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SaveIdentification of new ClpC1-NTD binders for Mycobacterium tuberculosis drug development (vol 15, 4146, 2025)
Weinhaupl, Katharina; Meuret, Louis; Desrat, Sandy; Roussi, Fanny; Morellet, Nelly; Beaupierre, Sandra; Guillou, Catherine; van Heijenoort, Carine; Abian, Olga; Vega, Sonia; Wolf, Ian; Akopian, Tatos; Krandor, Olga; Rubin, Eric; Velazquez-Campoy, Adrian; Gauto, Diego; Fraga, Hugo Share Save Share Save Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological FunctionJezequel, Gwenaelle; Grimanelli, Zoe; Guimard, Carole; Bigay, Joe''lle; Haddad, Juliano; Bignon, Jerome; Apel, Cecile; Steinmetz, Vincent; Askenatzis, Laurie; Levaique, Helene; Pradelli, Clara; Pham, Van Cuong; Huong, Doan T. M.; Litaudon, Marc; Gautier, Romain; El Kalamouni, Chaker; Antonny, Bruno; Desrat, Sandy; Mesmin, Bruno; Roussi, Fanny Share Save Share Save Structure-Based Design of a Lead Compound Derived from Natural Schweinfurthins with Antitumor Properties That Target Oxysterol-Binding ProteinJezequel, Gwenaelle; Rampal, Celine; Guimard, Carole; Kovacs, David; Polidori, Joel; Bigay, Joelle; Bignon, Jerome; Askenatzis, Laurie; Litaudon, Marc; Pham, Van-Cuong; Huong, Doan T. M.; Nguyen, Anvi Laetitia; Pruvost, Alain; Virolle, Thierry; Mesmin, Bruno; Desrat, Sandy; Antonny, Bruno; Roussi, Fanny Share Save VAP-A intrinsically disordered regions enable versatile tethering at membrane contact sitesSubra, Melody; Dezi, Manuela; Bigay, Joelle; Lacas-Gervais, Sandra; Cicco, Aurelie Di; Araujo, Ana Rita Dias; Abelanet, Sophie; Fleuriot, Lucile; Debayle, Delphine; Gautier, Romain; Patel, Amanda; Roussi, Fanny; Antonny, Bruno; Levy, Daniel; Mesmin, Bruno Share Save In vitro evaluation of NA1-115-7-loaded nanoemulsions, an MCL-1-specific inhibitor of natural origin, intended to treat B-cell lymphoproliferative disorders after oral administrationSeguy, Line; Daressy, Florian; Lahlil, Sophia; Corvaisier, Sophie; Dumontet, Vincent; Litaudon, Marc; Apel, Cecile; Roussi, Fanny; Wiels, Joelle; Robert, Aude; Groo, Anne-Claire; Malzert-Freon, Aurelie Share Save Share Save NA1-115-7, from Zygogynum pancheri, is a new selective MCL-1 inhibitor inducing the apoptosis of hematological cancer cells but non-toxic to normal blood cells or cardiomyocytesDaressy, Florian; Seguy, Line; Favre, Loetitia; Corvaisier, Sophie; Apel, Cecile; Groo, Anne-Claire; Litaudon, Marc; Dumontet, Vincent; Malzert-Freon, Aurelie; Desrat, Sandy; Roussi, Fanny; Robert, Aude; Wiels, Joelle Share Save Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL-1Daressy, Florian; Malard, Florian; Seguy, Line; Guerineau, Vincent; Apel, Cecile; Dumontet, Vincent; Robert, Aude; Groo, Anne-Claire; Litaudon, Marc; Bignon, Jerome; Desrat, Sandy; Malzert-Freon, Aurelie; Wiels, Joelle; Lescop, Ewen; Roussi, Fanny Share Save Share Save Molecular and cellular dissection of the oxysterol-binding protein cycle through a fluorescent inhibitorPeresse, Tiphaine; Kovacs, David; Subra, Melody; Bigay, Joelle; Tsai, Meng-Chen; Polidori, Joel; Gautier, Romain; Desrat, Sandy; Fleuriot, Lucile; Debayle, Delphine; Litaudon, Marc; Pham, Van-Cuong; Bignon, Jerome; Antonny, Bruno; Roussi, Fanny; Mesmin, Bruno Share Save Share Save Investigation of Premyrsinane and Myrsinane Esters in Euphorbia cupanii and Euphobia pithyusa with MS2LDA and Combinatorial Molecular Network Annotation PropagationNothias-Esposito, Melissa; Nothias, Louis Felix; Da Silva, Ricardo R.; Retailleau, Pascal; Zhang, Zheng; Leyssen, Pieter; Roussi, Fanny; Touboul, David; Paolini, Julien; Dorrestein, Pieter C.; Litaudon, Marc Share Save Antiviral Compounds from Codiaeum peltatum Targeted by a Multi-informative Molecular Networks ApproachOlivon, Florent; Remy, Simon; Grelier, Gwendal; Apel, Cecile; Eydoux, Cecilia; Guillemott, Jean-Claude; Neyts, Johan; Delang, Leen; Touboul, David; Roussi, Fanny; Litaudon, Marc Share Save Share Save Natural Inhibitors of the RhoA-p115 Complex from the Bark of Meiogyne bailloniiOlivon, Florent; Nothias, Louis-Felix; Dumontet, Vincent; Retailleau, Pascal; Berger, Sylvie; Ferry, Gilles; Cohen, William; Pfeiffer, Bruno; Boutin, Jean A.; Scalbert, Elisabeth; Roussi, Fanny; Litaudon, Marc Share Save Structurally Diverse Diterpenoids from Sandwithia guyanensisRemy, Simon; Olivon, Florent; Desrat, Sandy; Blanchard, Florent; Eparvier, Veronique; Leyssen, Pieter; Neyts, Johan; Roussi, Fanny; Touboul, David; Litaudon, Marc Share Save Dual inhibitors of the pro-survival proteins Bcl-2 and Mcl-1 derived from natural compound meiogynin AAbou Samra, Alma; Robert, Aude; Gov, Crystal; Favre, Loetitia; Eloy, Laure; Jacquet, Eric; Bignon, Jerome; Wiels, Joelle; Desrat, Sandy; Roussi, Fanny Share Save 
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