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C

Christopher B. Cooper

global alliance for tb drug development
H指数:28
被引数:2,238

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Thioquinazolinones as Antituberculosis Agents Targeting Phosphopantetheinyl Transferase

噻唑并[3,2-a]喹唑啉酮类化合物作为靶向磷脂泛酰巯基乙胺转移酶的抗结核药物

Journal of Medicinal Chemistry
IF6.8
2025-07-010
PRE
Amrita Singh; Logan T. Zwerneman; Kyle Planck; Takushi Kaneko; Andrew J. Perkowski; Christine M. Suh; Alexander Alex; James Bean; Kristin Burns-Huang; David Zhang; Helena I. M. Boshoff; Christine Roubert; Inna Krieger; Mark Gardner; Bastien Cautain; Christopher B. Cooper; Zaid Tanvir; James Sacchettini; Ben S. Gold; Kyu Y. Rhee; Nader Fotouhi; Carl F. Nathan; Jeffrey Aubé
Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase
SCIENCE ADVANCES
IF12.5
2024-03-151
OAAI
Singh, Amrita; Ottavi, Samantha; Krieger, Inna; Planck, Kyle; Perkowski, Andrew; Kaneko, Takushi; Davis, Andrew M.; Suh, Christine; Zhang, David; Goullieux, Laurent; Alex, Alexander; Roubert, Christine; Gardner, Mark; Preston, Marian; Smith, Dave M.; Ling, Yan; Roberts, Julia; Cautain, Bastien; Upton, Anna; Cooper, Christopher B.; Serbina, Natalya; Tanvir, Zaid; Mosior, John; Ouerfelli, Ouathek; Yang, Guangli; Gold, Ben S.; Rhee, Kyu Y.; Sacchettini, James C.; Fotouhi, Nader; Aube, Jeffrey; Nathan, Carl
Synthesis and structure-activity relationships for a new class of tetrahydronaphthalene amide inhibitors of Mycobacterium tuberculosis

新型结核分枝杆菌四氢萘酰胺类抑制剂的合成及构效关系

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2022-02-019
OAAI
Sutherland, Hamish S. S.; Lu, Guo-Liang; Tong, Amy S. T. G.; Conole, Daniel M.; Franzblau, Scott G. U.; Upton, Anna B.; Lotlikar, Manisha U. D.; Cooper, Christopher B. J.; Palmer, Brian D. A.; Choi, Peter J.; Denny, William A.
The Tuberculosis Drug Accelerator at year 10: what have we learned?
NATURE MEDICINE
IF50
2021-07-0539
OAAI
Aldridge, Bree B.; Barros-Aguirre, David; Barry, Clifton E., III; Bates, Robert H.; Berthel, Steven J.; Boshoff, Helena I.; Chibale, Kelly; Chu, Xin-Jie; Cooper, Christopher B.; Dartois, Veronique; Duncan, Ken; Fotouhi, Nader; Gusovsky, Fabian; Hipskind, Philip A.; Kempf, Dale J.; Lelievre, Joel; Lenaerts, Anne J.; McNamara, Case W.; Mizrahi, Valerie; Nathan, Carl; Olsen, David B.; Parish, Tanya; Petrassi, H. Michael; Pym, Alexander; Rhee, Kyu Y.; Robertson, Gregory T.; Rock, Jeremy Michael; Rubin, Eric J.; Russell, Betsy; Russell, David G.; Sacchettini, James C.; Schnappinger, Dirk; Schrimpf, Michael; Upton, Anna M.; Warner, Peter; Wyatt, Paul Graham; Yuan, Ying
Novel Linker Variants of Antileishmanial/Antitubercular 7-Substituted 2-Nitroimidazooxazines Offer Enhanced Solubility

抗利什曼/抗结核7-取代的2-硝基咪唑并恶嗪的新型接头变体提供了增强的溶解度

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2021-01-2110
OA
Thompson, Andrew M.; O'Connor, Patrick D.; Yardley, Vanessa; Maes, Louis; Launay, Delphine; Braillard, Stephanie; Chatelain, Eric; Wan, Baojie; Franzblau, Scott G.; Ma, Zhenkun; Cooper, Christopher B.; Denny, William A.
Scaffold Morphing To Identify Novel DprE1 Inhibitors with Antimycobacterial Activity

支架变形以鉴定具有抗分枝杆菌活性的新型DprE1抑制剂

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2019-09-2330
OAAI
Manjunatha, M. R.; Shandil, Radha; Panda, Manoranjan; Sadler, Claire; Ambady, Anisha; Panduga, Vijender; Kumar, Naveen; Mahadevaswamy, Jyothi; Sreenivasaiah, M.; Narayan, Ashwini; Guptha, Supreeth; Sharma, Sreevalli; Sambandamurthy, Vasan K.; Ramachandran, Vasanthi; Mallya, Meenakshi; Cooper, Christopher; Mdluli, Khisi; Butler, Scott; Tommasi, Ruben; Iyer, Pravin S.; Narayanan, Shridhar; Chatterji, Monalisa; Shirude, Pravin S.
3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel

贝达喹啉的3，5-二烷氧基吡啶类似物是有效的抗结核药，对hERG通道的抑制作用最小

BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2019-04-0186
OAAI
Sutherland, Hamish S.; Tong, Amy S. T.; Choi, Peter J.; Blaser, Adrian; Conole, Daniel; Franzblau, Scott G.; Lotlikar, Manisha U.; Cooper, Christopher B.; Upton, Anna M.; Denny, William A.; Palmer, Brian D.

研究方向

暂未获取到该数据
W
William A. Denny
H 指数:84论文数:868被引数:2.6万
S
Scott G. Franzblau
H 指数:77论文数:518被引数:2.1万
A
Anna M. Upton
H 指数:30论文数:65被引数:2,870
P
Peter J. Choi
H 指数:14论文数:42被引数:758
B
Brian D. Palmer
H 指数:51论文数:262被引数:8,408
H
Hamish S. Sutherland
H 指数:17论文数:59被引数:1,162
A
Amy S.T. Tong
H 指数:9论文数:19被引数:476
Z
Zhenkun Ma
H 指数:40论文数:146被引数:4,759
A
Adrian Blaser
H 指数:22论文数:37被引数:1,594
D
Daniel Conole
H 指数:18论文数:47被引数:1,037