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Ulrike Garscha

greifswald university

29H-index
91Paper Count
2.1KCitation Count
Published Papers 49
Publication Date
Modifications in FLAP's second cytosolic loop influence 5-LOX interaction, inhibitor binding, and leukotriene formation
err2025-05-08
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errOAAI
errErik Romp; Katharina Rataj; Stefanie König; Marcia E. Newcomer; Oliver Werz; Ulrike Garscha
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Lead Optimization of Positive Allosteric KV7.2/3 Channel Modulators toward Improved Balance of Lipophilicity and Aqueous Solubility
err2025-04-08
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PREAI
errLemke, Jana; Mengers, Nadine; Schmidt, Louis; Schulig, Lukas; Koenig, Stefanie; Rosendahl, Pascal; Bartz, Frieda-Marie; Garscha, Ulrike; Bednarski, Patrick J.; Link, Andreas
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Structure-Guided Engineering of a Versatile Urethanase Improves Its Polyurethane Depolymerization Activity
err2025-02-07
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errOAAI
errLi, ZS; Han, X; Cong, L; Singh, P; Paiva, P; Branson, Y; Li, WS; Chen, YY; Jaradat, DMM; Lennartz, F; Bayer, T; Schmidt, L; Garscha, U; You, S; Fernandes, PA; Ramos, MJ; Bornscheuer, UT; Weber, G; Wei, R; Liu, WD
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Structural Elucidation of a Metagenomic Urethanase and Its Engineering Towards Enhanced Hydrolysis Profiles
err2024-08-16
err8
errOAAI
errBayer, Thomas; Palm, Gottfried J.; Berndt, Leona; Meinert, Hannes; Branson, Yannick; Schmidt, Louis; Cziegler, Clemens; Somvilla, Ina; Zurr, Celine; Graf, Leonie G.; Janke, Una; Badenhorst, Christoffel P. S.; Koenig, Stefanie; Delcea, Mihaela; Garscha, Ulrike; Wei, Ren; Lammers, Michael; Bornscheuer, Uwe T.
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Development of SFC-MS Method for Quantification of Eicosanoids Biosynthesized in Primary Human Blood Cells
err2022-11-30
err3
errOAAI
errSchmidt, Louis; Burmeister, Laura Sophie; Greinacher, Andreas; Koenig, Stefanie; Garscha, Ulrike
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Identification of 2,4-Dinitro-Biphenyl-Based Compounds as MAPEG Inhibitors
err2022-10-11
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errOAAI
errDi Micco, Simone; Terracciano, Stefania; Pierri, Martina; Cantone, Vincenza; Liening, Stefanie; Koenig, Stefanie; Garscha, Ulrike; Hofstetter, Robert Klaus; Koeberle, Andreas; Werz, Oliver; Bruno, Ines; Bifulco, Giuseppe
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Synthesis and structure-activity relationships for some novel diflapolin derivatives with benzimidazole subunit
err2022-09-20
err3
errOAAI
errVieider, Lisa; Zoeller, Eva; Romp, Erik; Schoenthaler, Martin; Hernandez-Olmos, Victor; Temml, Veronika; Hasenoehrl, Thomas; Schuster, Daniela; Werz, Oliver; Garscha, Ulrike; Matuszczak, Barbara
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Candida albicans-induced leukotriene biosynthesis in neutrophils is restricted to the hyphal morphology
err2021-09-27
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errOAAI
errFischer, Jana; Gresnigt, Mark S.; Werz, Oliver; Hube, Bernhard; Garscha, Ulrike
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Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation
err2021-07-19
err12
errOAAI
