manpreet; Herring, Laura E.; Graves, Lee M.; Penn, Linda Z.; Yin, Hongwei H.; Aguirre, Andrew J.; Hahn, William C.; Cox, Adrienne D.; Der, Channing J.
Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers

Raf-mek-erk级联的低剂量垂直抑制导致KRAS突变型癌症的凋亡死亡

CELL REPORTS
IF6.9
2020-06-0171
OAAI
Ozkan-Dagliyan, Irem; Diehl, J. Nathaniel; George, Samuel D.; Schaefer, Antje; Papke, Bjoern; Klotz-Noack, Kathleen; Waters, Andrew M.; Goodwin, Craig M.; Gautam, Prson; Pierobon, Mariaelena; Peng, Sen; Gilbert, Thomas S. K.; Lin, Kevin H.; Dagliyan, Onur; Wennerberg, Krister; Petricoin, Emanuel F., III; Tran, Nhan L.; Bhagwat, Shripad, V; Tiu, Ramon, V; Peng, Sheng-Bin; Herring, Laura E.; Graves, Lee M.; Sers, Christine; Wood, Kris C.; Cox, Adrienne D.; Der, Channing J.
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer (vol 25, pg 628, 2019)

ERK和自噬抑制的组合作为胰腺癌的治疗方法 (第25卷，628页，2019)

NATURE MEDICINE
IF50
2020-06-0117
OAAI
Bryant, Kirsten L.; Stalnecker, Clint A.; Zeitouni, Daniel; Klomp, Jennifer E.; Peng, Sen; Tikunov, Andrey P.; Gunda, Venugopal; Pierobon, Mariaelena; Waters, Andrew M.; George, Samuel D.; Tomar, Garima; Papke, Bjorn; Hobbs, G. Aaron; Yan, Liang; Hayes, Tikvah K.; Diehl, J. Nathaniel; Goode, Gennifer D.; Chaika, Nina V.; Wang, Yingxue; Zhang, Guo-Fang; Witkiewicz, Agnieszka K.; Knudsen, Erik S.; Petricoin, Emanuel F., III; Singh, Pankaj K.; Macdonald, Jeffrey M.; Tran, Nhan L.; Lyssiotis, Costas A.; Ying, Haoqiang; Kimmelman, Alec C.; Cox, Adrienne D.; Der, Channing J.
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer

非典型KRASG12R突变体在胰腺癌的PI3K信号传导和巨胞饮作用中受损

CANCER DISCOVERY
IF33.3
2020-01-09139
OAAI
Hobbs, G. Aaron; Baker, Nicole M.; Miermont, Anne M.; Thurman, Ryan D.; Pierobon, Mariaelena; Tran, Timothy H.; Anderson, Andrew O.; Waters, Andrew M.; Diehl, J. Nathaniel; Papke, Bjoern; Hodge, Richard G.; Klomp, Jennifer E.; Goodwin, Craig M.; DeLiberty, Jonathan M.; Wang, Junning; Ng, Raymond W. S.; Gautam, Prson; Bryant, Kirsten L.; Esposito, Dominic; Campbell, Sharon L.; Petricoin, Emanuel F., III; Simanshu, Dhirendra K.; Aguirre, Andrew J.; Wolpin, Brian M.; Wennerberg, Krister; Rudloff, Udo; Cox, Adrienne D.; Der, Channing J.

研究方向

暂未获取到该数据
C
Channing J. Der
H 指数:127论文数:1,046被引数:7.1万
A
Adrienne D. Cox
H 指数:73论文数:517被引数:1.9万
M
Mariaelena Pierobon
H 指数:39论文数:385被引数:7,080
C
Craig M. Goodwin
H 指数:15论文数:153被引数:1,633
C
Clint A. Stalnecker
H 指数:17论文数:211被引数:4,403
J
J. Nathaniel Diehl
H 指数:18论文数:49被引数:1,837
E
Emanuel F. Petricoin
H 指数:81论文数:627被引数:2.8万
B
Bjoern Papke
H 指数:16论文数:134被引数:2,983
J
Jennifer E. Klomp
H 指数:20论文数:153被引数:2,384
K
Kirsten L. Bryant
H 指数:20论文数:200被引数:3,508