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收藏分享 收藏 分享 收藏 The novel lysophosphatidic acid receptor 1-selective antagonist, ACT-1016-0707, has unique binding properties that translate into effective antifibrotic and anti-inflammatory activity in different models of pulmonary fibrosis
Birker-Robaczewska, Magdalena; Boucher, Maxime; Ranieri, Giulia; Poirey, Sylvie; Studer, Rolf; Freti, Diego; Schnoebelen, Marie; Froidevaux, Sylvie; Morrison, Keith; Wyss, Conrad; Scherer, Jeremy; Lescop, Cyrille; Brotschi, Christine; Bolli, Martin H.; Kramberg, Markus; Di Stefano, Simone; Rey, Markus; Iglarz, Marc; Delahaye, Stephane; Vezzali, Enrico; Sieber, Patrick; Schafer, Anny; Caimi, Silvia L.; Hesse, Christina; Nayler, Oliver 分享 收藏 ACKR3 Antagonism Enhances the Repair of Demyelinated Lesions Through Both Immunomodulatory and Remyelinating EffectsPouzol, Laetitia; Sassi, Anna; Tunis, Melanie; Zurbach, Anais; Baumlin, Nadege; Gnerre, Carmela; Strasser, Daniel S.; Marrie, Julia; Vezzali, Enrico; Martinic, Marianne M. 分享 收藏 ACT-1004-1239, a first-in-class CXCR7 antagonist with both immunomodulatory and promyelinating effects for the treatment of inflammatory demyelinating diseasesPouzol, Laetitia; Baumlin, Nadege; Sassi, Anna; Tunis, Melanie; Marrie, Julia; Vezzali, Enrico; Farine, Herve; Mentzel, Ulrich; Martinic, Marianne M. 分享 收藏 Pharmacological Characterization of Aprocitentan, a Dual Endothelin Receptor Antagonist, Alone and in Combination with Blockers of the Renin Angiotensin System, in Two Models of Experimental HypertensionTrensz, Frederic; Bortolamiol, Celine; Kramberg, Markus; Wanner, Daniel; Hadana, Hakim; Rey, Markus; Strasser, Daniel S.; Delahaye, Stephane; Hess, Patrick; Vezzali, Enrico; Mentzel, Ulrich; Menard, Joel; Clozel, Martine; Iglarz, Marc 分享 收藏 
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