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Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer Dilly, Julien; Hoffman, Megan T.; Abbassi, Laleh; Li, Ziyue; Paradiso, Francesca; Parent, Brendan D.; Hennessey, Connor J.; Jordan, Alexander C.; Morgado, Micaela; Dasgupta, Shatavisha; Uribe, Giselle A.; Yang, Annan; Kapner, Kevin S.; Hambitzer, Felix P.; Qiang, Li; Feng, Hanrong; Geisberg, Jacob; Wang, Junning; Evans, Kyle E.; Lyu, Hengyu; Schalck, Aislyn; Feng, Ningping; Lopez, Anastasia M.; Bristow, Christopher A.; Kim, Michael P.; Rajapakshe, Kimal I.; Bahrambeigi, Vahid; Roth, Jennifer A.; Garg, Kavita; Guerrero, Paola A.; Stanger, Ben Z.; Cristea, Simona; Lowe, Scott W.; Baslan, Timour; Van Allen, Eliezer M.; Mancias, Joseph D.; Chan, Emily; Anderson, Abraham; Katlinskaya, Yuliya V.; Shalek, Alex K.; Hong, David S.; Pant, Shubham; Hallin, Jill; Anderes, Kenna; Olson, Peter; Heffernan, Timothy P.; Chugh, Seema; Christensen, James G.; Maitra, Anirban; Wolpin, Brian M.; Raghavan, Srivatsan; Nowak, Jonathan A.; Winter, Peter S.; Dougan, Stephanie K.; Aguirre, Andrew J. Share Save
Dissecting and quantifying pancreatic cancer plasticity using single-cell multiomics, lineage tracing and functional genomics reveals novel mediators of therapy resistance Mehta, Arnav; Bi, Lynn; Yeramosu, Deepika; Bogaev, Michael; Jankowiak, Martin; Collins, Abigail; Al'Khafaji, Aziz; Parikh, Milan; Babadi, Mehrtash; Evans, Kyle; Bloemendal, Alex; Kunnes, Russell; Schwartz, Marc; Munson, Glen; Donnard, Elisa; Jones, Thouis R.; Stanger, Ben Z.; Shendure, Jay; Weissman, Jonathan; Ting, David T.; Aguirre, Andrew; Hacohen, Nir; Pe'er, Dana; Lander, Eric S. Share Save
KDM4C histone demethylase connects redox balance to chromatin remodeling via histone H3 tail clipping Li, Zheqi; Peluffo, Guillermo; Stevens, Laura; Qiu, Xintao; Seehawer, Marco; Huang, Xiao-Yun; Egri, Shawn; Papanastasiou, Malvina; Kingston, Natalie; D'Santos, Clive; Papachristou, Eva; Nishida, Jun; Evans, Kyle; Seo, Ji-Heui; Clement, Kendell; Temko, Daniel; Ekram, Muhammad; Rees, Matthew; Ronan, Melissa; Roth, Jennifer; Simeonov, Anton; Kales, Stephen; Rai, Ganesha; Lal-Nag, Madhu; Maloney, David; Jadhav, Ajit; Michor, Franziska; Meissner, Alex; Balko, Justin; Carroll, Jason; Freedman, Matthew; Long, Henry; Jaffe, Jacob; Polyak, Kornelia Share Save
Causal inference in medical records and complementary systems pharmacology for metformin drug repurposing towards dementia Charpignon, Marie-Laure; Vakulenko-Lagun, Bella; Zheng, Bang; Magdamo, Colin; Su, Bowen; Evans, Kyle; Rodriguez, Steve; Sokolov, Artem; Boswell, Sarah; Sheu, Yi-Han; Somai, Melek; Middleton, Lefkos; Hyman, Bradley T.; Betensky, Rebecca A.; Finkelstein, Stan N.; Welsch, Roy E.; Tzoulaki, Ioanna; Blacker, Deborah; Das, Sudeshna; Albers, Mark W. Share Save
Genome-encoded cytoplasmic double-stranded RNAs, found in C9ORF72 ALS-FTD brain, propagate neuronal loss Rodriguez, Steven; Sahin, Asli; Schrank, Benjamin R.; Al-Lawati, Hawra; Costantino, Isabel; Benz, Eric; Fard, Darian; Albers, Alefiya D.; Cao, Luxiang; Gomez, Alexis C.; Evans, Kyle; Ratti, Elena; Cudkowicz, Merit; Frosch, Matthew P.; Talkowski, Michael; Sorger, Peter K.; Hyman, Bradley T.; Albers, Mark W. Share Save
Machine learning identifies candidates for drug repurposing in Alzheimer's disease Rodriguez, Steve; Hug, Clemens; Todorov, Petar; Moret, Nienke; Boswell, Sarah A.; Evans, Kyle; Zhou, George; Johnson, Nathan T.; Hyman, Bradley T.; Sorger, Peter K.; Albers, Mark W.; Sokolov, Artem Share Save
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