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Development of Brain Penetrant Pyridazine Pantothenate Kinase Activators Tangallapally, Rajendra; Subramanian, Chitra; Yun, Mi-Kyung; Edwards, Anne; Sharma, Lalit Kumar; Yang, Lei; Creed, Katie; Wang, Jina; Jackowski, Suzanne; Rock, Charles O.; White, Stephen W.; Lee, Richard E. Share Save
Pantothenate Kinase Activation Restores Brain Coenzyme A in a Mouse Model of Pantothenate Kinase-Associated Neurodegeneration Subramanian, Chitra; Frank, Matthew W.; Sukhun, Rajaa; Henry, Christopher E.; Wade, Anna; Harden, Mallory E.; Rao, Satish; Tangallapally, Rajendra; Yun, Mi-Kyung; White, Stephen W.; Lee, Richard E.; Sinha, Uma; Rock, Charles O.; Jackowski, Suzanne Share Save
Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential Slavish, Peter J.; Cuypers, Maxime G.; Rimmer, Mary Ashley; Abdolvahabi, Alireza; Jeevan, Trushar; Kumar, Gyanendra; Jarusiewicz, Jamie A.; Vaithiyalingam, Sivaraja; Jones, Jeremy C.; Bowling, John J.; Price, Jeanine E.; DuBois, Rebecca M.; Min, Jaeki; Webby, Richard J.; Rankovic, Zoran; White, Stephen W. Share Save
SB226, an inhibitor of tubulin polymerization, inhibits paclitaxel-resistant melanoma growth and spontaneous metastasis Deng, Shanshan; Banerjee, Souvik; Chen, Hao; Pochampally, Satyanarayana; Wang, Yuxi; Yun, Mi-Kyung; White, Stephen W.; Parmar, Keyur; Meibohm, Bernd; Hartman, Kelli L.; Wu, Zhongzhi; Miller, Duane D.; Li, Wei Share Save
Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma Singh, Shivendra; Abu-Zaid, Ahmed; Jin, Hongjian; Fang, Jie; Wu, Qiong; Wang, Tingting; Feng, Helin; Quarni, Waise; Shao, Ying; Maxham, Lily; Abdolvahabi, Alireza; Yun, Mi-Kyung; Vaithiyalingam, Sivaraja; Tan, Haiyan; Bowling, John; Honnell, Victoria; Young, Brandon; Guo, Yian; Bajpai, Richa; Pruett-Miller, Shondra M.; Grosveld, Gerard C.; Hatley, Mark; Xu, Beisi; Fan, Yiping; Wu, Gang; Chen, Eleanor Y.; Chen, Taosheng; Lewis, Peter W.; Rankovic, Zoran; Li, Yimei; Murphy, Andrew J.; Easton, John; Peng, Junmin; Chen, Xiang; Wang, Ruoning; White, Stephen W.; Davidoff, Andrew M.; Yang, Jun Share Save
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Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs Min, Jaeki; Mayasundari, Anand; Keramatnia, Fatemeh; Jonchere, Barbara; Yang, Seung Wook; Jarusiewicz, Jamie; Actis, Marisa; Das, Sourav; Young, Brandon; Slavish, Jake; Yang, Lei; Li, Yong; Fu, Xiang; Garrett, Shalandus H.; Yun, Mi-Kyung; Li, Zhenmei; Nithianantham, Stanley; Chai, Sergio; Chen, Taosheng; Shelat, Anang; Lee, Richard E.; Nishiguchi, Gisele; White, Stephen W.; Roussel, Martine F.; Potts, Patrick Ryan; Fischer, Marcus; Rankovic, Zoran Share Save
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X-ray Crystallography-Guided Design, Antitumor Efficacy, and QSAR Analysis of Metabolically Stable Cyclopenta-Pyrimidinyl Dihydroquinoxalinone as a Potent Tubulin Polymerization Inhibitor Banerjee, Souvik; Mahmud, Foyez; Deng, Shanshan; Ma, Lingling; Yun, Mi-Kyung; Fakayode, Sayo O.; Arnst, Kinsie E.; Yang, Lei; Chen, Hao; Wu, Zhongzhi; Lukka, Pradeep B.; Parmar, Keyur; Meibohm, Bernd; White, Stephen W.; Wang, Yuxi; Li, Wei; Miller, Duane D. Share Save
Design, Synthesis, and Biological Evaluation of Stable Colchicine-Binding Site Tubulin Inhibitors 6-Aryl-2-benzoyl-pyridines as Potential Anticancer Agents Chen, Hao; Deng, Shanshan; Albadari, Najah; Yun, Mi-Kyung; Zhang, Sicheng; Li, Yong; Ma, Dejian; Parke, Deanna N.; Yang, Lei; Seagroves, Tiffany N.; White, Stephen W.; Miller, Duane D.; Li, Wei Share Save
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Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer Slavish, P. Jake; Chi, Liying; Yun, Mi-Kyung; Tsurkan, Lyudmila; Martinez, Nancy E.; Jonchere, Barbara; Chai, Sergio C.; Connelly, Michele; Waddell, M. Brett; Das, Sourav; Neale, Geoffrey; Li, Zhenmei; Shadrick, William R.; Olsen, Rachelle R.; Freeman, Kevin W.; Low, Jonathan A.; Price, Jeanine E.; Young, Brandon M.; Bharatham, Nagakumar; Boyd, Vincent A.; Yang, Jun; Lee, Richard E.; Morfouace, Marie; Roussel, Martine F.; Chen, Taosheng; Savic, Daniel; Guy, R. Kiplin; White, Stephen W.; Shelat, Anang A.; Potter, Philip M. Share Save
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Colchicine Binding Site Agent DJ95 Overcomes Drug Resistance and Exhibits Antitumor Efficacy Arnst, Kinsie E.; Wang, Yuxi; Lei, Zi-Ning; Hwang, Dong-Jin; Kumar, Gyanendra; Ma, Dejian; Parke, Deanna N.; Chen, Qiang; Yang, Jinliang; White, Stephen W.; Seagroves, Tiffany N.; Chen, Zhe-Sheng; Miller, Duane D.; Li, Wei Share Save
Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indo1-3-yl)-1H-imidazol-4-yl)(3,4,5-trinnethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin Wang, Qinghui; Arnst, Kinsie E.; Wang, Yuxi; Kumar, Gyanendra; Ma, Dejian; White, Stephen W.; Miller, Duane D.; Li, Weimin; Li, Wei Share Save
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