Not logged in Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx Crompton, Michael; Ferguson, Joanne K.; Ramnath, Raina D.; Onions, Karen L.; Ogier, Anna S.; Gamez, Monica; Down, Colin J.; Skinner, Laura; Wong, Kitty H.; Dixon, Lauren K.; Sutak, Judit; Harper, Steven J.; Pontrelli, Paola; Gesualdo, Loreto; Heerspink, Hiddo L.; Toto, Robert D.; Welsh, Gavin I.; Foster, Rebecca R.; Satchell, Simon C.; Butler, Matthew J. Share Save
NRF2 activation by reversible KEAP1 binding induces the antioxidant response in primary neurons and astrocytes of a Huntington's disease mouse model Moretti, Daniele; Tambone, Sara; Cerretani, Mauro; Fezzardi, Paola; Missineo, Antonino; Sherman, Leticia-Toledo; Munoz-Sajuan, Ignacio; Harper, Steven; Dominquez, Celia; Pacifici, Robert; Tomei, Licia; Park, Larry; Bresciani, Alberto Share Save
Cyclic Phosphopantothenic Acid Prodrugs for Treatment of Pantothenate Kinase-Associated Neurodegeneration Auciello, Giulio; Di Marco, Annalise; Paz, Odalys Gonzalez; Malancona, Savina; Harper, Steven; Beconi, Maria; Rossetti, Ilaria; Ciammaichella, Alina; Fezzardi, Paola; Vecchi, Andrea; Bracacel, Elena; Cicero, Daniel; Monteagudo, Edith; Elbaum, Daniel Share Save
Spiro-containing derivatives show antiparasitic activity against Trypanosoma brucei through inhibition of the trypanothione reductase enzyme Turcano, Lorenzo; Battista, Theo; De Haro, Esther Torrente; Missineo, Antonino; Alli, Cristina; Paonessa, Giacomo; Colotti, Gianni; Harper, Steven; Fiorillo, Annarita; Ilari, Andrea; Bresciani, Alberto Share Save
Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction Ontoria, Jesus M.; Biancofiore, Ilaria; Fezzardi, Paola; Ferrigno, Federica; Torrente, Esther; Colarusso, Stefania; Bianchi, Elisabetta; Andreini, Matteo; Patsilinakos, Alexandros; Kempf, Georg; Augustin, Martin; Steinbacher, Stefan; Summa, Vincenzo; Pacifici, Robert; Munoz-Sanjuan, Ignacio; Park, Larry; Bresciani, Alberto; Dominguez, Celia; Sherman, Leticia Toledo; Harper, Steven Share Save
Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors Perpetuini, Andrea Cerquone; Giuliani, Giulio; Reggio, Alessio; Cerretani, Mauro; Santoriello, Marisabella; Stefanelli, Roberta; Palma, Alessandro; Vumbaca, Simone; Harper, Steven; Castagnoli, Luisa; Bresciani, Alberto; Cesareni, Gianni Share Save
5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein Malancona, Savina; Mori, Mattia; Fezzardi, Paola; Santoriello, Marisabella; Basta, Andreina; Nibbio, Martina; Kovalenko, Lesia; Speziale, Roberto; Battista, Maria Rosaria; Cellucci, Antonella; Gennari, Nadia; Monteagudo, Edith; Di Marco, Annalise; Giannini, Alessia; Sharma, Rajhans; Pires, Manuel; Real, Eleonore; Zazzi, Maurizio; Lang, Maria Chiara Dasso; De Forni, Davide; Saladini, Francesco; Mely, Yves; Summa, Vincenzo; Harper, Steven; Botta, Maurizio Share Save
Share Save
Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides Bresciani, Alberto; Ontoria, Jesus M.; Biancofiore, Ilaria; Cellucci, Antonella; Ciammaichella, Alina; Di Marco, Annalise; Ferrigno, Federica; Francone, Alessandra; Malancona, Savina; Monteagudo, Edith; Nizi, Emanuela; Pace, Paola; Ponzi, Simona; Rossetti, Ilaria; Veneziano, Maria; Summa, Vincenzo; Harper, Steven Share Save
Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening Turcano, Lorenzo; Torrente, Esther; Missineo, Antonino; Andreini, Matteo; Gramiccia, Marina; Di Muccio, Trentina; Genovese, Ilaria; Fiorillo, Annarita; Harper, Steven; Bresciani, Alberto; Colotti, Gianni; Ilari, Andrea Share Save
Share Save
