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M

Matthieu Desroses

Université de Lille
H指数:22
被引数:1,895

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Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM
NATURE COMMUNICATIONS
IF15.7
2024-12-060
OAAI
Valerie, Nicholas C. K.; Sanjiv, Kumar; Mortusewicz, Oliver; Zhang, Si Min; Alam, Seher; Pires, Maria J.; Stigsdotter, Hannah; Rasti, Azita; Langelier, Marie-France; Rehling, Daniel; Throup, Adam; Purewal-Sidhu, Oryn; Desroses, Matthieu; Onireti, Jacob; Wakchaure, Prasad; Almloef, Ingrid; Bostrom, Johan; Bevc, Luka; Benzi, Giorgia; Stenmark, Pal; Pascal, John M.; Helleday, Thomas; Page, Brent D. G.; Altun, Mikael
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
NATURE CANCER
IF28.5
2022-02-2837
OAAI
Bonagas, Nadilly; Gustafsson, Nina M. S.; Henriksson, Martin; Marttila, Petra; Gustafsson, Robert; Wiita, Elisee; Borhade, Sanjay; Green, Alanna C.; Vallin, Karl S. A.; Sarno, Antonio; Svensson, Richard; Gokturk, Camilla; Pham, Therese; Jemth, Ann-Sofie; Loseva, Olga; Cookson, Victoria; Kiweler, Nicole; Sandberg, Lars; Rasti, Azita; Unterlass, Judith E.; Haraldsson, Martin; Andersson, Yasmin; Scaletti, Emma R.; Bengtsson, Christoffer; Paulin, Cynthia B. J.; Sanjiv, Kumar; Abdurakhmanov, Eldar; Pudelko, Linda; Kunz, Ben; Desroses, Matthieu; Iliev, Petar; Farnegardh, Katarina; Kramer, Andreas; Garg, Neeraj; Michel, Maurice; Haggblad, Sara; Jarvius, Malin; Kalderen, Christina; Jensen, Amanda Bogedahl; Almlof, Ingrid; Karsten, Stella; Zhang, Si Min; Haggblad, Maria; Eriksson, Anders; Liu, Jianping; Glinghammar, Bjorn; Nekhotiaeva, Natalia; Klingegard, Fredrik; Koolmeister, Tobias; Martens, Ulf; Llona-Minguez, Sabin; Moulson, Ruth; Nordstrom, Helena; Parrow, Vendela; Dahllund, Leif; Sjoberg, Birger; Vargas, Irene L.; Vo, Duy Duc; Wannberg, Johan; Knapp, Stefan; Krokan, Hans E.; Arvidsson, Per, I; Scobie, Martin; Meiser, Johannes; Stenmark, Pal; Berglund, Ulrika Warpman; Homan, Evert J.; Helleday, Thomas
Development of a chemical probe against NUDT15
NATURE CHEMICAL BIOLOGY
IF13.7
2020-07-2012
OAAI
Zhang, Si Min; Desroses, Matthieu; Hagenkort, Anna; Valerie, Nicholas C. K.; Rehling, Daniel; Carter, Megan; Wallner, Olov; Koolmeister, Tobias; Throup, Adam; Jemth, Ann-Sofie; Almlof, Ingrid; Loseva, Olga; Lundback, Thomas; Axelsson, Hanna; Regmi, Shruti; Sarno, Antonio; Kraemer, Andreas; Pudelko, Linda; Brautigam, Lars; Rasti, Azita; Gottmann, Mona; Wiita, Elisee; Kutzner, Juliane; Schaller, Torsten; Kalderen, Christina; Cazares-Korner, Armando; Page, Brent D. G.; Krimpenfort, Rosa; Eshtad, Saeed; Altun, Mikael; Rudd, Sean G.; Knapp, Stefan; Scobie, Martin; Homan, Evert J.; Berglund, Ulrika Warpman; Stenmark, Pal; Helleday, Thomas
Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors (vol 60, pg 4279, 2017)
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2017-09-011
OAAI
