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Alex Zhavoronkov

insilico medicine ai limited

70H-index
443Paper Count
1.9WCitation Count
Published Papers 154
Publication Date
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NDRG1 expression in cancers confers dependence on DNA damage repair and sensitivity to quinacrine
errScience Signaling
IF6.6
err2026-07-21
err0
PREAI
errGarik V. Mkrtchyan; Alexander Veviorskiy; Zarah G. Meisen; Michael A. Petr; Tobias Clausen Mercurio; Daniela Bakula; Peter Sykora; Li-Wei Kuo; Dean S. Rosenthal; Cynthia M. Simbulan-Rosenthal; Peiran Zhang; Qiuqiong Tang; Andreyan N. Osipov; Ivan V. Ozerov; Alex Aliper; Alex Zhavoronkov; Morten Scheibye-Knudsen
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Target identification and assessment in the era of AI
errNature Reviews Drug Discovery
IF101.8
err2026-04-20
err0
PREAI
errFrank W. Pun; Dmitriy Podolskiy; Evgeny Izumchenko; Andrew Mortlock; Tudor I. Oprea; Morten Scheibye-Knudsen; Kristen Fortney; Eric Morgen; Feng Ren; Alex Zhavoronkov
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An Internal Sulfur-Lone Pair Interaction Enabled the Discovery of Potent and Sub-Family Selective PKMYT1 Inhibitors
errChemMedChem
IF3.4
err2026-03-27
err0
PREAI
errWang, Yazhou; Wang, Chao; Wang, Xiaomin; Liu, Tingting; Cai, Xin; Zhang, Man; Aliper, Alex; Ren, Feng; Ding, Xiao; Zhavoronkov, Alex
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errSave
Recent advance in macrocyclic CDK inhibitors
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2025-12-01
err0
PREAI
errZheng, Jiamin; Zhang, Zhisen; Liu, Jinxin; Shi, Ryan; Ren, Feng; Zhavoronkov, Alex; Ding, Xiao
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errSave
Design, Synthesis and Biological Evaluation of Novel, Potent, Selective and Orally Available DGKα Inhibitors for the Treatment of Tumors
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-12-01
err0
PREAI
errLu, Hongfu; Shi, Sujing; Yu, Huaxing; Sun, Deheng; Zhang, Haoyu; Cui, Hui; Cai, Xin; Ding, Xiao; Chen, Shan; Zhang, Man; Liu, Jinxin; Shi, Ryan; Aliper, Alex; Ren, Feng; Zhavoronkov, Alex
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errSave
Engineering the Future of Longevity R&D: The Case for AI-Driven, Integrated Biotechnology Ecosystems
errAGING AND DISEASE
IF6.9
err2025-12-01
err0
PREAI
errZhavoronkov, Alex; Leung, Chuen Yan
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errSave
Discovery of a bifunctional PKMYT1-targeting PROTAC empowered by AI-generation
errNature Communications
IF15.7
err2025-11-28
err0
errOAAI
errYazhou Wang; Xiaomin Wang; Tingting Liu; Chao Wang; Qingshuo Meng; Fanye Meng; Jiaojiao Yu; Jinxin Liu; Yaya Fan; David Gennert; Frank W. Pun; Alex Aliper; Feng Ren; Man Zhang; Xin Cai; Xiao Ding; Alex Zhavoronkov
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errSave
Uncovering the transcriptomic basis of endoxifen resistance in ER+ breast cancer cells: Insights from bioinformatics analysis
errCancer Treatment and Research Communications
IF2.4
err2025-11-01
err0
errOAAI
errRemmel, H. Lawrence; Hammer, Sandra S.; Hawse, John R.; Shneyderman, Anastasia; Veviorskiy, Alexander; Alawi, Khadija M.; Korzinkin, Mikhail; Zhavoronkov, Alex; Quay, Steven C.
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errSave
Discovery and Biological Evaluation of Novel, Potent, and Orally Available CBLB Inhibitors
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-11-01
err0
PREAI
errMeng, Fanye; Cao, Zhongying; Liu, Jinxin; Wang, Yazhou; Ning, Zhilin; Yu, Jiaojiao; Fan, Yaya; Chen, Shan; Zhang, Man; Pun, Frank W.; Aliper, Alex; Ren, Feng; Cai, Xin; Ding, Xiao; Zhavoronkov, Alex
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errSave
Evaluation of (Z)-endoxifen as a potential therapy for glioblastoma multiforme through computational and experimental analyses
errSCIENTIFIC REPORTS
IF3.9
err2025-10-31
err0
errOAAI
errShneyderman, Anastasia; Hammer, Sandra S.; Remmel, H. Lawrence; Veviorskiy, Alexander; Alawi, Khadija M.; Ustiugova, Alina; Korzinkin, Mikhail; Zhavoronkov, Alex; Quay, Steven C.
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errSave
Modelling sex differences of neurological disorders in vitro
errNature Reviews Bioengineering
IF37.6
err2025-10-01
err0
PREAI
