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C

Charlotte Kloft

freie universitat berlin

39H指数
312论文数
5.7K被引数
收录论文 133
发表时间
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In vitro feasibility studies for clinical microdialysis with lipophilic compounds: A case study with the antifungal posaconazole体外临床微透析的可行性研究：以抗真菌药物泊沙康唑为例
errJournal of Pharmaceutical Sciences
IF3.8
err2026-08-19
err0
errOAAI
errAmrei-Pauline Konrad; Linda Brita Sofia Aulin; Gerd Mikus; Charlotte Kloft
err分享
err收藏
Optimizing Clinical Study Designs for CAR-T Cell Therapy: Development of an Efficient Sampling Strategy Through Optimal Experimental Design优化CAR-T细胞治疗的临床研究设计：通过最优实验设计开发高效的采样策略
errcpt: pharmacometrics & systems pharmacology
IF0
err2026-07-07
err0
errOAAI
errFenja Klima; Anna M. Mc Laughlin; Robin Michelet; Wilhelm Huisinga; Katy Haussmann; Annette Künkele; Andrew C. Hooker; Charlotte Kloft
err分享
err收藏
Review of Existing Approaches and Potential Role of Pharmacometrics in the Interpretation of Prognostic Circulating Serum Biomarkers in Advanced NSCLC现有方法综述及药代动力学在解读晚期非小细胞肺癌预后性血清循环生物标志物中的作用
errClinical and Translational Science
IF2.8
err2026-03-08
err0
errOAAI
errFrancis Williams Ojara; Yomna M. Nassar; Kimberly Geiger; Madele van Dyk; Stefan Holdenrieder; Markus Joerger; Charlotte Kloft
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Therapeutic Drug Monitoring of Ustekinumab and Vedolizumab in IBD: Expanding Flexibility Through PK-PD Time-Based Thresholds炎症性肠病中乌司奴单抗和维得利珠单抗的治疗药物监测：通过基于药代动力学-药效学时间阈值提高灵活性
errJournal of Crohns & Colitis
IF8.7
err2026-01-01
err0
PREAI
errWidigson, E.; Frimor, C.; Duvnjak, Z.; Steenholdt, C.; Kjeldsen, J.; Husinga, W.; Weber, F.; Ainsworth, M. A.; Kloft, C.
err分享
err收藏
The protocol of an independant, randomized, controlled, danish, multicenter trial of Model-informed precision dosing of ustekinumab and vedolizumab in inflammatory bowel disease一项独立、随机、对照的丹麦多中心试验方案：炎症性肠病患者中他克珠单抗和维多珠单抗基于模型的精准给药研究
errJournal of Crohns & Colitis
IF8.7
err2026-01-01
err0
PREAI
errFrimor, C.; Steenholdt, C.; Widigson, E.; Larsen, L.; Burisch, J.; Jorgensen, M. T.; Halling, M.; Kloft, C.; Ainsworth, M. A.
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Therapeutic drug monitoring of ustekinumab and vedolizumab in Inflammatory Bowel Disease: A systematic review to define exposure thresholds for endoscopic remission乌司奴单抗和 vedolizumab 在炎症性肠病中的治疗药物监测：定义内镜缓解暴露阈值的系统评价
errJournal of Crohns & Colitis
IF8.7
err2026-01-01
err0
PREAI
errFrimor, C.; Widigson, E.; Steenholdt, C.; Duvnjak, Z.; Husinga, W.; Weber, F.; Kloft, C.; Ainsworth, M. A.
err分享
err收藏
Physiologically Motivated Sequential Population Modeling of Albumin Trends and Vedolizumab Pharmacokinetics for Pregnancy Dosing Regimen Optimization基于生理学驱动的序贯性群体模型对白蛋白趋势和 vedolizumab 药代动力学的建模，用于妊娠期给药方案优化
errClinical Pharmacology & Therapeutics
IF5.5
err2025-12-14
err0
errOAAI
errZrinka Duvnjak; Robin Michelet; Casper Steenholdt; Ella S.K. Widigson; Cæcilie Skejø; João A. Abrantes; Wilhelm Huisinga; Mette Julsgaard; Charlotte Kloft
