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M

Martin Empting

Helmholtz Institute for Pharmaceutical Research Saarland

33H-index
117Paper Count
4.1KCitation Count
Published Papers 57
Publication Date
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Identification of a new protein-RNA interaction inhibitor targeting the KH34 region of the Insulin-Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2/IMP2)
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-02-04
err0
PREAI
errAylin Berwanger; Konrad Wagner; Simon Both; Andreas M. Kany; Kyana Mazlom; Anna K.H. Hirsch; Alexandra K. Kiemer; Martin Empting
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Toward Anti-Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen
errCHEMMEDCHEM
IF3.4
err2025-11-01
err0
errOAAI
errBerwanger, Aylin; Stein, Saskia Catherina; Brandner, Sarah; Kany, Andreas Martin; Heinz, Sebastian; Loretz, Brigitta; Lehr, Claus-michael; Hirsch, Anna Katharina Herta; Lermyte, Frederik; Schulz, Thomas Friedrich; Empting, Martin
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Tandem ketone reduction in pepstatin biosynthesis reveals an F420H2-dependent statine pathway
errNATURE COMMUNICATIONS
IF15.7
err2025-05-15
err0
errOAAI
errMo, Jingjun; Sikandar, Asfandyar; Zhao, Haowen; Bashiri, Ghader; Huo, Liujie; Empting, Martin; Mueller, Rolf; Fu, Chengzhang
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Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality
errCell Genomics
IF9
err2025-05-09
err0
errOAAI
errChelsea E. Cunningham; Frederick S. Vizeacoumar; Yue Zhang; Liliia Kyrylenko; Simon Both; Vincent Maranda; He Dong; Jared D.W. Price; Peng Gao; Konrad Wagner; Yingwen Wu; Mary Lazell-Wright; Ashtalakshmi Ganapathysamy; Rithik Hari; Kalpana K. Bhanumathy; Connor Denomy; Anjali Saxena; Jeff P. Vizeacoumar; Alain Morejon Morales; Faizaan Khan; Shayla Mosley; Angie Chen; Tetiana Katrii; Ben G.E. Zoller; Karthic Rajamanickam; Prachi Walke; Lihui Gong; Hardikkumar Patel; Hussain Elhasasna; Renuka Dahiya; Omar Abuhussein; Anton Dmitriev; Tanya Freywald; Erika Prando Munhoz; Eytan Ruppin; Joo Sang Lee; Katharina Rox; Martin Koebel; Laura Hopkins; Cheng Han Lee; Sunil Yadav; Gilles Gasparoni; Jörn Walter; Anand Krishnan; Raju Datla; Behzad Toosi; Kristi Baker; Jalna Meens; David W. Cescon; Laurie Ailles; Scot C. Leary; Yuliang Wu; Martin Empting; Alexandra K. Kiemer; Andrew Freywald; Franco J. Vizeacoumar
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Native Taylor/Non-Taylor Dispersion-Mass Spectrometry (TNT-MS) Allows Rapid Protein Desalting and Multiplexed, Label-Free Ligand Screening
errSMALL METHODS
IF9.1
err2025-05-07
err0
errOAAI
errEisert, Jonathan; Maciel, Edvaldo Vasconcelos Soares; Dederer, Verena; Berwanger, Aylin; Bailey, Henry J.; Dikic, Ivan; Knapp, Stefan; Empting, Martin; Mathea, Sebastian
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Domain adaptable language modeling of chemical compounds identifies potent pathoblockers for Pseudomonas aeruginosa
errCOMMUNICATIONS CHEMISTRY
IF6.2
err2025-04-11
err0
errOAAI
errKallergis, Georgios; Asgari, Ehsannedin; Empting, Martin; Hirsch, Anna K. H.; Klawonn, Frank; Mchardy, Alice C.
