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William R. Bishai

weill cornell medicine

87H-index
463Paper Count
2.5WCitation Count
Published Papers 208
Publication Date
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Host-directed treatments for tuberculous meningitis utilizing a multi-platform approach across mouse and human models
errNature Communications
IF15.7
err2026-07-21
err0
errOAAI
errCarlos E. Ruiz-Gonzalez; Medha Singh; Yuderleys Masias-Leon; Xueyi Chen; Mona O. Sarhan; Yazmin B. Martinez-Martinez; Sruti Patel; Madelynn Shambles; Andres Villabona-Rueda; Kadia Lissit; David Tweedie; Michael T. Scerba; William R. Bishai; Dmitri Artemov; Jin-Chong Xu; Franco D’Alessio; Richard Hafner; Nigel H. Greig; Maura Manion; Irini Sereti; Sanjay K. Jain
errShare
errSave
Elimination of senescent cells with senolytic drugs as adjunctive host-directed therapy reduces tuberculosis progression in mice
errNature Communications
IF15.7
err2026-05-07
err0
errOAAI
errSomnath Shee; Yazmin B. Martinez-Martinez; Benjamin Koleske; Moagi Tube Shaku; Shivraj Yabaji; Lester Kobzik; Igor Kramnik; William Bishai
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errSave
Retraction Note: Re-engineered BCG overexpressing cyclic di-AMP augments trained immunity and exhibits improved efficacy against bladder cancer
errNature Communications
IF15.7
err2026-03-23
err0
errOAAI
errAlok Kumar Singh; Monali Praharaj; Kara A. Lombardo; Takahiro Yoshida; Andres Matoso; Alex S. Baras; Liang Zhao; Geetha Srikrishna; Joy Huang; Pankaj Prasad; Jonathan D. Powell; Max Kates; David McConkey; Drew M. Pardoll; William R. Bishai; Trinity J. Bivalacqua
errShare
errSave
Sex as a Biological Variable in Tuberculosis Pathogenesis
errImmunological Reviews
IF8.3
err2026-03-10
err0
PREAI
errManish Gupta; Sabra L. Klein; William R. Bishai
errShare
errSave
Molecular characterization of non-muscle invasive tumor from N-methyl-N-nitrosourea (MNU)-induced urothelial carcinoma in a rat model reveals hallmarks of both luminal and basal subtypes
errExperimental and Molecular Pathology
IF3.7
err2026-02-09
err0
errOAAI
errKara A. Lombardo; Takahiro Yoshida; Evan Johnson; Kate Fitzgerald; Max Kates; William R. Bishai; Alex S. Baras; Trinity J. Bivalacqua
errShare
errSave
A novel glutamine metabolism inhibitor improves phagocytic abilities of macrophages by reprogramming glutathione metabolism
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errNesson, Sadiya Parveen; Murphy, John R.; Slusher, Barbara L.; Bishai, William R.
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errSave
Exploration of imidazothiazole and imidazopyrimidine carboxamides for enhanced antitubercular activity
errBioorganic & Medicinal Chemistry Letters
IF2.2
err2025-10-21
err0
PREAI
errOluseye K. Onajole; Shichun Lun; Dakoju Ravi Kishore; Anđela Savić; Alexis Morales; Alfredo Guzman; Ethan Schmidt; Adela Lazzara; Gianna Fajardo; Daniel P. Jamieson; A. Jean-Luc Ayitou; William R. Bishai
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errSave
Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility
errELIFE
IF0
err2025-10-02
err0
PREAI
errYabaji, Shivraj M.; Zhernovkov, Vadim; Araveti, Prasanna Babu; Lata, Suruchi; Rukhlenko, Oleksii S.; Abdullatif, Salam Al; Vanvalkenburg, Arthur; Alekseyev, Yuriy O.; Ma, Qicheng; Dayama, Gargi; Lau, Nelson C.; Johnson, W. Evan; Bishai, William R.; Crossland, Nicholas A.; Campbell, Joshua D.; Kholodenko, Boris N.; Gimelbrant, Alexander A.; Kobzik, Lester; Kramnik, Igor
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errSave
Dysplastic lung repair fosters a tuberculosis-promoting microenvironment through maladaptive macrophage polarization
errPLOS PATHOGENS
IF4.9
err2025-10-01
err0
PREAI
errYabaji, Shivraj M.; Lata, Suruchi; Tseng, Anna E.; Araveti, Prasanna Babu; Lo, Ming; Gavrish, Igor; O'Connell, Aoife K.; Gertje, Hans P.; Belkina, Anna C.; Thurman, Colleen E.; Kiyokawa, Hirofumi; Kotton, Darrell; Tan, Shumin; Endsley, Janice J.; Bishai, William R.; Crossland, Nicholas; Kobzik, Lester; Kramnik, Igor
errShare
errSave
Loss of the PPE71-esxX-esxY-PPE38 locus drives adaptive transcriptional responses and hypervirulence of Mycobacterium tuberculosis lineage 2
