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G

G. Aaron Hobbs

Medical University of South Carolina
H指数:21
被引数:5,992

个人简介

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教育背景

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工作经历

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荣誉奖项

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Secreted frizzled-related protein 2 monoclonal antibody-mediated IFN-ϒ reprograms tumor-associated macrophages to suppress triple negative breast cancer

分泌性卷曲相关蛋白2单克隆抗体介导的IFN-ϒ重编程肿瘤相关巨噬细胞以抑制三阴性乳腺癌

Breast Cancer Research
IF5.6
2025-12-050
OAAI
Lillian Hsu; Julie Siegel; Patrick Nasarre; Nathaniel Oberholtzer; Rupak Mukherjee; Eleanor Hilliard; Paramita Chakraborty; Rachel A. Burge; Elizabeth C. O’Quinn; Olivia Sweatt; Mohamed Faisal Kassir; G. Aaron Hobbs; Michael Ostrowski; Ann-Marie Broome; Shikhar Mehrotra; Nancy Klauber-DeMore
HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer
CELL DEATH AND DIFFERENTIATION
IF15.4
2024-05-282
OAAI
Ferretti, Giulia D. S.; Quaas, Colleen E.; Bertolini, Irene; Zuccotti, Alessandro; Saatci, Ozge; Kashatus, Jennifer A.; Sharmin, Salma; Lu, David Y.; Poli, Adi Narayana Reddy; Quesnelle, Abigail F.; Rodriguez-Blanco, Jezabel; de Cubas, Aguirre A.; Hobbs, G. Aaron; Liu, Qin; O'Bryan, John P.; Salvino, Joseph M.; Kashatus, David F.; Sahin, Ozgur; Barnoud, Thibaut
Functional and biological heterogeneity of KRASQ61 mutations

KRASQ61突变的功能和生物学异质性

SCIENCE SIGNALING
IF6.6
2022-08-0915
OA
Huynh, Minh, V; Hobbs, G. Aaron; Schaefer, Antje; Pierobon, Mariaelena; Carey, Leiah M.; Diehl, J. Nathaniel; DeLiberty, Jonathan M.; Thurman, Ryan D.; Cooke, Adelaide R.; Goodwin, Craig M.; Cook, Joshua H.; Lin, Lin; Waters, Andrew M.; Rashid, Naim U.; Petricoin, Emanuel F., III; Campbell, Sharon L.; Haigis, Kevin M.; Simeone, Diane M.; Lyssiotis, Costas A.; Cox, Adrienne D.; Der, Channing J.
STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer
LIFE SCIENCE ALLIANCE
IF2.9
2022-07-0826
OAAI
Lefler, Julia E.; MarElia-Bennett, Catherine B.; Thies, Katie A.; Hildreth, Blake E., III; Sharma, Sudarshana M.; Pitarresi, Jason R.; Han, Lu; Everett, Caroline; Koivisto, Christopher; Cuitino, Maria C.; Timmers, Cynthia; O'Quinn, Elizabeth; Parrish, Melodie; Romeo, Martin J.; Linke, Amanda J.; Hobbs, G. Aaron; Leone, Gustavo; Guttridge, Denis C.; Zimmers, Teresa A.; Lesinski, Gregory B.; Ostrowski, Michael C.
Concurrent Inhibition of ERK and Farnesyltransferase Suppresses the Growth of HRAS Mutant Head and Neck Squamous Cell Carcinoma

同时抑制ERK和法尼基转移酶抑制HRAS突变型头颈部鳞状细胞癌的生长

MOLECULAR CANCER THERAPEUTICS
IF5.5
2022-02-2814
OA
Javaid, Sehrish; Schaefer, Antje; Goodwin, Craig M.; Nguyen, Victoria V.; Massey, Frances L.; Pierobon, Mariaelena; Gambrell-Sanders, Da'jhnae; Waters, Andrew M.; Lambert, Kathryn N.; Diehl, J. Nathaniel; Hobbs, G. Aaron; Wood, Kris C.; Petricoin, Emanuel F., III; Der, Channing J.; Cox, Adrienne D.
Targeting p130Cas-and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition

靶向p130Cas-and微管依赖的MYC调节使胰腺癌对ERK MAPK抑制敏感

CELL REPORTS
IF6.9
2021-06-0118
OAAI
Waters, Andrew M.; Khatib, Tala O.; Papke, Bjoern; Goodwin, Craig M.; Hobbs, G. Aaron; Diehl, J. Nathaniel; Yang, Runying; Edwards, A. Cole; Walsh, Katherine H.; Sulahian, Rita; McFarland, James M.; Kapner, Kevin S.; Gilbert, Thomas S. K.; Stalnecker, Clint A.; Javaid, Sehrish; Barkovskaya, Anna; Grover, Kajal R.; Hibshman, Priya S.; Blake, Devon R.; Schaefer, Antje; Nowak, Katherine M.; Klomp, Jennifer E.; Hayes, Tikvah K.; Kassner, Michelle; Tang, Nanyun; Tanaseichuk, Olga; Chen, Kaisheng; Zhou, Yingyao; Kalkat, Manpreet; Herring, Laura E.; Graves, Lee M.; Penn, Linda Z.; Yin, Hongwei H.; Aguirre, Andrew J.; Hahn, William C.; Cox, Adrienne D.; Der, Channing J.
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer (vol 25, pg 628, 2019)

