Not logged in Bitopic inhibitors of mTORC1 cooperate with inhibitors of mitogen-activated protein kinase kinase to drive cytotoxicity in glioblastoma Fan, Qiwen; Koach, Jessica; Luo, Karen; Clark, Sydney; Reddy, Shruthi; Ozawa, Tomoko; Wang, Linyu; Yoda, Hiroyuki; Sale, Matthew; Mccormick, Frank; Raleigh, David R.; Gustafson, William C.; Meyerowitz, Justin; Singh, Mallika; Berger, Mitchel; Shokat, Kevan M.; Weiss, William A. Share Save
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Aurora Kinase A inhibition enhances DNA damage and tumor cell death with 131I-MIBG therapy in high-risk neuroblastoma Kumar, Prerna; Koach, Jessica; Nekritz, Erin; Mukherjee, Sucheta; Braun, Benjamin S.; Dubois, Steven G.; Nasholm, Nicole; Haas-Kogan, Daphne; Matthay, Katherine K.; Weiss, William A.; Gustafson, Clay; Seo, Youngho Share Save
MYC phase separation selectively modulates the transcriptome ( may , 10.1038/s41594-024-01322-6, 2024) Yang, Junjiao; Chung, Chan-, I; Koach, Jessica; Liu, Hongjiang; Navalkar, Ambuja; He, Hao; Ma, Zhimin; Zhao, Qian; Yang, Xiaoyu; He, Liang; Mittag, Tanja; Shen, Yin; Weiss, William A.; Shu, Xiaokun Share Save
MYC phase separation selectively modulates the transcriptome Yang, Junjiao; Chung, Chan-, I; Koach, Jessica; Liu, Hongjiang; Navalkar, Ambuja; He, Hao; Ma, Zhimin; Zhao, Qian; Yang, Xiaoyu; He, Liang; Mittag, Tanja; Shen, Yin; Weiss, William A.; Shu, Xiaokun Share Save
The synergy of BET inhibitors with aurora A kinase inhibitors in MYCN-amplified neuroblastoma is heightened with functional TP53 Yi, Joanna S.; Sias-Garcia, Oscar; Nasholm, Nicole; Hu, Xiaoyu; Iniguez, Amanda Balboni; Hall, Matthew D.; Davis, Mindy; Guha, Rajarshi; Moreno-Smith, Myrthala; Barbieri, Eveline; Duong, Kevin; Koach, Jessica; Qi, Jun; Bradner, James E.; Stegmaier, Kimberly; Weiss, William A.; Gustafson, W. Clay Share Save
An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability Nagy, Zsuzsanna; Seneviratne, Janith A.; Kanikevich, Maxwell; Chang, William; Mayoh, Chelsea; Venkat, Pooja; Du, Yanhua; Jiang, Cizhong; Salib, Alice; Koach, Jessica; Carter, Daniel R.; Mittra, Rituparna; Liu, Tao; Parker, Michael W.; Cheung, Belamy B.; Marshall, Glenn M. Share Save
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Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface Koach, Jessica; Holien, Jessica K.; Massudi, Hassina; Carter, Daniel R.; Ciampa, Olivia C.; Herath, Mika; Lim, Taylor; Seneviratne, Janith A.; Milazzo, Giorgio; Murray, Jayne E.; McCarroll, Joshua A.; Liu, Bing; Mayoh, Chelsea; Keenan, Bryce; Stevenson, Brendan W.; Gorman, Michael A.; Bell, Jessica L.; Doughty, Larissa; Huettelmaier, Stefan; Oberthuer, Andre; Fischer, Matthias; Gifford, Andrew J.; Liu, Tao; Zhang, Xiaoling; Zhu, Shizhen; Gustafson, W. Clay; Haber, Michelle; Norris, Murray D.; Fletcher, Jamie I.; Perini, Giovanni; Parker, Michael W.; Cheung, Belamy B.; Marshall, Glenn M. Share Save
