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S

Simon A. Smith

AstraZeneca
H指数:30
被引数:3,074

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A Phase Ib/II study of ceralasertib, a selective inhibitor of ATR, in patients with relapsed or refractory MDS and CMML

Ib/II期研究：ceralasertib（一种ATR选择性抑制剂）在复发或难治性MDS和CMML患者中的研究

Blood Advances
IF7.1
2026-07-020
OA
Andrew M. Brunner; Yiwen Liu; Jacqueline S. Garcia; Lourdes Mendez; Catherine Gutierrez Moore; Sridhar Nonavinkere Srivatsan; Jin Shao; Brandon J. Aubrey; Philip Amrein; Rupa Narayan; Rahul Vedula; Eliana Friedman; Donna Neuberg; Marcio Andrade-Campos; Simon A. Smith; Richard Stone; Amir T. Fathi; Matthew J. Walter; Timothy A. Graubert; Meagan A. Jacoby
Tumor control and immune activation through palliative irradiation and ATR inhibition, PATRIOT Part C: a phase Ib trial

通过姑息性放疗和ATR抑制实现肿瘤控制和免疫激活，PATRIOT Part C：一项 Ib 期临床试验

Nature Communications
IF15.7
2025-08-010
OAAI
Magnus T. Dillon; Emmanuel C. Patin; Kabir Mohammed; Jeane Guevara; Simon A. Smith; Emma Dean; Heba Soliman; Pablo Nenclares; Motoko Ryugenji; Davina Northcote; Neel Shah; Lorna Grove; Christopher J. Lord; Stephen Pettit; Matt Tall; Karen E. Swales; Udai Banerji; Alan A. Melcher; Mark Saunders; Martin D. Forster; Kevin J. Harrington
Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent adjuvant immunotherapy
NATURE COMMUNICATIONS
IF15.7
2024-08-130
OAAI
Patin, Emmanuel C.; Nenclares, Pablo; Hak, Charleen Chan Wah; Dillon, Magnus T.; Patrikeev, Anton; Mclaughlin, Martin; Grove, Lorna; Foo, Shane; Soliman, Heba; Barata, Joao P.; Marsden, Joanna; Baldock, Holly; Gkantalis, Jim; Roulstone, Victoria; Kyula, Joan; Burley, Amy; Hubbard, Lisa; Pedersen, Malin; Smith, Simon A.; Clancy-Thompson, Eleanor; Melcher, Alan A.; Ono, Masahiro; Rullan, Antonio; Harrington, Kevin J.
Durable responses to ATR inhibition with ceralasertib in tumors with genomic defects and high inflammation
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-01-168
OAAI
Dillon, Magnus T.; Guevara, Jeane; Mohammed, Kabir; Patin, Emmanuel C.; Smith, Simon A.; Dean, Emma; Jones, Gemma N.; Willis, Sophie E.; Petrone, Marcella; Silva, Carlos; Thway, Khin; Bunce, Catey; Roxanis, Ioannis; Nenclares, Pablo; Wilkins, Anna; Mclaughlin, Martin; Jayme-Laiche, Adoracion; Benafif, Sarah; Nintos, Georgios; Kwatra, Vineet; Grove, Lorna; Mansfield, David; Proszek, Paula; Martin, Philip; Moore, Luiza; Swales, Karen E.; Banerji, Udai; Saunders, Mark P.; Spicer, James; Forster, Martin D.; Harrington, Kevin J.
Combination ATR (ceralasertib) and PARP (olaparib) Inhibitor (CAPRI) Trial in Acquired PARP Inhibitor- Resistant Homologous Recombination-Deficient Ovarian Cancer
CLINICAL CANCER RESEARCH
IF10.2
2023-04-2520
OA
Wethington, Stephanie L.; Shah, Payal D.; Martin, Lainie; Tanyi, Janos L.; Latif, Nawar; Morgan, Mark; Torigian, Drew A.; Rodriguez, Diego; Smith, Simon A.; Dean, Emma; Domchek, Susan M.; Drapkin, Ronny; Shih, Ie-Ming; Brown, Eric J.; Hwang, Wei -Ting; Armstrong, Deborah K.; Gaillard, Stephanie; Giuntoli, Robert; Simpkins, Fiona
Development of AZD2811, an aurora kinase B inhibitor, incorporated into an Accurin™ nanoparticle for use in haematological and solid cancers
CANCER RESEARCH
IF16.6
2017-07-010
PRE
Ashton, Susan; Floch, Nicholas; Taylor, Paula; Howes, Colin; Ferguson, Doug; Ling, Matthew; Hattersley, Maureen; Wen, Shenghua; Maratea, Kim; Hughes, Adina; Redmond, Sean; Brugger, Wolfram; Smith, Simon; MacDonald, Alexander; Parry, Keith; Burris, Howard; Song, Young-Ho; Nolan, Jim; Pease, Elizabeth; Barry, Simon T.
AZD3514, an oral selective androgen receptor down-regulator in patients with castration-resistant prostate cancer - results of two parallel first-in-human phase I studies
INVESTIGATIONAL NEW DRUGS
IF2.7
2015-04-3048
PREAI
Omlin, A.; Jones, R. J.; van der Noll, R.; Satoh, T.; Niwakawa, M.; Smith, S. A.; Graham, J.; Ong, M.; Finkelman, R. D.; Schellens, J. H. M.; Zivi, A.; Crespo, M.; Riisnaes, R.; Nava-Rodrigues, D.; Malone, M. D.; Dive, C.; Sloane, R.; Moore, D.; Alumkal, J. J.; Dymond, A.; Dickinson, P. A.; Ranson, M.; Clack, G.; de Bono, J.; Elliott, T.

研究方向

暂未获取到该数据
D
Dean, Emma
H 指数:0论文数:2被引数:90
K
Kevin J. Harrington
H 指数:115论文数:1,484被引数:7.2万
M
Magnus T. Dillon
H 指数:19论文数:70被引数:2,033
L
Lorna Grove
H 指数:13论文数:46被引数:601
M
Martin Förster
H 指数:60论文数:438被引数:2.1万
E
Emmanuel C. Patin
H 指数:19论文数:79被引数:2,194
P
Peter G. Mortimer
H 指数:20论文数:93被引数:5,218
P
Pablo Nenclares
H 指数:12论文数:64被引数:702
K
Kabir Mohammed
H 指数:19论文数:106被引数:2,150
S
Simon J. Hollingsworth
H 指数:20论文数:117被引数:3,979