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Liver lipopolysaccharide binding protein prevents hepatic inflammation in physiological and pathological non-obesogenic conditions Milbank, Edward; Diaz-Trelles, Ramon; Dragano, Nathalia; Latorre, Jessica; Mukthavaram, Rajesh; Mayneris-Perxachs, Jordi; Ortega, Francisco; Federici, Massimo; Burcelin, Remy; Karmali, Priya P.; Tachikawa, Kiyoshi; Chivukula, Pad; Lopez, Miguel; Fernandez-Real, Jose Manuel; Moreno-Navarrete, Jose Maria Share Save
Downregulation of hepatic lipopolysaccharide binding protein improves lipogenesis-induced liver lipid accumulation Latorre, Jessica; Diaz-Trelles, Ramon; Comas, Ferran; Gavalda-Navarro, Aleix; Milbank, Edward; Dragano, Nathalia; Moron-Ros, Samantha; Mukthavaram, Rajesh; Ortega, Francisco; Castells-Nobau, Anna; Oliveras-Canellas, Nuria; Ricart, Wifredo; Karmali, Priya P.; Tachikawa, Kiyoshi; Chivukula, Pad; Villarroya, Francesc; Lopez, Miguel; Giralt, Marta; Fernandez-Real, Jose Manuel; Moreno-Navarrete, Jose Maria Share Save
Downregulation of peripheral lipopolysaccharide binding protein impacts on perigonadal adipose tissue only in female mice Comas, Ferran; Diaz-Trelles, Ramon; Gavalda-Navarro, Aleix; Milbank, Edward; Dragano, Nathalia; Moron-Ros, Samantha; Mukthavaram, Rajesh; Latorre, Jessica; Ortega, Francisco; Arnoriaga-Rodriguez, Maria; Oliveras-Canellas, Nuria; Ricart, Wifredo; Karmali, Priya P.; Tachikawa, Kiyoshi; Chivukula, Pad; Villarroya, Francesc; Giralt, Marta; Lopez, Miguel; Fernandez-Real, Jose Manuel; Moreno-Navarrete, Jose Maria Share Save
Development of an mRNA replacement therapy for phenylketonuria Perez-Garcia, Carlos G.; Diaz-Trelles, Ramon; Vega, Jerel Boyd; Bao, Yanjie; Sablad, Marciano; Limphong, Patty; Chikamatsu, Simon; Yu, Hailong; Taylor, Wendy; Karmali, Priya P.; Tachikawa, Kiyoshi; Chivukula, Padmanabh Share Save
Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function Wolff, Gretchen; Sakurai, Minako; Mhamane, Amit; Troullinaki, Maria; Maida, Adriano; Deligiannis, Ioannis K.; Yin, Kelvin; Weber, Peter; Morgenstern, Jakob; Wieder, Annika; Kwon, Yun; Sekar, Revathi; Zeigerer, Anja; Roden, Michael; Blueher, Matthias; Volk, Nadine; Poth, Tanja; Hackert, Thilo; Wiedmann, Lena; Rigotti, Francesca De Angelis; Rodriguez-Vita, Juan; Fischer, Andreas; Mukthavaram, Rajesh; Limphong, Pattraranee; Tachikawa, Kiyoshi; Karmali, Priya; Payne, Joseph; Chivukula, Padmanabh; Ekim-Uestuenel, Bilgen; Martinez-Jimenez, Celia P.; Szendroedi, Julia; Nawroth, Peter; Herzig, Stephan Share Save
Synthesis and bioactivity of readily hydrolysable novel cationic lipids for potential lung delivery application of mRNAs Pei, Yihua; Bao, Yanjie; Sacchetti, Cristiano; Brady, Juthamart; Gillard, Kyra; Yu, Hailong; Roberts, Scott; Rajappan, Kumar; Tanis, Steven P.; Perez-Garcia, Carlos G.; Chivukula, Padmanabh; Karmali, Priya P. Share Save
Selective suppression of polyglutamine-expanded protein by lipid nanoparticle-delivered siRNA targeting CAG expansions in the mouse CNS Hirunagi, Tomoki; Sahashi, Kentaro; Tachikawa, Kiyoshi; Leu, Angel I.; Nguyen, Michelle; Mukthavaram, Rajesh; Karmali, Priya P.; Chivukula, Padmanabh; Tohnai, Genki; Iida, Madoka; Onodera, Kazunari; Ohyama, Manabu; Okada, Yohei; Okano, Hideyuki; Katsuno, Masahisa Share Save
