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T

Thomas Jackson

University of Oxford
H指数:17
被引数:789

个人简介

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工作经历

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荣誉奖项

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Off-the-shelf dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal high-risk KMT2A-rearranged leukemia

现成的双CAR-iNKT细胞免疫疗法可清除髓内和软脑膜高风险KMT2A重排白血病

Blood
IF23.1
2025-09-040
OAAI
Hongwei Ren; Natalina Elliott; Bryan Lye; Mohammad Umer Sharif Shohan; Joe W. Cross; Lucy Field; Kanagaraju Ponnusamy; Siobhan Rice; Thomas Jackson; Ilia Leontari; Nouhad El Ouazzani; Rebecca Thomas; Sarah Inglott; Jack Bartram; Owen Smith; Jonathan Bond; Irene A. G. Roberts; Christina Halsey; Rachael Bashford-Rogers; Thomas A. Milne; Anindita Roy; Anastasios Karadimitris
Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression in patients

增强子异质性在急性淋巴细胞白血病中驱动患者间差异基因表达

Blood
IF23.1
2025-07-310
OAAI
Alastair L. Smith; Nicholas Denny; Catherine Chahrour; Kim Sharp; Marta Arachi; Ana M. Dopico-Fernandez; Natalina Elliott; Joe R. Harman; Thomas Jackson; Huimin Geng; Owen Smith; Jonathan Bond; Irene Roberts; Ronald W. Stam; Nicholas T. Crump; James O. J. Davies; Anindita Roy; Thomas A. Milne
PROM1/CD133 MARKS A PROLIFERATIVE STEM CELL LIKE POPULATION OF BLASTS IN KMT2A REARRANGED INFANT ALL

PROM1/CD133标记了KMT2A重排婴儿急性淋巴细胞白血病中的一种增殖性类干细胞blast群体。

Blood Advances
IF7.1
2025-07-050
OAAI
Joe Wilson Cross; Lucy Field; Alastair Smith; Emily Neil; Lucy Hamer; Thomas Jackson; Natalina Elliott; Siobhan Rice; Nicholas Crump; Joe Harman; Rebecca E. Ling; Qingqing Wu; Nouhad El Ouazzani; Rebecca Thomas; Sarah Inglott; Jack Bartram; Owen Smith; Jonathan Bond; Irene Roberts; Thomas A. Milne; Anindita Roy
Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia
RSC MEDICINAL CHEMISTRY
IF3.6
2024-01-011
OAAI
Cogswell, Thomas J.; Josa-Cullere, Laia; Zimmer, David; Galan, Sebastien R. G.; Jay-Smith, Morgan; Harris, Kate S.; Bataille, Carole J. R.; Jackson, Thomas R.; Zhang, Douzi; Davies, Stephen G.; Vyas, Paresh; Milne, Thomas A.; Wynne, Graham M.; Russell, Angela J.
Phenotypic screening identifies a trisubstituted imidazo[1,2-a]pyridine series that induces differentiation in multiple AML cell lines
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2023-10-013
PRE
Josa-Cullere, Laia; Galan, Sebastien R. G.; Cogswell, Thomas J.; Jackson, Thomas R.; Jay-Smith, Morgan; Mola, Laura; Greaves, Christopher R.; Carter, Tom S.; Madden, Katrina S.; Trott, Sophie; Zhang, Douzi; Bataille, Carole J. R.; Davies, Stephen G.; Vyas, Paresh; Milne, Thomas A.; Naylor, Alan; Wynne, Graham M.; Russell, Angela J.
A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program
NATURE COMMUNICATIONS
IF15.7
2021-11-2528
OAAI
Rice, Siobhan; Jackson, Thomas; Crump, Nicholas T.; Fordham, Nicholas; Elliott, Natalina; O'Byrne, Sorcha; Fanego, Maria del Mar Lara; Addy, Dilys; Crabb, Trisevgeni; Dryden, Carryl; Inglott, Sarah; Ladon, Dariusz; Wright, Gary; Bartram, Jack; Ancliff, Philip; Mead, Adam J.; Halsey, Christina; Roberts, Irene; Milne, Thomas A.; Roy, Anindita
The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis
NATURE COMMUNICATIONS
IF15.7
2021-02-0534
OAAI
Muskens, Ivo S.; Li, Shaobo; Jackson, Thomas; Elliot, Natalina; Hansen, Helen M.; Myint, Swe Swe; Pandey, Priyatama; Schraw, Jeremy M.; Roy, Ritu; Anguiano, Joaquin; Goudevenou, Katerina; Siegmund, Kimberly D.; Lupo, Philip J.; de Bruijn, Marella F. T. R.; Walsh, Kyle M.; Vyas, Paresh; Ma, Xiaomei; Roy, Anindita; Roberts, Irene; Wiemels, Joseph L.; de Smith, Adam J.
H3K79me2/3 controls enhancer-promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells
LEUKEMIA
IF13.4
2020-04-0240
OAAI
Godfrey, Laura; Crump, Nicholas T.; O'Byrne, Sorcha; Lau, I-Jun; Rice, Siobhan; Harman, Joe R.; Jackson, Thomas; Elliott, Natalina; Buck, Gemma; Connor, Christopher; Thorne, Ross; Knapp, David J. H. F.; Heidenreich, Olaf; Vyas, Paresh; Menendez, Pablo; Inglott, Sarah; Ancliff, Philip; Geng, Huimin; Roberts, Irene; Roy, Anindita; Milne, Thomas A.

研究方向

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T
Thomas A. Milne
H 指数:48论文数:253被引数:1.2万
A
Anindita Roy
H 指数:28论文数:158被引数:3,286
I
Irene Roberts
H 指数:74论文数:396被引数:2.4万
P
Paresh Vyas
H 指数:93论文数:622被引数:4.4万
N
Natalina Elliott
H 指数:11论文数:83被引数:981
P
Paul A. Townsend
H 指数:56论文数:302被引数:1.0万
N
Nicholas T. Crump
H 指数:16论文数:54被引数:1,839
A
Anda Huna
H 指数:19论文数:39被引数:998
S
Siobhan Rice
H 指数:9论文数:31被引数:550
J
Joe Harman
H 指数:10论文数:43被引数:643