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Yuen Yi C. Tam

integrated nanotherapeutics inc., burnaby, bc v5g 4x4, canada

37H-index
95Paper Count
5.7KCitation Count
Published Papers 36
Publication Date
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Radiosensitization by Docetaxel Prodrug-Loaded Lipid Nanoparticles in Pancreatic Cancer Xenografts
errNanomaterials 2025, Vol. 15, Page 1521
IF4.3
err2025-10-05
err0
errOAAI
errAbdulaziz Alhussan; Nolan Jackson; Nancy Dos Santos; Sam Chen; Yuen Yi C. Tam; Devika B. Chithrani
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errSave
Lipid Nanoparticle and Liposome Reference Materials: Assessment of Size Homogeneity and Long-Term-70 °C and 4 °C Storage Stability
errLANGMUIR
IF3.9
err2023-02-07
err16
errOAAI
errJakubek, Zygmunt J.; Chen, Sam; Zaifman, Josh; Tam, Yuen Yi C.; Zou, Shan
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errSave
Development of lipid nanoparticles and liposomes reference materials (II): cytotoxic profiles
errSCIENTIFIC REPORTS
IF3.9
err2022-10-27
err23
errOAAI
errSyama, Krishnapriya; Jakubek, Zygmunt J.; Chen, Sam; Zaifman, Josh; Tam, Yuen Yi C.; Zou, Shan
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errSave
Lipid nanoparticles to silence androgen receptor variants for prostate cancer therapy
errJOURNAL OF CONTROLLED RELEASE
IF11.5
err2022-09-01
err12
errOAAI
errQuick, Joslyn; Dos Santos, Nancy; Cheng, Miffy H. Y.; Chander, Nisha; Brimacombe, Cedric A.; Kulkarni, Jayesh; van der Meel, Roy; Tam, Yuen Yi C.; Witzigmann, Dominik; Cullis, Pieter R.
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errSave
Synthesis and Characterization of Hybrid Lipid Nanoparticles Containing Gold Nanoparticles and a Weak Base Drug
errLANGMUIR
IF3.9
err2022-06-16
err8
PREAI
errZhigaltsev, Igor, V; Tam, Yuen Yi C.; Kulkarni, Jayesh A.; Cullis, Pieter R.
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errSave
Modular Lipid Nanoparticle Platform Technology for siRNA and Lipophilic Prodrug Delivery
errSMALL
IF12.1
err2021-08-01
err30
errOAAI
errvan Der Meel, Roy; Chen, Sam; Zaifman, Josh; Kulkarni, Jayesh A.; Zhang, Xu Ran S.; Tam, Ying K.; Bally, Marcel B.; Schiffelers, Raymond M.; Ciufolini, Marco A.; Cullis, Pieter R.; Tam, Yuen Yi C.
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errSave
Scalable Production of Lipid Nanoparticles Containing Amphotericin B
errLANGMUIR
IF3.9
err2021-06-08
err8
PREAI
errKulkarni, Jayesh A.; Chen, Sam; Tam, Yuen Yi C.
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errSave
Characterization of Lipid Nanoparticles Containing Ionizable Cationic Lipids Using Design-of-Experiments Approach
errLANGMUIR
IF3.9
err2021-01-13
err82
errOAAI
errTerada, Takeshi; Kulkarni, Jayesh A.; Huynh, Ariel; Chen, Sam; van der Meel, Roy; Tam, Yuen Yi C.; Cullis, Pieter R.
errShare
errSave
Synthesis and Anti-HCV Activity of Sugar-Modified Guanosine Analogues: Discovery of AL-611 as an HCV NS5B Polymerase Inhibitor for the Treatment of Chronic Hepatitis C
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-08-20
err18
PREAI
errWang, Guangyi; Dyatkina, Natalia; Prhavc, Marija; Williams, Caroline; Serebryany, Vladimir; Hu, Yujian; Huang, Yongfei; Wu, Xiangyang; Chen, Tongqian; Huang, Wensheng; Rajwanshi, Vivek K.; Deval, Jerome; Fung, Amy; Jin, Zhinan; Stoycheva, Antitsa; Shaw, Kenneth; Gupta, Kusum; Tam, Yuen; Jekle, Andreas; Smith, David B.; Beigelman, Leonid
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errSave
Spontaneous, solvent-free entrapment of siRNA within lipid nanoparticles
errNANOSCALE
IF5.1
err2020-01-01
err43
PREAI
errKulkarni, Jayesh A.; Thomson, Sarah B.; Zaifman, Josh; Leung, Jerry; Wagner, Pamela K.; Hill, Austin; Tam, Yuen Yi C.; Cullis, Pieter R.; Petkau, Terri L.; Leavitt, Blair R.
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errSave
