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A

Annabelle Lewis

University of Oxford
H指数:24
被引数:3,233

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Addendum: Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche

补充：异常的上皮GREM1表达从干细胞微环境外的细胞启动结肠肿瘤发生

Nature Medicine
IF50
2026-10-090
PRE
Hayley Davis; Shazia Irshad; Mukesh Bansal; Hannah Rafferty; Tatjana Boitsova; Chiara Bardella; Emma Jaeger; Annabelle Lewis; Luke Freeman-Mills; Francesc C. Giner; Pedro Rodenas-Cuadrado; Sreelakshmi Mallappa; Susan Clark; Huw Thomas; Rosemary Jeffery; Richard Poulsom; Manuel Rodriguez-Justo; Marco Novelli; Runjan Chetty; Andrew Silver; Owen J. Sansom; Florian R. Greten; Lai Mun Wang; James E. East; Ian Tomlinson; Simon J. Leedham
The polymorphic variant rs1800734 influences methylation acquisition and allele-specific TFAP4 binding in the MLH1 promoter leading to differential mRNA expression
SCIENTIFIC REPORTS
IF3.9
2019-09-178
OAAI
Thomas, Rachael; Trapani, Davide; Goodyer-Sait, Lily; Tomkova, Marketa; Fernandez-Rozadilla, Ceres; Sahnane, Nora; Woolley, Connor; Davis, Hayley; Chegwidden, Laura; Kriaucionis, Skirmantas; Maughan, Timothy; Leedham, Simon; Palles, Claire; Furlan, Daniela; Tomlinson, Ian; Lewis, Annabelle
Bone morphogenetic protein and Notch signalling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer

预后不良，间充质亚型结直肠癌中的骨形态发生蛋白和Notch信号串扰

JOURNAL OF PATHOLOGY
IF5.2
2017-05-0343
OAAI
Irshad, Shazia; Bansal, Mukesh; Guarnieri, Paolo; Davis, Hayley; Zen, Ayman Al Haj; Baran, Brygida; Pinna, Claudia Maria Assunta; Rahman, Haseeb; Biswas, Sujata; Bardella, Chiara; Jeffery, Rosemary; Wang, Lai Mun; East, James Edward; Tomlinson, Ian; Lewis, Annabelle; Leedham, Simon John
Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche
NATURE MEDICINE
IF50
2014-12-01201
OAAI
Davis, Hayley; Irshad, Shazia; Bansal, Mukesh; Rafferty, Hannah; Boitsova, Tatjana; Bardella, Chiara; Jaeger, Emma; Lewis, Annabelle; Freeman-Mills, Luke; Giner, Francesc C.; Rodenas-Cuadrado, Pedro; Mallappa, Sreelakshmi; Clark, Susan; Thomas, Huw; Jeffery, Rosemary; Poulsom, Richard; Rodriguez-Justo, Manuel; Novelli, Marco; Chetty, Runjan; Silver, Andrew; Sansom, Owen J.; Greten, Florian R.; Wang, Lai Mun; East, James E.; Tomlinson, Ian; Leedham, Simon J.
Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer
PLOS GENETICS
IF3.7
2011-06-02192
OAAI
Tomlinson, Ian P. M.; Carvajal-Carmona, Luis G.; Dobbins, Sara E.; Tenesa, Albert; Jones, Angela M.; Howarth, Kimberley; Palles, Claire; Broderick, Peter; Jaeger, Emma E. M.; Farrington, Susan; Lewis, Annabelle; Prendergast, James G. D.; Pittman, Alan M.; Theodoratou, Evropi; Olver, Bianca; Walker, Marion; Penegar, Steven; Barclay, Ella; Whiffin, Nicola; Martin, Lynn; Ballereau, Stephane; Lloyd, Amy; Gorman, Maggie; Lubbe, Steven; Howie, Bryan; Marchini, Jonathan; Ruiz-Ponte, Clara; Fernandez-Rozadilla, Ceres; Castells, Antoni; Carracedo, Angel; Castellvi-Bel, Sergi; Duggan, David; Conti, David; Cazier, Jean-Baptiste; Campbell, Harry; Sieber, Oliver; Lipton, Lara; Gibbs, Peter; Martin, Nicholas G.; Montgomery, Grant W.; Young, Joanne; Baird, Paul N.; Gallinger, Steven; Newcomb, Polly; Hopper, John; Jenkins, Mark A.; Aaltonen, Lauri A.; Kerr, David J.; Cheadle, Jeremy; Pharoah, Paul; Casey, Graham; Houlston, Richard S.; Dunlop, Malcolm G.
FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation

FBXW7影响小鼠肠道稳态和癌症，靶向Notch，6月和DEK降解

JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2011-01-31163
OAAI
Babaei-Jadidi, Roya; Li, Ningning; Saadeddin, Anas; Spencer-Dene, Bradley; Jandke, Anett; Muhammad, Belal; Ibrahim, ElSayed E.; Muraleedharan, Ranjithmenon; Abuzinadah, Mohammed; Davis, Hayley; Lewis, Annabelle; Watson, Susan; Behrens, Axel; Tomlinson, Ian; Nateri, Abdolrahman Shams

研究方向

暂未获取到该数据
I
Ian Tomlinson
H 指数:129论文数:1,284被引数:6.1万
H
Hayley L. Belnoue-Davis
H 指数:22论文数:179被引数:2,426
S
Simon J. Leedham
H 指数:45论文数:396被引数:7,022
W
Wolf Reik
H 指数:135论文数:518被引数:7.6万
N
Nicholas A. Wright
H 指数:92论文数:907被引数:3.1万
R
Rachael Thomas
H 指数:18论文数:49被引数:1,434
E
Emma Jaeger
H 指数:22论文数:48被引数:6,296
J
James E. East
H 指数:68论文数:407被引数:1.7万
S
Shazia Irshad
H 指数:11论文数:29被引数:747
M
Manuel Rodriguez‐Justo
H 指数:57论文数:491被引数:1.1万