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Urinary Kidney Injury Biomarker Profiles in Healthy Individuals and After Nephrotoxic and Ischemic Injury Waikar, Sushrut S.; Mogg, Robin; Baker, Amanda F.; Frendl, Gyorgy; Topper, Michael; Adler, Scott; Sultana, Stefan; Zhao, Runqi; King, Nicholas M. P.; Piccoli, Steven P.; Sauer, John-Michael; Hoffmann, Steve; Nunes, Irene; Sistare, Frank D. Share Save
Lethal COVID-19 associates with RAAS- induced inflammation for multiple organ damage including mediastinal lymph nodes Topper, Michael J.; Guarnieri, Joseph W.; Haltom, Jeffrey A.; Chadburn, Amy; Cope, Henry; Frere, Justin; An, Julia; Borczuk, Alain; Sinha, Saloni; Kim, Jangkeun; Park, Jiwoon; Butler, Daniel; Meydan, Cem; Foox, Jonathan; Bram, Yaron; Richard, Stephanie A.; Epsi, Nusrat J.; Agan, Brian; Chenoweth, Josh G.; Simons, Mark P.; Tribble, David; Burgess, Timothy; Dalgard, Clifton; Heise, Mark T.; Moorman, Nathaniel J.; Baxter, Victoria K.; Madden, Emily A.; Taft-Benz, Sharon A.; Anderson, Elizabeth J.; Sanders, Wes A.; Dickmander, Rebekah J.; Beigel, Katherine; Widjaja, Gabrielle A.; Janssen, Kevin A.; Lie, Timothy; Murdock, Deborah G.; Angelin, Alessia; Albrecht, Yentli E. Soto; Olali, Arnold Z.; Cen, Zimu; Dybas, Joseph; Priebe, Waldemar; Emmett, Mark R.; Best, Sonja M.; Johnson, Maya Kelsey; Trovao, Nidia S.; Clark, Kevin B.; Zaksas, Victoria; Meller, Robert; Grabham, Peter; Schisler, Jonathan C.; Moraes-Vieira, Pedro M.; Pollett, Simon; Mason, Christopher E.; Wurtele, Eve Syrkin; Taylor, Deanne; Schwartz, Robert E.; Beheshti, Afshin; Wallace, Douglas C.; Baylin, Stephen B. Share Save
Space radiation damage rescued by inhibition of key spaceflight associated miRNAs McDonald, J. Tyson; Kim, JangKeun; Farmerie, Lily; Johnson, Meghan L.; Trovao, Nidia S.; Arif, Shehbeel; Siew, Keith; Tsoy, Sergey; Bram, Yaron; Park, Jiwoon; Overbey, Eliah; Ryon, Krista; Haltom, Jeffrey; Singh, Urminder; Enguita, Francisco J.; Zaksas, Victoria; Guarnieri, Joseph W.; Topper, Michael; Wallace, Douglas C.; Meydan, Cem; Baylin, Stephen; Meller, Robert; Muratani, Masafumi; Porterfield, D. Marshall; Kaufman, Brett; Mori, Marcelo A.; Walsh, Stephen B.; Sigaudo-Roussel, Dominique; Mebarek, Saida; Bottini, Massimo; Marquette, Christophe A.; Wurtele, Eve Syrkin; Schwartz, Robert E.; Galeano, Diego; Mason, Christopher E.; Grabham, Peter; Beheshti, Afshin Share Save
Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling Chomiak, Alison A.; Tiedemann, Rochelle L.; Liu, Yanqing; Kong, Xiangqian; Cui, Ying; Wiseman, Ashley K.; Thurlow, Kate E.; Cornett, Evan M.; Topper, Michael J.; Baylin, Stephen B.; Rothbart, Scott B. Share Save
ZNFX1 is a master regulator and tumor suppressor in epigenetically induced pathogen mimicry, mitochondrial dysfunction and STING-dependent signaling in cancer Stojanovic, Lora; Abbotts, Rachel; Tripathi, Kaushlendra; Coon, Collin M.; Liu, Sheng; Wan, Jun; Topper, Michael; Baylin, Stephen; Nephew, Kenneth; Rassool, Feyruz Share Save
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Comprehensive genomic and transcriptomic analyses capture the effects of epigenetic therapy priming on immune checkpoint blockade response in non-small cell lung cancer Landon, Blair V.; Marrone, Kristen A.; Topper, Michael J.; Annapragada, Akshaya; Tsai, Hua-Ling; Balan, Archana; Niknafs, Noushin; Cherry, Christopher; White, James R.; Pereira, Gavin; Adleff, Vilmos; Hu, Chen; Riemer, Joanne; Fitzpatrick, Margaret; Forde, Patrick; Hann, Christine L.; Kelly, Ronan J.; Ettinger, David S.; Levy, Benjamin; Nieva, Jorge; Herman, James; Velculescu, Victor E.; Baylin, Stephen; Brahmer, Julie; Anagnostou, Valsamo Share Save
