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H

Hayley L. Belnoue-Davis

University of Oxford
H指数:22
被引数:2,419

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Platelets sequester extracellular DNA; capturing tumor-derived and free fetal DNA

血小板隔离细胞外DNA；捕获肿瘤来源和游离胎儿DNA

Science
IF45.8
2025-08-140
PRE
Lauren Murphy; Jeanne Inchauspé; Giampiero Valenzano; Pamela Holland; Nikolaos Sousos; Hayley L. Belnoue-Davis; Rong Li; Natalie J. Jooss; Camelia Benlabiod; Eleanor Murphy; Zohar Etzioni; Emelie Shepherd; Lucy Denly; Sujata Biswas; Lin Chen; Jennifer O’Sullivan; Michael P. Rimmer; Abdullah O. Khan; Christina Simoglou Karali; Nadia Nasreddin; Ian S. Hitchcock; Milka Koupenova; Skirmantas Kriaucionis; Jim R. Hughes; Eric O’Neill; Manu Vatish; Paul Rees; Simon Leedham; Michael Desborough; Adam J. Mead; Benjamin Schuster-Böckler; Christopher D. Gregory; Bethan Psaila
Epithelial GREMLIN1 disrupts intestinal epithelial-mesenchymal crosstalk to induce a wnt-dependent ectopic stem cell niche through stromal remodelling

上皮GREMLIN1通过基质重塑破坏肠上皮-间质细胞通讯，诱导Wnt依赖性的异位干细胞微环境。

Nature Communications
IF15.7
2025-06-040
OAAI
Eoghan J. Mulholland; Hayley L. Belnoue-Davis; Gabriel N. Valbuena; Nuray Gunduz; Amelia Ligeza; Muyang Lin; Sujata Biswas; Ester Gil Vasquez; Sulochana Omwenga; Nadia Nasreddin; Michael C. Hodder; Lai Mun Wang; Aik Seng Ng; Elizabeth Jennings; Kim S. Midwood; Neesha Dedi; Shazia Irshad; Rachel A. Ridgway; Toby J. Phesse; James East; Ian PM Tomlinson; Gareth CG Davies; Owen J. Sansom; Simon J. Leedham
Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis

低覆盖度全基因组测序对溃疡性结肠炎中低级别异型增生的癌前病变进展风险具有强预测作用

GUT
IF25.8
2025-01-291
PRE
Al Bakir, Ibrahim; Curtius, Kit; Cresswell, George D.; Grant, Heather E.; Nasreddin, Nadia; Smith, Kane; Nowinski, Salpie; Guo, Qingli; Belnoue-Davis, Hayley L.; Fisher, Jennifer; Clarke, Theo; Kimberley, Christopher; Mossner, Maximilian; Dunne, Philip D.; Loughrey, Maurice B.; Speight, Ally; East, James E.; Wright, Nicholas A.; Rodriguez-Justo, Manuel; Jansen, Marnix; Moorghen, Morgan; Baker, Ann-Marie; Leedham, Simon J.; Hart, Ailsa L.; Graham, Trevor A.
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer (Vol 56, pg 458, 2024)
NATURE GENETICS
IF31.8
2024-06-031
OAAI
Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; McCooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer
NATURE GENETICS
IF31.8
2024-02-1310
OAAI
Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; Mccooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.
Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features

上皮tgf β 参与生长因子信号传导以避免细胞凋亡并以侵袭性特征驱动肠道肿瘤发生

NATURE COMMUNICATIONS
IF15.7
2022-12-074
OAAI
Flanagan, Dustin J.; Amirkhah, Raheleh; Vincent, David F.; Gunduz, Nuray; Gentaz, Pauline; Cammareri, Patrizia; McCooey, Aoife J.; McCorry, Amy M. B.; Fisher, Natalie C.; Davis, Hayley L.; Ridgway, Rachel A.; Lohuis, Jeroen; Leach, Joshua D. G.; Jackstadt, Rene; Gilroy, Kathryn; Mariella, Elisa; Nixon, Colin; Clark, William; Hedley, Ann; Markert, Elke K.; Strathdee, Douglas; Bartholin, Laurent; Redmond, Keara L.; Kerr, Emma M.; Longley, Daniel B.; Ginty, Fiona; Cho, Sanghee; Coleman, Helen G.; Loughrey, Maurice B.; Bardelli, Alberto; Maughan, Timothy S.; Campbell, Andrew D.; Lawler, Mark; Leedham, Simon J.; Barry, Simon T.; Inman, Gareth J.; van Rheenen, Jacco; Dunne, Philip D.; Sansom, Owen J.
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia (vol 29, pg 1213, 2022)
CELL STEM CELL
IF20.4
2022-11-010
OA
Vazquez, Ester Gil; Nasreddin, Nadia; Valbuena, Gabriel N.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Eggington, Holly R.; Schenck, Ryan O.; Wouters, Valerie M.; Wirapati, Pratyaksha; Gilroy, Kathryn; Lannagan, Tamsin R. M.; Flanagan, Dustin J.; Najumudeen, Arafath K.; Omwenga, Sulochana; McCorry, Amy M. B.; Easton, Alistair; Koelzer, Viktor H.; East, James E.; Morton, Dion; Trusolino, Livio; Maughan, Timothy; Campbell, Andrew D.; Loughrey, Maurice B.; Dunne, Philip D.; Tsantoulis, Petros; Huels, David J.; Tejpar, Sabine; Sansom, Owen J.; Leedham, Simon J.
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia

