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Novartis

Scholars1.8W
Papers9.5K
Citations2.9K
Related Papers (2896)
Publication Date
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DMPK Considerations for the Development of Covalent Drugs: Insights from an IQ Assessment
errJournal of Medicinal Chemistry
IF6.8
err2026-04-28
err0
PREAI
errJulian Dopstadt; Kamelia Behnia; Xiaoming Cui; Nicola Colclough; Martin Dowty; Julius Enoru; Robert S. Foti; Felix Huth; Frank Jacobs; Rohitash Jamwal; Benjamin M. Johnson; Shyam Kamble; Julie Lade; Sandhya Mandlekar; Hlaing Holly Maw; Kowser Miah; Mike Mohutsky; Holger Scheible; Hao Sun; Shuai Wang; Matthias Beat Wittwer; Sean Xiaochun Zhu; Stefanie Zimmermann; Rowan Stringer
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A first-in-human phase 1 clinical study in healthy volunteers to assess the safety, tolerability and pharmacokinetics of EDI048, a novel promising agent to treat enteric cryptosporidiosis
errThe Journal of Infectious Diseases
IF0
err2026-04-10
err0
errOAAI
errMonish Jain; Kristen Stevenson; Anais Cheblal; Ganesh Iyer; Rahmanzadeh Gholamreza; Jean-Rene Galarneau; Sofia Braud-Perez; Rajiv Jumani; Johanne Blais; Joseph Etse; Juergen Dederichs; Yiming Zhang; Kriti Arora; Robert K Beecham; William Prince; Ujjini H Manjunatha; Bridget D Stuart; null
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errSave
Discovery of EGT710; an Oral Nonpeptidomimetic Reversible Covalent SARS-CoV-2 Main Protease Inhibitor
errJournal of Medicinal Chemistry
IF6.8
err2026-02-09
err0
PREAI
errJulien P. N. Papillon; Jun Yuan; Matthew J. Hesse; Lei Zhang; Richard I. Robinson; Nathaniel F. Ware; Viktor Hornak; Rajeshri G. Karki; Tom Kirrane; Keira Garland; Sajan Joseph; Stephanie A. Moquin; Suresh B. Lakshminarayana; Laura Tandeske; Dustin Dovala; Mark Knapp; Elizabeth Ornelas; Daniel Fuller; Pei-i Ho; Xuping Xie; Katarina Vulic; Suzanne M. Skolnik; Jinhai Gao; Mark Zambrowski; Meike Spiess; José S. Duca; Scott A. Busby; Markus Schirle; Michael Robinson; Pei-Yong Shi; Heinz E. Moser; Christopher Sarko; James E. Bradner; Thierry T. Diagana; John A. Tallarico
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FIH Dose Selection Beyond MABEL: Optimizing Phase 1 clinical trial Starting Dose Whilst Protecting Patient Safety
errRegulatory Toxicology and Pharmacology
IF3.5
err2026-01-30
err0
PREAI
errMineo Matsumoto; J.Ryan Polli; Suresh Swaminathan; Kaushik Datta; Cris Kamperschroer; Marie C. Fortin; Smita Salian-Mehta; Rutwij Dave; Zheng Yang; Payal Arora; Masanori Hiura; Mizuho Suzuki; Christine E. Crute; Frank R. Brennan; Jean Sathish
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Efficacy and safety of inclisiran in adolescents with heterozygous familial hypercholesterolaemia (ORION-16): a two-part, randomised, multicentre clinical trial
errThe Lancet Diabetes & Endocrinology
IF41.8
err2026-01-27
err0
PREAI
errAlbert Wiegman; Amy L Peterson; Eric Bruckert; Joep C Defesche; Anja Schweizer; Jean Bergeron; María J Chueca; Jeanine E Roeters van Lennep; Raul D Santos; Karl Otfried Schwab; Anastasia Lesogor; Sijia Zhang; Robert A Hegele
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A budget impact model for biosimilar denosumab for skeletal-related events and fractures in the United States oncology population
errJOURNAL OF MEDICAL ECONOMICS
IF3
err2025-12-31
err0
PREAI
errFlanigan, Jeanine; Chaplin, Stephen; van Stiphout, Joris; Schauf, Marion; Tindal, Mike; Gundlach, Andrea; Li, Edward; Lyman, Gary H.