ERK和自噬抑制的组合作为胰腺癌的治疗方法 (第25卷，628页，2019)

NATURE MEDICINE
IF50
2020-06-0117
OAAI
Bryant, Kirsten L.; Stalnecker, Clint A.; Zeitouni, Daniel; Klomp, Jennifer E.; Peng, Sen; Tikunov, Andrey P.; Gunda, Venugopal; Pierobon, Mariaelena; Waters, Andrew M.; George, Samuel D.; Tomar, Garima; Papke, Bjorn; Hobbs, G. Aaron; Yan, Liang; Hayes, Tikvah K.; Diehl, J. Nathaniel; Goode, Gennifer D.; Chaika, Nina V.; Wang, Yingxue; Zhang, Guo-Fang; Witkiewicz, Agnieszka K.; Knudsen, Erik S.; Petricoin, Emanuel F., III; Singh, Pankaj K.; Macdonald, Jeffrey M.; Tran, Nhan L.; Lyssiotis, Costas A.; Ying, Haoqiang; Kimmelman, Alec C.; Cox, Adrienne D.; Der, Channing J.
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer

非典型KRASG12R突变体在胰腺癌的PI3K信号传导和巨胞饮作用中受损

CANCER DISCOVERY
IF33.3
2020-01-09139
OAAI
Hobbs, G. Aaron; Baker, Nicole M.; Miermont, Anne M.; Thurman, Ryan D.; Pierobon, Mariaelena; Tran, Timothy H.; Anderson, Andrew O.; Waters, Andrew M.; Diehl, J. Nathaniel; Papke, Bjoern; Hodge, Richard G.; Klomp, Jennifer E.; Goodwin, Craig M.; DeLiberty, Jonathan M.; Wang, Junning; Ng, Raymond W. S.; Gautam, Prson; Bryant, Kirsten L.; Esposito, Dominic; Campbell, Sharon L.; Petricoin, Emanuel F., III; Simanshu, Dhirendra K.; Aguirre, Andrew J.; Wolpin, Brian M.; Wennerberg, Krister; Rudloff, Udo; Cox, Adrienne D.; Der, Channing J.
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

ERK联合自噬抑制治疗胰腺癌的研究进展

NATURE MEDICINE
IF50
2019-03-04526
OAAI
Bryant, Kirsten L.; Stalnecker, Clint A.; Zeitouni, Daniel; Klomp, Jennifer E.; Peng, Sen; Tikunov, Andrey P.; Gunda, Venugopal; Pierobon, Mariaelena; Waters, Andrew M.; George, Samuel D.; Tomar, Garima; Papke, Bjorn; Hobbs, G. Aaron; Yan, Liang; Hayes, Tikvah K.; Diehl, J. Nathaniel; Goode, Gennifer D.; Chaika, Nina V.; Wang, Yingxue; Zhang, Guo-Fang; Witkiewicz, Agnieszka K.; Knudsen, Erik S.; Petricoin, Emanuel F., III; Singh, Pankaj K.; Macdonald, Jeffrey M.; Tran, Nhan L.; Lyssiotis, Costas A.; Ying, Haoqiang; Kimmelman, Alec C.; Cox, Adrienne D.; Der, Channing J.
Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies

评估同工型和突变特异性RAS抗体的选择性和敏感性

SCIENCE SIGNALING
IF6.6
2017-09-2652
OAAI
Waters, Andrew M.; Ozkan-Dagliyan, Irem; Vaseva, Angelina V.; Fer, Nicole; Strathern, Leslie A.; Hobbs, G. Aaron; Tessier-Cloutier, Basile; Gillette, William K.; Bagni, Rachel; Whiteley, Gordon R.; Hartley, James L.; McCormick, Frank; Cox, Adrienne D.; Houghton, Peter J.; Huntsman, David G.; Philips, Mark R.; Der, Channing J.

研究方向

暂未获取到该数据
C
Channing J. Der
H 指数:127论文数:1,046被引数:7.1万
A
Adrienne D. Cox
H 指数:73论文数:517被引数:1.9万
A
Andrew M. Waters
H 指数:18论文数:348被引数:3,057
J
J. Nathaniel Diehl
H 指数:18论文数:49被引数:1,859
S
Sharon L. Campbell
H 指数:62论文数:263被引数:1.2万
M
Mariaelena Pierobon
H 指数:39论文数:385被引数:7,149
J
John P. O’Bryan
H 指数:38论文数:123被引数:5,170
C
Craig M. Goodwin
H 指数:15论文数:153被引数:1,659
E
Emanuel F. Petricoin
H 指数:81论文数:627被引数:2.8万
A
Antje Schaefer
H 指数:22论文数:79被引数:1,626