Synthesis and Anti-HCV Activities of 4′-Fluoro-2′-Substituted Uridine Triphosphates and Nucleotide Prodrugs: Discovery of 4′-Fluoro-2′-C-methyluridine 5′-Phosphoramidate Prodrug (AL-335) for the Treatment of Hepatitis C Infection
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2019-04-05
err32
PREAI
errWang, Guangyi; Dyatkina, Natalia; Prhavc, Marija; Williams, Caroline; Serebryany, Vladimir; Hu, Yujian; Huang, Yongfei; Wan, Jinqiao; Wu, Xiangyang; Deval, Jerome; Fung, Amy; Jin, Zhinan; Fan, Hua; Shaw, Kenneth; Kang, Hyunsoon; Zhang, Qingling; Tam, Yuen; Stoycheva, Antitsa; Jekle, Andreas; Smith, David B.; Beigelman, Leonid
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errSave
On the role of helper lipids in lipid nanoparticle formulations of siRNA
errNANOSCALE
IF5.1
err2019-01-01
err262
PREAI
errKulkarni, Jayesh A.; Witzigmann, Dominik; Leung, Jerry; Tam, Yuen Yi C.; Cullis, Pieter R.
errShare
errSave
Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads
errNANOSCALE
IF5.1
err2019-01-01
err112
errOAAI
errKulkarni, Jayesh A.; Witzigmann, Dominik; Leung, Jerry; van der Meel, Roy; Zaifman, Josh; Darjuan, Maria M.; Grisch-Chan, Hiu Man; Thony, Beat; Tam, Yuen Yi C.; Cullis, Pieter R.
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errSave
Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acids
errJOURNAL OF CONTROLLED RELEASE
IF11.5
err2018-09-01
err43
PREAI
errChen, Sam; Zaifman, Josh; Kulkarni, Jayesh A.; Zhigaltsev, Igor V.; Tam, Ying K.; Ciufolini, Marco A.; Tam, Yuen Yi C.; Cullis, Pieter R.
errShare
errSave
On the Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA
errACS NANO
IF16
err2018-04-03
err390
errOAAI
errKulkarni, Jayesh A.; Darjuan, Maria M.; Mercer, Joanne E.; Chen, Sam; van der Meel, Roy; Thewalt, Jenifer L.; Tam, Yuen Yi C.; Cullis, Pieter R.
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errSave
Lipid nanoparticle delivery of glucagon receptor siRNA improves glucose homeostasis in mouse models of diabetes
errMOLECULAR METABOLISM
IF6.6
err2017-10-01
err29
errOAAI
errNeumann, Ursula H.; Ho, Jessica S. S.; Chen, Sam; Tam, Yuen Yi C.; Cullis, Pieter R.; Kieffer, Timothy J.
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errSave
Rapid synthesis of lipid nanoparticles containing hydrophobic inorganic nanoparticles
errNANOSCALE
IF5.1
err2017-01-01
err52
PREAI
errKulkarni, Jayesh A.; Tam, Yuen Yi C.; Chen, Sam; Tam, Ying K.; Zaifman, Josh; Cullis, Pieter R.; Biswas, Souvik
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errSave
The Niemann-Pick C1 Inhibitor NP3.47 Enhances Gene Silencing Potency of Lipid Nanoparticles Containing siRNA
errMOLECULAR THERAPY
IF12
err2016-12-01
err42
errOAAI
errWang, Haitang; Tam, Yuen Yi C.; Chen, Sam; Zaifman, Josh; van der Meel, Roy; Ciufolini, Marco A.; Cullis, Pieter R.
errShare
errSave
Activation Pathway of a Nucleoside Analog Inhibiting Respiratory Syncytial Virus Polymerase
errACS CHEMICAL BIOLOGY
IF3.8
err2016-11-22
err15
errOAAI
errJordan, Paul C.; Stevens, Sarah K.; Tam, Yuen; Pemberton, Ryan P.; Chaudhuri, Shuvam; Stoycheva, Antitsa D.; Dyatkina, Natalia; Wang, Guangyi; Symons, Julian A.; Deval, Jerome; Beigelman, Leo
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errSave
Influence; particle size on the in vivo potency; lipid nanoparticle formulations; siRNA
errJOURNAL OF CONTROLLED RELEASE
IF11.5
err2016-08-01
err270
PREAI
errChen, Sam; Tam, Yuen Yi C.; Lin, Paulo J. C.; Sung, Molly M. H.; Tam, Ying K.; Cullis, Pieter R.
errShare
errSave

Research Directions

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Co-authors
Cooperation Journals
R
Ruedi Aebersold
H-index: 198 · Papers: 1.2K
P
Pieter R. Cullis
H-index: 108 · Papers: 478
A
Alexey I. Nesvizhskii
H-index: 91 · Papers: 445
B
Blair R. Leavitt
H-index: 86 · Papers: 390
R
Raymond M. Schiffelers
H-index: 85 · Papers: 343
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