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Different features of acute myeloid leukemia stem cell quantification in intensively treated patients 高强度治疗患者中急性髓系白血病干细胞定量测定的不同特征。Haematologica Ngai, Lok Lam; Reuvekamp, Tom; Hanekamp, Diana; Janssen, Fleur; Oudshoorn-van Marsbergen, Laura; Carbaat-Ham, Jannemieke; Hofland, Maaike A. M.; Fayed, Mona M. H. E.; Kelder, Angele; Scholten, Willemijn J.; Snel, Alexander N.; Bachas, Costa; Tettero, Jesse M.; Breems, Dimitri A.; Fischer, Thomas; Gjertsen, Bjorn T.; Griskevicius, Laimonas; Juliusson, Gunnar; van de Loosdrecht, Arjan A.; Maertens, Johan A.; Manz, Markus G.; Pabst, Thomas; Passweg, Jakob R.; Porkka, Kimmo; Valk, Peter J. M.; Gradowska, Patrycja; Lowenberg, Bob; Ossenkoppele, Gert J.; de Leeuw, David C.; Cloos, Jacqueline 分享 收藏
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Integrating Computational Cytomorphological Analysis of Bone Marrow Smears and Clinical Data for Predicting Response to Venetoclax and Hypomethylating Agents in AML 整合骨髓涂片的计算细胞形态学分析与临床数据，以预测AML对Venetoclax和表观遗传学药物的反应 Sundquist, Henri; Tatun, Mikael; Purhonen, Mikko; Toivanen, Laura; Rimpilainen, Johanna; Rounioja, Samuli; Siitonen, Timo; Pyorala, Marja; Mantymaa, Pentti; Kytola, Sari; Porkka, Kimmo; Siitonen, Sanna; Kuusanmaki, Heikki; Kontro, Mika; Bruck, Oscar E. 分享 收藏
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Computational Cytomorphological Analyses Identifies Bone Marrow Erythroblast Proportion As a Biomarker of Treatment-Free Remission in CML 计算细胞形态学分析将骨髓红细胞比例鉴定为CML治疗无复发的生物标志物 Purhonen, Mikko; Tatun, Mikael; Hung, Kevin; Tafjord, Oda; Adnan-Awad, Shady; Koskenvesa, Perttu; Siitonen, Sanna; Porkka, Kimmo; Mustjoki, Satu; Danielsson, Signe; Hjorth-Hansen, Henrik; Olsson-Stromberg, Ulla; Kumagai, Takashi; Kimura, Shinya; Ross, David M.; Bruck, Oscar E. 分享 收藏
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Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones 单细胞转录组鉴定针对癌症克隆的选择性共抑制的患者定制疗法 Ianevski, Aleksandr; Nader, Kristen; Driva, Kyriaki; Senkowski, Wojciech; Bulanova, Daria; Moyano-Galceran, Lidia; Ruokoranta, Tanja; Kuusanmaki, Heikki; Ikonen, Nemo; Sergeev, Philipp; Vaha-Koskela, Markus; Giri, Anil K.; Vaharautio, Anna; Kontro, Mika; Porkka, Kimmo; Pitkanen, Esa; Heckman, Caroline A.; Wennerberg, Krister; Aittokallio, Tero 分享 收藏
Acquired Multidrug Resistance in AML Is Caused by Low Apoptotic Priming in Relapsed Myeloblasts Olesinski, Elyse A.; Bhatia, Karanpreet Singh; Wang, Chuqi; Pioso, Marissa S.; Lin, Xiao Xian; Mamdouh, Ahmed M.; Ng, Shu Xuan; Sandhu, Vedant; Jasdanwala, Shaista Shabbir; Yilma, Binyam; Bohl, Stephan; Ryan, Jeremy A.; Malani, Disha; Luskin, Marlise R.; Kallioniemi, Olli; Porkka, Kimmo; Adamia, Sophia; Chng, Wee Joo; Osato, Motomi; Weinstock, David M.; Garcia, Jacqueline S.; Letai, Anthony; Bhatt, Shruti 分享 收藏
Integrated drug profiling and CRISPR screening identify BCR::ABL1-independent vulnerabilities in chronic myeloid leukemia 综合药物分析和CRISPR筛选确定BCR:: 慢性粒细胞白血病的ABL1-independent脆弱性 Awad, Shady Adnan; Dufva, Olli; Klievink, Jay; Karjalainen, Ella; Ianevski, Aleksandr; Pietarinen, Paavo; Kim, Daehong; Potdar, Swapnil; Wolf, Maija; Lotfi, Kourosh; Aittokallio, Tero; Wennerberg, Krister; Porkka, Kimmo; Mustjoki, Satu 分享 收藏
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Long-term follow-up of VIALE-A: Venetoclax and azacitidine in chemotherapy-ineligible untreated acute myeloid leukemia Pratz, Keith W.; Jonas, Brian A.; Pullarkat, Vinod; Thirman, Michael J.; Garcia, Jacqueline S.; Doehner, Hartmut; Recher, Christian; Fiedler, Walter; Yamamoto, Kazuhito; Wang, Jianxiang; Yoon, Sung-Soo; Wolach, Ofir; Yeh, Su-Peng; Leber, Brian; Esteve, Jordi; Mayer, Jiri; Porkka, Kimmo; Illes, Arpad; Lemoli, Roberto M.; Turgut, Mehmet; Ku, Grace; Miller, Catherine; Zhou, Ying; Zhang, Meng; Chyla, Brenda; Potluri, Jalaja; Dinardo, Courtney D. 分享 收藏
