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A Series of Pyrazolo-Quinazoline Amines Inhibits the Cytochrome bd Oxidase in Mycobacterium tuberculosis Singh, Samsher; Ng, Pearly Shuyi; Lakshmanan, Umayal; Mathiyazakan, Vikneswaran; Wiggins, Thomas; Lee, Bei Shi; Ang, Shi Hua; Lin Sim, Sandra Wei; Santos, May Delos; Moraski, Garrett; Miller, Marvin; Berney, Michael; Gruber, Gerhard; Pethe, Kevin Share Save
Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates Rajagopalan, Saranathan; Rourke, Amy K.; Asare, Emmanuel; Kohlerschmidt, Donna J.; Das, Lahari; Ngema, Senamile L.; Mulholland, Claire, V; Vilcheze, Catherine; Mahalingam, Vaishnavi; Moodley, Sashen; Truebody, Barry; Mackenzie, Jared; Steyn, Adrie J. C.; Perumal, Rubeshan; Berney, Michael; Larsen, Michelle H.; O'Donnell, Max R.; Escuyer, Vincent E.; Jacobs, William R. Share Save
A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis Adolph, Cara; Cheung, Chen-Yi; McNeil, Matthew B.; Jowsey, William J.; Williams, Zoe C.; Hards, Kiel; Harold, Liam K.; Aboelela, Ashraf; Bujaroski, Richard S.; Buckley, Benjamin J.; Tyndall, Joel D. A.; Li, Zhengqiu; Langer, Julian D.; Preiss, Laura; Meier, Thomas; Steyn, Adrie J. C.; Rhee, Kyu Y.; Berney, Michael; Kelso, Michael J.; Cook, Gregory M. Share Save
M. tuberculosis relies on trace oxygen to maintain energy homeostasis and survive in hypoxic environments Kalia, Nitin Pal; Singh, Samsher; Hards, Kiel; Cheung, Chen-Yi; Sviriaeva, Ekaterina; Banaei-Esfahani, Amir; Aebersold, Ruedi; Berney, Michael; Cook, Gregory M.; Pethe, Kevin Share Save
Capturing Structural Variants of Herpes Simplex Virus Genome in Full Length by Oxford Nanopore Sequencing Saranathan, Rajagopalan; Asare, Emmanuel; Leung, Lawrence; de Oliveira, Anna Paula; Kaugars, Katherine E.; Mulholland, Claire, V; Lukose, Regy; Berney, Michael; Jacobs, William R., Jr. Share Save
Combining CRISPRi and metabolomics for functional annotation of compound libraries (February, 10.1038/s41589-022-00970-3, 2022) Anglada-Girotto, Miquel; Handschin, Gabriel; Ortmayr, Karin; Campos, Adrian I.; Gillet, Ludovic; Manfredi, Pablo; Mulholland, Claire V.; Berney, Michael; Jenal, Urs; Picotti, Paola; Zampieri, Mattia Share Save
An amiloride derivative is active against the F1Fo-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis Hards, Kiel; Cheung, Chen-Yi; Waller, Natalie; Adolph, Cara; Keighley, Laura; Tee, Zhi Shean; Harold, Liam K.; Menorca, Ayana; Bujaroski, Richard S.; Buckley, Benjamin J.; Tyndall, Joel D. A.; McNeil, Matthew B.; Rhee, Kyu Y.; Opel-Reading, Helen K.; Krause, Kurt; Preiss, Laura; Langer, Julian D.; Meier, Thomas; Hasenoehrl, Erik J.; Berney, Michael; Kelso, Michael J.; Cook, Gregory M. Share Save
Combining CRISPRi and metabolomics for functional annotation of compound libraries Anglada-Girotto, Miquel; Handschin, Gabriel; Ortmayr, Karin; Campos, Adrian I.; Gillet, Ludovic; Manfredi, Pablo; Mulholland, Claire V.; Berney, Michael; Jenal, Urs; Picotti, Paola; Zampieri, Mattia Share Save
