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Paul M. Loadman

institute of cancer therapeutics

43H指数
291论文数
5.3K被引数
收录论文 89
发表时间
Hypoxia-Responsive Prodrug of ATR Inhibitor, AZD6738, Selectively Eradicates Treatment-Resistant Cancer Cells
err2024-07-08
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errOAAI
errBarnieh, Francis M.; Morais, Goreti Ribeiro; Loadman, Paul M.; Falconer, Robert A.; El-Khamisy, Sherif F.
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A Phase I trial of AVA6000, a Fibroblast Activation Protein (FAP)-released and tumor microenvironment (TME)-targeted doxorubicin peptide drug conjugate in patients with FAP-positive solid tumors
err2024-04-05
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PREAI
errBanerji, Udai; Cook, Natalie; Anthoney, Alan; Plummer, Ruth; Tap, William D.; Evans, Jeffry T.; Cranmer, Lee D.; Plummer, Christopher; Loadman, Paul; Lahu, Gezim; Jones, Huw S.; Kinnersley, Nelson; McLaughlin, Fiona; Twelves, Chris
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Maleimide-Thiol Linkages Alter the Biodistribution of SN38 Therapeutic Microbubbles Compared to Biotin-Avidin While Preserving Parity in Tumoral Drug Delivery
err2024-03-21
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errOAAI
errIngram, Nicola; Abou-Saleh, Radwa H.; Race, Amanda D.; Loadman, Paul M.; Bushby, Richard J.; Evans, Stephen D.; Coletta, P. Louise
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Sidechain structure-activity relationships of cyclobutane-based small molecule αvβ3 antagonists
err2024-01-01
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errOAAI
errThroup, Adam; Zraikat, Manar Saleh; Gordon, Andrew; Jafarinejad Soumehsaraei, Shohreh; Haase, Kathrin D.; Patterson, Laurence H.; Cooper, Patricia A.; Hanlon, Katherine; Loadman, Paul M.; Sutherland, Mark; Shnyder, Steven D.; Sheldrake, Helen M.
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The effect of aspirin and eicosapentaenoic acid on urinary biomarkers of prostaglandin E2 synthesis and platelet activation in participants of the seAFOod polyp prevention trial
err2023-10-19
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errOAAI
errSun, Ge; Fuller, Harriett; Fenton, Hayley; Race, Amanda D.; Downing, Amy; Williams, Elizabeth A.; Rees, Colin J.; Brown, Louise C.; Loadman, Paul M.; Hull, Mark A.
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Colorectal polyp outcomes after participation in the seAFOod polyp prevention trial: Evidence of rebound elevated colorectal polyp risk after short-term aspirin use
err2023-07-30
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errOAAI
errDowning, Amy; Fenton, Hayley; Nickerson, Claire; Loadman, Paul M.; Williams, Elizabeth A.; Rees, Colin J.; Brown, Louise C.; Morris, Eva J. A.; Hull, Mark A.
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Targeted delivery of a colchicine analogue provides synergy with ATR inhibition in cancer cells
err2022-07-01
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errOAAI
errBarnieh, Francis M.; Morais, Goreti Ribeiro; Garland, Herbie; Loadman, Paul M.; Falconer, Robert A.
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A Single Short 'Tone Burst' Results in Optimal Drug Delivery to Tumours Using Ultrasound-Triggered Therapeutic Microbubbles
err2022-03-11
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errIngram, Nicola; McVeigh, Laura E.; Abou-Saleh, Radwa H.; Batchelor, Damien V. B.; Loadman, Paul M.; McLaughlan, James R.; Markham, Alexander F.; Evans, Stephen D.; Coletta, P. Louise
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Cytochrome P450 isoforms 1A1, 1B1 AND 2W1 as targets for therapeutic intervention in head and neck cancer
err2021-09-23
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errOAAI
errPresa, Daniela; Khurram, Syed A.; Zubir, Amir Z. A.; Smarakan, Sneha; Cooper, Patricia A.; Morais, Goreti R.; Sadiq, Maria; Sutherland, Mark; Loadman, Paul M.; McCaul, James; Shnyder, Steven D.; Patterson, Laurence H.; Pors, Klaus
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Luminal Bioavailability of Orally Administered ω-3 PUFAs in the Distal Small Intestine, and Associated Changes to the IIeal Microbiome, in Humans with a Temporary Ileostomy
err2021-08-01
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errOAAI
errNana, Gael; Mitra, Suparna; Watson, Henry; Young, Caroline; Wood, Henry M.; Perry, Sarah L.; Race, Amanda D.; Quirke, Philip; Toogood, Giles J.; Loadman, Paul M.; Hull, Mark A.
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Probing cytochrome P450 (CYP) bioactivation with chloromethylindoline bioprecursors derived from the duocarmycin family of compounds
err2021-06-01
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errOAAI
errOrtuzar, Natalia; Karu, Kersti; Presa, Daniela; Morais, Goreti R.; Sheldrake, Helen M.; Shnyder, Steve D.; Barnieh, Francis M.; Loadman, Paul M.; Patterson, Laurence H.; Pors, Klaus; Searcey, Mark
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An assay for quantitative analysis of polysialic acid expression in cancer cells
err2021-05-01
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PREAI
errGuo, Xiaoxiao; Elkashef, Sara M.; Patel, Anjana; Morais, Goreti Ribeiro; Shnyder, Steven D.; Loadman, Paul M.; Patterson, Laurence H.; Falconer, Robert A.
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How can the potential of the duocarmycins be unlocked for cancer therapy?
err2021-02-01
err21
PREAI
errJukes, Zoe; Morais, Goreti Ribeiro; Loadman, Paul M.; Pors, Klaus
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Optimizing the combination of the CDK4/6 inhibitor palbociclib and paclitaxel using cell cycle analysis
err2020-08-15
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PREAI
errSpencer, Jade A.; Race, Amanda D.; Cooper, Patricia A.; Shnyder, Steven D.; Loadman, Paul M.; Twelves, Christopher J.
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An efficient assay for identification and quantitative evaluation of potential polysialyltransferase inhibitors
errANALYST
IF3.3
err2020-01-01
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errOAAI
errGuo, Xiaoxiao; Malcolm, Jodie R.; Ali, Marrwa M.; Morais, Goreti Ribeiro; Shnyder, Steven D.; Loadman, Paul M.; Patterson, Laurence H.; Falconer, Robert A.
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Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting bioavailability and toxicity in normal tissues
err2020-01-01
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errOAAI
errIngram, Nicola; McVeigh, Laura E.; Abou-Saleh, Radwa H.; Maynard, Juliana; Peyman, Sally A.; McLaughlan, James R.; Fairclough, Michael; Marston, Gemma; Valleley, Elizabeth M. A.; Jimenez-Macias, Jorge L.; Charalambous, Antonia; Townley, William; Haddrick, Malcolm; Wierzbicki, Antonia; Wright, Alexander; Volpato, Milene; Simpson, Peter B.; Treanor, Darren E.; Thomson, Neil H.; Loadman, Paul M.; Bushby, Richard J.; Johnson, Benjamin R. G.; Jones, Pamela F.; Evans, J. Anthony; Freear, Steven; Markham, Alexander F.; Evans, Stephen D.; Coletta, P. Louise
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