结肠直肠肿瘤中动态和适应性的癌症干细胞群混合

CELL STEM CELL
IF20.4
2022-08-0146
OAAI
Vasquez, Ester Gil; Nasreddin, Nadia; Valbuena, Gabriel N.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Eggington, Holly R.; Schenck, Ryan O.; Wouters, Valerie M.; Wirapati, Pratyaksha; Gilroy, Kathryn; Lannagan, Tamsin R. M.; Flanagan, Dustin J.; Najumudeen, Arafath K.; Omwenga, Sulochana; McCorry, Amy M. B.; Easton, Alistair; Koelzer, Viktor H.; East, James E.; Morton, Dion; Trusolino, Livio; Maughan, Timothy; Campbell, Andrew D.; Loughrey, Maurice B.; Dunne, Philip D.; Tsantoulis, Petros; Huels, David J.; Tejpar, Sabine; Sansom, Owen J.; Leedham, Simon J.
The polymorphic variant rs1800734 influences methylation acquisition and allele-specific TFAP4 binding in the MLH1 promoter leading to differential mRNA expression
SCIENTIFIC REPORTS
IF3.9
2019-09-178
OAAI
Thomas, Rachael; Trapani, Davide; Goodyer-Sait, Lily; Tomkova, Marketa; Fernandez-Rozadilla, Ceres; Sahnane, Nora; Woolley, Connor; Davis, Hayley; Chegwidden, Laura; Kriaucionis, Skirmantas; Maughan, Timothy; Leedham, Simon; Palles, Claire; Furlan, Daniela; Tomlinson, Ian; Lewis, Annabelle
The evolutionary landscape of colorectal tumorigenesis

结直肠肿瘤发生的进化景观

NATURE ECOLOGY & EVOLUTION
IF14.5
2018-08-3189
OAAI
Cross, William; Kovac, Michal; Mustonen, Ville; Temko, Daniel; Davis, Hayley; Baker, Ann-Marie; Biswas, Sujata; Arnold, Roland; Chegwidden, Laura; Gatenbee, Chandler; Anderson, Alexander R.; Koelzer, Viktor H.; Martinez, Pierre; Jiang, Xiaowei; Domingo, Enric; Woodcock, Dan J.; Feng, Yun; Kovacova, Monika; Maughan, Tim; Jansen, Marnix; Rodriguez-Justo, Manuel; Ashraf, Shazad; Guy, Richard; Cunningham, Christopher; East, James E.; Wedge, David C.; Wang, Lai Mun; Palles, Claire; Heinimann, Karl; Sottoriva, Andrea; Leedham, Simon J.; Graham, Trevor A.; Tomlinson, Ian P. M.
The evolutionary history of human colitis-associated colorectal cancer
CANCER RESEARCH
IF16.6
2018-07-010
PRE
Baker, Ann-Marie; Cross, William; Curtius, Kathleen; Choi, Chang-ho Ryan; Al-Bakir, Ibrahim; Temko, Daniel; Martinez, Pierre; Williams, Marc; Davis, Hayley; Biswas, Sujata; Wright, Nicholas A.; Moorghen, Morgan; Hayes, Stephen J.; Rodriguez-Justo, Manuel; Silver, Andrew; Wang, Lai Mun; Jansen, Marnix; Hart, Ailsa L.; Leedham, Simon J.; Graham, Trevor A.
Bone morphogenetic protein and Notch signalling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer

预后不良，间充质亚型结直肠癌中的骨形态发生蛋白和Notch信号串扰

JOURNAL OF PATHOLOGY
IF5.2
2017-05-0343
OAAI
Irshad, Shazia; Bansal, Mukesh; Guarnieri, Paolo; Davis, Hayley; Zen, Ayman Al Haj; Baran, Brygida; Pinna, Claudia Maria Assunta; Rahman, Haseeb; Biswas, Sujata; Bardella, Chiara; Jeffery, Rosemary; Wang, Lai Mun; East, James Edward; Tomlinson, Ian; Lewis, Annabelle; Leedham, Simon John
MULTI-REGION EXOME SEQUENCING REVEALS THE CLONAL EVOLUTION OF COLITIS-ASSOCIATED COLORECTAL CANCER
GASTROENTEROLOGY
IF25.1
2017-04-010
PREAI
Baker, Ann-Marie; Davis, Chang Ho R. Choi Hayley; Al-Bakir, Ibrahim; Martinez, Pierre; Temko, Daniel; Cross, William; Williams, Marc; Biswas, Sujata; McDonald, Stuart A.; Wright, Nicholas A.; Tomlinson, Ian; Moorghen, Morgan; Hayes, Stephen; Rodriguez-Justo, Manuel; Silver, Andrew; Wang, Lai Mun; Jansen, Marnix; Hart, Ailsa; Leedham, Simon; Graham, Trevor A.

研究方向

暂未获取到该数据
S
Simon J. Leedham
H 指数:45论文数:396被引数:7,011
I
Ian Tomlinson
H 指数:129论文数:1,284被引数:6.1万
A
Annabelle Lewis
H 指数:24论文数:64被引数:3,229
J
James E. East
H 指数:68论文数:407被引数:1.7万
O
Owen J. Sansom
H 指数:113论文数:1,190被引数:5.1万
S
Sujata Biswas
H 指数:17论文数:57被引数:1,167
M
Maurice B. Loughrey
H 指数:41论文数:288被引数:1.4万
M
Manuel Rodriguez‐Justo
H 指数:57论文数:491被引数:1.1万
V
Viktor H. Koelzer
H 指数:49论文数:379被引数:7,975
P
Philip D. Dunne
H 指数:35论文数:521被引数:1.3万