errScience Advances
IF12.5
err2025-07-04
err0
PREAI
errBenjamin Koleske; Courtney Schill; Saranathan Rajagopalan; Somnath Shee; Yazmin B. Martinez-Martinez; Manish Gupta; Jessica Shen; William R. Jacobs; William R. Bishai
errShare
errSave
Structure-Based Development of 3,4-Fused Tricyclic Benzofuran Derivatives as Polyketide Synthase 13 Inhibitors with Negligible hERG Inhibition
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-03-06
err0
PREAI
errZhou, Yu-Xin; Lun, Shichun; Zhang, Wei; Tie, Fa-Jin; Cai, Yan-Peng; Yang, Fan; Tang, Jie; Bishai, William R.; Yu, Li-Fang
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errSave
Structure-based development of N-Arylindole derivatives as Pks13 inhibitors against Mycobacterium tuberculosis (vol 283, 117148, 2025)
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-03-01
err0
PREAI
errZhang, Xuan; Lun, Shichun; Li, Yu-Xin; Zhang, Wei; Zhou, Ruo-Yi; Liu, Ting; Yang, Fan; Tang, Jie; Bishai, William R.; Yu, Li-Fang
errShare
errSave
Structure-based development of N-Arylindole derivatives as Pks13 inhibitors against Mycobacterium tuberculosis
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-02-01
err1
PREAI
errZhang, Xuan; Lun, Shichun; Li, Yu-Xin; Zhang, Wei; Zhou, Ruo-Yi; Liu, Ting; Yang, Fan; Tang, Jie; Bishai, William R.; Yu, Li-Fang
errShare
errSave
Total Syntheses of Cyclomarin and Metamarin Natural Products
errORGANIC LETTERS
IF5
err2024-11-01
err0
errOAAI
errFei, Fan; Lun, Shichun; Saxena, Aditi; Raghavan, Madhura; Derisi, Joseph L.; Bishai, William R.; Sello, Jason K.
errShare
errSave
Pathogenesis of Post-Tuberculosis Lung Disease
errAMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
err2024-10-15
err0
PREAI
errAuld, Sara C.; Barczak, Amy K.; Bishai, William; Coussens, Anna K.; Dewi, Intan M. W.; Mitini-Nkhoma, Steven C.; Muefong, Caleb; Naidoo, Threnesan; Pooran, Anil; Stek, Cari; Steyn, Adrie J. C.; Tezera, Liku; Walker, Naomi F.
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errSave
A modified BCG with depletion of enzymes associated with peptidoglycan amidation induces enhanced protection against tuberculosis in mice
errELIFE
IF0
err2024-04-19
err1
errOAAI
errShaku, Moagi Tube; Um, Peter K.; Ocius, Karl L.; Apostolos, Alexis J.; Pires, Marcos M.; Bishai, William R.; Kana, Bavesh D.
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errSave
Design, synthesis, and biological evaluation of 1,2,4-triazole derivatives as potent antitubercular agents
errCHINESE CHEMICAL LETTERS
IF8.9
err2024-03-01
err7
PREAI
errWen, Yu; Lun, Shichun; Jiao, Yuxue; Zhang, Wei; Hu, Tianyu; Liu, Ting; Yang, Fan; Tang, Jie; Zhang, Bing; Bishai, William R.; Yu, Li-Fang
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errSave
Structure-based virtual screening and in vitro validation of inhibitors of cyclic dinucleotide phosphodiesterases ENPP1 and CdnP
errMICROBIOLOGY SPECTRUM
IF3.8
err2024-01-11
err1
errOAAI
errRohilla, Akshay; Singh, Alok Kumar; Koleske, Benjamin; Srikrishna, Geetha; Bishai, William R.
errShare
errSave
Inhibition of host PARP1 contributes to the anti-inflammatory and antitubercular activity of pyrazinamide
errNATURE COMMUNICATIONS
IF15.7
err2023-12-09
err5
errOAAI
errKrug, Stefanie; Gupta, Manish; Kumar, Pankaj; Feller, Laine; Ihms, Elizabeth A.; Kang, Bong Gu; Srikrishna, Geetha; Dawson, Ted M.; Dawson, Valina L.; Bishai, William R.
errShare
errSave
MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival
errJCI INSIGHT
IF6.1
err2023-10-23
err8
errOAAI
errBullen, C. Korin; Singh, Alok K.; Krug, Stefanie; Lun, Shichun; Thakur, Preeti; Srikrishna, Geetha; Bishai, William R.
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errSave

Research Directions

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Co-authors
Cooperation Journals
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Drew M. Pardoll
H-index: 164 · Papers: 892
V
Valina L. Dawson
H-index: 151 · Papers: 579
C
Charles G. Drake
H-index: 133 · Papers: 1.2K
A
Alan Sher
H-index: 133 · Papers: 555
L
Laurent Abel
H-index: 131 · Papers: 659
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