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Fully Liquid Phase Oligonucleotide Synthesis
errORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
err2025-12-01
err0
PREAI
errGaffney, Piers R. J.; Jarrett-Wilkins, Charles; Yeo, Jet; Nylander, Christina; Mansha, Kinza; Mukadam, Aneesah; Gupta, Lekha; Akbar, Sharmin; Jahan, Builqis; Li Volsi, Anna; Pember-Jones, Aaron; So, Jerry; Murphy, Niall; Rupsys, Eligijus; Oxley, Adam; Pypec, Maxime; Bertulli, Cristina; Felines, Nicolas; O'Brien, Dara M.; Di Silvestro, Alfredo; Ray, Bidisha; Cuccato, Danilo; Khalily, Mohammad Aref; Madugundu, Guru S.; Pereira, Ines; Moore, Daniel N.; Kleczewska, Natalia; Cook, Marcus; Diorazio, Louis J.; Telford, Alex; Benstead, David; Radinov, Roumen; Brooks, Joshua; Nechev, Lubomir V.; Parga, Catalina; Venturoni, Francesco; Haber, Julien; MacLeod, Claire; Cassey, Barrie; Sutherland, Euan; Walton, Heather P.; Livingston, Andrew G.
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MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony
errNature Methods
IF32.1
err2025-11-13
err0
PREAI
errGangadhar Eluru; Steven De Gieter; Stephan Schenck; Annelore Stroobants; Binesh Shrestha; Paul Erbel; Janine D. Brunner; Rouslan G. Efremov
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Predicting long-term benefits of improvements in estimated glomerular filtration rate (eGFR) with iptacopan on delaying kidney failure in complement 3 glomerulopathy (C3G)
errNephrology Dialysis Transplantation
IF5.6
err2025-10-01
err0
errOAAI
errCouncil, Novartis Renal; Sidhu, Raisa; Smeets, Serge; Proudfoot, Clare; Ndife, Briana; Woodcock, Fionn
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errSave
Changes in health behaviors and cardiovascular disease: a register-linkage study in Finland
errEUROPEAN JOURNAL OF PUBLIC HEALTH
IF3.9
err2025-10-01
err0
PREAI
errHarkko, J.; Pietilainen, O.; Jousilahti, P.; Etholen, A.; Vahasarja, L.; Teppo, E.; Boch, J.; Speyer, P.; Lallukka, T.
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errSave
Contribution of health behaviours to cardiovascular disease by socioeconomic position in Finland
errEUROPEAN JOURNAL OF PUBLIC HEALTH
IF3.9
err2025-10-01
err0
errOAAI
errPietilaeinen, O.; Vaehaesarja, L.; Etholen, A.; Teppo, E.; Boch, J.; Speyer, P.; Jousilahti, P.; Harkko, J.; Lallukka, T.