Llona-Minguez, Sabin; Hoglund, Andreas; Ghassemian, Artin; Desroses, Matthieu; Calderon-Montano, Jose Manuel; Moron, Estefania Burgos; Valerie, Nicholas C. K.; Wiita, Elisee; Almlof, Ingrid; Koolmeister, Tobias; Mateus, Andre; Cazares-Korner, Cindy; Sanjiv, Kumar; Homan, Evert; Loseva, Olga; Baranczewski, Pawel; Darabi, Masoud; Mehdizadeh, Amir; Fayezi, Shabnam; Jemth, Ann-Sofie; Berglund, Ulrika Warpman; Sigmundsson, Kristmundur; Lundback, Thomas; Jensen, Annika Jenmalm; Artursson, Per; Scobie, Martin; Helleday, Thomas
Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2017-05-1621
PREAI
Llona-Minguez, Sabin; Hoglund, Andreas; Ghassemian, Artin; Desroses, Matthieu; Calderon-Montano, Jose Manuel; Moron, Estefania Burgos; Valerie, Nicholas C. K.; Wiita, Elisee; Almlof, Ingrid; Koolmeister, Tobias; Mateus, Andre; Cazares-Korner, Cindy; Sanjiv, Kumar; Homan, Evert; Loseva, Olga; Baranczewski, Pawel; Darabi, Masoud; Mehdizadeh, Amir; Fayezi, Shabnam; Jemth, Ann-Sofie; Berglund, Ulrika Warpman; Sigmundsson, Kristmundur; Lundback, Thomas; Jensen, Annika Jenmalm; Artursson, Per; Scobie, Martin; Helleday, Thomas
Discovery of Novel N-Phenylphenoxyacetamide Derivatives as EthR Inhibitors and Ethionamide Boosters by Combining High-Throughput Screening and Synthesis
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2012-07-1744
PREAI
Flipo, Marion; Willand, Nicolas; Lecat-Guillet, Nathalie; Hounsou, Candide; Desroses, Matthieu; Leroux, Florence; Lens, Zoe; Villeret, Vincent; Wohlkonig, Alexandre; Wintjens, Rene; Christophe, Thierry; Jeon, Hee Kyoung; Locht, Camille; Brodin, Priscille; Baulard, Alain R.; Deprez, Benoit
Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2011-12-0678
PREAI
Flipo, Marion; Desroses, Matthieu; Lecat-Guillet, Nathalie; Villemagne, Baptiste; Blondiaux, Nicolas; Leroux, Florence; Piveteau, Catherine; Mathys, Vanessa; Flament, Marie-Pierre; Siepmann, Juergen; Villeret, Vincent; Wohlkonig, Alexandre; Wintjens, Rene; Soror, Sameh H.; Christophe, Thierry; Jeon, Hee Kyoung; Locht, Camille; Brodin, Priscille; Deprez, Benoit; Baulard, Alain R.; Willand, Nicolas
Ethionamide Boosters: Synthesis, Biological Activity, and Structure-Activity Relationships of a Series of 1,2,4-Oxadiazole EthR Inhibitors
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2011-04-0185
PREAI
Flipo, Marion; Desroses, Matthieu; Lecat-Guillet, Nathalie; Dirie, Bertrand; Carette, Xavier; Leroux, Florence; Piveteau, Catherine; Demirkaya, Fatma; Lens, Zoe; Rucktooa, Prakash; Villeret, Vincent; Christophe, Thierry; Jeon, Hee Kyoung; Locht, Camille; Brodin, Priscille; Deprez, Benoit; Baulard, Alain R.; Willand, Nicolas

研究方向

暂未获取到该数据
T
Thomas Helleday
H 指数:84论文数:690被引数:3.5万
A
Ann‐Sofie Jemth
H 指数:28论文数:111被引数:4,130
P
Pål Stenmark
H 指数:41论文数:289被引数:6,531
U
Ulrika Warpman Berglund
H 指数:32论文数:151被引数:3,797
B
Brent D. G. Page
H 指数:26论文数:113被引数:2,582
M
Martin Scobie
H 指数:25论文数:125被引数:2,570
E
Evert Homan
H 指数:24论文数:100被引数:2,324
N
Nicholas C.K. Valerie
H 指数:16论文数:90被引数:1,604
I
Ingrid Almlöf
H 指数:19论文数:87被引数:1,499
C
Camille Locht
H 指数:82论文数:483被引数:2.3万