A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice de Alwis, Ruklanthi; Gan, Esther S.; Chen, Shiwei; Leong, Yan Shan; Tan, Hwee Cheng; Zhang, Summer L.; Yau, Clement; Low, Jenny G. H.; Kalimuddin, Shirin; Matsuda, Daiki; Allen, Elizabeth C.; Hartman, Paula; Park, Kyoung-Joo Jenny; Alayyoubi, Maher; Bhaskaran, Hari; Dukanovic, Adrian; Bao, Yanjie; Clemente, Brenda; Vega, Jerel; Roberts, Scott; Gonzalez, Jose A.; Sablad, Marciano; Yelin, Rodrigo; Taylor, Wendy; Tachikawa, Kiyoshi; Parker, Suezanne; Karmali, Priya; Davis, Jared; Sullivan, Brian M.; Sullivan, Sean M.; Hughes, Steve G.; Chivukula, Pad; Ooi, Eng Eong Share Save
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CD8+ T cells mediate protection against Zika virus induced by an NS3-based vaccine Ngono, Annie Elong; Syed, Thasneem; Anh-Viet Nguyen; Regla-Nava, Jose Angel; Susantono, Mercylia; Spasova, Darina; Aguilar, Allison; West, Melissa; Sparks, Jessica; Gonzalez, Andrew; Branche, Emilie; DeHart, Jason L.; Vega, Jerel Boyd; Karmali, Priya Prakash; Chivukula, Padmanabh; Kamrud, Kurt; Aliahmad, Parinaz; Wang, Nathaniel; Shresta, Sujan Share Save
Property-Driven Design and Development of Lipids for Efficient Delivery of siRNA Rajappan, Kumar; Tanis, Steven P.; Mukthavaram, Rajesh; Roberts, Scott; Nguyen, Michelle; Tachikawa, Kiyoshi; Sagi, Amit; Sablad, Marciano; Limphong, Pattraranee; Leu, Angel; Yu, Hailong; Chivukula, Padmanabh; Payne, Joseph E.; Karmali, Priya Share Save
Lipid Nanoparticle Formulation Increases Efficiency of DNA-Vectored Vaccines/Immunoprophylaxis in Animals Including Transchromosomic Bovines Mucker, Eric M.; Karmali, Priya P.; Vega, Jerel; Kwilas, Steven A.; Wu, Hua; Joselyn, Matthew; Ballantyne, John; Sampey, Darryl; Mukthavaram, Rajesh; Sullivan, Eddie; Chivukula, Pad; Hooper, Jay W. Share Save
Anti-HFRS Human IgG Produced in Transchromosomic Bovines Has Potent Hantavirus Neutralizing Activity and Is Protective in Animal Models Perley, Casey C.; Brocato, Rebecca L.; Wu, Hua; Bausch, Christoph; Karmali, Priya P.; Vega, Jerel B.; Cohen, Melanie V.; Somerville, Brandon; Kwilas, Steven A.; Principe, Lucia M.; Shamblin, Joshua; Chivukula, Padmanabh; Sullivan, Eddie; Hooper, Jay W. Share Save
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth Huang, Xinqiang; Magnus, Jill; Kaimal, Vivek; Karmali, Priya; Li, Jian; Walls, Marlena; Prudente, Rene; Sung, Eric; Sorourian, Mehran; Lee, Robin; Davis, Scott; Yang, Xia; Estrella, Heather; Lee, Edmund C.; Chau, B. Nelson; Pavlicek, Adam; Zabludoff, Sonya Share Save
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Therapeutic potential of targeting microRNA-10b in established intracranial glioblastoma: first steps toward the clinic Teplyuk, Nadiya M.; Uhlmann, Erik J.; Gabriely, Galina; Volfovsky, Natalia; Wang, Yang; Teng, Jian; Karmali, Priya; Marcusson, Eric; Peter, Merlene; Mohan, Athul; Kraytsberg, Yevgenya; Cialic, Ron; Chiocca, E. Antonio; Godlewski, Jakub; Tannous, Bakhos; Krichevsky, Anna M. Share Save
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