Alyref is a novel binding partner and co-factor for MYCN-driven oncogenesis in neuroblastoma Nagy, Zsuzsanna; Kanikevichi, Maxwell; Koachi, Jessica; Mayoh, Chelsea; Carter, Daniel; Liu, Tao; Du, Yanhua; Jiang, Cizhong; Haber, Michelle; Norris, Murray; Cheung, Belamy; Marshall, Glenn Share Save
MYCN and TFAP4 promote neuroblastoma malignancy by cooperating in the regulation a subset of target genes involved in cancer cell growth and metastasis Xue, Chengyuan; Yu, Denise M.; Gherardi, Samuele; Koach, Jessica; Milazzo, Giorgio; Gamble, Laura; Liu, Bing; Russell, Amanda; Liu, Tao; Cheung, Belamy B.; Marshall, Glenn M.; Perini, Giovanni; Haber, Michelle; Norris, Murray D. Share Save
Targeting PA2G4, a novel MYCN co-factor, for the treatment of neuroblastoma Koach, J.; Murray, J. E.; McCarroll, J.; Milazzo, G.; Perini, G.; Haber, M.; Norris, M. D.; Fletcher, J. I.; Cheung, B. B.; Marshall, G. M. Share Save
Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma Carter, Daniel R.; Murray, Jayne; Cheung, Belamy B.; Gamble, Laura; Koach, Jessica; Tsang, Joanna; Sutton, Selina; Kalla, Heyam; Syed, Sarah; Gifford, Andrew J.; Issaeva, Natalia; Biktasova, Asel; Atmadibrata, Bernard; Sun, Yuting; Sokolowski, Nicolas; Ling, Dora; Kim, Patrick Y.; Webber, Hannah; Clark, Ashleigh; Ruhle, Michelle; Liu, Bing; Oberthuer, Andre; Fischer, Matthias; Byrne, Jennifer; Saletta, Federica; Thwe, Le Myo; Purmal, Andrei; Haderski, Gary; Burkhart, Catherine; Speleman, Frank; De Preter, Katleen; Beckers, Anneleen; Ziegler, David S.; Liu, Tao; Gurova, Katerina V.; Gudkov, Andrei V.; Norris, Murray D.; Haber, Michelle; Marshall, Glenn M. Share Save
PA2G4 predicts poor prognosis in neuroblastoma patients and promotes neuroblastoma progression by enhancing MYCN protein stability Koach, Jessica; Liu, Bing; Bell, Jessica L.; Huettelmaier, Stefan; Liu, Tao; Carter, Daniel R.; Haber, Michelle; Norris, Murray D.; Fletcher, Jamie; Cheung, Belamy B.; Marshall, Glenn M. Share Save
Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma Cheung, Belamy B.; Tan, Owen; Koach, Jessica; Liu, Bing; Shum, Michael S. Y.; Carter, Daniel R.; Sutton, Selina; Po'uha, Sela T.; Chesler, Louis; Haber, Michelle; Norris, Murray D.; Kavallaris, Maria; Liu, Tao; O'Neill, Geraldine M.; Marshall, Glenn M. Share Save
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The histone deacetylase SIRT2 stabilizes Myc oncoproteins Liu, P. Y.; Xu, N.; Malyukova, A.; Scarlett, C. J.; Sun, Y. T.; Zhang, X. D.; Ling, D.; Su, S-P; Nelson, C.; Chang, D. K.; Koach, J.; Tee, A. E.; Haber, M.; Norris, M. D.; Toon, C.; Rooman, I.; Xue, C.; Cheung, B. B.; Kumar, S.; Marshall, G. M.; Biankin, A. V.; Liu, T. Share Save
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The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro Cheung, Belamy B.; Koach, Jessica; Tan, Owen; Kim, Patrick; Bell, Jessica L.; D'andreti, Carla; Sutton, Selina; Malyukova, Alena; Sekyere, Eric; Norris, Murray; Haber, Michelle; Kavallaris, Maria; Cunningham, Anne M.; Proby, Charlotte; Leigh, Irene; Wilmott, James S.; Cooper, Caroline L.; Halliday, Gary M.; Scolyer, Richard A.; Marshall, Glenn M. Share Save
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