errNeukirch, Konstantin; Alsabil, Khaled; Dinh, Chau-Phi; Bilancia, Rossella; Raasch, Martin; Ville, Alexia; Cerqua, Ida; Viault, Guillaume; Breard, Dimitri; Pace, Simona; Temml, Veronika; Brunner, Elena; Jordan, Paul M.; Marques, Marta C.; Loeser, Konstantin; Gollowitzer, Andre; Permann, Stephan; Gerstmeier, Jana; Lorkowski, Stefan; Stuppner, Hermann; Garscha, Ulrike; Rodrigues, Tiago; Bernardes, Goncalo J. L.; Schuster, Daniela; Seraphin, Denis; Richomme, Pascal; Rossi, Antonietta; Mosig, Alexander S.; Roviezzo, Fiorentina; Werz, Oliver; Helesbeux, Jean-Jacques; Koeberle, Andreas
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Modulation of microRNA processing by 5-lipoxygenase
err2020-11-17
err13
errOAAI
errUebbing, Stella; Kreiss, Marius; Scholl, Friederike; Haefner, Ann-Kathrin; Sueruen, Duran; Garscha, Ulrike; Werz, Oliver; Basavarajappa, Devaraj; Samuelsson, Bengt; Radmark, Olof; Suess, Beatrix; Steinhilber, Dieter
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Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products
err2020-05-11
err149
errOAAI
errGilbert, Nathaniel C.; Gerstmeier, Jana; Schexnaydre, Erin E.; Boerner, Friedemann; Garscha, Ulrike; Neau, David B.; Werz, Oliver; Newcomer, Marcia E.
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Discovery of Novel 5-Lipoxygenase-Activating Protein (FLAP) Inhibitors by Exploiting a Multistep Virtual Screening Protocol
err2020-02-11
err12
PREAI
errOlgac, Abdurrahman; Carotti, Andrea; Kretzer, Christian; Zergiebel, Stephanie; Seeling, Andreas; Garscha, Ulrike; Werz, Oliver; Macchiarulo, Antonio; Banoglu, Erden
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Exotoxins from Staphylococcus aureus activate 5-lipoxygenase and induce leukotriene biosynthesis
err2019-12-05
err17
errOAAI
errRomp, Erik; Arakandy, Vandana; Fischer, Jana; Wolz, Christiane; Siegmund, Anke; Loeffler, Bettina; Tuchscherr, Lorena; Werz, Oliver; Garscha, Ulrike
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Impact of food polyphenols on oxylipin biosynthesis in human neutrophils
err2019-10-01
err12
PREAI
errHartung, Nicole M.; Fischer, Jana; Ostermann, Annika, I; Willenberg, Ina; Rund, Katharina M.; Schebb, Nils Helge; Garscha, Ulrike
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A 5-lipoxygenase-specific sequence motif impedes enzyme activity and confers dependence on a partner protein
err2019-04-01
err3
errOAAI
errSchexnaydre, Erin E.; Gerstmeier, Jana; Garscha, Ulrike; Jordan, Paul M.; Werz, Oliver; Newcomer, Marcia E.
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Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome
err2019-02-08
err108
errOAAI
errWerner, Markus; Jordan, Paul M.; Romp, Erik; Czapka, Anna; Rao, Zhigang; Kretzer, Christian; Koeberle, Andreas; Garscha, Ulrike; Pace, Simona; Claesson, Hans-Erik; Serhan, Charles N.; Werz, Oliver; Gerstmeier, Jana
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Melleolides from Honey Mushroom Inhibit 5-Lipoxygenase via Cys159
err2019-01-01
err14
errOAAI
errKoenig, Stefanie; Romp, Erik; Krauth, Verena; Ruehl, Michael; Doerfer, Maximilian; Liening, Stefanie; Hofmann, Bettina; Haefner, Ann-Kathrin; Steinhilber, Dieter; Karas, Michael; Garscha, Ulrike; Hoffmeister, Dirk; Werz, Oliver
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A Multi-step Virtual Screening Protocol for the Identification of Novel Non-acidic Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors
err2018-12-20
err19
PREAI
errShekfeh, Suhaib; Caliskan, Burcu; Fischer, Katrin; Yalcin, Tansu; Garscha, Ulrike; Werz, Oliver; Banoglu, Erden
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