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Multifunctional Organometallic Compounds Active against Infective Trypanosomes: Ru(II) Ferrocenyl Derivatives with Two Different Bioactive Ligands Rivas, Feriannys; Del Marmol, Carolina; Scalese, Gonzalo; Perez Diaz, Leticia; Machado, Ignacio; Blacque, Olivier; Salazar, Fabiana; Laura Coitino, E.; Benitez, Diego; Medeiros, Andrea; Comini, Marcelo; Gambino, Dinorah Share Save
Discovery of Antitrypanosomal Indolylacetamides by a Deconstruction-Optimization Strategy Applied to Paullones Lindhof, Jens C.; Ihnatenko, Irina; Mueller, Marco J.; Orban, Oliver C. F.; Ortiz, Cecilia; Benitez, Diego; Dibello, Estefania; Seidl, Leonardo L.; Comini, Marcelo A.; Kunick, Conrad Share Save
Mode of action of p-quinone derivatives with trypanocidal activity studied by experimental and in silico models Ballesteros-Casallas, Andres; Quiroga, Cristina; Ortiz, Cecilia; Benitez, Diego; Denis, Pablo A.; Figueroa, David; Salas, Cristian O.; Bertrand, Jeanluc; Tapia, Ricardo A.; Sanchez, Patricio; Miscione, Gian Pietro; Comini, Marcelo A.; Paulino, Margot Share Save
Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening Benitez, Diego; Franco, Jaime; Sardi, Florencia; Leyva, Alejandro; Duran, Rosario; Choi, Gahee; Yang, Gyongseon; Kim, Taehee; Kim, Namyoul; Heo, Jinyeong; Kim, Kideok; Lee, Honggun; Choi, Inhee; Radu, Constantin; Shum, David; No, Joo Hwan; Comini, Marcelo A. Share Save
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Mechanistic and biological characterisation of novelN5-substituted paullones targeting the biosynthesis of trypanothione inLeishmania Medeiros, Andrea; Benitez, Diego; Korn, Ricarda S.; Ferreira, Vinicius C.; Barrera, Exequiel; Carrion, Federico; Pritsch, Otto; Pantano, Sergio; Kunick, Conrad; de Oliveira, Camila, I; Orban, Oliver C. F.; Comini, Marcelo A. Share Save
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Amino Acid Block Copolymers with Broad Antimicrobial Activity and Barrier Properties Bevilacqua, Michael P.; Huang, Daniel J.; Wall, Brian D.; Lane, Shalyn J.; Edwards, Carl K., III; Hanson, Jarrod A.; Benitez, Diego; Solomkin, Joseph S.; Deming, Timothy J. Share Save
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5-Substituted 3-chlorokenpaullone derivatives are potent inhibitors of Trypanosoma brucei bloodstream forms Orban, Oliver C. F.; Korn, Ricarda S.; Benitez, Diego; Medeiros, Andrea; Preu, Lutz; Loaec, Nadege; Meijer, Laurent; Koch, Oliver; Comini, Marcelo A.; Kunick, Conrad Share Save
Identification of Novel Chemical Scaffolds Inhibiting Trypanothione Synthetase from Pathogenic Trypanosomatids Benitez, Diego; Medeiros, Andrea; Fiestas, Lucia; Panozzo-Zenere, Esteban A.; Maiwald, Franziska; Prousis, Kyriakos C.; Roussaki, Marina; Calogeropoulou, Theodora; Detsi, Anastasia; Jaeger, Timo; Sarlauskas, Jonas; Masic, Lucija Peterlin; Kunick, Conrad; Labadie, Guillermo R.; Flohe, Leopold; Comini, Marcelo A. Share Save
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9-and 11-substituted 4-azapaullones are potent and selective inhibitors of African trypanosoma Maiwald, Franziska; Benitez, Diego; Charquero, Diego; Dar, Mahin Abad; Erdmann, Hanna; Preu, Lutz; Koch, Oliver; Hoelscher, Christoph; Loaec, Nadege; Meijer, Laurent; Comini, Marcelo A.; Kunick, Conrad Share Save
Genetic and chemical analyses reveal that trypanothione synthetase but not glutathionylspermidine synthetase is essential for Leishmania infantum Sousa, Andre F.; Gomes-Alves, Ana G.; Benitez, Diego; Comini, Marcelo A.; Flohe, Leopold; Jaeger, Timo; Passos, Joana; Stuhlmann, Friedrich; Tomas, Ana M.; Castro, Helena Share Save
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