errCastro-Aldrete, Laura; Einsiedler, Melanie; Cuni-Lopez, Carla; Vanhaelen, Quentin; Silvestri, Antonia; Ferretti, Maria Teresa; de Gennaro, Martina Elena; Putignano, Guido; Guix, Maria; Marino, Nicola; Galea, Liisa A. M.; Lenk, Kerstin; Paoletti, Samantha; Zhavoronkov, Alex; Santuccione Chadha, Antonella
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errSave
AlphaFold Kinase Optimizer: Enhancing Virtual Screening Performance Through Automated Refinement of AlphaFold-Based Kinase Structures
errPROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
IF2.8
err2025-09-01
err0
PREAI
errEvteev, Sergei; Ivanenkov, Yan; Aiginin, Andrew; Kuznetsov, Maksim; Shayakhmetov, Rim; Knyazev, Maksim; Bezrukov, Dmitry; Malyshev, Alex; Malkov, Maxim; Aliper, Alex; Zhavoronkov, Alex
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errSave
Traf2- and Nck-interacting kinase inhibitors: a patent review (2008–2024)
errExpert Opinion on Therapeutic Patents
IF4.6
err2025-08-20
err0
PREAI
errLuoheng Qin; Vladimir Aladinskiy; David Gennert; Xin Cheng; Jinxin Liu; Tingting Liu; Feng Ren; Alex Zhavoronkov
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errSave
From Clock to Clock: Therapeutic Target Discovery for Aging and Age-Related Diseases
errAgeing Research Reviews
IF12.4
err2025-08-12
err0
errOAAI
errJianjiu Chen; Geoffrey Ho Duen Leung; Howell Leung; Alina Ustiugova; Anastasia Shneyderman; Mike Korzinkin; David Gennert; Frank W. Pun; Alex Aliper; Feng Ren; Alex Zhavoronkov
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errSave
Rational Design and Identification of ISM7594 as a Tissue-Agnostic FGFR2/3 Inhibitor
errJournal of Medicinal Chemistry
IF6.8
err2025-06-25
err0
PREAI
errYazhou Wang; Jinxin Liu; Yihong Zhang; Jichen Zhao; Chao Wang; Hui Cui; Fanye Meng; Alex Aliper; Tao Liang; Feng Yan; Feng Ren; Jiong Lan; Qiang Lu; Fusheng Zhou; Xin Cai; Xiao Ding; Alex Zhavoronkov
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errSave
Organization of the Proteostasis Network of Membraneless Organelles
errAdvanced Science
IF14.1
err2025-06-11
err0
errOAAI
errChristine M. Lim; Yuqi Bian; Alicia González Díaz; Frank Pun; Alex Zhavoronkov; Richard I. Morimoto; Michele Vendruscolo
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errSave
Identification of Novel pan-KRAS Inhibitors via Structure-Based Drug Design; Scaffold Hopping; and Biological Evaluation
errACS Medicinal Chemistry Letters
IF4
err2025-06-05
err0
PREAI
errVladimir Aladinskiy; Alexey B. Mantsyzov; Chris Kruse; Alexey Noev; Rostislav Petrov; Viktor Reshetnikov; Sujing Shi; Xiao Ding; Xin Cai; Alex Aliper; Alex Zhavoronkov; Feng Ren
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errSave
AI-Driven Drug Target Screening Platform Identified Oncogene CACNA2D1 Activated by Enhancer Infestation in Epstein-Barr Virus-Associated Nasopharyngeal Carcinoma
errINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
err2025-05-14
err0
errOAAI
errChung, Dittman Lai-Shun; Leung, Geoffrey Ho Duen; Liu, Songran; Lok, Sarah Wing Yan; Xin, Ying; Xia, Yunfei; Zhavoronkov, Alex; Pun, Frank W.; Ng, Wai-Tong; Dai, Wei
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errSave
Discovery of Novel SIK2/3 Inhibitors for the Potential Treatment of MEF2C+Acute Myeloid Leukemia (AML)
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-03-20
err0
PREAI
errZhu, Wei; Zhao, Pei; Liu, Tingting; Gao, Feng; Li, Qi; Cai, Xin; Zhang, Man; Aliper, Alex; Ren, Feng; Zhavoronkov, Alex
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errSave
Innovations in aging biology: highlights from the ARDD emerging science & technologies workshop
errNPJ AGING
IF6
err2025-02-18
err0
errOAAI
errUnfried, Maximilian; Schmauck-Medina, Tomas; Amin, Neal D.; Boyden, Edward S.; Fuellen, Georg; Han, Jing-Dong Jackie; Hanna, Jacob H.; Heckenbach, Indra; Khodosevich, Konstantin; Melton, Lisa; Moeendarbary, Emad; Moon, Tae Seok; Peleg, Shahaf; Sandberg, Anders; Shi, Lingyan; Bakula, Daniela; Zhavoronkov, Alex; Scheibye-Knudsen, Morten
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Research Directions

No research directions
Co-authors
Cooperation Journals
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Luigi Ferrucci
H-index: 237 · Papers: 2.6K
M
M Snyder
H-index: 210 · Papers: 3.3K
G
George M. Church
H-index: 190 · Papers: 1.3K
S
Steven R. Cummings
H-index: 167 · Papers: 944
S
Steve Horvath
H-index: 150 · Papers: 941
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