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The potential of epigenetic therapy to target the 3D epigenome in endocrine-resistant breast cancer Achinger-Kawecka, Joanna; Stirzaker, Clare; Portman, Neil; Campbell, Elyssa; Chia, Kee-Ming; Du, Qian; Laven-Law, Geraldine; Nair, Shalima S.; Yong, Aliza; Wilkinson, Ashleigh; Clifton, Samuel; Milioli, Heloisa H.; Alexandrou, Sarah; Caldon, C. Elizabeth; Song, Jenny; Khoury, Amanda; Meyer, Braydon; Chen, Wenhan; Pidsley, Ruth; Qu, Wenjia; Gee, Julia M. W.; Schmitt, Anthony; Wong, Emily S.; Hickey, Theresa E.; Lim, Elgene; Clark, Susan J. 分享 收藏
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Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer Saunus, Jodi M.; De Luca, Xavier M.; Northwood, Korinne; Raghavendra, Ashwini; Hasson, Alexander; Reed, Amy E. McCart; Lim, Malcolm; Lal, Samir; Vargas, A. Cristina; Kutasovic, Jamie R.; Dalley, Andrew J.; Miranda, Mariska; Kalaw, Emarene; Kalita-de Croft, Priyakshi; Gresshoff, Irma; Al-Ejeh, Fares; Gee, Julia M. W.; Ormandy, Chris; Khanna, Kum Kum; Beesley, Jonathan; Chenevix-Trench, Georgia; Green, Andrew R.; Rakha, Emad A.; Ellis, Ian O.; Nicolau, Dan V., Jr.; Simpson, Peter T.; Lakhani, Sunil R. 分享 收藏
Vandetanib plus fulvestrant versus placebo plus fulvestrant after relapse or progression on an aromatase inhibitor in metastatic ER positive breast cancer (FURVA): A randomised, double-blind, placebo-controlled, phase II trial Jones, R.; Casbard, A.; Carucci, M.; Smith, J.; Ingarfield, K.; Gee, J. M. W.; Hudson, Z.; Alchami, F.; Hayward, L.; Hickish, T.; Hwang, D.; McAdam, K.; Spensley, S.; Waters, S.; Wheatley, D.; Beresford, M. 分享 收藏
The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis ZIP6/ZIP10异聚体对于锌介导的有丝分裂触发至关重要 Nimmanon, Thirayost; Ziliotto, Silvia; Ogle, Olivia; Burt, Anna; Gee, Julia M. W.; Andrews, Glen K.; Kille, Pete; Hogstrand, Christer; Maret, Wolfgang; Taylor, Kathryn M. 分享 收藏
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer Achinger-Kawecka, Joanna; Valdes-Mora, Fatima; Luu, Phuc-Loi; Giles, Katherine A.; Caldon, C. Elizabeth; Qu, Wenjia; Nair, Shalima; Soto, Sebastian; Locke, Warwick J.; Yeo-Teh, Nicole S.; Gould, Cathryn M.; Du, Qian; Smith, Grady C.; Ramos, Irene R.; Fernandez, Kristine F.; Hoon, Dave S.; Gee, Julia M. W.; Stirzaker, Clare; Clark, Susan J. 分享 收藏
Proliferation and AKT Activity Biomarker Analyses after Capivasertib (AZD5363) Treatment of Patients with ER+ Invasive Breast Cancer (STAKT) Robertson, John F. R.; Coleman, Robert E.; Cheung, Kwok-Leung; Evans, Abigail; Holcombe, Chris; Skene, Anthony; Rea, Daniel; Ahmed, Samreen; Jahan, Ali; Horgan, Kieran; Rauchhaus, Petra; Littleford, Roberta; Cheung, S. Y. Amy; Cullberg, Marie; de Bruin, Elza C.; Koulai, Loumpiana; Lindemann, Justin P. O.; Pass, Martin; Rugman, Paul; Schiavon, Gaia; Deb, Rahul; Finlay, Pauline; Foxley, Andrew; Gee, Julia M. W. 分享 收藏
PAK4 regulates sternness and progression in endocrine resistant ER-positive metastatic breast cancer PAK4调节内分泌耐药ER阳性转移性乳腺癌的sternness和进展 Santiago-Gomez, Angelica; Kedward, Thomas; Simoes, Bruno M.; Dragoni, Ilaria; NicAmhlaoibh, Roisin; Trivier, Elisabeth; Sabin, Verity; Gee, Julia M.; Sims, Andrew H.; Howell, Sacha J.; Clarke, Robert B. 分享 收藏
MicroRNA-196a is regulated by ER and is a prognostic biomarker in ER plus breast cancer Milevskiy, Michael J. G.; Gujral, Udai; Marques, Carolina Del Lama; Stone, Andrew; Northwood, Korinne; Burke, Lez J.; Gee, Julia M. W.; Nephew, Kenneth; Clark, Susan; Brown, Melissa A. 分享 收藏
Dose- and exposure-response relationship and biomarker correlation analysis in breast tumors from patients treated with capivasertib, an AKT inhibitor, in the STAKT randomized, placebo controlled pre-surgical study Gee, J.; Coleman, R. E.; Cheung, K. L.; Evans, A.; Holcombe, C.; Skene, A.; Rea, D.; Ahmed, S.; Jahan, A.; Horgan, K.; Rauchhaus, P.; Littleford, R.; Finlay, P.; Cheung, A.; Cullberg, M.; de Bruin, E.; Foxley, A.; Koulai, L.; Pass, M.; Schiavon, G.; Rugman, P.; Deb, R.; Robertson, J. F. R. 分享 收藏
Heregulin β1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells (vol 9, R50, 2007) Hutcheson, Iain R.; Knowlden, Janice M.; Hiscox, Steve E.; Barrow, Denise; Gee, Julia M. W.; Robertson, John F.; Ellis, Ian O.; Nicholson, Robert I. 分享 收藏
Acquired Resistance of ER-Positive Breast Cancer to Endocrine Treatment Confers an Adaptive Sensitivity to TRAIL through Posttranslational Downregulation of c-FLIP Piggott, Luke; Silva, Andreia; Robinson, Timothy; Santiago-Gomez, Angelica; Simoes, Bruno M.; Becker, Michael; Fichtner, Iduna; Andera, Ladislav; Young, Philippa; Morris, Christine; Barrett-Lee, Peter; Alchami, Fouad; Piva, Marco; Vivanco, Maria Dm; Clarke, Robert B.; Gee, Julia; Clarkson, Richard 分享 收藏
Long-range regulation of HOTAIR identifies novel biomarkers of breast cancer outcome and suggests a role in genome instability Milevskiy, Michael J.; Al-Ejeh, Fares; Saunus, Jodi M.; Northwood, Korinne S.; McCart-Reed, Amy E.; Dray, Eloise; Nephew, Kenneth; Bailey, Peter J.; Betts, Joshua A.; Stone, Andrew; Gee, Julia M. W.; Shewan, Annette M.; French, Juliet D.; Edwards, Stacey L.; Clark, Susan J.; Lakhani, Sunil R.; Brown, Melissa A. 分享 收藏
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Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer Milevskiy, Michael J. G.; Al-Ejeh, Fares; Saunus, Jodi M.; Northwood, Korinne S.; Bailey, Peter J.; Betts, Joshua A.; Reed, Amy E. McCart; Nephew, Kenneth P.; Stone, Andrew; Gee, Julia M. W.; Dowhan, Dennis H.; Dray, Eloise; Shewan, Annette M.; French, Juliet D.; Edwards, Stacey L.; Clark, Susan J.; Lakhani, Sunil R.; Brown, Melissa A. 分享 收藏
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