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Burden of illness in chronic primary glomerulonephritis: the patient perspective
errNephrology Dialysis Transplantation
IF5.6
err2025-10-01
err0
errOAAI
errFontan, Fernando Caravaca; Aris, Alvaro Madrid; Moreno, Marta; Jorge, Marian Vidal; Nafissi, Julieta; Terente, Manuel Praga
errShare
errSave
Skeletal Muscle Biomarkers of Amyotrophic Lateral Sclerosis: A Large-Scale, Multi-Cohort Proteomic Study
errANNALS OF NEUROLOGY
IF7.7
err2025-09-01
err0
PREAI
errDergai, Oleksandr; Wuu, Joanne; Koziczak-Holbro, Magdalena; Malaspina, Andrea; Granit, Volkan; Hernandez, Jessica P.; Cooley, Anne; Sachdev, Ruchika; Yu, Lili; Bidinosti, Michael; Flotte, Ludivine; Nash, Mark; Jennings, Lori L.; Berry, James D.; Bruijn, Lucie I.; Brachat, Sophie; Benatar, Michael
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Frequency, diagnosis, and management of polymyalgia rheumatica in Germany-database analysis of medical insurance data
errRHEUMATOLOGY
IF4.4
err2025-07-01
err1
PREAI
errSchmidt, Wolfgang A.; Alibone, Marco; Ludwig, Paul; Obermueller, Dominik; Karl, Franziska; Terner, Stephanie; Venhoff, Nils
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Evaluation of various experimental conditions and mechanistic static versus dynamic models to predict time-dependent CYP3A4/5 inhibition potential of drugs
errDrug Metabolism and Disposition
IF4
err2025-06-27
err0
PREAI
errBadée Justine; Gu Helen; Huth Felix; Poller Birk; Schiller Hilmar; Chenal Gaëlle; Streckfuss Judith; Birlinger Bertrand-Luc; Deshmukh Sujal; Einolf J. Heidi
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HaloPROTAC3 does not trigger the degradation of the halotagged parasitophorous vacuole membrane protein UIS4 during Plasmodium liver stage development
errSCIENTIFIC REPORTS
IF3.9
err2025-05-26
err0
errOAAI
errLam, Melanie; Probst, Alexandra; Torres, Laura; Lantigua, Ashley A.; Fishbaugher, Matthew E.; Kumar, Jyothsna R.; Saldivia, Manuel; Torres, Allison; Hegde, Shreeya; Aleshnick, Maya; Jennison, Charlie; Roberson, Sarah G. H.; Joyner, Chester J.; Vaughan, Ashley M.; Wilder, Brandon K.; Manneville, Carole; Flannery, Erika L.; Marcellin, David; Nyfeler, Beat; Thiel, Zacharias; Mikolajczak, Sebastian A.; Harupa, Anke; Mitchell, Gabriel
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Prediction of cardiovascular risk: validation of a non-laboratory and a laboratory-based score in a Brazilian community-based cohort of the PURE study
errLANCET REGIONAL HEALTH-AMERICAS
IF7.6
err2025-03-01
err0
PREAI
errOliveira, Gustavo Bernardes de Figueiredo; Nunes, Rafael Amorim Belo; Alves, Lucas Bassolli de Oliveira; Neves, Precil Diego Miranda de Menezes; Sato, Victor Augusto Hamamoto; Triboni, Ana Heloisa Kamada; de Oliveira Junior, Haliton Alves; da Rosa, Priscila Raupp; Diaz, Maria Luz; Lopez-Jaramillo, Jose Patricio; Lanas, Fernando; Joseph, Philip; Avezum, Alvaro
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Designing and developing a prescription digital therapeutic for at-home heart rate variability biofeedback to support and enhance patient outcomes in post-traumatic stress disorder treatment
errFRONTIERS IN DIGITAL HEALTH
IF3.8
err2025-02-11
err0
errOAAI
errMacy, Rebecca; Somanji, Flavio; Sverdlov, Oleksandr
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errSave
Assessing the Adjuvant Potential of Chinese Hamster Ovary Host Cell Proteins Using an In Vitro Dendritic Cell Assay
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2025-02-10
err1
PREAI
errPanikulam, Sherin; Morgan, Hannah; Gutknecht, Michael; Karle, Anette; Rajaratnam, Atchaya; Muntwyler, Jennifer; Anderka, Oliver; Lebesgue, Nicolas; Villiger, Thomas K.
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Rational design and analytical characterization of self-assembling poly (N-isopropylacrylamide) and poly(2-alkyl-2-oxazoline) hyaluronic acid copolymers
errINTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
err2025-02-01
err0
errOAAI
errBonelli, Mirko; Allemann, Eric; Di Stefano, Mauro
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