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TLD-1, a Novel Liposomal Doxorubicin, in Patients with Solid Tumors: Comparative Pharmacokinetics and Final Results of a Multicenter Phase 1 Study (SAKK 65/16)TLD-1，一种新型脂质体多柔比星，在实体瘤患者中的比较药代动力学及一项多中心Ⅰ期研究（SAKK 65/16）的最终结果
errClinical Pharmacokinetics
IF4
err2025-11-18
err0
PREAI
errMarian Klose; Ilaria Colombo; Katrin Gobat; Kira-Lee Koster; Simon Haefliger; Manuela Rabaglio; Sara Bastian; Michael Schwitter; Ursina Zürrer-Härdi; Katrin Eckhardt; Stefanie Hayoz; Stefan Halbherr; Cristiana Sessa; Robin Michelet; Anna M. Mc Laughlin; Dagmar Hess; Anastasios Stathis; Charlotte Kloft; Markus Joerger
err分享
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The β-lactamase inhibitor concentration-dependent minimum inhibitory concentration (MICcBLI) as methodology to assess the pharmacokinetic/pharmacodynamic relationship of piperacillin/tazobactam for dosing optimizationβ-内酰胺酶抑制剂浓度依赖性最低抑菌浓度（MICcBLI）作为评估哌拉西林/他唑巴坦药代动力学/药效学关系以优化给药剂量的方法学
errJOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
IF3.6
err2025-11-01
err0
PREAI
errAndersson, Malin; Weber, Franz; Weinelt, Ferdinand; Zimmermann, Nicole; Jung, Jette; Zoller, Michael; Zander, Johannes; Huisinga, Wilhelm; Michelet, Robin; Kloft, Charlotte
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err收藏
Antibiotic pharmacodynamics: from MIC to advanced metrics and their applications抗菌药物药效学：从最低抑菌浓度到高级指标及其应用
errJOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
IF3.6
err2025-11-01
err1
PREAI
errAndersson, Malin; Zimmermann, Nicole; Kloft, Charlotte; Aulin, Linda B. S.
err分享
err收藏
Author’s Reply to Helsby and Hannam: ‘Understanding Voriconazole Metabolism: A Middle-Out Physiologically-Based Pharmacokinetic Modelling Framework Integrating In Vitro and Clinical Insights’作者对Helsby和Hannam的回复：‘理解伏立康唑代谢：一个整合体外和临床见解的中间-外生理基础药代动力学建模框架’
errClinical Pharmacokinetics
IF4
err2025-08-01
err0
errOAAI
errAyatallah Saleh; Josefine Schulz; Jan-Frederik Schlender; Linda B. S. Aulin; Amrei-Pauline Konrad; Franziska Kluwe; Gerd Mikus; Wilhelm Huisinga; Charlotte Kloft; Robin Michelet
err分享
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Predicting Residual 21-Hydroxylase Enzymatic Activity in Pediatric and Adult Congenital Adrenal Hyperplasia Patients: Towards Individualized Therapy预测儿科和成人先天性肾上腺皮质增生症患者残余21-羟化酶酶活性：迈向个体化治疗
errcpt pharmacometrics systems pharmacology
IF0
err2025-07-27
err0
errOAAI
errDavide Bindellini; Robin Michelet; Yersultan Mirasbekov; Qizong Lao; Charles Sukin; Wilhelm Huisinga; Deborah P. Merke; Charlotte Kloft
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Breaking barriers: The novel in vitro microdialysis system enables reproducing in vivo extraction efficiencies of linezolid突破壁垒：该新颖的体外微透析系统能够重现利奈唑胺的体内提取效率
errEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF4.7
err2025-06-01
err0
errOAAI
errMueller, Felix Leon; Bindellini, Davide; Mikus, Gerd; Michelet, Robin; Kloft, Charlotte
err分享
