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SaveShare Save Share Save Share Save Share Save Share Save Share Save Structural Optimization and Structure-Activity Relationship of 1H-Pyrazole-4-carboxylic Acid Derivatives as DNA 6mA Demethylase ALKBH1 Inhibitors and Their Antigastric Cancer Activity
Li, Feng; Xiong, Liang; Zhang, Jian; Guo, Yinping; Xu, Ke; Xiong, Zijie; Wang, Yuyang; Ji, Shanmian; Tong, Aiping; Li, Linli; Yang, Shengyong Share Save Identification of a new class of activators of the Hippo pathway with antitumor activity in vitro and in vivoLin, Guifeng; Xia, Anjie; Qiao, Jingxin; Zhang, Hailin; Chen, Pei; Zhou, Pei; Hu, Qian; Xiang, Zhiyu; Zhang, Shiyu; Li, Linli; Yang, Shengyong Share Save PocketFlow is a data-and-knowledge-driven structure-based molecular generative modelJiang, Yuanyuan; Zhang, Guo; You, Jing; Zhang, Hailin; Yao, Rui; Xie, Huanzhang; Zhang, Liyun; Xia, Ziyi; Dai, Mengzhe; Wu, Yunjie; Li, Linli; Yang, Shengyong Share Save Share Save Discovery of a novel pyroptosis inhibitor acting though modulating glutathionylation to suppress NLRP3-related signal pathwayZhou, Nenghua; Zhang, Yun; Jiao, Yan; Nan, Jinshan; Xia, Anjie; Mu, Bo; Lin, Guifeng; Li, Xun; Zhang, Shanshan; Yang, Shengyong; Li, Linli Share Save From Hit to Lead: Structure-Based Optimization of Novel Selective Inhibitors of Receptor-Interacting Protein Kinase 1 (RIPK1) for the Treatment of Inflammatory DiseasesZhang, Liting; Li, Yueshan; Tian, Chenyu; Yang, Ruicheng; Wang, Yifei; Xu, Haixing; Zhu, Qiucheng; Chen, Shasha; Li, Linli; Yang, Shengyong Share Save Discovery and structure-activity relationship studies of novel a-ketoamide derivatives targeting the SARS-CoV-2 main proteaseHuang, Chong; Zeng, Rui; Qiao, Jingxin; Quan, Baoxue; Luo, Ronghua; Huang, Qiao; Guo, Nihong; Li, Yueyue; Long, Xinyan; Ma, Ronggang; Xia, Anjie; Fang, Zhen; Wang, Yifei; Li, Yueshan; Zheng, Yongtang; Li, Linli; Lei, Jian; Yang, Shengyong Share Save Discovery of a potent, selective and cell active inhibitor of m6A demethylase ALKBH5(vol 238, 114446, 2022)Fang, Zhen; Mu, Bo; Liu, Yang; Guo, Nihong; Xiong, Liang; Guo, Yinping; Xia, Anjie; Zhang, Rong; Zhang, Hailin; Yao, Rui; Fan, Yan; Li, Linli; Yang, Shengyong; Xiang, Rong Share Save Share Save Discovery of [1,2,3]Triazolo[4,5-c]quinoline Derivatives as a New Class of Ataxia-Telangiectasia Mutated Kinase InhibitorsZhang, Shiyu; Zhou, Pei; Liu, Jingming; Xia, Anjie; Lin, Guifeng; Xiang, Zhiyu; Fang, Zhen; Yang, Xin; Qiao, Jingxin; Hu, Qian; Zhang, Jiahao; Zhao, Jinlong; Li, Linli Share Save Non-classical ferroptosis inhibition by a small molecule targeting PHB2Yang, Wei; Mu, Bo; You, Jing; Tian, Chenyu; Bin, Huachao; Xu, Zhiqiang; Zhang, Liting; Ma, Ronggang; Wu, Ming; Zhang, Guo; Huang, Chong; Li, Linli; Shao, Zhenhua; Dai, Lunzhi; Desaubry, Laurent; Yang, Shengyong Share Save Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitorLi, Yueshan; Zhang, Liting; Wang, Yifei; Zou, Jun; Yang, Ruicheng; Luo, Xinling; Wu, Chengyong; Yang, Wei; Tian, Chenyu; Xu, Haixing; Wang, Falu; Yang, Xin; Li, Linli; Yang, Shengyong Share Save Discovery of Small Molecule Agonist of Gonadotropin-Releasing Hormone Receptor (GnRH1R)Yang, Xin; Lin, Guifeng; Xia, Anjie; Liu, Jingming; Zhang, Shiyu; Zhou, Pei; Wang, Yiwei; Zhang, Jiahao; Zhou, Yangli; Chen, Pei; Wang, Yifei; Zheng, Tao; Li, Linli; Yang, Shengyong Share Save 
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