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Minimum information about a microarray experiment (MIAME) - toward standards for microarray data

delete2001-12-01
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A
Alvis Brāzma *
P
Pascal Hingamp
J
John Quackenbush
G
Gavin Sherlock
P
Paul T. Spellman
C
C. J. Stoeckert
J
John Aach
W
Wilhelm Ansorge
C
Catherine A. Ball
H
Helen C. Causton
T
Terry Gaasterland
P
Patrick Glenisson
F
Frank C. P. Holstege
I
Irene F. Kim
M
Markowitz, V
J
John C. Matese
H
Helen Parkinson
A
Alan J. Robinson
U
Uğis Sarkans
S
Steffen Schulze-Kremer
J
Jason Stewart
R
Ronald C. Taylor
J
Jaak Vilo
M
Martin Vingron
DOI:10.1038/ng1201-365delete
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Abstract

Abstract

En 中文
Microarray analysis has become a widely used tool for the generation of gene expression data on a genomic scale. Although many significant results have been derived from microarray studies, one limitation has been the lack of standards for presenting and exchanging such data. Here we present a proposal, the Minimum Information About a Microarray Experiment (MIAME), that describes the minimum information required to ensure that microarray data can be easily interpreted and that results derived from its analysis can be independently verified. The ultimate goal of this work is to establish a standard for recording and reporting microarray-based gene expression data, which will in turn facilitate the establishment of databases and public repositories and enable the development of data analysis tools. With respect to MIAME, we concentrate on defining the content and structure of the necessary information rather than the technical format for capturing it.
Keywords:
GENE-EXPRESSION
DNA ARRAYS
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Journal

Nature Reviews Endocrinology cover
Nature Reviews Endocrinology
IF:
40
Papers:
1.0W
Citations:
10.5W

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