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C

Chantal Ferguson

massachusetts general hospital
H指数:20
被引数:1,389

个人简介

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荣誉奖项

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Systematic analysis of siRNA and mRNA features impacting fully chemically modified siRNA efficacy

siRNA和mRNA特征对全化学修饰siRNA功效影响的系统分析

NUCLEIC ACIDS RESEARCH
IF13.1
2025-07-084
OAAI
Davis, Sarah M.; Hildebrand, Samuel; MacMillan, Hannah J.; Monopoli, Kathryn R.; Buchwald, Julianna; Sousa, Jacquelyn; Cooper, David; Ly, Socheata; Echeverria, Dimas; McHugh, Nicholas; Ferguson, Chantal; Coles, Andrew; Hariharan, Vignesh N.; O'Reilly, Daniel; Tang, Qi; Furgal, Raymond; Yamada, Ken; Alterman, Julia F.; Gilbert, James W.; Knox, Emily; Pineda, Yamilett; Weston, Caitlyn N.; Baer, Christina E.; Pai, Athma A.; Khvorova, Anastasia
RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice

RNAi介导的SOD1沉默显著延长了ALS小鼠的生存期和功能结局。

Molecular Therapy
IF12
2025-05-090
OAAI
Alexandra Weiss; James W. Gilbert; Iris Valeria Rivera Flores; Jillian Belgrad; Chantal Ferguson; Elif O. Dogan; Nicholas Wightman; Kit Mocarski; Dimas Echeverria; Ashley L. Harkins; Ashley Summers; Brianna Bramato; Nicholas McHugh; Raymond Furgal; Nozomi Yamada; David Cooper; Kathryn Monopoli; Bruno M.D.C. Godinho; Matthew R. Hassler; Ken Yamada; Paul Greer; Nils Henninger; Robert H. Brown; Anastasia Khvorova
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones
NATURE BIOTECHNOLOGY
IF41.7
2024-08-011
PRE
Yamada, Ken; Hariharan, Vignesh N.; Caiazzi, Jillian; Miller, Rachael; Ferguson, Chantal M.; Sapp, Ellen; Fakih, Hassan H.; Tang, Qi; Yamada, Nozomi; Furgal, Raymond C.; Paquette, Joseph D.; Biscans, Annabelle; Bramato, Brianna M.; Mchugh, Nicholas; Summers, Ashley; Lochmann, Clemens; Godinho, Bruno M. D. C.; Hildebrand, Samuel; Jackson, Samuel O.; Echeverria, Dimas; Hassler, Matthew R.; Alterman, Julia F.; Difiglia, Marian; Aronin, Neil; Khvorova, Anastasia
Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease

用二价sirna沉默Apoe可改善淀粉样蛋白负荷并激活阿尔茨海默氏病的免疫反应途径

ALZHEIMERS & DEMENTIA
IF11.1
2024-02-209
OAAI
Ferguson, Chantal M.; Hildebrand, Samuel; Godinho, Bruno M. D. C.; Buchwald, Julianna; Echeverria, Dimas; Coles, Andrew; Grigorenko, Anastasia; Vangjeli, Lorenc; Sousa, Jacquelyn; McHugh, Nicholas; Hassler, Matthew; Santarelli, Francesco; Heneka, Michael T.; Rogaev, Evgeny; Khvorova, Anastasia
A combinatorial approach for achieving CNS-selective RNAi

