Not logged in The Pathway to Proof-of-Concept for BNC210, a Negative Allosteric Modulator of the Alpha-7 Nicotinic Acetylcholine Receptor (nAChR), for Treatment of Psychiatric Disease Rolan, Paul; Doolin, Elizabeth; Paul, Dharam; Crossman, Julia; Odontiadis, Michael; Danjou, Philippe; Smith, Mark; Papapetropoulos, Spyros Share Save
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Discovery of azaspirocyclic 1H-3,4,5-Trisubstitued pyrazoles as novel G2019S-LRRK2 selective kinase inhibitors Lesniak, Robert K.; Nichols, R. Jeremy; Schonemann, Marcus; Zhao, Jing; Gajera, Chandresh R.; Lam, Grace; Nguyen, Khanh C.; Langston, J. William; Smith, Mark; Montine, Thomas J. Share Save
Radiosynthesis and initial preclinical evaluation of [11C]AZD1283 as a potential P2Y12R PET radiotracer Jackson, Isaac M.; Buccino, Pablo J.; Azevedo, E. Carmen; Carlson, Mackenzie L.; Luo, Audrey S. Z.; Deal, Emily M.; Kalita, Mausam; Reyes, Samantha T.; Shao, Xia; Beinat, Corinne; Nagy, Sydney C.; Chaney, Aisling M.; Anders, David A.; Scott, Peter J. H.; Smith, Mark; Shen, Bin; James, Michelle L. Share Save
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Discovery of 1H-Pyrazole Biaryl Sulfonamides as Novel G2019S-LRRK2 Kinase Inhibitors Lesniak, Robert K.; Nichols, R. Jeremy; Schonemann, Marcus; Zhao, Jing; Gajera, Chandresh R.; Lam, Grace; Nguyen, Khanh C.; Langston, J. William; Smith, Mark; Montine, Thomas J. Share Save
Discovery of G2019S-Selective Leucine Rich Repeat Protein Kinase 2 inhibitors with in vivo efficacy Lesniak, Robert K.; Nichols, R. Jeremy; Schonemann, Marcus; Zhao, Jing; Gajera, Chandresh R.; Fitch, William L.; Lam, Grace; Nguyen, Khanh C.; Smith, Mark; Montine, Thomas J. Share Save
Does mismatch negativity have utility for NMDA receptor drug development in depression? Murphy, Nicholas; Lijffijt, Marijn; Ramakrishnan, Nithya; Vo-Le, Bylinda; Vo-Le, Brittany; Iqbal, Sidra; Iqbal, Tabish; O'Brien, Brittany; Smith, Mark A.; Swann, Alan C.; Mathew, Sanjay J. Share Save
Effect of mGluR2 positive allosteric modulation on frontostriatal working memory activation in schizophrenia Wolf, Daniel H.; Zheng, David; Kohler, Christian; Turetsky, Bruce I.; Ruparel, Kosha; Satterthwaite, Theodore D.; Elliott, Mark A.; March, Mary E.; Cross, Alan J.; Smith, Mark A.; Zukin, Stephen R.; Gur, Ruben C.; Gur, Raquel E. Share Save
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Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamine Kokkinou, Michelle; Irvine, Elaine E.; Bonsall, David R.; Natesan, Sridhar; Wells, Lisa A.; Smith, Mark; Glegola, Justyna; Paul, Eleanor J.; Tossell, Kyoko; Veronese, Mattia; Khadayate, Sanjay; Dedic, Nina; Hopkins, Seth C.; Ungless, Mark A.; Withers, Dominic J.; Howes, Oliver D. Share Save
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Modulation of SF1 Neuron Activity Coordinately Regulates Both Feeding Behavior and Associated Emotional States Viskaitis, Paulius; Irvine, Elaine E.; Smith, Mark A.; Choudhury, Agharul I.; Alvarez-Curto, Elisa; Glegola, Justyna A.; Hardy, Darran G.; Pedroni, Silvia M. A.; Pessoa, Maria R. Paiva; Fernando, Anushka B. P.; Katsouri, Loukia; Sardini, Alessandro; Ungless, Mark A.; Milligan, Graeme; Withers, Dominic J. Share Save
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SELF-REACTIVE IGE EXACERBATES INTERFERON RESPONSES ASSOCIATED WITH AUTOIMMUNITY Sanjuan, M. A.; Henault, J.; Riggs, J.; Karnell, J. L.; Liarski, V.; Shirinian, L.; Xu, L.; Casey, K.; Smith, M. A.; Khatry, D.; Clarke, L.; Herbst, R.; Ettinger, R.; Petri, M.; Clark, M. R.; Mustelin, T.; Kolbeck, R. Share Save
Comparing the actions of lanicemine and ketamine in depression: key role of the anterior cingulate Downey, Darragh; Dutta, Arpan; McKie, Shane; Dawson, Gerard R.; Dourish, Colin T.; Craig, Kevin; Smith, Mark A.; McCarthy, Dennis J.; Harmer, Catherine J.; Goodwin, Guy M.; Williams, Steve; Deakin, J. F. William Share Save
Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function Yavari, Arash; Stocker, Claire J.; Ghaffari, Sahar; Wargent, Edward T.; Steeples, Violetta; Czibik, Gabor; Pinter, Katalin; Bellahcene, Mohamed; Woods, Angela; de Morentin, Pablo B. Martinez; Cansell, Celine; Lam, Brian Y. H.; Chuster, Andre; Petkevicius, Kasparas; Nguyen-Tu, Marie-Sophie; Martinez-Sanchez, Aida; Pullen, Timothy J.; Oliver, Peter L.; Stockenhuber, Alexander; Nguyen, Chinh; Lazdam, Merzaka; O'Dowd, Jacqueline F.; Harikumar, Parvathy; Toth, Monika; Beall, Craig; Kyriakou, Theodosios; Parnis, Julia; Sarma, Dhruv; Katritsis, George; Wortmann, Diana D. J.; Harper, Andrew R.; Brown, Laurence A.; Willows, Robin; Gandra, Silvia; Poncio, Victor; de Oliveira Figueiredo, Marcio J.; Qi, Nathan R.; Peirson, Stuart N.; McCrimmon, Rory J.; Gereben, Balazs; Tretter, Laszlo; Fekete, Csaba; Redwood, Charles; Yeo, Giles S. H.; Heisler, Lora K.; Rutter, Guy A.; Smith, Mark A.; Withers, Dominic J.; Carling, David; Sternick, Eduardo B.; Arch, Jonathan R. S.; Cawthome, Michael A.; Watkins, Hugh; Ashrafian, Houman Share Save
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