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The HIPS 2024 symposium: highlighting advances in pharmaceutical sciences in infection research
errTRENDS IN MICROBIOLOGY
IF14.9
err2024-10-01
err0
PREAI
errMayoka, Godfrey; Krug, Daniel; Loretz, Brigitta; Bozhueyuek, Kenan; Empting, Martin; Hirsch, Anna K. H.; Mueller, Rolf
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Discovery and optimization of thiazole-based quorum sensing inhibitors as potent blockers of Pseudomonas aeruginosa pathogenicity
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-10-01
err0
errOAAI
errAbdelsamie, Ahmed S.; Hamed, Mostafa M.; Schuetz, Christian; Roehrig, Teresa; Kany, Andreas M.; Schmelz, Stefan; Blankenfeldt, Wulf; Hirsch, Anna K. H.; Hartmann, Rolf W.; Empting, Martin
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Nanoparticles in liposomes: a platform for increased antibiotic selectivity in multidrug resistant bacteria in respiratory tract infections
errDRUG DELIVERY AND TRANSLATIONAL RESEARCH
IF5.5
err2024-07-24
err0
errOAAI
errFakhoury, Nathalie E.; Mansour, Samar; Abdel-Halim, Mohammad; Hamed, Mostafa M.; Empting, Martin; Boese, Annette; Loretz, Brigitta; Lehr, Claus-Michael; Tammam, Salma N.
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Enzyme-Linked Lipid Nanocarriers for Coping Pseudomonal Pulmonary Infection. Would Nanocarriers Complement Biofilm Disruption or Pave Its Road?
errINTERNATIONAL JOURNAL OF NANOMEDICINE
IF6.5
err2024-04-01
err1
errOAAI
errNafee, Noha; Gaber, Dina M.; Abouelfetouh, Alaa; Alseqely, Mustafa; Empting, Martin; Schneider, Marc
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Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor
errNATURE COMMUNICATIONS
IF15.7
err2024-02-08
err6
errOAAI
errSake, Svenja M.; Zhang, Xiaoyu; Rajak, Manoj Kumar; Urbanek-Quaing, Melanie; Carpentier, Arnaud; Gunesch, Antonia P.; Grethe, Christina; Matthaei, Alina; Rueckert, Jessica; Galloux, Marie; Larcher, Thibaut; Le Goffic, Ronan; Hontonnou, Fortune; Chatterjee, Arnab K.; Johnson, Kristen; Morwood, Kaycie; Rox, Katharina; Elgaher, Walid A. M.; Huang, Jiabin; Wetzke, Martin; Hansen, Gesine; Fischer, Nicole; Eleouet, Jean-Francois; Rameix-Welti, Marie-Anne; Hirsch, Anna K. H.; Herold, Elisabeth; Empting, Martin; Lauber, Chris; Schulz, Thomas F.; Krey, Thomas; Haid, Sibylle; Pietschmann, Thomas
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Gene Editing and Small Molecule Inhibitors of the RNA Binding Protein IGF2BP2/IMP2 Show its Potential as an Anti-Cancer Drug Target
errFRONTIERS IN BIOSCIENCE-LANDMARK
IF3.1
err2024-01-23
err4
errOAAI
errChanda, Shilpee; Lepikhov, Konstantin; Dahlem, Charlotte; Schymik, Hanna S.; Hoppstaedter, Jessica; Geber, An-Kristin; Wagner, Konrad; Kessler, Sonja M.; Empting, Martin; Kiemer, Alexandra K.