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The pharmacokinetics of antibiotics in patients with obesity: a systematic review and consensus guidelines for dose adjustments肥胖患者中抗生素的药代动力学：剂量调整的系统评价和共识指南
errThe Lancet Infectious Diseases
IF0
err2025-05-15
err0
PREAI
errAnne-Grete Märtson; Katie E Barber; Ryan L Crass; Maya Hites; Charlotte Kloft; Joseph L Kuti; Elisabet I Nielsen; Manjunath P Pai; Markus Zeitlinger; Jason A Roberts; Thomas Tängdén
err分享
err收藏
Model-informed identification of optimised dosing strategies for meropenem in critically ill patients receiving SLEDD: an observational study基于模型识别的危重症患者接受SLEDD治疗时美罗培南优化给药策略：一项观察性研究
errINFECTION
IF3.6
err2025-04-25
err0
errOAAI
errWeber, Franz; Scharf, Christina; Aulin, Linda B. S.; Weinelt, Ferdinand; Paal, Michael; Mikus, Gerd; Vogeser, Michael; Habler, Katharina; Huisinga, Wilhelm; Zoller, Michael; Michelet, Robin; Kloft, Charlotte; Liebchen, Uwe
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Impact of hemoadsorption with CytoSorb® on meropenem and piperacillin exposure in critically ill patients in a post-CKRT setup: a single-center, retrospective data analysis (Vol 13, 7, 2025)CytoSorb®血液吸附对连续肾脏替代疗法后危重患者美罗培南和哌拉西林暴露的影响：一项单中心回顾性数据分析（卷13，第7期，2025年）
errINTENSIVE CARE MEDICINE EXPERIMENTAL
IF3.1
err2025-03-03
err0
errOAAI
errAsgarpur, Golschan; Weber, Franz; Kiessling, Peggy; Akbari, Nilufar; Stroben, Fabian; Kleikamp, Bernadette; Kloft, Charlotte; Treskatsch, Sascha; Angermair, Stefan
err分享
err收藏
Hospitalised severe ulcerative colitis patients treated with rescue infliximab risk treatment failure due to underexposure caused by high drug clearance
errJOURNAL OF CROHNS & COLITIS
IF8.7
err2025-01-22
err0
PREAI
errDemaris, A.; Ovesen, P. D.; Ilvemark, J. F.; Seidelin, J. B.; Huisinga, W.; Michelet, R.; Steenholdt, C.; Kloft, C.
err分享
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Supporting vedolizumab treatment throughout pregnancy: Insights from a population pharmacokinetic model
errJOURNAL OF CROHNS & COLITIS
IF8.7
err2025-01-22
err0
PREAI
errDuvnjak, Z.; Steenholdt, C.; Skejo, C.; Baunwall, S. M. D.; Widigson, E. S. K.; Korgaard, J.; Klassen, R. A.; Bolstad, N.; Kjeldsen, J.; Poulsen, A.; Kievit, L.; Larsen, L.; Munkholm, P.; Svenningsen, L.; Haderslev, K., V; Wildt, S.; Vind, I; Kelsen, J.; Abrantes, J. A.; Michelet, R.; Huisinga, W.; Kloft, C.; Julsgaard, M.
err分享
err收藏
Forecasting antimicrobial resistance evolution
errTRENDS IN MICROBIOLOGY
IF14.9
err2024-08-01
err8
PREAI
errRolff, Jens; Bonhoeffer, Sebastian; Kloft, Charlotte; Leistner, Rasmus; Regoes, Roland; Hochberg, Michael E.
err分享
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Leveraging QSP Models for MIPD: A Case Study for Warfarin/INR
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2024-04-24
err2
errOAAI
errFalkenhagen, Undine; Cavallari, Larisa H.; Duarte, Julio D.; Kloft, Charlotte; Schmidt, Stephan; Huisinga, Wilhelm
err分享
err收藏

研究方向

暂无研究方向
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