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B

B. Krumm

University of North Carolina at Chapel Hill
H指数:30
被引数:3,979

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De novo design of miniproteins targeting GPCRs

从头设计靶向GPCRs的迷你蛋白

Nature
IF48.5
2026-05-210
PRE
Edin Muratspahić; David Feldman; David E. Kim; Xiangli Qu; Ana-Maria Bratovianu; Paula Rivera-Sánchez; Jan Hendrik Voss; Emil P. T. Hertz; Mads Jeppesen; Federica Dimitri; Kensuke Sakamoto; Amrita Nallathambi; Pia Peceli; Jianjun Cao; Brian P. Cary; Matthew J. Belousoff; Peter Keov; Phuc N. H. Trinh; Qingchao Chen; Yue Ren; Justyn Fine; Sudha Mishra; Annu Dalal; Shachie Sinha; Ramanuj Banerjee; Manisankar Ganguly; Karthik Varappalayam Karuppusamy; Isaac Sappington; Thomas Schlichthaerle; Jason Z. Zhang; Arvind Pillai; Brian Coventry; Ljubica Mihaljević; Magnus Bauer; Susana Vázquez Torres; Amir Motmaen; Gyu Rie Lee; Long Tran; Xinru Wang; Inna Goreshnik; Dionne K. Vafeados; Justin E. Svendsen; Parisa Hosseinzadeh; Nicolai Lindegaard; Matthäus Brandt; Yann Waltenspühl; Kristine Deibler; Lukas Deweid; Anja Bennett; Jendrik Schöppe; Tiantang Dong; Xiaoli Yan; Luke Oostdyk; William Cao; Lakshmi Anantharaman; Johan J. Weisser; Jesper Frank Bastlund; Christoffer Bundgaard; Ayodeji A. Asuni; Justin G. English; Lance Stewart; Lauren Halloran; Jamie B. Spangler; André Lieber; Arun K. Shukla; Patrick M. Sexton; Bryan L. Roth; Brian E. Krumm; Denise Wootten; Christopher G. Tate; Christoffer Norn; David Baker
Structure-based design of an opioid receptor modulator for enhanced morphine analgesia

基于结构的阿片受体调节剂的设计，以增强吗啡镇痛效果

Science Advances
IF12.5
2026-02-110
OA
Yue Wang; Ping Luo; Haiyan Xu; Li Zhan; Kensuke Sakamoto; Mingyu Li; Jing Wang; Xi-Ping Huang; Jianhui Zhou; Tao Liu; Yanrui Suo; Wenjia Fan; Xinheng He; Youwei Xu; Yongjie Cai; Chao Wang; Yuxi Zhao; Antao Dai; Yali Lai; Qingning Yuan; Wen Hu; Kai Wu; Dehua Yang; Xi Cheng; Xiaojie Lu; Brian Krumm; Terry Kenakin; Jian Zhang; Bryan L. Roth; Zhaobing Gao; H. Eric Xu; Youwen Zhuang
High-affinity agonists reveal recognition motifs for the MRGPRD GPCR

高亲和力激动剂揭示了MRGPRD GPCR的识别基序

CELL REPORTS
IF6.9
2024-12-010
OAAI
Wang, Chunyu; Liu, Yongfeng; Lanier, Marion; Yeager, Adam; Singh, Isha; Gumpper, Ryan H.; Krumm, Brian E.; Deleon, Chelsea; Zhang, Shicheng; Boehm, Marcus; Pittner, Richard; Baron, Alain; Dvorak, Lisa; Bacon, Corinne; Shoichet, Brain K.; Martinborough, Esther; Fay, Jonathan F.; Cao, Can; Roth, Bryan L.
A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state

神经发育障碍突变将g蛋白锁定在短暂的预激活状态

NATURE COMMUNICATIONS
IF15.7
2024-08-050
OAAI
Knight, Kevin M.; Krumm, Brian E.; Kapolka, Nicholas J.; Ludlam, W. Grant; Cui, Meng; Mani, Sepehr; Prytkova, Iya; Obarow, Elizabeth G.; Lefevre, Tyler J.; Wei, Wenyuan; Ma, Ning; Huang, Xi-Ping; Fay, Jonathan F.; Vaidehi, Nagarajan; Smrcka, Alan V.; Slesinger, Paul A.; Logothetis, Diomedes E.; Martemyanov, Kirill A.; Roth, Bryan L.; Dohlman, Henrik G.
Structural genomics of the human dopamine receptor system

人类多巴胺受体系统的结构基因组学

CELL RESEARCH
IF25.9
2023-05-2316
OA
Xu, Peiyu; Huang, Sijie; Krumm, Brian E.; Zhuang, Youwen; Mao, Chunyou; Zhang, Yumu; Wang, Yue; Huang, Xi-Ping; Liu, Yong-Feng; He, Xinheng; Li, Huadong; Yin, Wanchao; Jiang, Yi; Zhang, Yan; Roth, Bryan L.; Xu, H. Eric

研究方向

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B
Bryan L. Roth
H 指数:139论文数:981被引数:8.3万
黄
黄希
H 指数:71论文数:383被引数:2.7万
Y
Yongfeng Liu
H 指数:32论文数:172被引数:8,300
J
Jonathan F. Fay
H 指数:22论文数:68被引数:1,624
S
Shicheng Zhang
H 指数:15论文数:61被引数:1,223
H
H. Eric Xu
H 指数:100论文数:632被引数:4.0万
T
Tao Che
H 指数:34论文数:129被引数:6,954
J
Junpeng Deng
H 指数:29论文数:73被引数:2,391
R
Ryan H. Gumpper
H 指数:14论文数:43被引数:1,007
K
Kuglae Kim
H 指数:18论文数:55被引数:2,002