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Disrupting Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Latent Replication with a Small Molecule Inhibitor
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-07-28
err3
errOAAI
errBerwanger, Aylin; Stein, Saskia C.; Kany, Andreas M.; Gartner, Melissa; Loretz, Brigitta; Lehr, Claus-Michael; Hirsch, Anna K. H.; Schulz, Thomas F.; Empting, Martin
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Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle
errADVANCED SCIENCE
IF14.1
err2023-01-03
err13
errOAAI
errHamed, Mostafa M.; Abdelsamie, Ahmed S.; Rox, Katharina; Schuetz, Christian; Kany, Andreas M.; Roehrig, Teresa; Schmelz, Stefan; Blankenfeldt, Wulf; Arce-Rodriguez, Alejandro; Borrero-de Acuna, Jose Manuel; Jahn, Dieter; Rademacher, Jessica; Ringshausen, Felix C.; Cramer, Nina; Tuemmler, Burkhard; Hirsch, Anna K. H.; Hartmann, Rolf W.; Empting, Martin
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Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2022-12-20
err5
errOAAI
errSake, Svenja M.; Kosch, Christina; Blockus, Sebastian; Haid, Sibylle; Gunesch, Antonia P.; Zhang, Xiaoyu; Friesland, Martina; Trummer, Sofie B.; Grethe, Christina; Kuehnel, Anne; Rueckert, Jessica; Duprex, W. Paul; Huang, Jiabin; Rameix-Welti, Marie-Anne; Empting, Martin; Fischer, Nicole; Hirsch, Anna K. H.; Schulz, Thomas F.; Pietschmann, Thomas
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Modeling the Effect of Hydrophobicity on the Passive Permeation of Solutes across a Bacterial Model Membrane
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2022-10-10
err6
PREAI
errSousa, Carla F.; Kamal, Mohamed A. M.; Richter, Robert; Elamaldeniya, Kalanika; Hartmann, Rolf W.; Empting, Martin; Lehr, Claus-Michael; V. Kalinina, Olga
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NMR Experiments Provide Insights into Ligand-Binding to the SARS-CoV-2 Spike Protein Receptor-Binding Domain
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2022-07-13
err12
PREAI
errCreutznacher, Robert; Maass, Thorben; Veselkova, Barbora; Ssebyatika, George; Krey, Thomas; Empting, Martin; Tautz, Norbert; Frank, Martin; Kolbel, Knut; Uetrecht, Charlotte; Peters, Thomas
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Phage display-based discovery of cyclic peptides against the broad spectrum bacterial anti-virulence target CsrA
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2022-03-01
err7
errOAAI
errJakob, Valentin; Zoller, Ben G. E.; Rinkes, Julia; Wu, Yingwen F.; Kiefer, Alexander; Hust, Michael; Polten, Saskia M.; White, Andrew J.; Harvey, Peta; Durek, Thomas J.; Craik, David; Siebert, Andreas; Kazmaier, Uli; Empting, Martin
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First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy
errACS CHEMICAL BIOLOGY
IF3.8
err2022-01-13
err38
PREAI
errDahlem, Charlotte; Abuhaliema, Ali; Kessler, Sonja M.; Kroehler, Tarek; Zoller, Ben G. E.; Chanda, Shilpee; Wu, Yingwen; Both, Simon; Mueller, Fabian; Lepikhov, Konstantin; Kirsch, Susanne H.; Laggai, Stephan; Muller, Rolf; Empting, Martin; Kiemer, Alexandra K.
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Transferring Microclusters of P. aeruginosa Biofilms to the Air- Liquid Interface of Bronchial Epithelial Cells for Repeated Deposition of Aerosolized Tobramycin
errACS INFECTIOUS DISEASES
IF3.8
err2021-12-17
err10
errOAAI
errHorstmann, Justus C.; Laric, Annabelle; Boese, Annette; Yildiz, Daniela; Rohrig, Teresa; Empting, Martin; Frank, Nicolas; Krug, Daniel; Mueller, Rolf; Schneider-Daum, Nicole; Carvalho-Wodarz, Cristiane De Souza; Lehr, Claus-Michael
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Research Directions

No research directions
Co-authors
Cooperation Journals
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H-index: 119 · Papers: 506
P
Patrick Couvreur
H-index: 118 · Papers: 753
D
David J. Craik
H-index: 113 · Papers: 1.4K
S
Stefan Knapp
H-index: 111 · Papers: 1.3K
J
Jörg Vogel
H-index: 103 · Papers: 327
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