Philippe Sanséau - Publications, H-index & Citations

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Philippe Sanséau

GSK

28H-index

98Paper Count

1.3WCitation Count

Published Papers 29

Publication Date

Evaluating transportability of in vitro cellular models to in vivo human phenotypes using gene perturbation data

Nature Communications

IF15.7

2025-12-13

OAAI

Laurence J. Howe; Yurii S. Aulchenko; George Davey Smith; Neil M. Davies; Jorge Esparza-Gordillo; Toby Johnson; Jimmy Z. Liu; Tom G. Richardson; Philippe Sanseau; Robert A. Scott; Daniel D. Seaton; Ashwini Sharma; Adrian Cortes

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Interleukin-18 as a drug repositioning opportunity for inflammatory bowel disease: A Mendelian randomization study

SCIENTIFIC REPORTS

IF3.9

2019-06-28

OAAI

Mokry, Lauren E.; Zhou, Sirui; Guo, Cong; Scott, Robert A.; Devey, Luke; Langenberg, Claudia; Wareham, Nick; Waterworth, Dawn; Cardon, Lon; Sanseau, Philippe; Smith, George Davey; Richards, J. Brent

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Drug repurposing: progress, challenges and recommendations

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2018-10-12

2.8K

PREAI

Pushpakom, Sudeep; Iorio, Francesco; Eyers, Patrick A.; Escott, K. Jane; Hopper, Shirley; Wells, Andrew; Doig, Andrew; Guilliams, Tim; Latimer, Joanna; McNamee, Christine; Norris, Alan; Sanseau, Philippe; Cavalla, David; Pirmohamed, Munir

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Uncovering novel repositioning opportunities using the Open Targets platform

DRUG DISCOVERY TODAY

IF7.5

2017-12-01

PREAI

Khaladkar, Mugdha; Koscielny', Gautier; Hasan, Samiul; Agarwal, Pankaj; Dunham, Ian; Rajpal, Deepak; Sanseau, Philippe

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In silico prediction of novel therapeutic targets using gene-disease association data

JOURNAL OF TRANSLATIONAL MEDICINE

IF7.5

2017-08-29

OAAI

Ferrero, Enrico; Dunham, Ian; Sanseau, Philippe

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Harnessing public domain data to discover and validate therapeutic targets

EXPERT OPINION ON DRUG DISCOVERY

IF4.9

2017-05-23

PREAI

Reisdorf, William C.; Chhugani, Neha; Sanseau, Philippe; Agarwal, Pankaj

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Open Targets: a platform for therapeutic target identification and validation

NUCLEIC ACIDS RESEARCH

IF13.1

2016-11-29

298

OAAI

Koscielny, Gautier; An, Peter; Carvalho-Silva, Denise; Cham, Jennifer A.; Fumis, Luca; Gasparyan, Rippa; Hasan, Samiul; Karamanis, Nikiforos; Maguire, Michael; Papa, Eliseo; Pierleoni, Andrea; Pignatelli, Miguel; Platt, Theo; Rowland, Francis; Wankar, Priyanka; Bento, A. Patricia; Burdett, Tony; Fabregat, Antonio; Forbes, Simon; Gaulton, Anna; Gonzalez, Cristina Yenyxe; Hermjakob, Henning; Hersey, Anne; Jupe, Steven; Kafkas, Senay; Keays, Maria; Leroy, Catherine; Lopez, Francisco-Javier; Magarinos, Maria Paula; Malone, James; McEntyre, Johanna; Fuentes, Alfonso Munoz-Pomer; O'Donovan, Claire; Papatheodorou, Irene; Parkinson, Helen; Palka, Barbara; Paschall, Justin; Petryszak, Robert; Pratanwanich, Naruemon; Sarntivijal, Sirarat; Saunders, Gary; Sidiropoulos, Konstantinos; Smith, Thomas; Sondka, Zbyslaw; Stegle, Oliver; Tang, Amy; Turner, Edward; Vaughan, Brendan; Vrousgou, Olga; Watkins, Xavier; Martin, Maria-Jesus; Sanseau, Philippe; Vamathevan, Jessica; Birney, Ewan; Barrett, Jeffrey; Dunham, Ian

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Systematic Analysis of Drug Targets Confirms Expression in Disease-Relevant Tissues

SCIENTIFIC REPORTS

IF3.9

2016-11-08

OAAI

Kumar, Vinod; Sanseau, Philippe; Simola, Daniel F.; Hurle, Mark R.; Agarwal, Pankaj

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Higher mutation rate is associated with more frequent expression of cancer/testis antigens in human tumors

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Jing, Junping; Mayes, Patrick; Degenhardt, Yan; Brown, James R.; Sanseau, Philippe

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The support of human genetic evidence for approved drug indications

NATURE GENETICS

IF31.8

2015-06-29

996

PREAI

Nelson, Matthew R.; Tipney, Hannah; Painter, Jeffery L.; Shen, Judong; Nicoletti, Paola; Shen, Yufeng; Floratos, Aris; Sham, Pak Chung; Li, Mulin Jun; Wang, Junwen; Cardon, Lon R.; Whittaker, John C.; Sanseau, Philippe

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Systematic prediction of drug combinations based on clinical side-effects

SCIENTIFIC REPORTS

IF3.9

2014-11-24

OAAI

Huang, Hui; Zhang, Ping; Qu, Xiaoyan A.; Sanseau, Philippe; Yang, Lun

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Integrative clinical transcriptomics analyses for new therapeutic intervention strategies: a psoriasis case study

DRUG DISCOVERY TODAY

IF7.5

2014-09-01

PREAI

Qu, Xiaoyan A.; Freudenberg, Johannes M.; Sanseau, Philippe; Rajpal, Deepak K.

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Rational drug repositioning by medical genetics Reply

NATURE BIOTECHNOLOGY

IF41.7

2013-12-01

OAAI

Sanseau, Philippe; Agarwal, Pankaj; Barnes, Michael R.; Pastinen, Tomi; Richards, J. Brent; Cardon, Lon R.; Mooser, Vincent

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Novelty in the target landscape of the pharmaceutical industry

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2013-08-01

PREAI

Agarwal, Pankaj; Sanseau, Philippe; Cardon, Lon R.

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Minipig and beagle animal model genomes aid species selection in pharmaceutical discovery and development

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2013-07-01

PREAI

Vamathevan, Jessica J.; Hall, Matthew D.; Hasan, Samiul; Woollard, Peter M.; Xu, Meng; Yang, Yulan; Li, Xin; Wang, Xiaoli; Kenny, Steve; Brown, James R.; Huxley-Jones, Julie; Lyon, Jon; Haselden, John; Min, Jiumeng; Sanseau, Philippe

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Computational Drug Repositioning: From Data to Therapeutics

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2013-01-15

300

PREAI

Hurle, M. R.; Yang, L.; Xie, Q.; Rajpal, D. K.; Sanseau, P.; Agarwal, P.

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Use of genome-wide association studies for drug repositioning

NATURE BIOTECHNOLOGY

IF41.7