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M

Michael J. Skynner

bicycle therapeutics

22H-index
74Paper Count
1.7KCitation Count
Published Papers 13
Publication Date
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Bismuth Bicycles
errJournal of Peptide Science
IF1.8
err2026-03-01
err0
PREAI
errVoss, Saan; Sagar, Amin; Tiberghien, Arnaud; Hughes, Richard J. L.; Chen, Liuhong; Rioja, Inmaculada; Frigerio, Mark; Skynner, Michael J.; Spring, David R.
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Utilizing Constrained Bicyclic Peptides for In Vitro Diagnostics
errACS Nano
IF16
err2026-02-13
err0
errOAAI
errAndré Shamsabadi; Adam Creamer; Christy J. Sadler; Aida Abdelwahed; Katherine U. Gaynor; Yuliya Demydchuk; Gabriela Ivanova-Berndt; Katerine Van Rietschoten; Paul Beswick; Liuhong Chen; Gustavo Arruda Bezerra; Aleksei Lulla; Paul Brear; Marko Hyvönen; Michael J. Skynner; Molly M. Stevens
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errSave
Design of Bicyclic Peptide Tandems Mimicking the Homodimeric GDF15 Protein to Inhibit GDF15–GFRaL–RET Complex Cell Signaling
errJournal of Medicinal Chemistry
IF6.8
err2025-10-09
err0
PREAI
errAnaïs F. M. Noisier; Jenny Sandmark; Fredrik Edfeldt; Anna Backmark; Johan Broddefalk; Joanna Wandzik; Ulrik Jurva; Margareta Ek; Carina A. Johansson; Louise Barlind; Jenny Gunnarsson; Janna M. Bigalke; Yafeng Xue; Andrey I. Frolov; Cecilia Kankkonen; Robert G. Roth; Maria Fritsch; Sophie Watcham; Katerine van Rietschoten; Gemma E. Mudd; Helen Harrison; Liuhong Chen; Michael J. Skynner; David J. Craik; Sunay V. Chankeshwara; Malin Lemurell
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errSave
High-Throughput Identification and Characterization of LptDE-Binding Bicycle Peptides Using Phage Display and Cryo-EM
errJournal of Medicinal Chemistry
IF6.8
err2025-10-06
err0
errOAAI
errShenaz Allyjaun; Emily Dunbar; Steven W. Hardwick; Sarah Newell; Finn Holding; Catherine E Rowland; Megan A. St. Denis; Simone Pellegrino; Gustavo Arruda Bezerra; Nikolaos Bournakas; Dimitri Y. Chirgadze; Lee Cooper; Giulia Paris; Nick Lewis; Peter Brown; Michael J. Skynner; Michael J Dawson; Paul Beswick; Julia Hubbard; Bert van den Berg; Hector Newman
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errSave
Rational design of cyclic peptides, with an emphasis on bicyclic peptides
errCURRENT OPINION IN STRUCTURAL BIOLOGY
IF7
err2025-06-01
err0
errOAAI
errRowland, Catherine E.; Bezerra, Gustavo Arruda; Skynner, Michael J.
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errSave
Investigating Penetration and Antimicrobial Activity of Vector-Bicycle Conjugates
errACS INFECTIOUS DISEASES
IF3.8
err2024-06-12
err0
errOAAI
errHadjicharalambous, Andreas; Newman, Hector; Lewis, Nick; Rowland, Catherine; Bournakas, Nikolaos; Stanway, Steven J.; Dawson, Michael; Skynner, Michael J.; Beswick, Paul
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Discovery and Characterization of a Bicyclic Peptide (Bicycle) Binder to Thymic Stromal Lymphopoietin
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-01-29
err0
PREAI
errNarjes, Frank; Edfeldt, Fredrik; Petersen, Jens; Oster, Linda; Hamblet, Corinne; Bird, James; Bold, Peter; Rae, Rebecca; Back, Elisabeth; Stomilovic, Stina; Zlatoidsky, Pavol; Svensson, Tor; Hidestal, Lotta; Kunalingam, Lavaniya; Shamovsky, Igor; De Maria, Leonardo; Gordon, Euan; Lewis, Richard J.; Watcham, Sophie; van Rietschoten, Katerine; Mudd, Gemma E.; Harrison, Helen; Chen, Liuhong; Skynner, Michael J.