Phase Ib study of sabatolimab (MBG453), a novel immunotherapy targeting TIM-3 antibody, in combination with decitabine or azacitidine in high- or very high-risk myelodysplastic syndromes 针对TIM-3抗体的新型免疫疗法sabatolimab (MBG453) 与地西他滨或阿扎胞苷联合治疗高危或极高危骨髓增生异常综合征的Ib期研究 Brunner, Andrew M.; Esteve, Jordi; Porkka, Kimmo; Knapper, Steve; Traer, Elie; Scholl, Sebastian; Garcia-Manero, Guillermo; Vey, Norbert; Wermke, Martin; Janssen, Jeroen J. W. M.; Narayan, Rupa; Fleming, Shaun; Loo, Sun; Tovar, Natalia; Kontro, Mika; Ottmann, Oliver G.; Naidu, Purushotham; Sun, Haiying; Han, May; White, Roisin; Zhang, Na; Mohammed, Anisa; Sabatos-Peyton, Catherine A.; Steensma, David P.; Rinne, Mikael L.; Borate, Uma M.; Wei, Andrew H. 分享 收藏
Real-world evidence of multiple myeloma treated from 2013 to 2019 in the Hospital District of Helsinki and Uusimaa, Finland Vikkula, Johanna; Uusi-Rauva, Kristiina; Ranki, Tuuli; Toppila, Iiro; Aalto-Setala, Maria; Pousar, Katariina; Vassilev, Lotta; Porkka, Kimmo; Silvennoinen, Raija; Bruck, Oscar 分享 收藏
Identification of DHX40 as a candidate susceptibility gene for colorectal and hematological neoplasia 鉴定DHX40作为结直肠和血液肿瘤的候选易感基因 Olkinuora, Alisa; Nieminen, Taina T.; Douglas, Suvi; Kauppinen, Anni; Kontro, Mika; Vaananen, Juho; Kankainen, Matti; Ristimaki, Ari; Makinen, Markus; Lahermo, Paivi; Heckman, Caroline; Saarela, Janna; Salonen, Milla; Lepisto, Anna; Jarvinen, Heikki; Mecklin, Jukka-Pekka; Kilpivaara, Outi; Wartiovaara-Kautto, Ulla; Porkka, Kimmo; Peltomaki, Paeivi 分享 收藏
A first-in-human phase 1 study of LY3410738, a covalent inhibitor of mutant IDH, in advanced myeloid malignancies DiNardo, Courtney D.; Montesinos, Pau; Benajiba, Lina; Triguero, Ana; Recher, Christian; Schuh, Andre C.; Heiblig, Mael; Bajel, Ashish; Pigneux, Arnaud; Alonso-Domiguez, Juan M.; Fathi, Amir T.; Grove, Carolyn; Hou, Hsin-An; Heuser, Michael; Assouline, Sarit; Fleming, Shaun; Shin, Dong-Yeop; Sweet, Kendra; Odenike, Olatoyosi; Altman, Jessica; Ooi, Melissa Gaik Ming; Lao Zhentang; Vey, Nobert; Zeidner, Joshua; Salhotra, Amandeep; Wang, Eunice; Schiller, Gary; Porkka, Kimmo; Zuckerman, Tsila; Havelange, Violaine; Jonas, Brian A.; Narayanan, Sujaatha; Jang, Jun Ho; Lee, Je-Hwan; Szpurka, Anna M.; Heirich, Dana; Chen, Hsiao Rong; Hanft, Violet; Zhao, Junjie; Gueorguieva, Ivelina; Zhang, Yin; Stein, Eytan M. 分享 收藏
Measurable residual disease-guided therapy in intermediate-risk acute myeloid leukemia patients is a valuable strategy in reducing allogeneic transplantation without negatively affecting survival Tettero, Jesse M.; Ngai, Lok Lam; Bachas, Costa; Breems, Dimitri A.; Fischer, Thomas; Gjertsen, Bjorn T.; Gradowska, Patrycja; Griskevicius, Laimonas; Janssen, Jeroen J. W. M.; Juliusson, Gunnar; Maertens, Johan; Manz, Markus G.; Pabst, Thomas; Passweg, Jakob; Porkka, Kimmo; Valk, Peter J. M.; Loewenberg, Bob; Ossenkoppele, Gert J.; Cloos, Jacqueline 分享 收藏
Early response evaluation by single cell signaling profiling in acute myeloid leukemia (vol 14, 115, 2023) Tislevoll, Benedicte Sjo; Hellesoy, Monica; Fagerholt, Oda Helen Eck; Gullaksen, Stein-Erik; Srivastava, Aashish; Birkeland, Even; Kleftogiannis, Dimitrios; Ayuda-Duran, Pilar; Piechaczyk, Laure; Tadele, Dagim Shiferaw; Skavland, Jorn; Baliakas, Panagotis; Hovland, Randi; Andresen, Vibeke; Seternes, Ole Morten; Tvedt, Tor Henrik Anderson; Aghaeepour, Nima; Gavasso, Sonia; Porkka, Kimmo; Jonassen, Inge; Floisand, Yngvar; Enserink, Jorrit; Blaser, Nello; Gjertsen, Bjorn Tore 分享 收藏
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