Physiological Role of Vascular Endothelial Growth Factors as Homeostatic Regulators Bates, David O.; Beazley-Long, Nicholas; Benest, Andrew V.; Ye, Xi; Ved, Nikita; Hulse, Richard P.; Barratt, Shaney; Machado, Maria J.; Donaldson, Lucy F.; Harper, Steven J.; Peiris-Pages, Maria; Tortonese, Domingo J.; Oltean, Sebastian; Foster, Rebecca R. Share Save
Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains Mori, Mattia; Kovalenko, Lesia; Malancona, Savina; Saladini, Francesco; De Forni, Davide; Pires, Manuel; Humbert, Nicolas; Real, Eleonore; Botzanowski, Thomas; Cianferani, Sarah; Giannini, Alessia; Dasso Lang, Maria Chiara; Cugia, Giulia; Poddesu, Barbara; Lori, Franco; Zazzi, Maurizio; Harper, Steven; Summa, Vincenzo; Mely, Yves; Botta, Maurizio Share Save
Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production Guidi, Alessandra; Lalli, Cristiana; Gimmelli, Roberto; Nizi, Emanuela; Andreini, Matteo; Gennari, Nadia; Saccoccia, Fulvio; Harper, Steven; Bresciani, Alberto; Ruberti, Giovina Share Save
Nuclear factor (erythroid-derived 2)-like 2 (NRF2) drug discovery: Biochemical toolbox to develop NRF2 activators by reversible binding of Kelch-like ECH-associated protein 1 (KEAP1) Bresciani, Alberto; Missineo, Antonino; Gallo, Mariana; Cerretani, Mauro; Fezzardi, Paola; Tomei, Licia; Cicero, Daniel Oscar; Altamura, Sergio; Santoprete, Alessia; Ingenito, Raffaele; Bianchi, Elisabetta; Pacifici, Robert; Dominguez, Celia; Munoz-Sanjuan, Ignacio; Harper, Steven; Toledo-Sherman, Leticia; Park, Larry C. Share Save
Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs Ontoria, Jesus M.; Paonessa, Giacomo; Ponzi, Simona; Ferrigno, Federica; Nizi, Emanuela; Biancofiore, Ilaria; Malancona, Savina; Graziani, Rita; Roberts, David; Willis, Paul; Bresciani, Alberto; Gennari, Nadia; Cecchetti, Ottavia; Monteagudo, Edith; Orsale, Maria V.; Veneziano, Maria; Di Marco, Annalise; Cellucci, Antonella; Laufer, Ralph; Altamura, Sergio; Summa, Vincenzo; Harper, Steven Share Save
P2-Quinazolinones and Bis-Macrocycles as New Templates for Next-Generation Hepatitis C Virus NS3/4a Protease Inhibitors: Discovery of MK-2748 and MK-6325 Rudd, Michael T.; Butcher, John W.; Nguyen, Kevin T.; McIntyre, Charles J.; Romano, Joseph J.; Gilbert, Kevin F.; Bush, Kimberly J.; Liverton, Nigel J.; Holloway, M. Katharine; Harper, Steven; Ferrara, Marco; DiFilippo, Marcello; Summa, Vincenzo; Swestock, John; Fritzen, Jeff; Carroll, Steven S.; Burlein, Christine; DiMuzio, Jillian M.; Gates, Adam; Graham, Donald J.; Huang, Qian; McClain, Stephanie; McHale, Carolyn; Stahlhut, Mark W.; Black, Stuart; Chase, Robert; Soriano, Aileen; Fandozzi, Christine M.; Taylor, Anne; Trainor, Nicole; Olsen, David B.; Coleman, Paul J.; Ludmerer, Steven W.; McCauley, John A. Share Save
Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia Hulse, R. P.; Beazley-Long, N.; Hua, J.; Kennedy, H.; Prager, J.; Bevan, H.; Qiu, Y.; Fernandes, E. S.; Gammons, M. V.; Ballmer-Hofer, K.; de Groot, A. C. Gittenberger; Churchill, A. J.; Harper, S. J.; Brain, S. D.; Bates, D. O.; Donaldson, L. F. Share Save
Share Save
MK-5172, a Selective Inhibitor of Hepatitis C Virus NS3/4a Protease with Broad Activity across Genotypes and Resistant Variants (vol 56, pg 4161, 2012) Summa, Vincenzo; Ludmerer, Steven W.; McCauley, John A.; Fandozzi, Christine; Burlein, Christine; Claudio, Giuliano; Coleman, Paul J.; DiMuzio, Jillian M.; Ferrara, Marco; Di Filippo, Marcello; Gates, Adam T.; Graham, Donald J.; Harper, Steven; Hazuda, Daria J.; Huang, Qian; McHale, Carolyn; Monteagudo, Edith; Pucci, Vincenzo; Rowley, Michael; Rudd, Michael T.; Soriano, Aileen; Stahlhut, Mark W.; Vacca, Joseph P.; Olsen, David B.; Liverton, Nigel J.; Carroll, Steven S. Share Save
.png){kind=icon}
.png){kind=icon}
Not logged in.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