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Structure-Guided Chemical Optimization of Bicyclic Peptide (Bicycle) Inhibitors of Angiotensin-Converting Enzyme 2
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-07-11
err2
PREAI
errHarman, Maximilian A. J.; Stanway, Steven J. J.; Scott, Heather; Demydchuk, Yuliya; Bezerra, Gustavo Arruda; Pellegrino, Simone; Chen, Liuhong; Brear, Paul; Lulla, Aleksei; Hyvonen, Marko; Beswick, Paul J. J.; Skynner, Michael J. J.
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errSave
Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2
errNATURE COMMUNICATIONS
IF15.7
err2023-06-16
err9
errOAAI
errGaynor, Katherine U. U.; Vaysburd, Marina; Harman, Maximilian A. J.; Albecka, Anna; Jeffrey, Phillip; Beswick, Paul; Papa, Guido; Chen, Liuhong; Mallery, Donna; McGuinness, Brian; Van Rietschoten, Katerine; Stanway, Steven; Brear, Paul; Lulla, Aleksei; Ciazynska, Katarzyna; Chang, Veronica T. T.; Sharp, Jo; Neary, Megan; Box, Helen; Herriott, Jo; Kijak, Edyta; Tatham, Lee; Bentley, Eleanor G. G.; Sharma, Parul; Kirby, Adam; Han, Ximeng; Stewart, James P. P.; Owen, Andrew; Briggs, John A. G.; Hyvonen, Marko; Skynner, Michael J. J.; James, Leo C. C.
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errSave
Modulation of natural killer cell immune response to tumor with novel synthetic tumor-immune cell agonist, NKTICA(r)
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errDufort, Fay; Leitheiser, Christopher J.; Ho, Kathleen; Ezell, Tucker; Rezvaya, Alexandra; Brown, Peter; Chen, Liuhong; Brandish, Philip; McDonnell, Kevin; Skynner, Michael; Keen, Nicholas
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errSave
Antimicrobial and Cell-Penetrating Peptides: Understanding Penetration for the Design of Novel Conjugate Antibiotics
errANTIBIOTICS-BASEL
IF4.6
err2022-11-16
err24
errOAAI
errHadjicharalambous, Andreas; Bournakas, Nikolaos; Newman, Hector; Skynner, Michael J. J.; Beswick, Paul
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errSave
BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2022-09-16
err29
errOAAI
errRigby, Michael; Bennett, Gavin; Chen, Liuhong; Mudd, Gemma E.; Harrison, Helen; Beswick, Paul J.; Van Rietschoten, Katerine; Watcham, Sophie M.; Scott, Heather S.; Brown, Amy N.; Park, Peter U.; Campbell, Carly; Haines, Eric; Lahdenranta, Johanna; Skynner, Michael J.; Jeffrey, Phil; Keen, Nicholas; Lee, Kevin
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An Assay for Periplasm Entry Advances the Development of Chimeric Peptide Antibiotics
errACS INFECTIOUS DISEASES
IF3.8
err2020-07-22
err2
PREAI
errWagstaff, James M.; Balmforth, Matthew; Lewis, Nick; Dods, Rachel; Rowland, Catherine; van Rietschoten, Katerine; Chen, Liuhong; Harrison, Helen; Skynner, Michael J.; Dawson, Michael; Ivanova-Berndt, Gabriela; Beswick, Paul
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Research Directions

No research directions
Co-authors
Cooperation Journals
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David J. Craik
H-index: 113 · Papers: 1.4K
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John A. G. Briggs
H-index: 81 · Papers: 335
P
Peter de Nully Brown
H-index: 79 · Papers: 568
D
David R. Spring
H-index: 67 · Papers: 545
L
Leo C. James
H-index: 60 · Papers: 210
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