Mycobacterium tuberculosis H2S Functions as a Sink to Modulate Central Metabolism, Bioenergetics, and Drug Susceptibility Kunota, Tafara T. R.; Rahman, Md Aejazur; Truebody, Barry E.; Mackenzie, Jared S.; Saini, Vikram; Lamprecht, Dirk A.; Adamson, John H.; Sevalkar, Ritesh R.; Lancaster, Jack R., Jr.; Berney, Michael; Glasgow, Joel N.; Steyn, Adrie J. C. Share Save
Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis Lee, Bei Shi; Hards, Kiel; Engelhart, Curtis A.; Hasenoehrl, Erik J.; Kalia, Nitin P.; Mackenzie, Jared S.; Sviriaeva, Ekaterina; Chong, Shi Min Sherilyn; Manimekalai, Malathy Sony S.; Koh, Vanessa H.; Chan, John; Xu, Jiayong; Alonso, Sylvie; Miller, Marvin J.; Steyn, Adrie J. C.; Gruber, Gerhard; Schnappinger, Dirk; Berney, Michael; Cook, Gregory M.; Moraski, Garrett C.; Pethe, Kevin Share Save
Derailing the aspartate pathway of Mycobacterium tuberculosis to eradicate persistent infection Hasenoehrl, Erik J.; Sajorda, Dannah Rae; Berney-Meyer, Linda; Johnson, Samantha; Tufariello, JoAnn M.; Fuhrer, Tobias; Cook, Gregory M.; Jacobs, William R., Jr.; Berney, Michael Share Save
Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex Chiner-Oms, Alvaro; Berney, Michael; Boinett, Christine; Gonzalez-Candelas, Fernando; Young, Douglas B.; Gagneux, Sebastien; Jacobs, William R., Jr.; Parkhill, Julian; Cortes, Teresa; Comas, Inaki Share Save
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Synthesis and degradation of FtsZ quantitatively predict the first cell division in starved bacteria Sekar, Karthik; Rusconi, Roberto; Sauls, John T.; Fuhrer, Tobias; Noor, Elad; Nguyen, Jen; Fernandez, Vicente I.; Buffing, Marieke F.; Berney, Michael; Jun, Suckjoon; Stocker, Roman; Sauer, Uwe Share Save
Arginine-deprivation-induced oxidative damage sterilizes Mycobacterium tuberculosis Tiwari, Sangeeta; van Tonder, Andries J.; Vilcheze, Catherine; Mendes, Vitor; Thomas, Sherine E.; Malek, Adel; Chen, Bing; Chen, Mei; Kim, John; Blundell, Tom L.; Parkhill, Julian; Weinrick, Brian; Berney, Michael; Jacobs, William R., Jr. Share Save
The Capacity of Mycobacterium tuberculosis To Survive Iron Starvation Might Enable It To Persist in Iron-Deprived Microenvironments of Human Granulomas Kurthkoti, Krishna; Amin, Hamel; Marakalala, Mohlopheni J.; Ghanny, Saleena; Subbian, Selvakumar; Sakatos, Alexandra; Livny, Jonathan; Fortune, Sarah M.; Berney, Michael; Rodriguez, G. Marcela Share Save
Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection Kalia, Nitin P.; Hasenoehrl, Erik J.; Ab Rahman, Nurlilah B.; Koh, Vanessa H.; Ang, Michelle L. T.; Sajorda, Dannah R.; Hards, Kiel; Gruber, Gerhard; Alonso, Sylvie; Cook, Gregory M.; Berney, Michael; Pethe, Kevin Share Save
Oxidative Phosphorylation as a Target Space for Tuberculosis: Success, Caution, and Future Directions Cook, Gregory M.; Hards, Kiel; Dunn, Elyse; Heikal, Adam; Nakatani, Yoshio; Greening, Chris; Crick, Dean C.; Fontes, Fabio L.; Pethe, Kevin; Hasenoehrl, Erik; Berney, Michael Share Save
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