Not logged in Tunable Biased Signaling of the Angiotensin II Type 1 Receptor for Inotropy via C-Terminal Peptide Engineering and Allosteric Site Targeting Hadjadj, Margot; Hassanzadeh, Malihe; Martel, Justin; Roy, Marie-Frederique; Giguere, Hugo; Murza, Alexandre; Holleran, Brian J.; Namkung, Yoon; Froehlich, Ulrike; Leduc, Richard; Auger-Messier, Mannix; Laporte, Stephane A.; Boudreault, Pierre-Luc Share Save
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The urotensin II receptor triggers an early meningeal response and a delayed macrophage-dependent vasospasm after subarachnoid hemorrhage in male mice Pedard, Martin; Prevost, Lucie; Carpena, Camille; Holleran, Brian; Desrues, Laurence; Dubois, Martine; Nicola, Celeste; Gruel, Roxane; Godefroy, David; Deffieux, Thomas; Tanter, Mickael; Ali, Carine; Leduc, Richard; Prezeau, Laurent; Gandolfo, Pierrick; Morin, Fabrice; Wurtz, Olivier; Bonnard, Thomas; Vivien, Denis; Castel, Helene Share Save
G protein selectivity profile of GPR56/ADGRG1 and its effect on downstream effectors Jallouli, Raida; Moreno-Salinas, Ana L.; Laniel, Andreanne; Holleran, Brian; Avet, Charlotte; Jacob, Joan; Hoang, Trang; Lavoie, Christine; Carmon, Kendra S.; Bouvier, Michel; Leduc, Richard Share Save
Rational In Silico Design of Selective TMPRSS6 Peptidomimetic Inhibitors via Exploitation of the S2 Subpocket Desgagne, Michael; Desilets, Antoine; Ferkova, Sara; Lepage, Matthieu; Perreault, Olivier; Joushomme, Alexandre; Lemieux, Gabriel; Guerrab, Walid; Froehlich, Ulrike; Comeau, Christian; Sarret, Philippe; Leduc, Richard; Boudreault, Pierre-Luc Share Save
Optimization of Ketobenzothiazole-Based Type II Transmembrane Serine Protease Inhibitors to Block H1N1 Influenza Virus Replication Colombo, Eloic; Desilets, Antoine; Hassanzadeh, Malihe; Lemieux, Gabriel; Marois, Isabelle; Cliche, Dominic; Delbrouck, Julien A.; Murza, Alexandre; Jean, Francois; Marsault, Eric; Richter, Martin V.; Leduc, Richard; Boudreault, Pierre-Luc Share Save
A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants Perez-Vargas, Jimena; Worrall, Liam J.; Olmstead, Andrea D.; Ton, Anh-Tien; Lee, Jaeyong; Villanueva, Ivan; Thompson, Connor A. H.; Dudek, Svenja; Ennis, Siobhan; Smith, Jason R.; Shapira, Tirosh; De Guzman, Joshua; Gang, Shutong; Ban, Fuqiang; Vuckovic, Marija; Bielecki, Michael; Kovacic, Suzana; Kenward, Calem; Hong, Christopher Yee; Gordon, Danielle G.; Levett, Paul N.; Krajden, Mel; Leduc, Richard; Boudreault, Pierre-Luc; Niikura, Masahiro; Paetzel, Mark; Young, Robert N.; Cherkasov, Artem; Strynadka, Natalie C. J.; Jean, Francois Share Save
Unraveling allostery within the angiotensin II type 1 receptor for Gαq and β-arrestin coupling Cao, Yubo; van der Velden, Wijnand J. C.; Namkung, Yoon; Nivedha, Anita K.; Cho, Aaron; Sedki, Dana; Holleran, Brian; Lee, Nicholas; Leduc, Richard; Muk, Sanychen; Le, Keith; Bhattacharya, Supriyo; Vaidehi, Nagarajan; Laporte, Stephane A. Share Save
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Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human Hepatocytes Beliveau, Francois; Tarkar, Aarti; Dion, Sebastien P.; Desilets, Antoine; Ghinet, Mariana Gabriela; Boudreault, Pierre-Luc; St-Georges, Catherine; Marsault, Eric; Paone, Daniel; Collins, Jon; Macphee, Colin H.; Campobasso, Nino; Groy, Arthur; Cottom, Josh; Ouellette, Michael; Pope, Andrew J.; Leduc, Richard Share Save
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Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors Namkung, Yoon; LeGouill, Christian; Kumar, Sahil; Cao, Yubo; Teixeira, Larissa B.; Lukasheva, Viktoriya; Giubilaro, Jenna; Simoes, Sarah C.; Longpre, Jean-Michel; Devost, Dominic; Hebert, Terence E.; Pineyro, Graciela; Leduc, Richard; Costa-Neto, Claudio M.; Bouvier, Michel; Laporte, Stephane A. Share Save
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