ZNFX1 is a master regulator for epigenetic reprograming of mitochondrial inflammasome signaling and pathogen mimicry in cancer cells Stojanovic, Lora; Abbotts, Rachel; Tripathi, Kaushlendra; Coon, Collin M.; Liu, Sheng; Wan, Jun; Topper, Michael J.; Nephew, Kenneth P.; Baylin, Stephen B.; Rassool, Feyruz V. Share Save
A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infection Narayanan, S. Anand; Jamison, David A., Jr.; Guarnieri, Joseph W.; Zaksas, Victoria; Topper, Michael; Koutnik, Andrew P.; Park, Jiwoon; Clark, Kevin B.; Enguita, Francisco J.; Leitao, Ana Lucia; Das, Saswati; Moraes-Vieira, Pedro M.; Galeano, Diego; Mason, Christopher E.; Trovao, Nidia S.; Schwartz, Robert E.; Schisler, Jonathan C.; Coelho-dos-Reis, Jordana G. A.; Wurtele, Eve Syrkin; Beheshti, Afshin Share Save
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Activating STING1-dependent immune signaling in TP53 mutant and wild-type acute myeloid leukemia Kogan, Aksinija A.; Topper, Michael J.; Dellomo, Anna J.; Stojanovic, Lora; McLaughlin, Lena J.; Creed, T. Michael; Eberly, Christian L.; Kingsbury, Tami J.; Baer, Maria R.; Kessler, Michael D.; Baylin, Stephen B.; Rassool, Feyruz, V Share Save
A comprehensive SARS-CoV-2 and COVID-19 review, Part 1: Intracellular overdrive for SARS-CoV-2 infection Jamison, David A.; Narayanan, S. Anand; Trovao, Nidia S.; Guarnieri, Joseph W.; Topper, Michael J.; Moraes-Vieira, Pedro M.; Zaksas, Viktorija; Singh, Keshav K.; Wurtele, Eve Syrkin; Beheshti, Afshin Share Save
Evaluating the impact of age on immune checkpoint therapy biomarkers (vol 36, 109599, 2021) Erbe, Rossin; Wang, Zheyu; Wu, Sharon; Xiu, Joanne; Zaidi, Neeha; La, Jennifer; Tuck, David; Fillmore, Nathanael; Giraldo, Nicolas A.; Topper, Michael; Baylin, Stephen; Lippman, Marc; Isaacs, Claudine; Basho, Reva; Serebriiskii, Ilya; Lenz, Heinz-Josef; Astsaturov, Igor; Marshall, John; Taverna, Josephine; Lee, Jerry; Jaffee, Elizabeth M.; Torres, Evanthia T. Roussos; Weeraratna, Ashani; Easwaran, Hariharan; Fertig, Elana J. Share Save
Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner McDonald, James, I; Diab, Noor; Arthofer, Elisa; Hadley, Melissa; Kanholm, Tomas; Rentia, Uzma; Gomez, Stephanie; Yu, Angela; Grundy, Erin E.; Cox, Olivia; Topper, Michael J.; Xing, Xiaoyun; Strissel, Pamela L.; Strick, Reiner; Wang, Ting; Baylin, Stephen B.; Chiappinelli, Katherine B. Share Save
Evaluating the impact of age on immune checkpoint therapy biomarkers Erbe, Rossin; Wang, Zheyu; Wu, Sharon; Xiu, Joanne; Zaidi, Neeha; La, Jennifer; Tuck, David; Fillmore, Nathanael; Giraldo, Nicolas A.; Topper, Michael; Baylin, Stephen; Lippman, Marc; Isaacs, Claudine; Basho, Reva; Serebriiskii, Ilya; Lenz, Heinz-Josef; Astsaturov, Igor; Marshall, John; Taverna, Josephine; Lee, Jerry; Jaffee, Elizabeth M.; Torres, Evanthia T. Roussos; Weeraratna, Ashani; Easwaran, Hariharan; Fertig, Elana J. Share Save
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Pharmacologic induction of innate immune signaling directly drives homologous recombination deficiency McLaughlin, Lena J.; Stojanovic, Lora; Kogan, Aksinija A.; Rutherford, Julia L.; Choi, Eun Yong; Yen, Ray-Whay Chiu; Xia, Limin; Zou, Ying; Lapidus, Rena G.; Baylin, Stephen B.; Topper, Michael J.; Rassool, Feyruz V. Share Save
DNA methyltransferase inhibitors induce a BRCAness phenotype that sensitizes NSCLC to PARP inhibitor and ionizing radiation Abbotts, Rachel; Topper, Michael J.; Biondi, Christopher; Fontaine, Daniel; Goswami, Reena; Stojanovic, Lora; Choi, Eun Yong; McLaughlin, Lena; Kogan, Aksinija A.; Xia, Limin; Lapidus, Rena; Mahmood, Javed; Baylin, Stephen B.; Rassool, Feyruz V. Share Save
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