实现CNS选择性RNAi的组合方法

NUCLEIC ACIDS RESEARCH
IF13.1
2024-02-132
OAAI
Ferguson, Chantal M.; Godinho, Bruno M. D. C.; Echeverria, Dimas; Hassler, Matthew; Vangjeli, Lorenc; Sousa, Jacquelyn; Mchugh, Nicholas; Alterman, Julia; Hariharan, Vignesh; Krishnamurthy, Pranathi Meda; Watts, Jonathan; Rogaev, Eveny; Khvorova, Anastasia
Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease (may, 10.1016/j.ymthe.2023.05.006, 2023)
MOLECULAR THERAPY
IF12
2023-11-010
OAAI
O'Reilly, Daniel; Belgrad, Jillian; Ferguson, Chantal; Summers, Ashley; Sapp, Ellen; McHugh, Cassandra; Mathews, Ella; Boudi, Adel; Buchwald, Julianna; Ly, Socheata; Moreno, Dimas; Furgal, Raymond; Luu, Eric; Kennedy, Zachary; Hariharan, Vignesh; Monopoli, Kathryn; Yang, X. William; Carroll, Jeffery; DiFiglia, Marian; Aronin, Neil; Khvorova, Anastasia
Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease
MOLECULAR THERAPY
IF12
2023-06-0123
OAAI
O 'Reilly, Daniel; Belgrad, Jillian; Ferguson, Chantal; Summers, Ashley; Sapp, Ellen; McHugh, Cassandra; Mathews, Ella; Boudi, Adel; Buchwald, Julianna; Ly, Socheata; Moreno, Dimas; Furgal, Raymond; Luu, Eric; Kennedy, Zachary; Hariharan, Vignesh; Monopoli, Kathryn; Yang, William; Carroll, Jeffery; DiFiglia, Marian; Aronin, Neil; Khvorova, Anastasia
Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection

二价sirna在肺中是生物可利用的并有效阻断SARS-CoV-2感染

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-03-0923
OAAI
Hariharan, Vignesh N.; Shin, Minwook; Chang, Ching-Wen; O'Reilly, Daniel; Biscans, Annabelle; Yamada, Ken; Guo, Zhiru; Somasundaran, Mohan; Tang, Qi; Monopoli, Kathryn; Krishnamurthy, Pranathi Meda; Devi, Gitali; McHugh, Nicholas; Cooper, David A.; Echeverria, Dimas; Cruz, John; Chan, Io Long; Liu, Ping; Lim, Sun-Young; McConnell, Jill; Singh, Satya Prakash; Hildebrand, Samuel; Sousa, Jacquelyn; Davis, Sarah M.; Kennedy, Zachary; Ferguson, Chantal; Godinho, Bruno M. D. C.; Thillier, Yann; Caiazzi, Jillian; Ly, Socheata; Muhuri, Manish; Kelly, Karen; Humphries, Fiachra; Cousineau, Alyssa; Parsi, Krishna Mohan; Li, Qi; Wang, Yang; Maehr, Rene; Gao, Guangping; Korkin, Dmitry; McDougall, William M.; Finberg, Robert W.; Fitzgerald, Katherine A.; Wang, Jennifer P.; Watts, Jonathan K.; Khvorova, Anastasia
A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system

二价siRNA化学支架，用于有效和持续地调节整个中枢神经系统的基因表达

NATURE BIOTECHNOLOGY
IF41.7
2019-08-02148
OAAI
Alterman, Julia F.; Godinho, Bruno M. D. C.; Hassler, Matthew R.; Ferguson, Chantal M.; Echeverria, Dimas; Sapp, Ellen; Haraszti, Reka A.; Coles, Andrew H.; Conroy, Faith; Miller, Rachael; Roux, Loic; Yan, Paul; Knox, Emily G.; Turanov, Anton A.; King, Robert M.; Gernoux, Gwladys; Mueller, Christian; Gray-Edwards, Heather L.; Moser, Richard P.; Bishop, Nina C.; Jaber, Samer M.; Gounis, Matthew J.; Sena-Esteves, Miguel; Pai, Athma A.; DiFiglia, Marian; Aronin, Neil; Khvorova, Anastasia

研究方向

暂未获取到该数据
A
Anastasia Khvorova
H 指数:58论文数:215被引数:3.1万
D
Dimas Echeverria
H 指数:31论文数:118被引数:3,548
B
Bruno M.D.C. Godinho
H 指数:25论文数:50被引数:2,602
M
Matthew Hassler
H 指数:23论文数:56被引数:2,724
C
Cynthia L. Miller
H 指数:31论文数:120被引数:3,497
N
Nora Horick
H 指数:45论文数:353被引数:8,817
M
Meyha N. Swaroop
H 指数:10论文数:43被引数:933
M
Melissa N. Skolny
H 指数:25论文数:87被引数:2,649
A
Alphonse G. Taghian
H 指数:71论文数:432被引数:1.6万
A
Andrew H. Coles
H 指数:30论文数:59被引数:4,067