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H

Hirotaka Tomiyasu

The University of Tokyo
H指数:17
被引数:926

个人简介

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教育背景

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工作经历

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荣誉奖项

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Identification of Novel Therapeutic Agent Candidates Through High Throughput Screening With Chemical Library Based on Molecular Subclassification in Canine Histiocytic Sarcoma Cell Lines

通过基于犬组织细胞肉瘤细胞系的分子亚分类，利用化学文库进行高通量筛选以鉴定新型治疗剂候选物

Veterinary and Comparative Oncology
IF1.9
2026-09-010
OAAI
Sakuma, Hiroki; Tomiyasu, Hirotaka; Takamiya, Mari; Goto-Koshino, Yuko; Tsukamoto, Atsushi; Bonkobara, Makoto; Okuda, Masaru
Characterization of putative germline pathogenic variants in 27 candidate cancer-predisposing genes in 813 cats using a feline-specific multiplex targeted sequencing

利用猫特异性多重靶向测序技术对813只猫中27个候选癌症易感基因的潜在生殖系致病性变异进行表征

Scientific Reports
IF3.9
2026-08-080
OA
Namiko Ikeda; Keijiro Mizukami; Ryoko Yamada; Hiroto Toyoda; Tomomi Aoi; Mikiko Endo; Yusuke Iwasaki; Daiki Kato; Takayuki Nakagawa; Ryohei Nishimura; Hirotaka Tomiyasu; Yukihide Momozawa
Genetic variants of flavin-containing monooxygenase (FMO) 1 and FMO3 in 5887 dogs influenced oxygenations of probe substrates benzydamine, trimethylamine, and methyl p-tolyl sulfide

5887只狗中，黄素单加氧酶（FMO）1和FMO3的遗传变异影响了探针底物苯茚胺、三甲胺和对甲苯硫醚的氧化反应。

Biochemical Pharmacology
IF5.6
2026-02-100
PRE
Yasuhiro Uno; Koya Fukunaga; Makiko Shimizu; Genki Ushirozako; Keijiro Mizukami; Tomomi Aoi; Hirotaka Tomiyasu; Muneki Honnami; Hajime Tsujimoto; Masahiro Sakaguchi; Masaharu Hisasue; Taisei Mushiroda; Yukihide Momozawa; Hiroshi Yamazaki
In response to 'Factors associated with the development of gastrointestinal adverse events in dogs with multicentric lymphoma treated with CHOP or CEOP-based protocols: a multi-institutional, retrospective study' by Treggiari et al.

作为Treggiari等人发表的题为“Factors associated with the development of gastrointestinal adverse events in dogs with multicentric lymphoma treated with CHOP or CEOP-based protocols: a multi-institutional, retrospective study”的论文的回应。

JOURNAL OF SMALL ANIMAL PRACTICE
IF1.9
2025-11-010
PRE
Ohmi, A.; Motegi, T.; Tomiyasu, H.; Okuda, M.
Genetic variants in dog cytochrome P450 2B6 and their relevance to inter-individual variability of oxidations of probe drug propofol

犬细胞色素P450 2B6的遗传变异及其与探针药物丙泊酚氧化反应个体间变异的相关性

Drug Metabolism and Disposition
IF4
2025-10-300
PRE
Yasuhiro Uno; Koya Fukunaga; Genki Ushirozako; Norie Murayama; Keijiro Mizukami; Tomomi Aoi; Hirotaka Tomiyasu; Muneki Honnami; Hajime Tsujimoto; Masahiro Sakaguchi; Masaharu Hisasue; Taisei Mushiroda; Yukihide Momozawa; Hiroshi Yamazaki
Genetic variants of cytochrome P450 2C21 identified by screening 6344 dogs influenced oxidations of the probe drug omeprazole

通过筛查6344只狗，鉴定出的细胞色素P450 2C21基因变异体影响了探针药物奥美拉唑的氧化作用。

Biochemical Pharmacology
IF5.6
2025-10-030
PRE
Yasuhiro Uno; Koya Fukunaga; Genki Ushirozako; Norie Murayama; Keijiro Mizukami; Tomomi Aoi; Hirotaka Tomiyasu; Muneki Honnami; Hajime Tsujimoto; Masahiro Sakaguchi; Masaharu Hisasue; Taisei Mushiroda; Yukihide Momozawa; Hiroshi Yamazaki
Whole exome and transcriptome analysis revealed the activation of ERK and Akt signaling pathway in canine histiocytic sarcoma
SCIENTIFIC REPORTS
IF3.9
2023-05-255
OAAI
Asada, Hajime; Tani, Akiyoshi; Sakuma, Hiroki; Hirabayashi, Miyuki; Matsumoto, Yuki; Watanabe, Kei; Tsuboi, Masaya; Yoshida, Shino; Harada, Kei; Uchikai, Takao; Goto-Koshino, Yuko; Chambers, James K.; Ishihara, Genki; Kobayashi, Tetsuya; Irie, Mitsuhiro; Uchida, Kazuyuki; Ohno, Koichi; Bonkobara, Makoto; Tsujimoto, Hajime; Tomiyasu, Hirotaka
Development of an exosomal gene signature to detect residual disease in dogs with osteosarcoma using a novel xenograft platform and machine learning
LABORATORY INVESTIGATION
IF4.2
2021-12-016
OAAI
Makielski, Kelly M.; Donnelly, Alicia J.; Khammanivong, Ali; Scott, Milcah C.; Ortiz, Andrea R.; Galvan, Dana C.; Tomiyasu, Hirotaka; Amaya, Clarissa; Ward, Kristi; Montoya, Alexa; Garbe, John R.; Mills, Lauren J.; Cutter, Gary R.; Fenger, Joelle M.; Kisseberth, William C.; O'Brien, Timothy D.; Weigel, Brenda J.; Spector, Logan G.; Bryan, Brad A.; Subramanian, Subbaya; Modiano, Jaime F.

研究方向

暂未获取到该数据
J
James Chambers
H 指数:32论文数:484被引数:4,430
K
Keijiro Mizukami
H 指数:18论文数:75被引数:1,304
T
Tomomi Aoi
H 指数:8论文数:37被引数:622
J
Jaime F. Modiano
H 指数:52论文数:409被引数:8,561
M
Milcah C. Scott
H 指数:19论文数:87被引数:2,264
H
Hajime Tsujimoto
H 指数:49论文数:500被引数:1.0万
S
Subbaya Subramanian
H 指数:56论文数:293被引数:1.0万
K
Koya Fukunaga
H 指数:16论文数:52被引数:730
Y
Yasuhiro Uno
H 指数:29论文数:212被引数:3,040
H
Hiroshi Yamazaki
H 指数:74论文数:1,105被引数:2.7万